the role of new antithrombotic drugs
Tài liệu Báo cáo khoa học: The role of antioxidants in the cytotoxicity of chemotherapeutic drugs pptx
... undergoes fusion with the membrane of intra-endosomal vesicles contained within MVBs, thereby releasing the nucleocapsid into the lumen of these vesicles Then, the capsid uses these intra-endosomal ... are therefore grouped under the name of ‘alpha-synucleinopathies’ The mechanism of alpha-syn aggrega- tion in PD and DLB is not yet clear The presence of ubiquitin in LBs and the association of ... S3.2-1 The role of the human mismatch repair system in the processing of modified nucleotides N Mojas, F Fischer, M Lopes, P Cejka and J Jiricny Institute of Molecular Cancer Research, University of...
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Báo cáo khoa học: New evidence for the role of calcium in the glycosidase reaction of GH43 arabinanases pot
... Together, these results confirm that the atom in the cluster is calcium To determine whether the calcium ion has a specific role in the activity of BsArb43B, assays were performed in the presence of ... in the absence of chelators (90.94 ± 7.85 UÆmg)1) These results suggest that the presence of calcium is important for the optimal activity of BsArb43B Furthermore, to determine whether the role ... that the presence of the C-terminal domain is crucial for the acquisition of the correct enzyme fold Analysis of the interactions between the two domains led us to presume that expression of the...
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Báo cáo Y học: The role of zinc in the methylation of the coenzyme M thiol group in methanol:coenzyme M methyltransferase from Methanosarcina barkeri New insights from X-ray absorption spectroscopy doc
... interpret these results as indicating the binding of the thiol sulfur of HS-CoM to the zinc atom of MtaA in a way that it replaces one of the nonsulfur ligands, possibly the oxygen of coordinated ... atoms ligated to the zinc of MtaA increases upon formation of the MtaAcoenzyme M complex explainable by ligation of the thiol sulfur of coenzyme M to the active-site zinc We simulated the experimental ... further details see gure captions The ễedge energyế used to describe the position of the absorption edge is the energy value corresponding to 0.65 units of normalized absorption (The value of...
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Báo cáo y học: "Targeting MDM2 by the small molecule RITA: towards the development of new multi-target drugs against cancer" potx
... behavior observed by these compounds would compensate their therapeutic deficiencies because of the dynamic nature of the targets involved and the observed promiscuity of MDM2 over p53 Thereby, RITA ... of docking ∆Gb (kcal/mol) Kd (µmol) focc Ntot Blind Fine -6.36 -6.32 22 23.3 50 93 ture of RITA and to improve the activity of a new family of potent anti-cancer drugs Conclusion The aim of the ... allows the entire surface of the target to be searched efficiently The grid maps representing the protein were calculated with the aid of AutoGrid, a utility of the AutoDock software Two different...
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Ready, steady, grow the role of the CFO in seizing new opportunities
... net new investment business in 2013—is one of the “jewels in our crown” and there are plans to double the size of its managed funds in the US over the next five years, says Mr Keers Still, the ... substantial project.” Providing a higher degree of transparency around the performance of the business is a theme that Mr Rennison highlights, too “As the leader of the finance community in a large organisation, ... rather than the rule The fact that the Schroders family still owns 46% of the business helps the board to take a longer-term view, while being a FTSE 100 public company also ensures that the governance...
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Primate Conservation in the New Millennium: The Role of Scientists
... permitting the formulation of hypotheses to account for inter-site differences, there are other benefits of such explicit comparisons First, they allow the researcher to test the generality of the results ... permit them to test the hypothesis that the nature of the matrix in which the fragments are found is important in determining the use of fragments by primates, as has been documented for other ... the probable magnitude of the exploitation can be considered in light of the population density, the percent of the population that is rural, and the amount of forest that the rural population...
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Economics letters volume 107 issue 2 2010 doi 10 1016%2fj econlet 2010 01 027 w n w azman saini; siong hook law; abd halim ahmad FDI and economic growth new evidence on the role of financial ma
... mediating the impact of FDI on growth, using data from 91 countries over the period 1975–2005 One major contribution of the paper is the adoption of the regression model based on the concept of threshold ... particularly well suited to capture the presence of contingency effects and to offer a rich way of modelling the influence of financial markets on the dynamics of FDI and growth is the following threshold ... ratio of commercial bank assets to commercial bank plus central bank assets The final measure is the liquid liabilities of the financial system (henceforth, LLY) It measures the overall size of the...
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The Role of Power
... who are truthful and demonstrate regard for their own outcomes and those of others • Moderately Politicized Area – greater acceptance of behind the scenes tactics so long as the goals of the group are achieved ... Outline Role of Power Rules for Using Power Role of Power Power defined: • Ability or official capacity to exercise control; authority • Ability to influence or control others Sources of Power ... Find the Soft Spot Encourage others to open up • Gain disclosure of something private or personal about your counterpart • Expression of trust Identify true motivations and sources of objections...
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Circuit theory of finance and the role of incentives in financial sector reform
... DC: The World Bank) Chernow, Ron, 1997, The Death of the Banker The Decline and the Fall of the Great Financial Dynasties The Triumph of the Small Investor (New York: Vintage Books, a Division of ... to further improve the bank’ risk position s and counterparties, on their side, might consider for them unnecessary to further assess the riskiness of the bank Finally, the inadequacy of the static ... factoring the long-term market potential of borrowing firms in their risk analysis The higher their reputational capital, the stronger their incentive to lengthen the time horizon of their approach...
