the sorbent layer is protected by a 0 25 mm thick sheet of teflon that prevents any contact between the sorbent layer and the metal die blocks there is a lip on the teflon that extends past the
Báo cáo khoa học: Expression of the Drosophila melanogaster ATP synthase a subunit gene is regulated by a transcriptional element containing GAF and Adf-1 binding sites pptx
... characterization of the promoter regions of mammalian nuclear-encoded mitochondrial genes, and has led to the identification of several transcription factors and coactivators that regulate the expression ... downstream of transcriptional initiation sites in Drosophila promoters include ACGT, ACAA, ACAG, and AACA [32], and these were detected at )17, )18, )36 and ) 103 positions of the a- F1-ATPase gene ... confirmed that they corresponded to cDNAs originated by the alternative selection of polyadenylation signals located at position 101 and 462 downstream of the TAA translation stop codon (Fig 6C) Northern...
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Báo cáo khoa học: The activity of Plasmodium falciparum arginase is mediated by a novel inter-monomer salt-bridge between Glu295–Arg404 doc
... [17] Agmatine is formed by decarboxylation of arginine (arginine decarboxylase) and is converted by agmatinase to putrescine and urea Arginase is thus part of one of two alternative biosynthetic ... enzymes: a promising approach to therapy of African sleeping sickness, Chagas’ disease, and leishmaniasis Amino Acids 33, 359–366 12 Wallace HM ( 200 7) Targeting polyamine metabolism: a viable therapeutic ... trimeric conformation partially retained The Km value for the Glu295 Ala mutant was not measurable because it was not saturated up to 200 mm arginine Mutating Arg 404 to Ala abolished trimer formation...
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Báo cáo khoa học: Activated transglutaminase from Streptomyces mobaraensis is processed by a tripeptidyl aminopeptidase in the final step pptx
... Ala-Phe-Pro-pNA Ala-Ala-Ala-pNA Pro-Leu-Gly-pNA Ala-Ala-Phe-pNA Suc-Ala-Ala-Phe-pNA Val-Leu-Lys-pNA Cbz-Pro-Phe-Arg-pNA Ala-Ala-Val-Ala-pNA Ala-Ala-Pro-Leu-pNA Suc-Ala-Ala-Pro-Phe-pNA
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Báo cáo y học: "Nociceptive tolerance is improved by bradykinin receptor B1 antagonism and joint morphology is protected by both endothelin type A and bradykinin receptor B1 antagonism in a surgical model of osteoarthritis" pdf
... (0. 002 0 ≤ P ≤ 0. 0214, one-way ANOVA with Holm post-hoc) MR analysis of knee joints revealed that antagonist-treated animals had greater To investigate the effects of ETA and/ or BKB1 antagonist ... observed in the dual-antagonist-treated animals than in the single-antagonist-treated animals Radiological scoring of the DX views for a panel of OA joint degenerative changes (Table and Additional file ... voxel size of 156 .25 × 156 .25 × 100 0 μm 16 different TE were used: 10, 20, 30, 40, 50, 60, 70, 80, 90, 100 , 1 10, 1 20, 1 30, 1 40, 1 50, and 1 60 ms Kaufman et al Arthritis Research & Therapy 201 1, 13:R76...
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Báo cáo khoa học: PCSK9 is phosphorylated by a Golgi casein kinase-like kinase ex vivo and circulates as a phosphoprotein in humans doc
... 1 100 0 12 500 SO42– 10 10 1 100 0 12 500 1 100 0 12 500 1 200 0 1 400 0 1 200 0 1 400 0 1 200 0 Mass/charge (m/z) 1 400 0 1 200 0 1 400 0 SO42– 13827.9 Da (13835.5 Da) 13782.9 Da (13777.5 Da) 13775.1 Da (13777.5 Da) ... 11782.8+H 25 sulfated PO42– SO42– 75 50 phosphorylated 13875 .0 Da (13871.5 Da) ACS 10 D50E H PO42– 2– 0 1 100 0 12 500 1 100 0 12 500 0 1 100 0 12 500 1 200 0 1 400 0 SO42– ACS 10 1 200 0 1 200 0 1 400 0 1 400 0 Mass/charge ... phosphorylation in the propeptide of PCSK9 B 409 3.4 + H PCSK9-V5 + trypsin + SAP 20 10 400 0 ns 1 404 5.9 + H 405 0 4 100 41 50 4 200 42 50 1 200 0 Mass/charge (m/z) 1 300 0 1 400 0 1 500 0 1 600 0 Mass/charge (m/z)...
