... as the binding constants and the extent of autoregulation The regulatory proteins may reside either inthe nucleus or inthe cytoplasm or in both, thus controlling the network The existence of ... model provide insights into the importance of their roles inthe overall performance ofthe network A similar experimental evaluation ofthe roles of individual elementary mechanisms invivo is very ... mechanism that controls the protein expression inthe wild-type is the shuttling of Gal80p Increasing the amount of Gal80p inthe cytoplasm by increasing the distribution coefficient (K) causes the...
... harvested, cleaned of soft tissue, and fixed in 70% ethanol The femur bone was trimmed above and below the ends ofthe implant, cleaned of soft-tissue, and fixed in 70% alcohol The specimen was further ... developed intestinal obstruction after ingesting surgical dressing and was euthanized days before schedule The femora were harvested from this rabbit and included inthe SEM analysis The details of ... (with an acid resistant mask) and chemical milling with nitric and hydrofluoric acid The details regarding the chemical texturing process and the osseointegration of chemical-textured implants...
... inthe delineation ofthe brachytherapy catheters during treatment planning due to partial volume effects inthe planning CT Retraction ofthe catheters within the catheter tracks during transfer ... from the coordinates ofthe catheter skin entry site and the catheter tip inthe treatment planning CT If more than one catheter was implanted, an average MA+ Lesion Page of 10 coordinate from the ... mm and of interstitial edema (T2-w images) -5 ± 6.0 mm in plane, indicating a shift ofthe irradiation effect volume against the corresponding tolerance dose volume inthe direction ofthe catheter...
... involved in joint inflammation during an acute response that may offer insight into early proinflammatory cytokine release inthe initial phases ofthe inflammatory response This is often lost by using ... per the manufacturer's instructions Blots were scanned and analyzed for band intensities by using UN-SCAN-IT version 5.1 software (Silk Scientific, Orem, UT, USA) Transient transfection of human ... killed, and joints and serum were collected at 24 and 48 hours after zymosan administration Only hind joints were used inthe study Joints were removed directly below the hairline and snap frozen in...
... Science Council in Taiwan (grant NSC94-2320-B-009-003) and the Bureau of Animal and Plant Health Inspection and Quarantine Council of Agriculture in Taiwan (grants 95AS-13.3.1-BQ-B1 and 95AS-13.3.1-BQ-B6) ... microscopy can detect GNPs by measuring this enhancement Ex vivo diffusion of GNPs into liver tissues was also performed to verify the enhancement ofthe Raman signal Localized enhancement ofthe anti-Stroke ... diffusion into the liver, lung, and spleen 123 862 Fig ELISA of GNPs using anti-endotoxin IgG ELISA was performed by using anti-endotoxin IgG against various sizes of GNPs synthesized inthe lab...
... among the five strains There are nine unique amino acids inthe RNase/ RT of BLV ARG 38 relative to all ofthe other BLV strains, including BLV ARG41 There are no differences between the integrases ... promoters of RNA transcription, the polyadenylation site (PAS), the CAP site and the tRNA proline primer binding sites are as shown The env leader peptides and the transmembrane gp30 env proteins of ... ends ofthe various proteins are indicated by the up arrow Stop codons are indicated by asterisks Only a portion ofthe BLV A Tax is shown, and the rest is indicated by thean wavy lines In the...
... among the five strains There are nine unique amino acids inthe RNase/ RT of BLV ARG 38 relative to all ofthe other BLV strains, including BLV ARG41 There are no differences between the integrases ... promoters of RNA transcription, the polyadenylation site (PAS), the CAP site and the tRNA proline primer binding sites are as shown The env leader peptides and the transmembrane gp30 env proteins of ... ends ofthe various proteins are indicated by the up arrow Stop codons are indicated by asterisks Only a portion ofthe BLV A Tax is shown, and the rest is indicated by thean wavy lines In the...
... overall incidence of PTLD is - 2% The incidence ofthe disease in renal and liver transplant is – 5%, in heart and heart-lung transplant is – 15%, and in intestinal transplant is 10 – 15% 125 The incidence ... with the type of organ transplanted, the age ofthe patient and the intensity ofthe immunosuppressive regime used The highest rate of PTLD is seen inthe first year post- transplant124 The overall ... cells in solid organ transplant patients and from recipient cells in bone marrow transplant patients A hypothetical role of latent EBV proteins inthe pathogenesis of PTLD has been explained in the...
... interpretation ofthe factors and then processing ofthe completed questionnaire and reporting The second part ofthe work also includes the validation and discussion on the results obtained Scheme ofthe ... for Individual Linkage 4.4.1 The Goal The goal ofthe single problem is primarily considered to identify the strength ofthe individual linkage by determining the relative importance ofthe linkage ... Different Characteristics of University and GRI units 13 3.1 An example ofin and out flow of factors inthe innovation triangle linkage 21 3.2 Type of Linkages inthe Innovation Triangle 23 4.1 Budget...
... containing the helper plasmid pKD46 Transformants were incubated h at 37 °C and overnight at room temperature in SOC medium and then plated on Luria–Bertani agar plates containing kanamycin Kanamycin ... Department ofthe Weizmann Institute by a single injection of 150 lg ofthe purified protein, followed by two booster shots ofthe same amount of protein at 2-week intervals Serum was collected and used ... between the amounts of UP12 and the total amount of protein inthe extracts, a series of samples containing determined amounts ofthe purified UP12 were separated by SDS/PAGE along with the cell...
