the lord of the rings the return of the king
Báo cáo khoa học: Interactions of HIPPI, a molecular partner of Huntingtin interacting protein HIP1, with the specific motif present at the putative promoter sequence of the caspase-1, caspase-8 and caspase-10 genes pdf
... at the last base, G to A, abolished the interaction of HIPPI, so the last motif would notinteract with HIPPI. The other two motifs might be the target of HIPPI. In the upstream sequence of the Table ... positions of the motifs are indicatedby distance from the transcription start site (TSS). The position upstream of the TSS of any gene is denotedby ‘–’ followed by the distance from the TSS. In the caspase-8 ... confirmed the in vitro resultthat mutation of the motif abolished the binding of HIPPI to the specific sequence of the caspase-1 geneupstream sequence, and the increased expression of caspase-1...
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Báo cáo khoa học: Dissociation/association properties of a dodecameric cyclomaltodextrinase Effects of pH and salt concentration on the oligomeric state pot
... in the presence of KCl.Considering also the 3D structure of CDase I-5, the analysis of the quaternary state of CDase I-5 revealedFig. 8. Fluorescence spectra of CDase I-5. (A) - - - -, the ... the adjacentmonomer, of which G538 forms a hydrogen bond to the carbonyl oxygen of M51. Two residues at the N-terminus (H49 and H89) of a subunit were locatedclose to the C-domain of the other ... either in the secondarystructure of the protein according to far-UV CDdata or in the size of the protein determined by size-exclusion HPLC. They suggested that the changemight occur either...
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Báo cáo Y học: Introducing Wilson disease mutations into the zinc-transporting P-type ATPase ofEscherichia coli The mutation P634L in theÔhingeÕ motif (GDGXNDXP) perturbs the formation of the E2P state pdf
... than the wild-type both in the absence a nd in the p resence of Fig. 3. Normalized zinc-dependent ATPase activity of the wild-type andmutated enzymes. TheATPaseactivity(percentageoftheactivityofthewild-type) ... correspond-ingtoH475QinZntA)hasbeenshowntoresultinmislocalization of t he WD ATPase in the endoplasmicreticulum [24]. This trafficking defect as well the difficulty of producing enough of mutant protein has complicated the attempts to study the roles of the ... The effect of 30 lMZn2+on the Pi-phosphorylation of the wild-type and the P401Lenzymes (gray columns). Note that the maximal phosphorylation of the P401L mutant is only 8% of the wild-type...
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Báo cáo khoa học: Internalization of the human CRF receptor 1 is independent of classical phosphorylation sites and of b-arrestin 1 recruitment potx
... with the Substance P receptor [25]. Detachment of the cells from the surface of the culture dish could r eflectdisassembly of the actin cytoskeleton in the me mbraneregions as a consequence of ... both the cAMP and the PLC pathway [22], the second messengerproduct of either or both of these pathways couldbe invo lved in agonist-stimulated internalization of thisreceptor. The effect of ... f125I-labelled sauvagine could be observedin the presence of any of these inhibitors. These findingsindicate that neither the activation of PKA nor the activation of PKC is necessary for agonist-induced...
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báo cáo hóa học:" The occurrence of osteoarthritis at a minimum of ten years after reconstruction of the anterior cruciate ligament" pdf
... % of the patients B (3–5 mm) and in16% of the patients C (6–10 mm) stability.Looking at the osteoarthritis rate of the operated knee, 55% of the patients decreased one grade according to the Kellgren ... osteoar-thritis of 1 grade in 52% of the patients, 35% of the patients had an increase of 2 grades and 3% of the patientshad an increase of 3 grades. (Table 4, 5 and 6) 10 % of the patients had ... test). Thesepatients were considered at high risk of further knee injurydue to the degree of laxity and the desired level of activity[27]. In order to minimise the development of arthrofi-brosis,...
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báo cáo hóa học:" The psychological context of quality of life: a psychometric analysis of a novel idiographic measure of bladder cancer patients’ personal goals and concerns prior to surgery" pot
... major motivat ional theme as it demon-strates yet another dimension of the QOL AppraisalProfile and further helps e lucidate the nuances o f the profile. The major theme of reaching an event/milestone ... examination of patien t character-istics and quality of life, thematic content coding of responses to the Brief Quality of Life Appraisal Profile,examination of the relationship of goal attainment ... needed. Other patients c om-pleted the Quality of Life Appraisal Profile and othermeasures during the time that they were receiving neo-adjuvant chemotherapy. In order to see whether theseconfounders...
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Measurement of Color, Gloss, and Translucency of White Salted Noodles- Effects of Water Addition and Vacuum Mixing.pdf
... boiling time and the degree of starch swelling (Crosbie 1992). Accurate measurement of the color of boiled noodles necessitates the use of a method that minimizes the effect of variation on ... but expected to be largely independent of noodle thickness. These were considerations in the development of methods in the present study. The aims of the study were to develop new and improved ... Tests in Experiment 1 The distance along the visual analogue scales (VAS) for each of the six samples was measured, the results of the 32 panelists were combined, and the mean scores were compared...
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báo cáo hóa học:" En bloc excision and autogenous fibular reconstruction for aggressive giant cell tumor of distal radius: a report of 12 cases and review of literature" doc
... maintained all the records of the patients and followed them. All the authors read and approved the finalmanuscriptConflict of Interests The authors declare that they have no competing interests.Received: ... ulnar translocation in the treatment of giant-celltumors of the distal end of the radius. J Bone Joint Surg Am 1982,64(1):67-73.14. Smith RJ, Mankin HJ: Allograft replacement of distal radius for ... blocexcision of the distal radius and fibular autograft replacement. J BoneJoint Surg Br 1983, 65(5):618-20.26. Vander Griend RA, Funderburk CH: The treatment of giant-cell tumors of the distal part of...
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báo cáo hóa học:" En bloc excision and autogenous fibular reconstruction for aggressive giant cell tumor of distal radius: a report of 12 cases and review of literature" ppt
... maintained all the records of the patients and followed them. All the authors read and approved the finalmanuscriptConflict of Interests The authors declare that they have no competing interests.Received: ... graft in the treatment of aggressive bone tumours of the distal end of the radius. Arch Orthop Trauma Surg 1981, 98(4):285-7.13. Seradge H: Distal ulnar translocation in the treatment of giant-celltumors ... bonecementing for these grade II tumors. Of the 10 primarycases, initial preoperative biopsy confirmation of GCTwas done in 3 cases, all of which had a grade III tumorand there was a suspicion of a malignant...
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