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Báo cáo khóa học: Emerin binding to Btf, a death-promoting transcriptional repressor, is disrupted by a missense mutation that causes Emery–Dreifuss muscular dystrophy pdf
... 207 214 45AAA 45EEE 104 AYGEAEA 122AA 145AA 151AA 161AAA 175AAA 192ASAAA 198AAAAA 206 AAPA 24AAAA 34AAAA 54F 70AAAMA 76APAKADAA 112AASRAVAAAVA 133H 141AASAEECKAA 164AAHARPA 179AA 183H 196AA 207 AA ... CAC GAG AAA AGT CTA CCT TC AAC ATA TGA TCA CGC ACT ACC GCC C TCC ATA TGC TAG AAG GGG TTG CCT GGC GGA TCC CTA GAA GGG GTT GCC TTC TTC GGG GAT CCC TGG CCC CAG AGC GG TTG GAT CCT TAT GTA CTA GCA ... ATA TGG ACA ACT ACG CAG ATC CGT GGA TCC TCA TGA CTT ATG GGG AGC CCG A 377–5¢ 521–5¢ 574–3¢ 646–3¢ 761–3¢ end-3¢ emerin DNA sequence of the primer AAC ATA TGG ATC AGG AAG CTC TAG ATT AC AAC ATA...
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Báo cáo khoa học: Transcription of mammalian cytochrome c oxidase subunit IV-2 is controlled by a novel conserved oxygen responsive element pptx
... GCTGAAGACCGCGGAGGTAC GAGGTACCCAGAACTGCCCTG GATAGTCAGTGGGGGAAACCTCAG CAGCAAAAGAGGGCTGTGTGGTG TGGCCGCCACGAACATCCCATC GTTGCCCAGGTTGGAGTGCAG CTCGCGGGCTCGGCAGTGGGAG AGTCTATTCTCGAGCACCTGGGACTACAGG AGTCTATTCTCGAGCCCAAAGCGCTGAGATTACAG ... AGTCTATTCTCGAGCCCAAAGCGCTGAGATTACAG AGTCTATTCTCGAGATGCTTCTGGAGTAGGAGGCA AGTCTATTCTCGAGGTGTGGAGGAGGCAGGGAGAC AGTCTATTCTCGAGGAGGCGCTCTGCAGTGCCTC AGTCTATTCTCGAGAAGCAGGACGTTCCCACGCTG AGTCTATTCTCGAGGGGGCGGGCGCCCGCACTCAG ... USA) Quantification of EMSA bands After the gels had been scanned as described above, the intensities of individual bands were analysed with imagequant software (version 5, Molecular Dynamics) and...
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Báo cáo y học: "Protease inhibitor-induced nausea and vomiting is attenuated by a peripherally acting, opioid-receptor antagonist in a rat model" doc
... collection and assembly of data, analysis and interpretation of the data, critical revision of the article, and final approval of the article SRM was responsible for the analysis and interpretation of ... the data, and critical revision of the article HHA was responsible for the collection and assembly of data, and analysis and interpretation of the data AF was responsible for the collection and ... methylnaltrexone and naltrexone in plasma samples (A) , a chromatogram of a standard plasma extract of methylnaltrexone ( 100 .0 ng/mL) and naltrexone ( 50. 0 ng/mL); (B), 92.5 ng/mL methylnaltrexone was...
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Báo cáo y học: "Sensitivity of mice to lipopolysaccharide is increased by a high saturated fat and cholesterol diet" pptx
... increased plasma SAA as seen by others [ 20] , and plasma CD14 was induced (Figure 8A) L-alanine:2-oxoglutarate aminotransferase, ALT Although the consequences of the increases in SAA and CD14 by ... 557:3 10- 5; discussion 315-6 Shimada H, Hasegawa N, Koh H, Tasaka S, Shimizu M, Yamada W, Nishimura T, Amakawa K, Kohno M, Sawafuji M, Nakamura K, Fujishima S, Yamaguchi K, Ishizaka A: Effects of ... VCAM-1 and iNOS promoters are activated by AP-1, NFkB, and by STAT1 and its secondary target, interferon regulatory factor-1 [12-14,44] TNFα is a strong activator of AP-1 and NFkB, and IL-6 and...
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Báo cáo Y học: Mechanism of 1,4-dehydrogenation catalyzed by a fatty acid (1,4)-desaturase of Calendula officinalis pptx
... analysis of yeast lipids was performed using a Fisons VG TRIO 200 0 mass spectrometer (VG Analytical, UK) controlled by Masslynx version 2 .0 software, coupled to a GC 800 0 Series gas chromatograph as ... 11(Z)- tetradecenoate to 10( E),12(E)-tetradecadienoate by initial H-abstraction at C 10 and 11(E)-tetradecenoate to 9(Z),11(E)-tetradecadienoate by initial oxidative attack at C9 [39] Whether these ... reaction has been determined to be at the carbon furthest from C-1 In contrast, all other desaturase-catalyzed oxidations studied to date are initiated at the carbon closest to the acyl headgroup...
