the role of liver x receptor in hepatic de novo lipogenesis and cross talk with insulin and gluc
Báo cáo khoa học: "The role of adjuvant pelvic radiotherapy in rectal cancer with synchronous liver metastasis: a retrospective study" doc
... and the tendency of cancer cells to deposit and multiply in the liver after passing through the portal system may explain the organ-specific metastasis of colorectal cancer [7] Patients with liver ... to the lungs, bone, and other extra -hepatic sites Resection of rectal tumors and treatment of liver metastases can benefit patients by reducing tumor burden and slowing the progression of liver ... was delivered to the whole pelvis including the tumor bed and pelvic lymph nodes and a boost dose of to 12.6 Gy was delivered to the tumor bed in a 1.8 Gy daily fraction Boost volume consisted of...
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Characterization of liver x receptor and retinoid acid receptor mediated response with transcriptome and histological analysis in zebrafish liver
... apoptosis in the liver parenchyma The blunt ends or single base overhangs 25 of 3’-OH ends in the fragmented DNA were labeled with the digoxigenin-nucleotide and then were bounded to anti-digoxigenin ... effects of LXR agonists as reported in rodent models This included up-regulation of LXR-targeted genes suggesting LXR activation, increased apoptotic activity in the liver and induced hepatic ... the phenotypic changes in uterine and revealed that uterine growth and maturation are preceded and accompanied by a complex molecular program, beginning with the induction of genes involved in...
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Tài liệu The Role of Public Regional Universities in Community and Economic Development doc
... business and industry; meeting the training and education needs of businesses within 60 mile radius in Northern Allegheny County West Chester University Institute for Education, Excellence, and ... educational institutions Collaboration with business and government Economic Development Programs and Initiatives Business accelerators and/ or entrepreneurial initiatives Linking teaching and research ... Research and Economic Development Business Accelerator – collaborating with business and industry and business accelerator/entrepreneurial activities; building a more diversified business base Edinboro...
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Tài liệu Báo cáo Y học: Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase pdf
... value in this temperature range is considerably lowered On the basis of the model, the behavior of the G261A variant can be interpreted in terms of constraints introduced by the Ala side chain The ... substitution of Tyr269 fi Ala was designed with the aim of reducing the spatial constraints originating from the side-chain interactions between Tyr269 and Ala261 (Fig 2C) The main difference between the ... properties and conformational flexibility limits the exploitation of the full potential of protein engineering in the redesign of psychrophilic enzyme properties [15] In particular, the effects of local...
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Báo cáo khoa học: The role of interface framework residues in determining antibody VH ⁄ VL interaction strength and antigen-binding affinity pptx
... antigen-dependency To evaluate the OS-fitness of the clone, the ratio of the specific absorbance in the presence of 10 lgÆmL)1 HEL to that in the absence of HEL was taken as an index To analyze the ... for these antibodies, the role of the VL domain might be to increase the affinity by supporting the VH domain The phenomenon may also be observed in the chain shuffling experiments As antigen-induced ... binder, to describe the relationship, and also to identify key residues in determining the interdomain interaction strength Results Construction of an FR2 combinatorial library To investigate the possible...
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Báo cáo khoa học: "The Role of Lexico-Semantic Feedback in Open-Domain Textual Question-Answering" ppt
... keywords, all the inections of the verb are also considered Therefore, the initial query is expanded into: QUERY(Q209): paper AND clip AND (invented OR ) inventor OR invent OR invents) QUERY(Q258): ... similar dependencies are considered, generating unications of the question and answer semantic forms: Class L2-1: there is a one-to-one mapping between the binary dependencies of the question and binary ... keywords and a ltering mechanism, that retains only those passages containing the expected answer type Both the question keywords and the expected answer type are identied by using the dependencies derived...
