the role of anti human leukocyte antigen antibodies in chronic allograft injury
Báo cáo y học: "Role of anti-cyclic citrullinated peptide antibodies in discriminating patients with rheumatoid arthritis from patients with chronic hepatitis C infection-associated polyarticular involvement" potx
Ngày tải lên :
09/08/2014, 01:23
... for detection of anti- filaggrin antibodies [19] were largely overcome after the discovery of citrulline residues as the main antigenic target of AKA and anti- filaggrin antibodies and the subsequent ... Labinstruments, Grödig, Austria) at 550 nm Anti- CCP antibodies were considered to be positive when the absorbance was higher than the cut-off of the kit (5 U/ml) The concentration of anti- CCP antibodies ... rheumatoid arthritis: the role of anti- CCP antibodies Am Clin Lab 2002, 21:34-36 Pinheiro GC, Scheinberg MA, Aparecida da Silva M, Maciel S: Anti- cyclic citrullinated peptide antibodies in advanced rheumatoid...
- 5
- 312
- 0
Báo cáo y học: "The role of mast cells and fibre type in ischaemia reperfusion injury of murine skeletal muscles" pot
Ngày tải lên :
11/08/2014, 08:21
... restores the susceptibility of skeletal muscles to IR injury irrespective of the other abnormalities in these mice The role of mast cells has not been considered when investigating the susceptibility ... though the latter contained twice the density of mast cells, indicate that there is also a genetic component to IR injury Our data would support the hypothesis that there is a base line level of ... variation in the period of ischaemia, the muscle temperature during ischaemia and the period of reperfusion allowed for manifestation of the reperfusion injury Idstrom [12] utilised a period of 2,...
- 7
- 400
- 0
Báo cáo y học: "α The role of anti-α-actinin antibodies in the pathogenesis and monitoring of lupus nephritis" pot
Ngày tải lên :
12/08/2014, 11:22
... serum anti- α-actinin antibodies in lupus patients was associated with a 2.5-fold increase in the prevalence of LN [14] Finally, levels of anti- α-actinin antibodies correlated with those of anti- DNA ... expression of α-actinin may determine the extent of antibody deposition [10] These observations, together with the demonstration that α-actinin immunization generates nephritogenic autoantibodies ... increased anti- α-actinin antibodies [5,14] Moreover, the lack of a difference in α-actinin antibody titers between patients with LN and controls is in contrast to what was reported previously in two independent...
- 3
- 337
- 0
Báo cáo y học: " The role of cyclin D2 and p21/waf1 in human T-cell leukemia virus type 1 infected cells" potx
Ngày tải lên :
13/08/2014, 13:20
... cyclin binding motifs, one at the N- and the other at the C- terminus [20] p21/waf1 (mut) is mutated at the N-terminus and is therefore still able to bind to cyclins through the C-terminus, making ... 102 CEM mins 30 mins 45 mins 20 45 mins mins 25 30 mins 32 P Incorporation 30 15 H1 10 -5 H1 mins 30 mins 45 mins Time Figure Increased levels of cyclin E/cdk2 kinase activity in HTLV-1 infected ... onset of cdk2 kinase activity [28,30] Tax also has the ability to increase cdk4 associated kinase activity in HTLV-1 infected cells by binding to p16/INK4A, resulting in the inability of p16/INK4A...
- 17
- 299
- 0
Báo cáo khoa học: Local stability identification and the role of key acidic amino acid residues in staphylococcal nuclease unfolding ppt
Ngày tải lên :
07/03/2014, 21:20
... near the flexible C terminus of SNase Changes in the fluorescence intensity of W140 reflect a change in the surrounding hydrophobic environment of the tryptophan and thus indicate a change in the ... decreases in DHcal of greater than 20% compared with the wild-type protein, indicating that these charged residues have a strong in uence on the unfolding of SNase The heat denaturation curves for the ... 33% lower than that of the wild-type protein The thermodynamic parameters of the glycine sustitution mutants also differed greatly from the wild-type protein The Tm values of these mutants ranged...
- 8
- 462
- 0
Báo cáo khoa học: Characterization of the role of a trimeric protein phosphatase complex in recovery from cisplatin-induced versus noncrosslinking DNA damage potx
Ngày tải lên :
30/03/2014, 04:20
... role in the cisplatin response [9] Cisplatin interferes with DNA function by causing intrastrand and interstrand crosslinking of nucleotide bases and, in replicating cells, DNA damage usually induces ... and the presence of ionizing radiation [12], and in the present study, in the absence and the presence of cisplatin In addition, we showed that Pph3p directly or indirectly binds to cH2AX, indicating ... tagged proteins (Fig 3C, top panel) HA3–Pph3p interacted with increasing amounts of cH2AX generated in the presence of increasing doses of MMS (Fig 3C) and even with the low levels of cH2AX that...