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measurement and comparison of credit risk by a markov chain an empirical investigation of bank loans in taiwan
... 0. 037 0. 008 0. 006 0. 005 0. 003 0. 007 0. 006 0. 007 0. 0 10 0 .03 8 0. 009 0. 013 0. 011 0. 016 0. 013 0. 0 20 0 .01 4 0. 028 0. 061 0. 034 0. 049 0. 044 0. 047 0. 058 0. 063 0. 079 0. 094 0. 055 0. 031 0. 043 0. 037 0. 039 0. 049 ... 0. 005 0. 012 0. 017 0. 014 0. 0 30 0 .04 0 0. 012 0. 016 0. 011 0. 005 0. 013 0. 019 0. 022 0. 021 0. 037 0. 014 0. 015 0. 012 0. 006 0. 013 0. 018 0. 018 0. 022 0. 038 0. 014 0. 014 0. 0 10 0 .01 2 0. 016 0. 022 0. 021 0. 018 0. 037 ... 0. 049 0. 052 0. 068 0. 081 0. 053 0. 026 0. 032 0. 031 0. 033 0. 042 0. 043 0. 058 0. 067 0. 049 0. 023 0. 026 0. 026 0. 027 0. 0 30 0 .03 5 0. 041 0. 048 0. 044 0. 0 20 0 .01 9 0. 017 0. 019 0. 019 0. 028 0. 028 0. 033 0. 0 40 0 .01 2...
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Báo cáo y học: " Increased production of viral proteins by a 3''''-LTR-deleted infectious clone of human T-cell leukemia virus type 1" ppsx
... viral expression patterns (A) Diagram of the molecular clones showing the deletion series of the 3' LTR and the deletion of the reverse TATA box of the 3' LTR (B) The amount of p19 gag in the ... cellular factors that inhibit the expression of the tax gene between 40 nt and 113 nt at the AatII site downstream from the beginning of the 3' LTR Recently, Fryrear et al reported that a Tax mutant ... expression of other HTLV-1 genes (gag, pol, and env) was the same as that of the tax gene (data not shown) The Δreverse TATA mutant did not produce the viral antigen Recently, the expression of the HTLV-1...
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Báo cáo y học: " Exploring the black box of quality improvement collaboratives: modelling relations between conditions, applied changes and outcomes" ppsx
... Estimate (SE) 0. 69 (0. 08)c 0. 00 (0. 00) 0. 15 (0. 07 )a Estimate (SE) 0. 86 (0. 11)c 0. 07 (0. 06) 0. 06 (0. 05) Estimate (SE) 0. 75 (0. 08)c 0. 03 (0. 04) 0. 08 (0. 06) Estimate (SE) 2 .01 (0. 29)c 0. 42 (0. 23)b 0. 04 ... variance at each level are shown Hypothesis A concerns the relation between the three conditions and the number of changes teams applied The association between organisational support and external ... collaborative is aimed at organisational development and the dissemination of healthcare innovations [ 10] It is the third pillar of 'Better Faster', a programme embedded in a broader national...
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báo cáo khoa học: " Exploring the black box of quality improvement collaboratives: modelling relations between conditions, applied changes and outcomes" doc
... Estimate (SE) 0. 69 (0. 08)c 0. 00 (0. 00) 0. 15 (0. 07 )a Estimate (SE) 0. 86 (0. 11)c 0. 07 (0. 06) 0. 06 (0. 05) Estimate (SE) 0. 75 (0. 08)c 0. 03 (0. 04) 0. 08 (0. 06) Estimate (SE) 2 .01 (0. 29)c 0. 42 (0. 23)b 0. 04 ... variance at each level are shown Hypothesis A concerns the relation between the three conditions and the number of changes teams applied The association between organisational support and external ... collaborative is aimed at organisational development and the dissemination of healthcare innovations [ 10] It is the third pillar of 'Better Faster', a programme embedded in a broader national...
