... that is wellsuited to binding of proteins or nucleic acids. This topology has been found inthe armadillo repeat(found in b-catenins and a-importins such as the b-subunit of karyopherin). The ... His6-tagged apoprotein and the resultingincrease in absorption and band-shift can be followedspectroscopically. Phycocyanin can also add to the acceptor protein spontaneously, generating a weakunspecific ... prolifera-tion ofthe parasite and isan essential substrate in the biosynthesis of hypusine [N(epsilon)-(4-amino-2-hy-droxybutyl) lysine], a novel amino acid present in eukaryotic initiation factor-5A...
... occurred within him whichis felt by the human being to the very depths of hissoul, and makes of him a new creature. It isinthis sense that the theory ofthe romanticists, with regard to the Information ... boringpeople, of boring them as life itself does. And yet what is more interesting than the history ofthe heart, whenit is a true history? The main thing is to write true history, and it is ... Tarbes, and the scene ofthe story is laid inthe region of the Pyrenees, in Tarbes Auch, Nerac, the Landes, and finishes with the return to Paris. Rose, after an entertainment whichis a veritable...
... forms of crisis of SCP. Thus, the next step inthe development of a theory of capitalist crisis isan analysis ofthe crisis tendencies of capitalist production relations and an examination ofthe ... misinterpreted as an argument that the financial system is an unimportant aspect of his crisis theory. It isthis misinterpretation that we wish to correct. In the remaining sections ofthis ... Crisis, and the Multicausal Tendency of the Rate of Profit to Fall The rate of profit isthe key variable inthe Marxian theory ofthe dynamics of accumulation and crisis in capitalism. The...
... thatNrdI is involved inthe assembly of a MnIII-MnIII-Tyr°cofactor in E. coli and that thisisthe true cofactor in vivo. However, this hypothesis does not exclude the possibility that the cofactor ... the N-terminus of a1 and the preceding P-loop. The flavinmoiety of FMN binds in a pocket formed by loops at the C-terminal ends of b-strands 3 and 4 (loops 42–49and 71–79, respectively), known in ... preponderance of acidic side chains inthe vicinity ofthe flavin in cbFld, including two inthe 50s loop itself. There arethree acidic residues within 6 A˚, and a further fourwithin 10 A˚....
... specificity ofthe action ofan antiviral compound is determined by calculating the Therapeutic Index (TI), which isthe ratio of CC50 to IC50. The TI of SCH 16 was5 and 19 for JEV and WNV respectively ... purposes)potential and specificity of action was determined by cal-culating the Therapeutic Index (TI), whichisthe ratio of CC50 to IC50 (CC50/IC50) [37].Understanding the mechanism of action of ... amount of infectious virus (50LD50) into the CNS which might have compromised the inhibitoryaction of SCH 16 and/or (ii) inability to achieve therapeu-tic concentrations ofthe drug inthe brain...
... the use of monitoring,including capnography. We anonymised the involvedHEMS physicians and recorded them as “anaesthesiologistspecialist” or “resident”. In cases inwhichthe components of RTS ... during the study period. There was nospecific difficult airway algorithm inthe service in the period other than the one available inthe anaesthesiol-ogy department under which it is organised. ... operative initialtraining and checking. Pre-hospital ETI is performed at the discretion ofthe treating physician, and a variety of anaesthetic drugs are available to facilitate ETI. Writtenguidelines...
... This example displays: ProductID database type = int As you can see, the ProductID column isofthe SQL Server int type. Listing 9.2 uses the code examples shown inthis section. Listing ... Explorer. For example, Figure 9.1 shows the details ofthe ProductID column ofthe Products table. As you can see, ProductID isan int. Figure 9.1: Obtaining the type of a column using Visual Studio ... value, the GetString() method is used. Of course, this code depends on your knowing the type ofthe database column. If you don't know the type of a column, you can get it using Visual...
... unitsInStock); SqlBoolean discontinued = productsSqlDataReader.GetSqlBoolean(discontinuedColPos); Console.WriteLine("discontinued = " + discontinued); } Listing 9.3 uses this ... types and the standard C# types, whichthe Get* methods have to do. Tip If you are using SQL Server, always use the GetSql* methods and Sql* types rather than the Get* methods and the standard ... earlier. For example, the ProductID column is a SQL Server int, and looking up that type in Table 9.7, you can see you use the GetSqlInt32() method to obtain the column value as a C# SqlInt32. Table...
... venom. Thisisthe firstrecombinant human antibody fragment that neutralizesC. noxius venom. To the best of our knowledge, thisis the first report ofthe generation of a human recom-binant antibody ... of a recombinant antiserumagainst Centruroides stings. These results open newavenues for the generation of recombinant antiseraagainst deadly animals.Experimental proceduresAntigensToxin ... shortening ofthe linker peptide(unpublished results), resulted inan improvement in the stability ofthe single chain. The diabodies of evolved clones 6F and 610A were constructed by shor-tening...
... impact on the remainder of the project, management should be well aware ofthe activities carriedout in connection with the way they are handled and of their by-products. The importance of management ... fail. This is precisely what we, at GRafP Technologies, wanted to analyze andquantify, particularly the thousands of interactions that lead to deterioration of a situation, often to the point of ... full engineering discipline. The equipment needed todevelop software is getting cheaper by the month and any individual withsome talent and perseverance can have a go at it. There is no need...
... that the Brazilian version has satisfactory per-formance and, thus, can be applied in different studiesreliably.Another relevant issue regarding the findings ofthe AAQvalidation isthe construct ... characteristics. Table 2 illustrates the Ancovafindings, indicating that the statistical difference in the distribution of these variables between the two samplesdoes not interfere significantly ... differ significantly between the two samples and raises the question of whether these sim-ilarities remain or not in other different cultures. The demonstration of cultural invariance ofthe core...
... item and subscale correlations and internal relia-bility. No missing values were found in any ofthe 44items inthe Brazilian sample. The analysis ofthe pooledinternational data indicated the ... Group in developing quality of life measures[16,17]. This includes translation and back-translation of the items and instructions by distinct professionals, aswell as semantic and formal examination ... that the Brazilian version has satisfactory per-formance and, thus, can be applied in different studiesreliably.Another relevant issue regarding the findings ofthe AAQvalidation isthe construct...