... take the survey but, because ofthe small number of diabetic patients that we can find within a facility (39 in our case) and the difficulty of repeating coordinated activities of this type inthe ... bearing in mind that some inmates had to abandon the study due to different reasons Recruiting them afterwards for the study would have meant misrepresenting the results as a result ofthe inmates ... studies indicate that social inequality can be responsible of increases inthe prevalence of some diseases such as DM2 while, on the other hand, the provision and quality of primary care services can...
... turnover of airway dendritic cells is in uenced by thein ammatory state ofthe lungs [24] and that these cells play an essential role both inthe induction and maintenance of allergen-driven eosinophilic ... that the clearance and further metabolism ofthe allergen was altered as a result ofthein ammation inthe lungs of sensitized animals Up to now there are few data available on the fate ofan ... proportion of radioactivity was detected inthe lungs of sensitized mice than in nonsensitized animals The distribution of radioactivity inthe other investigated organs did not differ due to the sensitization...
... 1) are on the transside ofthe thylakoid, or that they are shielded from trypsin digestion on the cis-side ofthe membrane The A B 4004 Fig Determination ofthe topology of PSI-G inthe thylakoid ... plants expressing similar levels of PSI-G, and analysed by immunoblotting, using antibodies to PSI-G and PSI-F, as an indicator ofthe relative content of PSI inthe samples Plants lacking PSI-G ... trypsin, probed with antibodies directed against PSI-G, PSI-K (intrinsic membrane protein, stromal loop), PSI-O (intrinsic membrane protein, luminal loop) and PSI-D (extrinsic membrane protein,...
... that these inhibitory domain–domain interactions are relieved by binding ofthe metal to the N-terminus ofthe ATPase To further study the role ofthe Ccc2 N-terminus inthe overall function ofthe ... [36,37] The current hypothesis involves domain–domain interactions between the N-terminus and other domains ofthe ATPase Indeed, in vitro studies ofthe purified N-terminus and catalytic loop ofthe ... that these two domains interact inthe absence of copper and that their interaction is diminished by copper binding to the N-terminus [38] Such a domain–domain interaction has been proposed to hinder...
... calpain degradation Results Levels of HSP90 and NOS isozymes in rat brain and aorta The level of HSP90 and the type of NOS isoform present in rat brain and aorta were determined by immunoblotting ... provide a new insight into the understanding ofthe mechanisms involved in modulating NO production In such a case, the availability of adequate amounts of HSP90 becomes the limiting factor Our ... quantitative by the use of known amounts of proteins submitted to SDS-PAGE and staining with the appropriate antibody The bands were then scanned, and the areas ofthe peaks obtained were used to create...
... reported as the final molar concentration inthe organ bath Endothelium-independent vasorelaxation was tested after mechanical endothelium removal ofthe endothelial layer Surgical Induction of Hindlimb ... and slides were counterstained with a standard mixture of hematoxylin and eosin [4] Quantitative analysis was done by counting the total number of endothelial cells, identified by lectin staining ... we examinated theinvivo effects of a VEGF165 mimetic, named QK, modeled on the region ofthe VEGF protein responsible for binding to and activating the VEGFRs that are known to trigger angiogenesis...
... Dif- Page of 13 ferently, using the anti-ErbB-2 antiserum cross reacting with the murine receptor resulted in a faint stain ofthe cytoplasm and rarely in staining ofthe membrane ofthe tumor ... demonstrating the inverse correlation ofthe expression ofthe two tumor relevant molecules and implying their functional link Discussion The understanding ofthe mechanism responsible for theinvivo ... positive staining ranging from moderate to intense staining Inthe context ofthe potential association of htid expression with the biology of human breast cancers of different subtype the immunohistochemical...
... the ATFL and CFL in- vivoThe objective ofthe current study was to measure the change in apparent length ofthe ATFL and CFL, in- vivo, in uninjured healthy ankles during a dorsiflexion-plantarflexion ... during an inversion injury to the ankle.[23] These cadaveric studies have provided fundamental knowledge for the understanding of function of these ligaments and injury mechanisms However, the in- vivo ... Epidemiology of sprains inthe lateral ankle and foot Foot Ankle Int 1994, 15(2):72-4 Freeman MA: Instability ofthe foot after injuries to the lateral ligament ofthe ankle J Bone Joint Surg Br...
... increasing resonance frequencies The graph change in shape and position is more important at the beginning ofthe insertion when the stem displacement is important as well At the end ofthe insertion, ... corroborated and further elucidated by recent advanced finite element analyses by our group [25,29] During the insertion ofthe uncemented stem the FRF change is influenced by the stiffness ofthe implant-femur ... insertion stages and canal and reinserting the prosthesis The FRF had a normal evolution during the reinsertion and the graphs corresponding to the final two stages, labelled as stage 4a and stage 5a,...
... gastrointestinal tract of animals However, not all strains of Bacillus are equally resistant to the environment inthe gastrointestinal tract and antimicrobial activity varies between strains (Chang ... through the small intestine (Huang and Adams 2004) The experimental results of Casula and Cutting (2002) suggest that B subtilis germinates inthe jejunum and ileum The adverse conditions inthe ... Faeces from the negative control and the diet containing spores that performed best during the performance trial were analyzed Statistical analysis Inthe screening experiment, the counts of viable...