- 11
- 362
- 0
the role of ''too big to fai'' status in bank merger activity
Ngày tải lên :
03/06/2014, 02:17
... states there was limited uniformity in banking The start of the free banking era began with the expiration of the charter of the Second Bank of the United States in 1836 Combined with the wave of ... of the outcomes of the collapse was again another government solution of bank insurance through the FDIC The main component of the National Banking Acts of 1933 and 1935 was the creation of the ... the failure of the bank would undermine the financial stability of the economy Only then would the FDIC be entitled to protect all the liabilities of the bank against loss Further, enacting the...
- 160
- 318
- 0
báo cáo hóa học:" The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization" pptx
Ngày tải lên :
20/06/2014, 04:20
... heal the defect The increase in cell replication in a mineralizing cell likely represents a de-differentiation from the mineralizing phase to the growing phase, and increases expression of GFs ... BMP-2, the yin and yang of mineralization: Contrast of effect of 24 hours of treatment with FGF-2 or BMP2 on fold increase in abundance of mineralization-related gene expression Mineralizing MC3T3-E1 ... five times in room temperature phosphate buffered saline (PBS) and fixed We then visualized the mineralizing cells with 2% Alizarin Red After rinsing in distilled water and air drying the samples,...
- 8
- 547
- 0
báo cáo hóa học:" The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization" pdf
Ngày tải lên :
20/06/2014, 07:20
... heal the defect The increase in cell replication in a mineralizing cell likely represents a de-differentiation from the mineralizing phase to the growing phase, and increases expression of GFs ... BMP-2, the yin and yang of mineralization: Contrast of effect of 24 hours of treatment with FGF-2 or BMP2 on fold increase in abundance of mineralization-related gene expression Mineralizing MC3T3-E1 ... five times in room temperature phosphate buffered saline (PBS) and fixed We then visualized the mineralizing cells with 2% Alizarin Red After rinsing in distilled water and air drying the samples,...
- 8
- 460
- 0
báo cáo hóa học:" Impact of recent life events on the health related quality of life of adolescents and youths: the role of gender and life events typologies in a follow-up study" potx
Ngày tải lên :
20/06/2014, 16:20
... part of the risk group In the case of the first LEs combination exposed at Table of breaking up with a boyfriend/girlfriend and failing a grade in school involves a sufficient impact to be part of ... part of a risk group In addition, the combination of these two LEs seems to be usual In fact, not only the LCUs sum score determine the effect, it’s the undesirability of these LEs what makes ... strengths Findings regarding the effect of LEs on HRQoL have almost always been presented from clinical samples [16,45,46], and the present work is one of the few to study the association in a general...
- 9
- 583
- 0
Báo cáo khoa học: "the Role of Non-Timber Forest Products (NTFPs) in Livelihood Strategies and Household Economies in a Remote Upland Village in the Upper Ca River Basin, Nghe An, Vietnam" pdf
Ngày tải lên :
06/08/2014, 19:20
... gap-filling supplement during the agricultural season and for diversifying sources of income The roles of NTFPs in Que seemed less important than those in Tha Lang, although cash income from NTFPs in ... From the results of the livelihood strategy analysis, we analyzed the role of NTFPs in the strategies and household economic activities The indicators surveyed among the 30 households and their ... these are the main source of medicine in the hamlet A diverse array of medicinal plants is gathered year round, and most households also used medicinal plants to purify daily drinking water Firewood,...
- 11
- 390
- 0
Báo cáo lâm nghiệp: "The role of Hylastes cunicularius Erichson (Coleoptera: Scolytidae) in transferring uropodine mites in a mountain spruce forest" pptx
Ngày tải lên :
07/08/2014, 03:22
... overlooked in mountain spruce forests in the Tatra Mountains and, possibly in other mountain areas in Europe too In the study area, the bark beetle acts as a vector of at least four species of uropodine ... the role (function) of H cunicularius in the transfer of phoretic uropodids in a mountain spruce forest Affinity to the legs of H cunicularius is typical of T pecinai (Kršiak 2007) We found the ... population vectoring T pecinai over the period 15th May–30th June 2004 (main flight period of the beetle in the study area) Frequency of occurrence and dominance of abundance of T pecinai were calculated...
- 7
- 426
- 0
Báo cáo y học: "The role of F1 ATP synthase beta subunit in WSSV infection in the shrimp, Litopenaeus vannamei" potx
Ngày tải lên :
12/08/2014, 04:20
... in the work of obtain the 3′-end sequence of bp53 JH involved in design of the study and helped to revise the manuscript All authors read and approved the final manuscript Competing interests The ... plays a role in the WSSV infection Conclusions F1F0-ATP synthase complexes play a central role in the synthesis of ATP in all living organisms, which was originally described from the inner membrane ... SV: Angiostatin binds ATP synthase on the surface of human endothelial cells Proceedings of the National Academy of Sciences of the United States of America 1999, 96:2811-2816 24 Martinez LO, Jacquet...
