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the role of epigenetics in the developmental origins of health and disease

Báo cáo khoa học:

Báo cáo khoa học: "The conceptualisation of health and disease in veterinary medicine" pdf

Báo cáo khoa học

... epidemiology, internal medicine and other areas Definitions of health and disease found in various textbooks of veterinary medicine are examined and categorised Furthermore, the implications of the different ... medicine, e.g veterinary pathology, internal medicine and epidemiology The aim of the present study is to examine how the concepts of "health" and "disease" are defined in veterinary textbooks in ... directly or indirectly, health and disease in animals Therefore, it is logical to examine how different concepts of disease are used within veterinary medicine, and to examine textbooks in veterinary...
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Tài liệu Báo cáo khoa học: Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enol pyruvyl transferase docx

Tài liệu Báo cáo khoa học: Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enol pyruvyl transferase docx

Báo cáo khoa học

... enthalpies of binding and stoichiometries were determined from the binding isotherm by fitting a : binding model to the data using the software provided by the manufacturer Results Reaction of fosfomycin ... replacement of R120 by lysine reduces the probability of forming the fully closed form of the protein The results obtained with the K22V/R120K double mutant protein point toward a central role of arginine ... chain of K22 participates in fosfomycin binding, thus providing a rationale for the loss of fosfomycin binding to the K22V and K22E mutant proteins However, two other positively charged amino...
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The Role of Small and Large Businesses in Economic Development doc

The Role of Small and Large Businesses in Economic Development doc

Tài chính doanh nghiệp

... well They include constraints on the supply of labor and other inputs, upward pressure on wages and rents, congestion of infrastructure, and (if fiscal incentives are provided to the locating ... innovation Small firms are the great innovators in some industries, while large firms are the great innovators in others Moreover, small and large businesses interact in innovative activity The ... growth from the second quarter of 2000 into job classes using beginning size of firm, mean size of firm over the period, and end size of firm If the beginning size of the firm is used to classify...
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Báo cáo khoa học: Role of DptE and DptF in the lipidation reaction of daptomycin ppt

Báo cáo khoa học: Role of DptE and DptF in the lipidation reaction of daptomycin ppt

Báo cáo khoa học

... The motif present in DptF is GLDSV, indicating that this putative ACP domain is one of the few ACPs in which valine replaces isoleucine (I) or leucine (L) in the conserved sequence To determine ... carrier proteins (ACPs) [14,15] The genes dptE and dptF are localized immediately upstream of the NRPSs of A21987C The resulting proteins DptE and DptF were predicted to be involved in the lipidation ... Assay Fig In vitro phosphopantetheinylation of apo-DptF and apoAcpK Coomassie blue-stained SDS–PAGE gel (left) and in- gel fluorescence (right) of the fluoresceinyl-ACP (+) indicates the reaction...
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The Role of Gestures and Facial Cues in Second Language Listening Comprehension pptx

The Role of Gestures and Facial Cues in Second Language Listening Comprehension pptx

Kỹ năng nghe tiếng Anh

... understand the meaning of the questions in this section Each session took 30 including instructions at the beginning, the listening comprehension task, and completion of the questionnaire The questionnaire ... placement in the IEP was determined on the basis of an in- house placement test of listening, reading, and writing skills (reliability coefficients for the listening and reading sections of this ... the listening task so as not to bias any of the responses Results and Discussion To give the reader a better idea of the types of gestures the participants saw in the lecture, discussion of the...
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Bringing the Hidden Giants to the Footlight: the Role of Savings and Retail Banks in Increasing the Level of Access to Financial Services docx

Bringing the Hidden Giants to the Footlight: the Role of Savings and Retail Banks in Increasing the Level of Access to Financial Services docx

Ngân hàng - Tín dụng

... businesses, the traditional target client group of savings banks By capturing and channelling more of the remittances into the financial system and intermediating the flow of the resources, savings ... disbursing of loans and collecting loan repayments Another promising track for savings banks is to invest their savings deposits in microfinance institutions by specialising 18 Microfinance Information ... countries and in Latin America and Asia, the figures also remain well below the average requirement of the banking system The microcredit schemes of savings banks Although savings banks are savings...
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The Role of Savings and Wealth in Reducing ―Wilt‖ between Expectations and College Attendance pdf

The Role of Savings and Wealth in Reducing ―Wilt‖ between Expectations and College Attendance pdf

