the possible role of tissue regeneration and replacement
Báo cáo y học: "The contemporary role of blood products and components used in trauma resuscitation" pdf
... Surgery, Professor of Anesthesiology and Clinical Adjunct Professor of Emergency Medicine at the University of Minnesota Dr Dries also holds the John F Perry, Jr Chair of Trauma Surgery at the University ... direct consequence of the combination of tissue injury and shock Endothelial injury accelerates fibrinolysis because of direct release of Tissue Plasminogen Activator [19,28] Tissue Plasminogen ... (TEG) TEG offers the advantage of providing a real-time graphic representation of clot formation and whole blood Unlike standard laboratory tests, TEG offers analysis of the whole Page 12 of 17 coagulation...
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The evolving role of IT managers and CIOs findings from the 2010 IBM global IT risk study
... Engineer and a member of the IBM Academy of Technology He assists clients in the design and implementation of IT management systems to maximize the value of their IT investment and improve the efficiency ... part of the ongoing research IBM conducts in the area of IT risk, and the first in a series of research surveys that examine this subject The survey, which was conducted in May and June of 2010 ... revenue and profit What’s the risk if the service fails balanced against the benefit of getting the service up and running?” Mark Ernest, IBM Distinguished Engineer When asked to describe their...
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Tài liệu Báo cáo khoa học: A possible role of mitochondria in the apoptotic-like programmed nuclear death of Tetrahymena thermophila Takashi Kobayashi and Hiroshi Endoh docx
... report and our observations of the monomeric form of DePsipher in the autophagosome together, the mitochondria taken in the autophagosome might be broken, once they were incorporated into the autophagosomes ... becomes acidic in the final step of PND [22,23] DePsipher staining of the macronucleus appeared initially during the stage of autophagosome formation, and persisted until resorption of the parental ... Unfortunately, the involvement of mitochondria in PND has not been clarified fully To elucidate the role of the mitochondrion as a key effector we studied the localization of mitochondria during the death...
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Báo cáo lâm nghiệp: "The effects of transplanting stress on photosynthesis, stomatal conductance and leaf water potential in Cedrus atlantica Manetti seedlings: role of root regeneration" pdf
... 3a), and then, from day 14 to day 42, recovered its initial value The start of recovery in A was concomitant to the beginning root regeneration (Fig 3) References Discussion The results of this ... support the previous findings of several authors showing that A (Stupendick and Shepherd, 1980), s g and WP (Sands, 1984; Aussenac and El Nour, 1986) are affected by transplanting stress However, the ... decline of A due planting was to transnot a consequence of re- duced g but was primarily determined by , s alterations of mesophyll photosynthesis This, plus the parallel time course of A and g...
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Possible role of diva in microglial dual effects and the stem cell differentiation
... involved in the development and growth of the CNS and play at least a partial role in the survival of neurons, proliferation of oligodendrocyte precursors and growth of axons (Arenas and Persson, ... used the Northern blot but the expressions of Diva in testis and E15 embryo were opposite and this may be caused by the specificity of the probes The contradiction lies in the expression of Diva ... (McGeer and McGeer, 2001;McGeer and McGeer, 2002) On the other hand, resident microglia play a part in tissue repair after injury and synergistic effects of microglia and astrocytes are needed for tissue...
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Tài liệu Male Reproductive Health Disorders and the Potential Role of Exposure to Environmental Chemicals pdf
... some of the weaknesses and problems that can affect the quality of studies investigating the potential causes of cryptorchidism and hypospadias Quality assessment of the various studies and of the ... registry-based and all were questionnaire-based, so the level of proof that they offer regarding EC exposure and the disorders is relatively poor Nevertheless, the best designed of these studies ... 2008, 2009) and by binding to and blocking the AR (Wilson et al 2008), and these will also induce some of the TDS disorders Male Reproductive Health Disorders and the Potential Role of Environmental...
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Tài liệu Báo cáo khoa học: Structural effects of a dimer interface mutation on catalytic activity of triosephosphate isomerase The role of conserved residues and complementary mutations pptx
... position 13 of the other subunit [25,26], yielding a covalently bridged dimer The 4170 oxidized and reduced forms of the Y74C mutant had very different thermal stabilities While the stability of the ... and in the presence of denaturants [27] Extending these studies, we examine here the effect of increasing the bulk of the residue at position 74 Surprisingly, the Y74W mutant exhibited loss of ... to the WT* enzyme There are two possible reasons for the low activity of the Y74W* mutant: (a) introduction of the bulkier residue at the interface in place of a tyrosine may destabilize the...
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Tài liệu Báo cáo khoa học: Unfolding of human proinsulin Intermediates and possible role of its C-peptide in folding/unfolding pptx
... 0.65 according to the reference [36] The molecular mass of the disulfide isomers of HPI and the enzyme-digested fragments were measured by ESI MS The molecular mass of the mixture of scrambled isomers ... that of insulin [40–42], therefore the presence of the C-peptide should not influence dramatically the conformation of the A- and Fig Refolding of scrambled disulfide isomer G1 to native HPI The ... nm and accumulated twice at the resolution of 1.0 nm with the scanning speed of 50 nmÆ min)1 The cell length was 0.1 cm and the stepwise increment was 0.1 nm Results Reductive unfolding of the...