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Facts of Vietnam Freight forwarding industry and the role of Vietnam Freight Forwarders Association (VIFFAS) to the industry in international economic integration processhelpful to Oristar.doc
... such professional colleagues on the world The Association has the role of coordinating the activities of the members in order to protect the interests of the members and improve the position of Vietnam ... to the realization of the objectives and duties of the Association, may be invited to join the Association as Honorary members In general, this stipulation on the membership in the Statue of the ... expanding With their experiences, they have learned the value of offering quality services In the way of growing, they have also open branches to establish a worldwide presence These companies...
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Báo cáo y học: "Human toxoplasmosis and the role of veterinary clinicians"
... where the consequences of infection can be very severe, while the risk of living with one’s beloved cat is practically nill References Angulo FJ, Glaser CA, Juranek DD et al Caring for pets of immunocompromised ... with the human immunodeficiency virus Clin Infect Dis.1994;18:14-24 Han K, Shin DW, Lee TY, et al Seroprevalence of Toxoplasma gondii infection and risk factors associated with seropositivity of ... 94: 963-965 Grant S and Olsen CW Preventing zoonotic diseases in immunocompromised persons: the role of physicians and veterinarians Emerg Infect Dis 1999; 5: 159-163 http://www.medsci.org ...
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The role of language in adult education and poverty reduction in Botswan
... improve the quality of life of the poor and rural people adult education programs should include as one of its components the observation and imitation of the artisans and other skilled persons in the ... for the betterment of their conditions It could mobilize the so called minorities to oppose their status and challenge the hegemony of the majority communities in Botswana 31 In most parts of the ... maintains the hegemony and the gap between the poor and the rich, the major and minority groups In order to redress poverty the adult education program needs to be aware of the social functions of language...
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153 The role of marketing activities to bankcard and actual state of Ngân hàng nông nghiệp và phát triển nông thôn (AgriBank) cards
... sells the transaction to the acquire and is reimbursed the amount of the sales ticket by the acquirer (4) - The acquirer then summits the ticket to the issuer for payment, via the ICO interchange ... system 9 (5) - The issuer bills the cardholder (6) - Finally, the cardholder repays the issuer for the goods or services originally purchased from the merchant ICO are at the centre of the transaction ... maintaining the flow of funds and information between issuing and acquiring members The exchange of financial information is called clearing The exchange of the actual funds for the transaction and the...
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494 The role of marketing activities to bankcard and actual state of Ngân hàng nông nghiệp và phát triển nông thôn (AgriBank) cards
... “bộ” “trọn gói” theo nguyên tắc giá gói nhỏ tổng số tiền mua hàng theo phương thức riêng rẽ Định giá theo nguyên tắc địa lý: cách thức mà doanhnghiệp định giá bán sản phẩm theo nguyên tắc địa ... sản phẩm Bề rộng chủng loại sản phẩm phân giải số lượng mặt hàng thành phần theo tiêu thức định ví dụ theo kích cỡ, theo công suất… Bề rộng chủng loại sản phẩm mục tiêu công ty định phần Những ... trường theo giác độ khác Theo quan điểm Marketing thị trường bao gồm tất khách hàng tiềm ẩn có nhu cầu mong muốn cụ thể sẵn sàng có khả tham gia vào trao đổi để thoả mãn nhu cầu Như vậy, theo khái...
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The role of advertising in society
... values, others say advertising merely reflects the values of society rather than shaping them They argue that consumers' values are defined by the society in which they live and are the results of ... in the other countries, partly due to the limitation of means of communication and citizens’ perception The most popular type of advertising is on TV Following is the advertising price chart of ... number of different brands are on the store shelves and thousands of new products are introduced every year The opportunity to advertise new brands gives companies the incentive to develop new brands...
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The role of leadership theory in raising the profile of women in management
... will further explore the recent theories of leadership, and evaluate if these make a further contribution to the recognition of the skills and attributes of women in management or leadership roles ... to the role each theory may have played in raising the profile of women in management or leadership roles Early leadership theories In the 18th and 19th centuries, philosophers suggested a theory ... were not visible in paid employment One of the off shoots of the great man theory was a spawning of new research and theoretical propositions which focused on the traits or characteristics believed...
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Globalization: the Role of Institution Building in the Financial Sector _ The Case Study of China
... performance Role of the central bank The central bank has played a role of policy designing and implementation in the process of institution building in the financial sector The promulgation of The Central ... negotiated price The trade of inter-bank bond market relies on the securities booking system of the CGSDTC and the bond trading system of the inter-bank lending centre The trading system of the national ... bonds In the case of the latter, commercial banks trade with investors at the prices they offer through their outlets, and provide depositing and clearing services to the investors B Roles of the...
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The Role of Genetically Modified Organisms (GMOs) in Beverage Production
... throughout the world bears little resemblance to teosinte, the original ancestor of corn The newer techniques involving genetic engineering, on the other hand, allow for the transfer of a few genes ... than its conventional counterpart; therefore, the Þnal assessment of safety is always comparative The scientiÞc basis of the evaluation process is the concept of “substantial equivalence.” Regulatory ... presence of GM ingredients Unfortunately, standardized methods not currently exist for most of the GM ingredients on the market today Two types of tests are used for the detection of GM material The...
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THE IMPACT OF NEW MEDIA ON ACADEMIC KNOWLEDGE
... more than the sum of all students in the class This then raises the question of the validity and authority of knowledge gained over the Internet How can the learner be sure of the sources of information? ... wide variety of ways to stimulate various forms of learning The most significant feature of the multiple forms of media is that they allow for the presentation of knowledge in a variety of ways Thus ... develop the ability in their students to find their own structure or understanding of the organization of an area of study Multimedia provides an opportunity to offer a variety of different ways of...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25