0

the use of expert systems for toxicity prediction illustrated with reference to the derek program

Predicting Chemical Toxicity and Fate - Section 3 ppt

Predicting Chemical Toxicity and Fate - Section 3 ppt

Cao đẳng - Đại học

... CHAPTER The Use of Expert Systems for Toxicity Prediction: Illustrated with Reference to the DEREK Program Robert D Combes and Rosemary A Rodford CONTENTS I Introduction A The Nature of Expert Systems ... oxygen-oxygen bond and the formation of the carbon-oxygen bond between the C3 atom of the substrate and the distal oxygen of the peroxide moiety of the cofactor Changes in the conformation of amino acids ... similar to those in the data set used to derive them For the generation of more useful QSARs, the need to increase the structural diversity of the training set was noted by the authors The use of...
  • 89
  • 681
  • 0
Báo cáo y học:

Báo cáo y học: " Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis"

Y học thưởng thức

... on the same day or within month of biologic initiation The date of initiation of the biologic defined the start of a one year ‘treatment episode’, which began on the ‘index date’ In order to ... data were used only to capture the DAS28, the CDAI and other clinical characteristics measured at the baseline and outcome VARA visits; all other data used for the analysis were from the administrative ... contrast to other RA therapies where the drugs are typically discontinued if they are not effective Because of similarities in both the descriptive characteristics of the study populations of biologic...
  • 29
  • 581
  • 0
Comparison of Methods for the Extraction of Bioflocculants from Activated Sludge

Comparison of Methods for the Extraction of Bioflocculants from Activated Sludge

Môi trường

... of 70 ml and 90 ml) and one UV-absorbing peak (at elution volume of 95 ml) The A280 to A260 ratio of the UV-absorbing peak indicated it was composed mainly of nucleic acid In the profile of the ... mainly of protein, was unexpected Figure shows the effect of concentration of the NaOH-extracted polymer (2.5 to 20 ppm) on activity in the presence of mM calcium ions The activity correlated with ... included a larger amount of saccharides (24.6%) compared to the other methods The SDS-extracted polymer included a small amount of material other than protein Furthermore, the steaming- and washing-extracted...
  • 11
  • 695
  • 1
Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders ppt

Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders ppt

Cao đẳng - Đại học

... injuries with loss of sight, the formation of blisters on the skin, nausea, vomiting, and diarrhea together with severe difficulty in breathing Severe damage to the eye may lead to the total loss of ... Statistics, the Office of Juvenile Justice and Delinquency Prevention, and the Office for Victims of Crime U.S Department of Justice Office of Justice Programs National Institute of Justice Guide for the ... rapidly with the C6 H5 SO2N-H anion to form a sulfimide species and with water to form sulfur mustard For VX, it was found that VX does not react with the Chloramine-B in the towelette because the...
  • 96
  • 705
  • 0
Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders pdf

Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders pdf

Cao đẳng - Đại học

... Statistics, the Office of Juvenile Justice and Delinquency Prevention, and the Office for Victims of Crime U.S Department of Justice Office of Justice Programs National Institute of Justice Guide for the ... endorsement by the U.S Department of Justice The National Institute of Justice is a component of the Office of Justice Programs, which also includes the Bureau of Justice Assistance, the Bureau of Justice ... refers to the level of education and training required for the individual to operate the equipment 3.5.2 Operator Training Required The Operator Training Required data field refers to the amount of...
  • 186
  • 600
  • 0
nmr methods for the investigation of structure and transport

nmr methods for the investigation of structure and transport

Đại cương

... due to the time-dependence of the unit vectors Using the product rule for the derivation and the fact that the time derivative of the unit vector is the cross product of !rf with this vector ... [56], the dipole vector is replaced by the corresponding vector operator O and the energy by the Hamilton operator: O H0 D O B0 : (2.2) O The magnetic-dipole vector operator is proportional to the ... by r/ in the vicinity of the right boundary of the FOV Still for a rather coarse discretization of N D 32 the corresponding sum is shown in Fig 2.3b The first point of the result vector with n D...
  • 223
  • 786
  • 0
báo cáo hóa học:

báo cáo hóa học: " The evolution of methods for the capture of human movement leading to markerless motion capture for biomechanical applications" pptx

Hóa học - Dầu khí

... resource of knowledge related to the mechanics of human movement The work at the University of California formed the basis for many of the fundamental techniques currently used for the study of human ... factors limiting the advancement of the study of human movement is the measurement of skeletal movement from markers or sensors placed on the skin The movement of the markers is typically used to ... need to capture the kinematics and kinetics of human movement without the constraints of the laboratory or the encumbrance of placing markers on the limb segments Second, we need to relate the...
  • 11
  • 511
  • 0
báo cáo hóa học:

báo cáo hóa học:" Biomechanical testing of a polymer-based biomaterial for the restoration of spinal stability after nucleotomy" pptx