Ngân hàng - Tín dụng

... important for explaining wilt In the case of income, youth living in low-income households experience higher levels of wilt (45%) than youth living in either modest-income (35%) or high-income (23%) ... accumulating school savings may have effects apart from financing school Conley (2001) finds that a doubling of net worth results in an 8.3% increase in the probability of attending college Further, ... for their youth Youth savings Youth were asked in 2002 whether they had a savings or bank account in their name If they had an account, they were also asked whether they were saving some of this...
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Báo cáo khoa học: Tertiary structure in 7.9 M guanidinium chloride ) the role of Glu53 and Asp287 in Pyrococcus furiosus endo-b-1,3-glucanase pot

Báo cáo khoa học: Tertiary structure in 7.9 M guanidinium chloride ) the role of Glu53 and Asp287 in Pyrococcus furiosus endo-b-1,3-glucanase pot

Báo cáo khoa học

... role in protein stability [8], and their involvement in interactions with cations offers new perspective in the analysis of the contribution of ions as cofactors in protein folding [38] and in ... those observed for the wild-type, indicating the involvement of Glu53 and Asp287 in the interaction with the cation (Fig 1E,F) The regain of aromatic chirality at 295 nm and in the 260270 nm region ... [2] The solid lines through the mutants unfolding data points (lled symbols) are intended to guide the eye of the reader and not represent the tting of the data Reversibility points are indicated...
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Báo cáo khoa học: The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein ppt

Báo cáo khoa học: The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein ppt

Báo cáo khoa học

... ADAM10 and TACE are involved in the shedding of APP, neither ADAM is involved in the shedding of ACE Furthermore we show that APMA can distinguish between the shedding of ACE and APP Materials and ... expressing ACE were transfected with the ASOs and then exposed to APMA and the levels of soluble ACE in the medium examined (Fig 5) APMA caused a twofold increase in the shedding of ACE from the ... ADAM10 and TACE play a role in the a-secretase shedding of APP, neither protease was responsible for the shedding of ACE APMA stimulates the shedding of ACE but not APP The effect of the organomercurial...
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báo cáo sinh học:

báo cáo sinh học:" The role of nurses and midwives in polio eradication and measles control activities: a survey in Sudan and Zambia" pdf

Điện - Điện tử

... facility level in Zambia served in the capacity of district managers of health programmes The finding that the nurses in Sudan were less involved in planning of activities (15.2% in polio and in measles) ... prevention of diseases; caring for, supporting and comforting clients; continuously assessing and monitoring health needs and responses to interventions; advocacy and education of clients and communities; ... information on EPI and supplementary vaccination activities in the district; (2) overall numbers and categories of health workers in the district; (3) the role of nurses and midwives in EPI and supplementary...
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báo cáo hóa học:

báo cáo hóa học:" Impact of recent life events on the health related quality of life of adolescents and youths: the role of gender and life events typologies in a follow-up study" potx

Hóa học - Dầu khí

... part of the risk group In the case of the first LEs combination exposed at Table of breaking up with a boyfriend/girlfriend and failing a grade in school involves a sufficient impact to be part of ... al.: Impact of recent life events on the health related quality of life of adolescents and youths: the role of gender and life events typologies in a follow-up study Health and Quality of Life Outcomes ... Spain Authors’ contributions JMV, LR, and JA participated in the conception and design of the study EVO, SRF, GV and JAPV analyzed the data EVO, JMV, MH, MF, LR and JA participated in the drafting...
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Research for a Future in Space: The Role of Life and Physical Sciences ppt

Research for a Future in Space: The Role of Life and Physical Sciences ppt

Sức khỏe giới tính

... Engineering in providing services to the government, the public, and the scientific and engineering communities The Council is administered jointly by both Academies and the Institute of Medicine ... president of the National Academy of Engineering The Institute of Medicine was established in 1970 by the National Academy of Sciences to secure the services of eminent members of appropriate professions ... autonomous in its administration and in the selection of its members, sharing with the National Academy of Sciences the responsibility for advising the federal government The National Academy of Engineering...
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Báo cáo khoa học:

Báo cáo khoa học: "Short-term variations and long-term changes in oak productivity in northeastern France. The role of climate and atmospheric CO 2" pot

Báo cáo khoa học

... curves for the growth indices of the ’young’ (< 60 years) and the ’old’ (> 65 years) rings (cambial age) In the final stage, the curve of the growth indices IC0 was modelled according to the available ... III and IV) The case of July appears somewhat disconcerting because the related parameters and the from years y, y- and y- on the hand, and years y- and y- on the other, can be given opposing ... structure and on the rooting of the trees owing to the impermeability of the subsoil Of the recent dendroecological studies that demonstrate a long-term increase in the wood production rate of forest...
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Báo cáo y học:

