... Program, Laboratory of Pathology, National CancerInstitute, National Institutes of Health, Bethesda, MD 20892, USAFull list of author information is available at the end ofthe articleTakikita ... HNSCC and isa potential candidate molecule for targeted therapy.Background The majority of tumors that arise inthe head and neckregion are s quamous cell carcin omas arising from the upper aerodigestive ... immunohistochemistry for Her2 (a, membranous staining and Her3 (b, membranous andcytoplasmic staining, and c, predominant cytoplasmic staining) 400 × magnification.Takikita et al. Journal of Translational...
... equally1Tissue Array Research Program, Laboratory of Pathology, National CancerInstitute, National Institutes of Health, Bethesda, MD 20892, USAFull list of author information is available at ... Research Program, Laboratory of Pathology, National CancerInstitute, National Institutes of Health, Bethesda, MD 20892, USA.2AppliedMolecular Pathology Laboratory, Laboratory of Pathology, National ... HealthSystem and office of Human Subjects Research at the NIH. Information on post-operative radiation and /or chemotherapy, a nd performance status of patients wasunavailable for analysis.Tissue...
... simulation A mathematical model was developed, representing centralcarbohydrate metabolism in leaves of A. thaliana. The model was based on the following system of ordinary dif-ferential equations ... differences in cold-induced reprogramming of central carbohydratemetabolism. Mathematical modelling of metabolismwith respect to the dynamics of freezing tolerancerevealed a significant correlation of ... engineering of freezing tolerance in plants should include such ananalysis ofthe dynamics of metabolism to gain com-prehensive information about the effects of individualoverexpression or...
... aircraftNASA National Aeronautics and Space AdministrationNATO North Atlantic Treaty OrganizationNAVAIR Naval Air Systems CommandNGC Northrop Grumman CorporationOPNAV Office ofthe Chief of ... next explore the sources of escalation within a single aircraft program at a more detailed level, such as the airframe, propulsion, or avionics. For example, in earlier analyses of naval ship ... use of labor and tooling when production rates are higher.When considering comparison pairs of aircraft, we found that complexity ofthe aircraft (performance characteristics and airframe material)...
... Ultimately, the ophthalmologist and internistshould increase their awareness and understanding of TB and its possible ocular involvement because the dis-ease is curable and blindness is preventable ... tuberculosis, Prevalence, Anti-tubercular therapy, Extra-pulmonary TB, Anterior uveitis,Posterior uveitisBackgroundAccording to the World Health Organization, the Philippines ranks fourth inthe world ... yearly [1], making it a major public health concern in the country. TB inthe Philippines ranked fifth inthe 10leading causes of death and fifth inthe 10 leading causes of illness, with an incidence...
... categorized the TB lesion of each subject as mini-mal, moderately advanced, or far-advanced, based on the clas-sication ofthe National Tuberculosis and Respiratory Disease Association of ... require three or more acceptable curves for an adequate test, this is not practical for a large-scale exami-nation survey, so we analyzed only the data of subjects with two or more acceptable spirometry ... 2001 by the Korea Institute for Health and So-cial A airs. Based on the 2000 Population Census ofthe Nation-al Statistical Oce of Korea, a stratied, multi-stage, clustered, probability...
... Financial Sector Deepening Trusts in Kenya and TanzaniaGHAMFIN Ghana Microfinance Institutions NetworkILO International Labour OrganisationINAFI International Network of Alternative Financial ... List of AbbreviAtions3ie International Initiative for Impact EvaluationAEMI Association of Ethiopian Microfinance InstitutionsAFMIN African Microfinance NetworkAIMS Assessing the Impact of ... studies included inthe in- depth synthesis 85Appendix 4.2: Narrative synthesis of findings relating to the impact of microfinance on the wealth ofthe poor 89Appendix 4.3: Narrative synthesis of...
... concentrations of PD98059 (MEK1 inhibitor) and G F109203X (proteinkinase C inhibitor) indicating that each of these pathwayshas a modulatory r ather thana mandatory role to play in mediating the ... that activation of P tdIns 3-kinase isthe key regulatory step inthe proliferative p athwayand that each ofthe other pathways interacts with thispathway with the magnitude ofthe cellular ... was thenseparated a nd quantified by thin layer chromatographyusing a solvent system containing chloroform/methanol/ammonia /water (20 : 15 : 3 : 5, v/v/v/v) and autoradiog-raphy;32P incorporation...
... Ala-Ala-Val-Ala-pNA or Ala-Pro-pNA, exhibiting precisely the sequence of FRAP-TGase.Yellowing ofthe Ala-Ala-Val-Ala-pNA solution must be the result of direct cleavage ofthe anilide bond. Ala-pNAand ... aminopeptidase is therefore logical. However, a side reaction with the tetrapeptide Ala-Ala-Val-Ala-pNA was revealed. The inability ofthe peptidase to hydrolyse Ala-Ala-pNA andAla-pNA (or other chromogenic ... distinct differ-entiation stages. Culture on agar plates containing glucose,yeast and malt extracts allows the organism to developsubstrate and aerial mycelia culminating inthe formation of spores...
... microsatel-lite is also related to inflammatory diseases such as atopy[28], asthma [29], and rheumatoid arthritis [15]. Finally, the correlation ofthe -173 C allele and the -794 CATT7allele as ... calculations,coordinated the study and drafted the manuscript. Allauthors read and approved the final manuscriptAcknowledgements The authors would like to thank Sabine Mering for expert technical assist-ance ... for single marker analysis. Statistical significancewas assumed at p < 0.05. Statistical power (1-β) was calcu-lated using binominal power calculation. The power cal-culation for the -173...
... report the number of falls inthe past year.Data AnalysisPrior to data analyses the gait variability data were exam-ined for normality. The gait variability data were relativelynormally distributed ... analyzed the data, and drafted the manuscript. JEB participated inthe data analyses andmanuscript preparation. JVS participated inthe design of the study, data analyses, and writing the manuscript. ... be at risk for falls by their gait speed (i.e. those walking at a near normal gait speed) variability of step width may provide valuable information about fallrisk. In people walking at a near...