Hóa học - Dầu khí

... restoration The individual NZ for all samples, however, were restored to values similar to the intact spinal segments Thus, implantation of the PGA-HA biomaterial has the capability to restore the ... Thereupon, the implant was roped into the annulus defect and attached to the inner wall of the annulus fibrosus The sutures were then fixated by surgical knots at the outer surface of the annulus ... wall of the annulus fibrosus Ideally, the suture penetrates the annulus close to the vertebral endplate The sutures are then fixated by surgical knots at the outer surface of the annulus Page of...
  • 9
  • 457
  • 0
Báo cáo hóa học:

Báo cáo hóa học: " A quantum dots and superparamagnetic nanoparticle-based method for the detection of HPV DNA" ppt

Hóa học - Dầu khí

... times with the abovementioned method; the means were used to determine the cutoff value According to the data, the cutoff value of this assay was defined as 14.5, any result under 14.5 from the ... of Milli-Q water under N protection One molar NaOH solution was used to Page of adjust the pH of the mixture to 9.1 under stirring The NaHTe solution prepared in the first step was added to the ... Page of predenatured at 95°C for 10 min, then 55°C for 30 The particles coupled with streptavidin were added into the hybridization mixtures and incubated at 37°C for 10 and enriched in the bottom...
  • 9
  • 469
  • 0
Cocoa Processing Methods for the Production of High Quality Cocoa in Vietnam ppt

Cocoa Processing Methods for the Production of High Quality Cocoa in Vietnam ppt

Báo cáo khoa học

... Fresh Pods 35 Pods stored for days 30 25 20 Day of Fermentation Figure 4: The effect of pod storage on the fermentation temperatures of cocoa During pod storage, the beans within the pod loose moisture ... weeks when there are not too many pods When pods are cut from the tree, they should be cut with a sharp implement This is to make sure the pod stem is cut off cleanly, without damage to the flower ... shovel or hands to help get air into the fermenting cocoa and to help make the fermentation even throughout the cocoa When more air gets into the cocoa, as a result of turning, the rate of fermentation...
  • 18
  • 558
  • 0
Standard Methods for the Examination of Water and Wastewater P4. end

Standard Methods for the Examination of Water and Wastewater P4. end

Hóa học - Dầu khí

... nonconductive, they severely distort the signal in the detector; therefore, many systems remove the bubbles before the optical light path However, if the system removes the bubbles at any point within the ... consequent formation of HCN The great toxicity to aquatic life of molecular HCN is well known;2-5 it is formed in solutions of cyanide by hydrolytic reaction of CN– with water The toxicity of CN– ... determination of the total of these cyanides (H, N, and O) Repeating the test with the cyanide masked by the addition of formaldehyde provides a measure of the SCN– content When subtracted from the earlier...
  • 733
  • 718
  • 0
Standard Methods for the Examination of Water and Wastewater P3

Standard Methods for the Examination of Water and Wastewater P3

Hóa học - Dầu khí

... Classification of the Marine Phytoplankton of the World from Class to Genus Phycologia 32:159 ROUND, F.E., R.M CRAWFORD & D.G MANN 1990 The Diatoms: Biology and Morphology of the Genera Cambridge ... Standard Methods for the Examination of Water and Wastewater Organism Plate 10900 E Selected Taxonomic References The most useful references for the nonspecialist are listed below These references ... Washington, D.C ABBOTT, I.A & G.J HOLLENBERG 1976 Marine Algae of California Stanford Univ Press, Stanford, Calif EDWARDS, P 1976 Illustrated Guide to the Seaweeds and Sea Grasses in the Vicinity of...
  • 72
  • 449
  • 1
Standard Methods for the Examination of Water and Wastewater P2

Standard Methods for the Examination of Water and Wastewater P2

Hóa học - Dầu khí

... Examination of Water and Wastewater Diatoma © Copyright 1999 by American Public Health Association, American Water Works Association, Water Environment Federation Standard Methods for the Examination of ... for the Examination of Water and Wastewater Synedra © Copyright 1999 by American Public Health Association, American Water Works Association, Water Environment Federation Standard Methods for the ... Examination of Water and Wastewater Ceratium © Copyright 1999 by American Public Health Association, American Water Works Association, Water Environment Federation Standard Methods for the Examination of...
  • 163
  • 721
  • 3
Standard Methods for the Examination of Water and Wastewater P1

