the role of newton in the development of calculus
Báo cáo khoa học: "The key role of semantics in the development of large-scale grammars of natural language" pdf
... results in trimming the dry branches off the bush. And this is what the semantic type in (16) captures.3.3 Impingement Predicates In order to capture the semantic properties of the arguments of the ... (SOA [ch -of- loc-relFIG ElThat is, as (16) above captures, in German trim-ming necessarily results in trimming somethingoff something else; in the case of example (9)above trimming the bush ... representative verb of the impingement predicates class in German, the verbschlagen (hit) in examples (10)-(12) above, wepropose the semantic types in (17) and (18), whichare in the spirit of the MRS-based...
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Tài liệu Improving health, connecting people: the role of ICTs in the health sector of developing countries ppt
... specific to the use of ICTs in the health sector in developing countries. A summary of these key lessons as they relate to intermediaries and beneficiaries, to improving the functioning of health ... • the use of telemedicine to improve diagnosis and enhance patient care • improvements in the continuing professional development of health workers and better sharing of research findings ... understanding and the evidence base about the use of ICTs in the health sector are: • How to evaluate the impact of the use of ICTs on health? • What can be done to strengthen the role of and...
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Tài liệu The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States: A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory Committee on Immunization Practices docx
... (39 ). The renewed interest in examining the indications for BCG vaccination in the United States included consideration of the wide range of vaccine efficacies deter-mined by clinical trials ... toexplore the sources of the heterogeneity in the efficacy of the BCG vaccine reported in the individual studies. Using a model that included the geographic latitude of the study site and the data ... <5 mm indurationafter skin testing with 5 TU of PPD tuberculin. The Tice strain of BCG is administeredpercutaneously; 0.3 mL of the reconstituted vaccine is usually placed on the skin in the lower...
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Tài liệu Báo cáo khoa học: The role of antioxidants in the cytotoxicity of chemotherapeutic drugs pptx
... undergoes fusion with the membrane of intra-endosomal vesicles contained within MVBs,thereby releasing the nucleocapsid into the lumen of these vesi-cles. Then, the capsid uses these intra-endosomal ... and milddevelopmental delay. The protein defective in this disorder is alsoa NHEJ protein. The distinct clinical features of the patients willbe discussed in the context of the protein function.3.4 ... Mutations in the ERCC1 gene induce a distinct set of accelerated ageing features,with a rate of onset depending on the severity of the mutation. The correlation between repair defect severity and clinical...
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Tài liệu Báo cáo khoa học: A possible role of mitochondria in the apoptotic-like programmed nuclear death of Tetrahymena thermophila Takashi Kobayashi and Hiroshi Endoh docx
... which appear to be involved in the finalresorption of the parental macronucleus during PND in T. thermophila, and suggested the involvement of mitochondria in this process [19]. In mammalian apop-tosis, ... key role in PND in Tetrahymena. Unfortunately, the involvement of mito-chondria in PND has not been clarified fully. To eluci-date the role of the mitochondrion as a key effectorwe studied the ... directlyshow the localization of mitochondria in the autophag-osome, as the red fluorescence corresponding to intactmitochondria was not observed in the area. Therefore,to confirm further the localization,...
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Tài liệu Báo cáo Y học: Role of electrostatics in the interaction between plastocyanin and photosystem I of the cyanobacterium Phormidium laminosum ppt
... go in the same direction. The inverse isthecasefortheattractioninthecaseofAnabaena. Also, if the structure of the final complex in which electron transfertakes place remained unaltered with increasing ... character-ization of the plastocyanins has been described [1].Representations of the electrostatic surfaces showing the changes introduced by the mutations are displayed in Fig. 1. The decay of the flash-induced ... interaction.Electron-transfer chains like that of oxygenic photosyn-thesis impose special restraints on the proteins involved.Reactions must be fast to allow rapid turnover of the chain. Binding between the reaction...
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Tài liệu The Development of the Feeling for Nature in the Middle Ages and Modern Times doc
... 'all the present of earth vanished into the future of Heaven, and the Kingdom of the Infinite arose upon the ruins of the finite.' The beauty of earth was looked upon as an enchantment of the ... thorn.Delight in summer, complaint of winter this is the fundamental chord struck again and again; there isscarcely any trace of blending the feelings of the lover with those of Nature. It is ... and the howling of wind, the rustle of leaves, the soughing in the tree tops, weresounds of their presence. The worship of woods lasted far into Christian times, especially among the Saxonsand...
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Role of Corticosteroids in the Treatment of Tuberculosis: An Evidence-based Update potx
... imaging of the brain was also performed in a subset of patients in this study.36 It was found that use of corticosteroidspossibly reduced the risk of developinghydrocephalus and vasculitic infarcts; ... of opportunistic infections in HIV-infected adults andadolescents: recommendations from CDC, the NationalInstitutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. ... Vietnam. Following the publication of this trial, Prasad and Singh12 updatedtheir Cochrane systematic review on the efficacy of corticosteroids in TBM.12 The combined mortality in the control...