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Tài liệu Báo cáo khoa học: Models and mechanisms of O-O bond activation by cytochrome P450 A critical assessment of the potential role of multiple active intermediates in oxidative catalysis doc
... intermediate [11] The sum of these ndings points at the involvement of more than one active oxidant in the diverse types of P450-catalyzed substrate processing [1215] The goal of the present perspective ... which small alterations in the environment can cause drastic changes in the reactivity of the active species [76] Further support in favour of the idea of the involvement of a high-valent iron-oxene ... important role in the aromatization process in concert with a histidine residue through facilitating abstraction of the 2b-hydrogen in the A-ring of the C-19 substrate and donation of a proton to the...
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THE FUNDAMENTAL ROLE OF SCIENCE AND TECHNOLOGYIN INTERNATIONAL DEVELOPMENT pptx
... Academy of Sciences to secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute acts under the responsibility ... setting the stage for another swing of the pendulum back to the latter as a result of disappointments with the results of diffuse grassroots investments of the 1970s In the early 1980s the USAID ... of Sciences, the National Academy of Engineering, and the Institute of Medicine The members of the committee responsible for the report were chosen for their special competences and with regard...
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Báo cáo khoa học: The role of helix 8 and of the cytosolic C-termini in the internalization and signal transduction of B1 and B2 bradykinin receptors potx
... patterns of B2wt and of B1 ⁄ B2 chimeras reflect their agonist-inducible internalization The segment between the NPXXY motif and the conserved cysteine represents one of the regions with the highest ... influences the formation of a helical structure These authors proposed that activation of the receptor, and subsequently of the G protein, leads to a change in the environment of helix resulting in the ... to enhance their adherence Expression vectors The sequence of the human B2wt starting with the third encoded methionine [9], the sequence of the human B1wt, truncations and chimeras of both were...
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Role of an electrolyte and substrate on the stability of porous silicon
... structure of PS leads to an enormous increase in surface area and the presence of large number of unpaired bonds at the surface which alter the surface recombination rates and consequently the PL ... The photochemical etching method with H2O2 solution does not generate a toxic material unlike in the case of HNO3 [11] Moreover, the addition of H2O2 to the etching mixture raises the pH of the ... cmÀ2) Decay of PL intensity is a good indication of the stability of porous silicon particularly of the surface bond configurations [3,16] In Fig 4(A), decay of the PL intensity at the peak wavelength...
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Báo cáo khoa học: Role of glutaredoxin 2 and cytosolic thioredoxins in cysteinyl-based redox modification of the 20S proteasome docx
... architecture of Grx2 consists of a four-stranded, mixed b-sheet and five a-helices The b-sheet forms the central core of the protein, with helices and located on one side of the sheet and helices 2, and ... spectrophotometrically by measuring the reduction of 0.5 mm HED in the presence of 0.5 mm GSH, 0.1 mm NADPH and 0.3 UÆmL)1 GR at 37 °C, and following the disappearance of NADPH at 340 nm All of the experiments with ... LC and HC, light and heavy chains of IgG immunoglobulin forms (cytosolic and mitochondrial matrix) [34], as the same band was seen in the anti-ubiquitin blot (Fig 7, anti-Ub) Blotting of the...
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Báo cáo khoa học: The role of residues R97 and Y331 in modulating the pH optimum of an insect b-glycosidase of family 1 pdf
... As the pKa values of the catalytic residues determine the pH optima, the ionization constants (pKa) of the catalytic glutamates (E187 and E399) in the ES complex and in the free enzyme (E) of ... the expression of the recombinant b-glycosidases Lysis of induced bacteria Fig Schematic representation of the Sfbgly50 active site E399 is the nucleophile and E187 is the proton donor Y331 and ... b-glucosidase affected the rate constant of the glycosylation step and also changed the enzyme pH optimum [14] Despite that, the effect of the tyrosine on the pKa values of the b-glycosidase catalytic glutamates...
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Báo cáo khoa học: Dissecting the role of protein–protein and protein–nucleic acid interactions in MS2 bacteriophage stability potx
... urea-induced and GdnHCl-induced changes in the secondary structure of the proteins, we analyzed the UV CD spectra of MS2 and VLPs in the absence and presence of 5.0 m and 9.0 m urea and 3.5 m and 5.0 ... determined the effects on stability of genetic fusion of the two subunits of the dlFG dimer using the variant named 2CTdlFG, which takes advantage of the physical proximity of the N-terminus and C-termius ... Effect of pressure on the coat protein in the presence of bis-ANS for (n) dlFG and (e) sc-dlFG and in the absence of the probe for (m) dlFG and (r) sc-dlFG, was analyzed at room temperature The...
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the role of labour mobility and informal networks for knowledge transfer
... for explaining the determinants of economic growth The focus on labor and capital as the primary factors of production, and the general exclusion or trivialization of the role of knowledge, was ... skilled labor, and technology The neo-technology theories focused on the role of R&D and the creation of new economic knowledge in shaping the comparative advantage and flows of foreign direct ... function of the number and concentration of permanent links 199 Dispersion as a function of the number and concentration of permanent links 200 Expertise as a function of the number and concentration...
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aging of the genome the dual role of dna in life and death mar 2007
... selection and Watson and Crick’s discovery of the molecular structure of DNA The grand understanding of the logic of life would prove equally important for understanding its demise: the logic of aging ... together, whereas the farther away they are from each other, the more chance of their INTRODUCTION being separated by the process of crossing over The Morgan is now the unit of measurement of ... mismatch at the third position of each triplet With the evolutionary synthesis and the new understanding of its underlying molecular principles, the pursuit of the origin and perpetuation of life...
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