Standard Methods for the Examination of Water and Wastewater P1

Hóa học - Dầu khí

... compound is referenced The use of such a name is intended only to be a shorthand reference for the functional characteristics of the manufacturer’s item These references are not intended to be an ... The atomic weights of many elements are not invariant but depend on the origin and treatment of the material The standard values of Ar(E) and the uncertainties (in parentheses, following the © ... Methods for the Examination of Water and Wastewater last significant figure to which they are attributed) apply to elements of natural terrestrial origin The footnotes to this Table elaborate the...
  • 19
  • 725
  • 1
Báo cáo khoa học:

Báo cáo khoa học: "Comparison of Diagnostic Methods for the Detection of Parasites in Fish" pdf

Báo cáo khoa học

... (not hotter to avoid plastic deformation) on the table and poured into the gel frame which had been sealed at the ends with autoclave tape The gel comb making the wells was added The gel then polymerized ... containing PBS The objectives of the present study were to investigate the use of different methodologies in fish parasite studies Thus, the aim is to compare classical and molecular methods for the diagnosis ... demonstration of the life history is frequently unachievable due to the unidentified nature of the specific intermediate or definitive host The use of molecular methodologies has allowed links to be...
  • 9
  • 559
  • 0
Báo cáo khoa học:

Báo cáo khoa học: " Effective methods for the production of immunoglobulin Y using immunogens of Bordetella bronchiseptica , Pasteurella multocida and Actinobacillus pleuropneumoniae" docx

Báo cáo khoa học

... indicate that the toxicity of P multocida A:3 in hens, as indicated by a reduction of egg production and increases with mortality Survival rates of experimental groups (1 to 4) injected with the causative ... Immune responses to P multocida A:3 Immune response profiles against P multocida A:3 in egg yolks and the sera of hens immunized with P multocida A:3 alone and P multocida A:3 combined with A pleuropneumoniae ... after mixing with an equal volume of PBS The homogenized egg yolk was then mixed with two volumes of chloroform and incubated for hrs at room temperature After this incubation, the supernatant...
  • 11
  • 388
  • 0
Báo cáo khoa học:

Báo cáo khoa học: " Comparison of two sap flow methods for the estimation of tree transpiration" ppt

Báo cáo khoa học

... functioning of each method was not deteriorated by the other The relationship obtained with the comparison of the two methods over the whole period (n 589) is presented in figure The slope of the regression ... possibility of experiment one or the other method in accordance with the objectives, and the equipment The major problem is still the choice of samples required for an accurate estimation of transpiration ... easy control of the sensors, the low energy needs and the low number of datalogger connections The transpiration was calculated on the basis of sapwood area which represented 90 % of the crosssectional...
  • 7
  • 326
  • 0
Báo cáo sinh học:

Báo cáo sinh học: "Use of sib-pair linkage methods for the estimation of the genetic variance at a quantitative trait locus" pps

Báo cáo khoa học

... linkage of markers with a QTL and then use Method I for the estimation Unfortunately, Fulker and Cardon (1994) give little information about the quality of their estimator of the QTL variance The ... (1992) found that the use of fully informative matings can increase the power of the Haseman-Elston test for a given number of genotypings Consequently, only these matings were used in the calculations ... markers for a given QTL, the principle of sib-pair linkage methods can be applied to obtain estimates of the QTL variance and to locate the QTL in the interval The simulation study made use of the...
  • 14
  • 299
  • 0
Báo cáo y học:

Báo cáo y học: "An alternative methodology for the prediction of adherence to anti HIV treatment" ppt

Báo cáo khoa học

... allow for the level of adherence to drug therapy regimes to be monitored Additionally, such an analysis would facilitate a more accurate assessment of the progression of the patient in terms of their ... treatments often so because they 'simply forgot' [30] Presentation of the hypothesis The importance of having accurate information on adherence is underscored by the fact that in order to achieve ... months in patients with HIV The limitations of this hypothesis as applied to clinical practice include the access to and costs of sequencing Therefore, it is envisaged that the hypothesised approach...
  • 6
  • 447
  • 0
báo cáo khoa học:

báo cáo khoa học: " Social networks, work and network-based resources for the management of long-term conditions: a framework and study protocol for developing self-care support" potx

Báo cáo khoa học

... nonhealth professionals, and, to a more limited extent, health professionals The distribution of the responsibilities for LTCM between groups of involved actors outside of the immediacy of the health ... symptoms), and increases people’s ability to cope with their condition iv One of the unanticipated benefits of self-management programmes such as the Expert Patients’ Programme has been the potential ... properties of systems of support for LTCM outside services with their links to the healthcare system We will evaluate the acceptability, effectiveness, and economic efficiency of the interventions,...
  • 7
  • 331
  • 0

Xem thêm