... is strongly associated with the progression of cancer cells to invasive phenotypes and the development of distant metastases A higher incidence of c-Met overexpression was found in AFP-secreting ... metastasis Gastric cancers that secrete AFP are rare The first case was described in 1970 [11] AFP-secreting gastric cancers occur with a frequency of 2% to 6% The prognosis of these cases tends ... Immunohistochemical determination of AFP inthe area ofthe adenocarcinoma was negative (×100) Discussion NF-1, or von Recklinghausen s disease, was first described in 1882 It is a relatively common...
... carbon treatment (PACT) system The schematic diagram ofthe PACT system used in this study is shown in Fig.1 The activated sludge reactor was madeof polyacrylate and consists of an aeration tank ... this study is to clarify the effect of DOM and biofilm onthe adsorption capacity of PAC inthe aeration tank of PACT process The specific conclusions derived from this study are as follows: ... inorganic constituents as the synthetic waste water (Table 1) but has times higher concentration Five ml ofthe activated sludge from the control reactor was suspended into 495 ml ofthe glucose medium...
... biofuel/biomass production based on microalgae is proposed in this paper CONCEPT DESIGN Design and description ofthe novel process A novel process being proposed in this study for domestic wastewater ... removes organic pollutants in wastewater, large amount of excess sludge is generated during the assimilation of organics by microorganisms inthe activated sludge Therefore, the wastes are transferred ... reclamation coupled with biofuel/biomass production based on microalgae considers wastewater as a kind of resource instead of just waste, and shifts the wastewater treatment process from being a...
... This causes several problems Burning the timber increases the level of carbon dioxide inthe air Less trees means less carbon dioxide absorbed for photosynthesis Soil is eroded as it is exposed ... resources Humans are using up the earth s resources, including fossil fuels Burning fossil fuels in cars and power stations produces carbon dioxide, sulphur dioxide and other greenhouse gases ... energy sources • Conserve our rapidly diminishing fossil fuel reserves by using solar power or wind power Benefits of conserving endangered species • Ecotourism • Agricultural benefits • Species indicators...
... substitution and types of substitution Chapter 2: The survey This chapter consists of two sections The first section describes such elements related to the methodology ofthe survey as survey setting ... collection The second section presents the results ofthe survey, the analysis of ambiguity caused by ellipsis and substitution through exercises Chapter 3: Findings and discussion This chapter ... ellipsis and substitution The survey exercises consist of three sections The first section deals with multiplechoice exercises including eleven questions in which the students have to circle the...
... with specific instructions The students interest in speaking tasks Students evaluation ofthe effectiveness of speaking tasks at school Students desire for several types of speaking tasks 3.3.2.2 ... be seen that the students interest in speaking tasks, students evaluation ofthe effectiveness of speaking tasks at school, students desire for several types of speaking tasks were shown How often ... preparations for questionnaire administration, administering the questionnaire Phase 1: Preparations for questionnaire administration After finishing designing the final version ofthe survey questionnaires,...
... This causes several problems Burning the timber increases the level of carbon dioxide inthe air Less trees means less carbon dioxide absorbed for photosynthesis Soil is eroded as it is exposed ... resources Humans are using up the earth s resources, including fossil fuels Burning fossil fuels in cars and power stations produces carbon dioxide, sulphur dioxide and other greenhouse gases ... energy sources • Conserve our rapidly diminishing fossil fuel reserves by using solar power or wind power Benefits of conserving endangered species • Ecotourism • Agricultural benefits • Species indicators...
... N122A inthe vicinity of residue 122 The backbone and sidechains ofthe N122A substitution are shown as stereo images in thick ball and stick and the position ofthe Asn122 side-chain ofthe wild-type ... electron density inthe area ofthe substitution is shown in Fig The positions of catalytic residues and all other residues local to the substitution site not differ from the wild-type crystal structure ... residues, only Arg213 is inthe vicinity ofthe active site of RTA In order to establish the role of arginyl residues around the active site of RTA inthe binding of rRNA, a number of RTA variants...
... These results show that TH decreases with increasing crystal size at the slow cooling rate, and does not depend onthe crystal size at the fast cooling rate These results imply that the cooling ... stabilize convex ice surfaces, such stabilization becomes imperfect with an increasing number of weak points onthe ice crystal This supposition is consistent with the data obtained after h of ... The structural characteristics of these fish AFPs and their target ice crystal surface are different from thoseof insect AFPs A faster cooling rate decreases the apparent TH value of fish AFPs,...
... processing, so they could process requests by single and complex tracks, instead of processing all requests on a single-track, first -in/ first -out basis (thus giving agencies the flexibility to respond ... agencies to make available on line are • agency final opinions, including concurring and dissenting opinions, as well as orders, madeinthe adjudication of cases; • statements of policy and interpretations ... agencies (see table 1) Agencies with single-track processing use a first -in/ first -out basis to process all requests As figure shows, the median processing times for agencies that used single-track...