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Báo cáo y học: " A computational model for functional mapping of genes that regulate intra-cellular circadian rhythms" pps
... 0. 0 10( 0 .00 1) 0. 095 (0. 002 ) 0. 102 (0. 005 ) 0. 201 (0. 006 ) 0. 309 (0. 011) 0. 200 0. 204 (0. 011) 0. 037 0. 038 (0. 002 ) δx δy ρ Genetic Parameters Given MLE p q D 0. 6 0. 6 0. 08 0. 601 (0. 002 ) 0. 67 (0. 091) 0. 067 (0. 022) ... 0. 17 (0. 003 ) 1. 70 2. 80 0. 90 0. 40 0.18 0. 18 1.71 (0. 0 60) 2. 80( 0 .02 0) 0. 93 (0. 066) 0. 40( 0 .00 1) 0. 18 (0. 005 ) 0. 18 (0. 001 ) Matrix Structuring Parameters Given MLE φx φy ψx ψy 0. 0 10 -0. 100 0. 100 -0. 200 0. 307 ... 1. 50 3 .00 1. 10 0. 30 0.16 0. 16 1.52 (0. 059) 3 .02 (0. 015) 1.14 (0. 052) 0. 30( 0 .00 9) 0. 16 (0. 003 ) 0. 16 (0. 004 ) 1. 40 2. 90 1. 30 0.35 0. 17 0. 17 1.42 (0. 006 ) 2. 90( 0 .00 9) 1.34 (0. 028) 0. 35 (0. 002 ) 0. 17 (0. 011) 0. 17 (0. 003 )...
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Tài liệu Báo cáo Y học: Thermostability of manganese- and iron-superoxide dismutases from Escherichia coli is determined by the characteristic position of a glutamine residue pdf
... 1 .06 0. 80 0.83 Manganese Ratioa 0. 07 0. 02 0. 05 0. 16 16 49 15 Manganese superoxide dismutase mutants Mn[wt] 0. 03 0. 71 Mn[G77Q] 0. 04 0. 39 Mn[Q14 6A] 0. 00 0. 50 Mn[G77Q/Q14 6A] 0. 23 0. 87 23 10 100 a ... 1–2 h and used to inoculate 50 mL of 2TY media containing 100 lgÆmL)1 ampicillin, 50 lM ferric sulfate, 50 lM manganese sulfate, 2 50 lM paraquat and 0. 1 mM IPTG to an initial D 600 of 0. 03 Cultures ... mutagenesis reactions together with oligonucleotides ECF-Q69G d(5¢-AACAACGCAGCTGGGCTCTG GAACCAT), ECF -A1 41Q d(5¢-TCAACCTCTAACCAG GCTACTCCGCTG) ECM-G77Q d(5¢-AACAACGCTGG CCAGCACGCTAACCAC) and ECM-Q146A...
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Báo cáo khoa học: In vitro gamma-secretase cleavage of the Alzheimer’s amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc potx
... Lane 2, lysate sample alone Note that a separation between c-3FLAG standard and e-CTF-3FLAG was achieved in lane An uncharacterized anti-FLAG immunoreactive protein migrating between the a and ... fractions This shows that E coli and mammalian cells have different mechanisms to control the aggregation states of these substrates and supports our original hypothesis that mammalian cellular ... encoding 3FLAG-tagged APP-CTFs mimicking products from cleavage at position 40 (gamma-3FLAG standard) and 49 (epsilon-3FLAG standard) were also made to aid in the identification of 3FLAG-tagged CTFs...
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Báo cáo khoa học: In vivo degradation of nitric oxide synthase (NOS) and heat shock protein 90 (HSP90) by calpain is modulated by the formation of a NOS–HSP90 heterocomplex pot
... intracellular Ca2+ concentration ([Ca2+]i) by the administration of a high-sodium diet (HSD) [28], and studied calpain degradation of NOS and HSP 90 in brain and aorta To amplify the range of fluctuations ... degradation of NOS and HSP 90 by calpain M Averna et al Table Levels of native and 15 kDa calpastatin species in brain and aorta of NMS and HMS rats treated with HSD for weeks The data reported are ... bands FEBS Journal 275 ( 200 8) 2 501 251 1 ª 200 8 The Authors Journal compilation ª 200 8 FEBS 2 507 In vivo degradation of NOS and HSP 90 by calpain M Averna et al Fig Identification of NOS–HSP 90 association...
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Báo cáo khoa học: Induction of PAI-1 expression by tumor necrosis factor a in endothelial cells is mediated by its responsive element located in the 4G/5G site ppt
... Journal 272 ( 200 5) 5821–5831 ª 200 5 The Authors Journal Compilation ª 200 5 FEBS The 4G ⁄ 5G site and PAI-1 expression M Swiatkowska et al B A TNFα H2O2 [µΜ] NAC 100 200 100 200 100 200 100 200 C ... of TNFa and H2O2 on PAI-1 expression in vascular endothelial cells Expression of PAI-1 was analyzed at the level of protein synthesis (A) in the presence or absence of NAC ( 10 mM) The PAI-1 antigen ... of TNFa ( 50 ngÆmL)1) on intracellular oxidation analyzed by DCF fluorescence in vascular endothelial cells with and without of NAC ( 10 mM) (C) The effect of PEG and PEGcatalase on endothelial cells...
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Tìm thêm: xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng 9 tr 25