Báo cáo y học: "The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis" ppt

Báo cáo khoa học

... ubiquitination of various target proteins, and the intracellular domain of the Notch receptor (involved in the maintenance of cells in an undifferentiated state), both of which notably contain ankyrin repeat ... vascularity and inflammatory signalling pathways In the present review we focus on current knowledge of the regulation of the HIF pathway, and then consider the potential role of hypoxia in the pathogenesis ... molecular basis of hypoxia tolerance, not only in muscle but also in numerous other diseases (including cancer and RA) and in settings where induction of hypoxia tolerance might be of therapeutic...
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báo cáo khoa học:

báo cáo khoa học: "A Study to investigate the role of p27 and Cyclin E immunoexpression as a prognostic factor in early breast carcinoma" pptx

Báo cáo khoa học

... cyclin E in all invasive carcinomas and in the subgroup of IDC This may be due to the early stage of the disease The major limitation of this study is the small size of the study group Further ... positive staining in less than 5% of nuclei); low staining = moderate to strong positive staining in 5% to 50% of nuclei; high staining = moderate to strong positive staining in more than 50% of nuclei ... follow up of more than 36 months There were 59 infiltrating ductal carcinomas (not otherwise specified and variants) and infiltrating lobular carcinomas The infiltrating ductal carcinoma group included...
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Báo cáo khoa học:

Báo cáo khoa học: "The role of photoperiod and temperature in the induction and the release of dormancy in Pinus sylvestris L. seedlings" potx

Báo cáo khoa học

... at the start of night prolongation, or 12 wk, an important role in the possibility of the buds to attain a deeper stage of dormancy Only the 12 wk old plants of northern origin had no flushing ... the chilling requirement to break winter dormancy in Scots pine has been stressed (e.g., Wareing, 1951; Vegis, 1965; Sarvas, 1974) In the following,I will use the working definition of dormancy ... (Fig 2) The same was true for the higher temperature 25/15°C compared with 25/5°C Dormancy breaking treatments of and wk had a dramatic influence, hastening the tilushing rate, especially in the...
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Báo cáo y học:

Báo cáo y học: "The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis" pps

Báo cáo khoa học

... ubiquitination of various target proteins, and the intracellular domain of the Notch receptor (involved in the maintenance of cells in an undifferentiated state), both of which notably contain ankyrin repeat ... vascularity and inflammatory signalling pathways In the present review we focus on current knowledge of the regulation of the HIF pathway, and then consider the potential role of hypoxia in the pathogenesis ... molecular basis of hypoxia tolerance, not only in muscle but also in numerous other diseases (including cancer and RA) and in settings where induction of hypoxia tolerance might be of therapeutic...
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Báo cáo khoa học:

Báo cáo khoa học: " The role of NH4Cl and cysteine proteases in Human Papillomavirus type 16 infection" ppsx

Báo cáo khoa học

... Figure Lack of HPV16 Infection in the absence of cathepsin B Lack of HPV16 Infection in the absence of cathepsin B HPV16 infection levels in cathepsin B and cathepsin L deficient (-/-) and wild ... cathepsin B or cathepsin L protease, Figure Cathepsin B and L treatment of HPV16 increases binding Cathepsin B and L treatment of HPV16 increases binding Reporter virus binding was compared in ... cathepsin L enhanced infectivity by cleaving and removing a highly glycosylated mucin domain in the Ebolavirus glycoprotein and resulted in increased binding suggesting that cathepsins are indeed...
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Báo cáo y học:

Báo cáo y học: "The role of pleiotrophin and β-catenin in fetal lung development" doc

Báo cáo khoa học

... [66] The binding of PTN with syndecan-3 induces neurite outgrowth of embryonic neurons [67] Heparitinase, which cleaves the heparin sulfate chain and disrupts the binding of PTN, inhibits PTN-induced ... tips It binds to the FGFR2b on the epithelial cells and transmits a signal to induce the initiation of the lung bud [17-22] Recombinant FGF10 alone can induce budding in the lung epithelial explants ... and ciliated epithelial cells in the adult lung [11] HFH-4 induces the expression of βtubulin IV in the pseudoglandular stage, and promotes the differentiation of ciliated epithelial cells Other...
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