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Báo cáo " THE ROLE OF GIFT RECIPIENT PERCEPTION IN CHANGING BRAND ATTITUDES AND GIVER - RECIPIENT RELATIONSHIP " potx
... sources of mixed feelings Merton and Barber (1976) described the sociological ambivalence as follows: “ the ambivalence is located in the social definition of roles and statuses, not in the feeling-state ... gifts they would consider much about the relationship between the giver and the receiver By examining factors considered important when choosing gifts, Othman and Lee explored the priority of the ... antecedents: (1) the perception of the existing relationship, (2) the gift, (3) the ritual context; and (4) his/her emotional reactions The convergence of these antecedents affects six types of relationship...
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Báo cáo khoa học: "Examining the Role of Linguistic Knowledge Sources in the Automatic Identification and Classification of Reviews" doc
... renders dependency information not useful for polarity classification Additional experiments are needed to determine the role of dependency relations when stemming in MINIPAR is disabled 617 The ... of improving performance To determine the reason, we examine the n-grams and the dependency relations that are extracted from the nonreviews We find that only in a few cases these extracted objective ... and E Hovy 2004 Determining the sentiment of opinions In Proc of COLING, pages 1367–1373 M Koppel and J Schler 2005 Using neutral examples for learning polarity In Proc of IJCAI (poster) D Lin...
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Báo cáo khoa học: The role of cytochrome P450 monooxygenases in microbial fatty acid metabolism pdf
... hexadecane to its primary product 1-hexadecanol, but also further oxidizes this component to hexadecanal, hexadecanoic acid, 1,16hexadecandiol, 16-hydroxyhexadecanoic acid and even 1,16-hexadecanedioic ... demonstrated towards lauric acid, resulting in the synthesis of mainly x- 1 hydroxylated 216 lauric acid, suggesting a role in the lipid oxidative metabolism Interestingly, the percentage of the ... located in a gene cluster and three of them are P450 enzymes The FUM6 protein (CYP505B1) intervenes in one of the first steps in fumonisin synthesis by hydroxylation of the polyketide-amino acid...
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The Role of Interest Rate Swaps in Corporate Finance doc
... and swap it into synthetic floating-rate debt rather than simply issuing floating-rate debt at the outset? The next two sections explore the rationales that have been offered to explain the widespread ... Mechanics of a Fixed/Floating Swap The quoted price of an interest rate swap consists of two different interest rates In the case of a fixed/floating swap, the quoted interest rates involve a fixed and ... agreement are determined by adding the net payments required of a fixed-rate payer to the cost of servicing its outstanding floating-rate debt Period t cost of servicing outstanding short-term debt +...
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A Single-Molecule Perspective on the Role of Solvent Hydrogen Bonds in Protein Folding and Chemical Reactions pptx
... rapidly, causing the unfolding of one of the I27 modules in the chain Unfolding then extends the overall length of the protein, relaxing the pulling force to a low value As the slack in the length ... bonds within the protein By substituting hydrogen with deuterium in the protein we will measure the force dependency of a range of protein reactions and determine how the dynamics is linked to the ... unfolding the I27 protein in D2O The pulling coordinate for the separating b-strands is defined as the distance between the first amino acid of strand A’ (Y9) and the last amino acid of strand G...
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The Role of Digital Identity Management in the Internet Economy doc
... maximising the potential benefits of its use, including across domains to deliver joined-up services over the Internet The scope of the Primer is limited to the management of the digital identities ... organisations and individuals, confident in the identities of those with whom they are dealing Without trust, individuals may develop a sense of vulnerability and insecurity regarding their online activities ... to take into account in the assessment of the security risks to − and privacy impact on − the delivery of online services, and in determining appropriate levels of security In the case of sensitive...
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Báo cáo khoa học: Membrane compartments and purinergic signalling: the role of plasma membrane microdomains in the modulation of P2XR-mediated signalling pot
... subfamily of receptors in cellular signalling make them attractive therapeutic targets The coupling between stimulation of the P 2X receptor and the generation of intracellular signalling cascades is ... signalling pathway activated by the P 2X7 greatly depended on the topology of the receptor at the cell surface The P 2X7 receptor is much longer than the other P 2X receptors It has a long intracellular ... muscarinic receptors, endothelin receptors, rhodopsin) are located in lipid rafts [65–70] where they are in close proximity to their transducing GTP-binding protein (Gs, Gi, Go, Gq and transducin...