... analyzing and activities understanding is essential required for business process improving and so, activities are the business processes’ building blocks The adoption of ABC will make costs more ... characteristics also is not counted since the limit of survey is Vietnam plants My results need to be assessed by the collection of data from industry specific settings to verify how the industry ... operating systems by determining the cost of a business This cost determining method change the basis to allocate the cost centre for products Or we can say that instead of expenses allocation according...
... Yt = response of interest at time t Standard analysis of business time series involves smoothing trend assessment, assessment of accounting for seasonality, and assessment of exploiting serial ... the economy and competition from other similar businesses The sales forecast then must be supported by plans for adequate investment in assets Next, determining the size ofthe necessary investment: ... knowledge is enhanced base onthe effectiveness of globalization in some ways and the impact of analysis of financial statement onthe boards of managers when making the business decisions Firstly,...
... AMENDMENT MADE BY SUBSECTION (a). Section 127B ofthe Truth in Lending Act is amended by inserting after subsection (a) (as added by subsection (a)) the following new subsection: ‘‘(b) EXCEPTIONS.— ... USE OF TERMS CLARIFIED. Section 127B ofthe Truth in Lending Act is amended by inserting after subsection (g) (as added by subsection (d)) the following new subsection: ‘‘(h) USE OF TERMS. The ... OVER -THE- LIMIT TRANSACTIONS Section 127B ofthe Truth in Lending Act is amended by inserting after subsection (j) (as added by section 3(g)) the following new subsections: ‘‘(k) OPT -OUT OF CREDITOR...
... chain-extension processes (modular assembly line operation) A further source of variance is found inthe nature of association between enzymes inthe clusters; in some systems (Type II) the individual ... bound] and ofthe adjacent TE domain Various sets of incubation conditions, listed in Table 1, were explored The possible adducts onthe various domains are shown in Fig First, the DKS was incubated ... domain MS analysis ofthe KS1 fraction showed that the active site was fully loaded with propionate The absence ofthe free form ofthe KS shows that loading of propionate onto the KS via the...
... H4biopterin/H2biopterin onthe conformational transition (hysteresis) triggered by substrate binding as studied by surface plasmon resonance analysis The effect ofthe pterin cofactors onthe reversible ... hydroxylation reaction) has been a controversial issue and is further discussed below Onthe pterin cofactor binding site Shiman and coworkers [14] have suggested the presence of several putative binding ... proteolysis by trypsin, (b) onthe reversible conformational transition (hysteresis) triggered by substrate binding, as followed in real time by surface plasmon resonance (SPR) analyses, and (c) on the...
... was constructed because the corresponding mutation in Hs-RNASEH2A has been identified as one ofthe disease-causing mutations [30] Tk-G10A was constructed because Ala has the smallest side chain ... the only disease-causing mutations identified in these subunits Thirteen single disease-causing mutations have so far been identified in total in Hs-RNASEH2B [30,31] The parent residues at these ... active as the wild-type protein suggests that reduction of RNase H2 activity may not be the only reason why mutations inthe RNase H2 subunits cause AGS Construction of mutant proteins of Tk-RNase...
... obtained inthe case ofthe reaction performed without the enzymes was subtracted from that obtained inthe reactions performed with the enzymes Bottom: the ratio obtained inthe case ofthe control ... ofthe enzymes to heliquinomycin The IC50 values indicated are those calculated inthe present study as well as in a previous investigation [21] Those determined inthe previous investigation ... compilation ª 2009 FEBS Y Ishimi et al Inhibition of MCM4/6/7 helicase with heliquinomycin activities of these two helicases only slightly We also examined its effect on these activities inthe presence...
... mitochondria) was the same as that of samples stopped at the end of a 10-min incubation (samples, m) In addition, in samples with magnesium present inthe medium, the content of cyto-c was the same ... trace e) The data reported in Fig 4B are consistent with and similar to thosein Fig onthe oxidation of exogenous NADH as the expression ofthe activity ofthe complete system Discussion The data ... binding increases, which tentatively could be the consequence of MOM stretching with the disclosure of additional nonspecific binding sites However, this increase is not responsible for the increased...
... decrease ofthe length inthe same series below 15 residues resulted in a loss of activity Finally, scrambling the sequence of LK15(W14)(3.6) [peptide scr-LK15(W14)] strongly decreased its activity, ... advantage ofthe fact that bacteria ofthe class Mollicutes are devoid of an outer membrane and of a cell wall, to avoid possible interferences of these structures inthe interactions between peptides ... peptides ofthe beta-amphi series are also intrinsically capable of killing mollicutes This suggests that within this series, longer peptides should prove more efficient in growth inhibition tests...
... restrained docking simulations ofthe bananin–SARSCoV helicase interaction, aiming to define the sterical requirementsof new antiviral drugs Results and Discussion All the mutations found inthe ... functional roles of A68V and R124W mutations blast analysis onthe 19 complete sequences present inthe NCBI databases for the SARS-CoV membrane protein suggests that the observed conservative substitution ... not interfere inthe interaction ofthe enzyme with its natural substrates The presence ofthe leucyl side chain inthe protein mutant appears to cause steric hindrance to bananin binding, leaving...