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Báo cáo khoa học: The role of helix 8 and of the cytosolic C-termini in the internalization and signal transduction of B1 and B2 bradykinin receptors potx
... by the amount of internalized agonist[20]. As the internalization is expressed in percentage of total binding, decreasing the binding affinity of the Role of helix 8 and C-termini in bradykinin ... com-prising putative helix 8, may be involved in the inter-action of GPCRs with cognate G proteins.Synthetic peptides from the C-terminus of the Gasubunit Gtand of the Gc subunit of transducin ... addition of scintillation fluid. Nonspecific bindingwas determined in the presence of 5 lm unlabeled agonistand subtracted from the total binding to calculate the spe-cific binding.Internalization of...
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The Role of Probiotics in the Poultry Industry doc
... stomach, the presence of bile acids in the intestines, and the competition against other micro-organisms in the gastro-intestinal tract [91,92]. The tentative ways for selection of probiotics ... cytokines, such as IL-4 and IL-10, are induced by lactobacilli [84-85,88]. The outcome of the production of Th2 cytokines is the development of B cells and the immunoglobulin isotype switching ... colonizing the intestine may secrete the enzyme, thus increasing the intestinal amylase activity [82,83]. It is well established that probiotics alter gastrointestinal pH and flora to favor an increased...
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Báo cáo khoa học: The role of the Fe-S cluster in the sensory domain of nitrogenase transcriptional activator VnfA from Azotobacter vinelandii potx
... by Austinet al. [22]. In their study, the N-terminal domain of AnfA was truncated to prevent the intrinsic aggrega-tion of the intact form during purification. The obtained variant retained transcriptional ... potential ligands of the Fe-S cluster. Consequently, the binding of the ATPanalog and the subsequent rearrangement of the inter-domain interaction affects the electronic condition of the Fe-S cluster ... may reside in the GAFdomain and the environmental factors affecting AnfAactivity remain unknown because of the absence of the N-terminal domain in this variant. Because sensing is aprincipal...
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Báo cáo khoa học: New evidence for the role of calcium in the glycosidase reaction of GH43 arabinanases pot
... distribution of BsArb43B in the proximity of the active site. Arabinotriose in the binding cleft is representedusing sticks. (B) Detailed view of the binding cleft with arabinotri-ose. (C) Details of the ... witharabinohexose [15], this loop makes the reducing end of the carbohydrate chain bend towards the solvent,probably optimizing binding of the carbohydrate chain in the cleft, and resulting in trioses ... for the optimal activity of BsArb43B.Furthermore, to determine whether the role of the calcium is structural, thermal shift assays were per-formed to determine the Tm of the protein in the...
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Báo cáo khoa học: Zinc-binding property of the major yolk protein in the sea urchin ) implications of its role as a zinc transporter for gametogenesis ppt
... contrast, part of the incorporated CFMYP is not processed toEGMYP, enabling it to retain zinc. Indeed, 33% of the total zinc in the ovary at stage 1 and 13% of the total zinc in the testis at ... determined by ICP-AES. To investigate the accumulation of zinc in the gonads during gameto-genesis, increases in the size of the gonads during this periodwere taken into consideration. Thus, zinc ... of the zinc peaks was coincident with the MYPpeak in both the ovary and the testis, indicating thatpart of the zinc in the immature gonads is bound toMYP. The elution patterns of zinc were...
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Báo cáo khoa học: Isothermal unfolding studies on the apo and holo forms of Plasmodium falciparum acyl carrier protein Role of the 4¢-phosphopantetheine group in the stability of the holo form of Plasmodium falciparum acyl carrier protein docx
... FEBS 3325Isothermal unfolding studies on the apo and holo forms of Plasmodium falciparum acyl carrier protein Role of the 4¢-phosphopantetheine group in the stability of the holoform of Plasmodium ... thrombin cleavage site was engineered in the pET28a vector immediately after the N-terminal His-tag. The N-terminus His-tag of ACP was cleaved by the addition of 1 U of thrombin from bovine plasma ... obtain DGH2O, the free energy of unfolding in water at temperature T. In the first method, a single guanidine hydrochloride-induced denaturation, where the observed CD signal ateach point in the...
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Báo cáo khoa học: Dual role of Nbs1 in the ataxia telangiectasia mutateddependent DNA damage response ppt
... formation of MRNfoci [19–21]. The Mre11-binding domain of human Nbs1 hasbeen localized to amino acids 682–693 in the COOH-terminal region of the protein. Deletion of this region of Nbs1 results in ... damage, thereby promotingATM-dependent signaling [23]. Domains similar to the ATM-binding domain of Nbs1 are also found in ATRIP and Ku80 and are required for the interaction of these proteins with ... an NH2-terminally truncatedNbs1 protein that contains an intact Mre11-bindingdomain. Differences in the nature of the Nbs1 muta-tion, as well as in the dose of radiation administeredto...
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