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Báo cáo khóa học: The role of N-linked glycosylation in the protection of human and bovine lactoferrin against tryptic proteolysis pdf
... 20, 484–487 23 Brines, R.D & Brock, J.H (1983) The effect of trypsin and chymotrypsin on the in vitro antimicrobial and iron-binding properties of lactoferrin in human milk and bovine colostrum Unusual ... considering oral application of lactoferrin where the protein has to survive the harsh environment of the gastrointestinal tract Thus, on the basis of this study, rhLF may be preferred over bLF in ... chromatography as described in the Materials and methods The left and right abscissas indicate the absorption at 280 nm and NaCl concentration (M), respectively The inserts provide the N-terminal protein sequencing...
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Beautiful Places: The Role of Perceived Aesthetic Beauty in Community Satisfaction docx
... 6,00 Total % % within Count % % within within % % within within % % within within % % within within % % within within CS within Gender CS Gender CS Gender CS Gender CS Gender CS Gender Male 293 ... satisfied Count % % within Count within % % within Count within % % within Count within Extremely Satisfied % % within Count within Total % % within Count within % % within within CS CS Age CS Age ... % % Count % % Count % % Count % % Count % % Count within within within within within within within within within within Count % % within within CS C
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The role of PDO/PGI labelling in Italian consumers’ food choices
... observe the factors that influence the perception and the purchasing attitude towards PDO/PGI products, to analyse the role of labelling in influencing consumers’ choices and ascertain the existence ... card with Asiago cheese During the interviews 46% of the total sample selected the Mortadella with the PGI mark, 43% the one without the PGI mark and the remaining 11% stated no preference The ... sample of 400 Italian consumers to observe the factors that influence the perception and the purchasing attitude towards such products and the role of logos on the label in influencing their choices...
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Báo cáo sinh học: " Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1" pot
... Discussion The current study was initiated to determine if innate resistance to HSV-1 is dependent on NK cells and their capacity to deliver IFN-γ to sites of viral infection Despite Page of 15 (page ... mouse model may grossly underestimate the importance of NK cells in human resistance to HSV-1 The viral ICP47 protein binds human TAP1 with an extraordinarily high-affinity, and thus renders human ... ocular inoculation, mice were anaesthetized by intraperitoneal (i.p.) administration of xylazine (6.6 mg/kg) and ketamine (100 mg/kg) Mice were inoculated by scarifying the cornea with the blunted...
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Báo cáo hóa học: " The role of single N-glycans in proteolytic processing and cell surface transport of the Lassa virus glycoprotein GP-C" ppt
... Next we determined the effect of the individual N-glycans on the maturation cleavage by analysing the presence of the cleaved subunit GP-2 Disruption of the N-glycosylation sites within the GP-1 ... for correct folding and intracellular transport of viral glyco- proteins, as shown for instances for influenza hemagglutinin [19] In order to investigate the importance of the individual N-glycosylation ... analysing the role of glycosylation of GP in the correct viral context Conclusion Taken together, our study suggest that individual N-linked oligosaccharides of the Lassa virus glycoprotein differ...
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báo cáo hóa học:" Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1" pot
... Discussion The current study was initiated to determine if innate resistance to HSV-1 is dependent on NK cells and their capacity to deliver IFN-γ to sites of viral infection Despite Page of 15 (page ... mouse model may grossly underestimate the importance of NK cells in human resistance to HSV-1 The viral ICP47 protein binds human TAP1 with an extraordinarily high-affinity, and thus renders human ... ocular inoculation, mice were anaesthetized by intraperitoneal (i.p.) administration of xylazine (6.6 mg/kg) and ketamine (100 mg/kg) Mice were inoculated by scarifying the cornea with the blunted...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25