- 9
- 363
- 0
Báo cáo y học: "What is the role of surfactant and inhaled nitric oxide in lung transplantation" pps
Ngày tải lên :
12/08/2014, 18:21
... considered This interesting approach was successful in the experimental setting of acute lung injury and needs to be verified in clinical indications other than lung transplantation Competing interests ... substitution of surfactant may bridge the patient to recovery of the graft The combination of iNO and surfactant proved to be successful in experimental severe reperfusion injury [15], strengthening Della ... solution the hypothesis that this combination prevents intrapulmonary shunt more effectively than does either intervention alone, and that it reduces inactivation of surfactant substitutes In summary,...
- 3
- 407
- 0
Báo cáo khoa học: "The role of body mass index and diabetes in the development of acute organ failure and subsequent mortality in an observational cohor" doc
Ngày tải lên :
13/08/2014, 03:20
... of BMI in the development of acute organ failure and subsequent mortality in a large, population-based, prospective cohort We also wished to determine the role of DM in modifying the effect of ... analytic cohort Outcome variables The primary outcomes of interest were the risk of the development of acute organ failure within three years of the baseline examination, in- hospital mortality related ... and insulin therapy with its anti- inflammatory properties [32-34] This study has several limitations First, the accuracy of ICD-9CM (the clinical modification of ICD-9) coding in identifying...
- 9
- 501
- 0
Báo cáo y học: "Increased bleeding risk associated with the use of recombinant human activated protein C in patients with advanced liver diseas" potx
Ngày tải lên :
13/08/2014, 08:21
... hospital, seven of whom were not evaluable because of death soon after initiation of APC Of the 34 remaining patients, nine had major bleeding episodes The clinical characteristics of these 34 patients ... bleeding episodes, four died within 28 days of drug administration Interestingly, only one out of 12 patients who had undergone major surgery during their hospitalization experienced a bleeding ... and Chronic Health Evaluation II score, cirrhosis remained independently associated with the risk of a bleeding event (P = 0.02, odds ratio = 23.5, 95% confidence interval = 1.75–315) Of the...
- 2
- 268
- 0
Báo cáo y học: "Consolidating the set of known human protein-protein interactions in preparation for large-scale mapping of the human interactome" ppt
Ngày tải lên :
14/08/2014, 14:21
... extracting protein interactions, the names of human proteins were identified using the CRF algorithm in the complete set of 753,459 Medline abstracts citing the word 'human' Extracting functional interactions ... initial set of interactions, we estimate the scale of the human interactome Results Assembling existing public protein interaction data We first gathered the existing human protein interaction ... highly on the functional, but not the physical interaction, test reviews Version comment The initial list of the interactions and proteins represented in each of the existing human protein interaction...
- 12
- 208
- 0
gjerstad & smith - rethinking housing bubbles; the role of household and bank balance sheets in modeling economic cycles (2014)
Ngày tải lên :
01/11/2014, 18:18
... Analysis The committee determined that a trough in business activity occurred in the U.S economy in June 2009 The trough marks the end of the recession that began in December 2007 and the beginning of ... reflected in the patterns of change in net worth across demographic groups to varying degrees, depending on the rate of homeownership and the proportion of assets invested in housing The decline in ... Perspective In our view, the prominent role of balance sheets is the missing link in answering these questions and accounting for the abrupt turns and reversals as economic thinking and policy...
- 310
- 471
- 0
the role of ikkalpha, ikkbeta and nf-kappab in the progression of breast cancer
Ngày tải lên :
22/12/2014, 21:49
... processed into p52 The processing of p100 to p52 results in the loss of the ankyrin repeats in the C-terminus and allows translocation of the RelB/p52 dimers into the nucleus [107] Similar to the canonical ... expression in the basal cell layer of the epidermis of knockout mice than the wild-type There was also increase in expression of Keratin K14 in the knockout mice Fillagrin and involucrin (late ... 10% of cells or less show membrane staining - 1+, negative = a faint partial staining of the membrane in more than 10% of cells - 2+, borderline = weak to moderate staining in more than 10% of...
- 233
- 425
- 0
Blogging and collective action the role of collective identity and social networks in engendering change
Ngày tải lên :
10/09/2015, 15:52
... process of collective identity building among political bloggers in influencing their crossover from online to offline participation in collective action Taking into account the role of human agency ... debunking Other than information in the form of content, hyperlinks also enable the identification of potential recruits or sympathizers In their 31 study of the hyperlink network of English Speaking ... role of the Internet in social movement studies, this study hypothesizes that through the sharing of similar ideologies in terms of political beliefs and a common vision on the governing of the...
- 293
- 379
- 0