... undertaking the necessary analysis That, according to USAID, was done at the initial direction ofthe CPA and the subsequent direction ofthe Iraq Reconstruction Management Office and the Office ofthe ... database In return, that ministry provided one trial balance financial report for each ministry/agency The spending units are linked to the Ministry of Finance database via the Internet The following ... comprehensive financial management- informationsystem to enable the Ministry of Finance to effectively execute the national budget The functionalities ofthesystem being proposed will satisfy the IMF recommendations...
... Regional Learning Alliance – workforce development and training/collaborations with business and industry; meeting the training and education needs of businesses within 60 mile radius in Northern Allegheny ... Shippensburg University Small Business Initiative inthe Frehn Center for Management; offering information and assistance to individuals and groups planning to start a new business Best Practice Highlights ... $28,000 in average annual salary) Preserving Value Continuing education is important to preserving the market value of specialized education – particularly in professional fields Continuing education...
... Ala219 ofthe catalytic site and His135 ofthe Mg2+ binding site The most striking result was the loss ofthe psychrophilic character of mutant W260K/A219N (as reflected by a threefold increase ofthe ... value in this temperature range is considerably lowered On the basis ofthe model, the behavior ofthe G261A variant can be interpreted in terms of constraints introduced by the Ala side chain The ... our incomplete understanding ofthe relation between enzyme properties and conformational flexibility limits the exploitation ofthe full potential of protein engineering inthe redesign of psychrophilic...
... evaluate the OS-fitness ofthe clone, the ratio ofthe specific absorbance inthe presence of 10 lgÆmL)1 HEL to that inthe absence of HEL was taken as an index To analyze the effect ofthe type of each ... clarify the effect ofthe interface mutations on the antigenbinding affinity To investigate systematically this unsought relationship between the antigen-binding affinity of Fv and the VH ⁄ VL interaction ... antigen binding, this ‘increasing the affinity by increasing the VH ⁄ VL interaction’ might represent a mechanism of increasing Fv affinity This is also supported by the kinetic study of purified...
... Cardie, Vincent Ng, David Pierce, Chris Buckley Examining theroleof statistical and linguistic knowledge sources in a general-knowledge que stion answering systemIn Proceedings ofthe 6th Applied ... hypernyms inthe answer semantic form Step 3: The assessment ofthe similarities of dependencies Inthe third step, two classes of similar dependencies are considered, generating unications ofthe ... example, inthe case of question Q209: Who invented the paper clip ?, the expected answer type is P ERSON and so is the subject ofthe verb invented , lexicalized as the nominalization inventor...
... change their brand attitude, may suggest an interesting implication for the new brand advertising strategy Instead of focusing on the content ofthe message which only emphasizes the benefits ofthe ... birthday This finding is just reverse ofthe finding of Belk (1973) Ruth, Brunel, Otnes (1999) classified categories of gift-giving into public occasion (i.e., Christmas, Chinese New Year), individual ... situational conditions of gift-giving may differ according to characteristics ofthe gift-giving occasion, whether the presentation ofthe gift is public, private, or anonymous, and whether the gift is...
... important for explaining wilt Inthe case of income, youth living in low-income households experience higher levels of wilt (45%) than youth living in either modest-income (35%) or high-income (23%) ... financing school Conley (2001) finds that a doubling of net worth results in an 8.3% increase inthe probability of attending college Further, when net worth is included inthe model, Black youth are ... youth Youth savings Youth were asked in 2002 whether they had a savings or bank account in their name If they had an account, they were also asked whether they were saving some of this money for...
... that the increase of Glc6P inthe presence of S4048 was caused by the inhibition of Glc6P hydrolysis inthe absence of detectable changes in glucose phosphorylation S4048 causes inactivation of ... [31], for evaluating theroleof Glc6P, we determined the effect of different inhibitor concentrations on the Glc6P content and the rate of glycogen synthesis in hepatocytes incubated with 15 ... Harndahl et al ¨ levels through the interaction of glucokinase with binding proteins [5,6] The glucokinase regulatory protein (GKRP) is a specific inhibitor of glucokinase [5] and also a nuclear...
... the short ones) have all zeroes in them In other words, none ofthe bigrams from the training set appears in these reviews This suggests that the main problem with the bigram model is likely to ... Following Pang et al (2002), we use frequency as presence In other words, the ith element ofthe document vector is if the corresponding unigram is present inthe document and otherwise The resulting ... relation is capturing two different situations, one in which the author himself likes the movie, and inthe other, the author’s cousin likes the movie The overgeneralization resulting from these “stemmed”...
... strong indications for the involvement of a bacterial P450 inthe hydroxylation of octane in Rhodococcus rhodochrous, theroleof bacterial P450s in alkane degradation in addition to the well-established ... biological functions The proteins displaying the lowest similarity to the other P450s are those involved in oxylipin biosynthesis (2–6% amino acid identity) This can be explained in part by their bifunctional ... enzymes The FUM6 protein (CYP505B1) intervenes in one ofthe first steps in fumonisin synthesis by hydroxylation ofthe polyketide-amino acid at C-14 and C-15 (Fig 3) Fum6 deletion mutants of F verticilloides...
... the transaction from the vantage point of firm A, the floatingrate payer The cost of synthetic floating-rate financing is determined by the cost of servicing fixed-rate debt plus the net cost ofthe ... to the desire on the part of firms to hedge cash flows against the effects of interest rate volatility The timing ofthe appearance of interest rate swaps, coming as it did during a period of volatile ... systemof margin requirements, along with the guarantee ofthe exchange clearinghouse (which, in turn, is jointly backed by the paid -in capital ofthe clearinghouse member firms) This system of...
... unfolding of one ofthe I27 modules inthe chain Unfolding then extends the overall length ofthe protein, relaxing the pulling force to a low value As the slack inthe length is removed by further ... gain insight into theroleof solvent hydrogen bonds in protein unfolding, we repeated these SMD simulations of force unfolding ofthe I27 protein in D2O The simulations were completed using the ... repeats ofthe I27 module, in D2O, showing a prominent hump inthe rising phase ofthe initial force peaks which cannot be fitted with the worm-like chain (WLC) model (thin lines) B) The hump begins...
... than those inthe lipids ofthe surrounding membrane In fact, this fatty acid composition favors a tighter packing of phospholipids and cholesterol, increasing the rigidity of these domains [32–35] ... extraction during lipid raft isolation Moreover, these studies have provided some insights into the significance ofthe localization ofthe P2X7 receptors in lipid rafts regarding the regulation of intracellular ... formulation ofthe ‘lipid raft’ hypothesis inthe context of membrane transport in polarized epithelial cells [27] It was postulated that domains rich in cholesterol and sphingolipids are preformed in the...
... contribute to the optimization of electrostatic charges balance of pfLamA inthe native state, independently of their interaction with calcium Theroleof electrostatic interactions in protein stability ... [2] The solid lines through the mutants unfolding data points (lled symbols) are intended to guide the eye ofthe reader and not represent the tting ofthe data Reversibility points are indicated ... binding of calcium to the mutant proteins in native conditions The single and combined mutations dramatically decrease the thermodynamic stability ofthe proteins with a signicant decrease of...