the lord of the rings pdf return of the king
Đề tài " Higher composition laws IV: The parametrization of quintic rings " pdf
... and quartic rings by developing a theory of resolvent rings (quadratic resolvent rings in the case of cubic rings, and cubic resolvent rings in the case of quartic rings) . Carryingout the analogous ... is the meaning of the integers that occur as the entries of the matrices A1, . . . , A4? And what is the meaning of the ve quadratic mappings that arise as the ve 4ì4 sub-Pfaffians of A? A theory ... shows six of the twelve ways of connecting five points 1, . . . , 5 bya 5-cycle, the other six being the complements of these graphs in the completegraph on five vertices. The negation of the polynomial...
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Tài liệu Báo cáo khoa học: Structural characterization of Ca2+/CaM in complex with the phosphorylase kinase PhK5 peptide pdf
... againstFig. 4. (Top) Overlay of two spectra from the titration of Ca2+⁄ CaMwith PhK5 peptide. The red spectrum shows the position of peaksprior to the addition of PhK5 peptide. The blue spectrum shows ... 1.2 molar ratio of Ca2+⁄ CaM to PhK5had been reached. The inset shows an expanded view of the indi-cated area of the spectrum. (Bottom) An overlay of spectra from the titration of Ca2+⁄ CaM ... facilitated by the flexi-bility of the linker between the two domains as well asa certain degree of conformational flexibility in the two EF hand motifs of each CaM domain. The pres-ence of a relatively...
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Báo cáo khoa học: Interactions of HIPPI, a molecular partner of Huntingtin interacting protein HIP1, with the specific motif present at the putative promoter sequence of the caspase-1, caspase-8 and caspase-10 genes pdf
... at the last base, G to A, abolished the interaction of HIPPI, so the last motif would notinteract with HIPPI. The other two motifs might be the target of HIPPI. In the upstream sequence of the Table ... positions of the motifs are indicatedby distance from the transcription start site (TSS). The position upstream of the TSS of any gene is denotedby ‘–’ followed by the distance from the TSS. In the caspase-8 ... confirmed the in vitro resultthat mutation of the motif abolished the binding of HIPPI to the specific sequence of the caspase-1 geneupstream sequence, and the increased expression of caspase-1...
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Báo cáo Y học: Expression of the V-ATPase proteolipid subunit of Acetabularia acetabulum in a VMA3-deficient strain of Saccharomyces cerevisiae and study of its complementation pdf
... isoforms of the subunit a of mouse enzyme [22,23], four isoforms of the proteolipid subunit in Caenorhabditis elegans [24] andtwo isoforms of the subunit A in human osteoclastoma [25].Isoforms ... gene for one of the proteolipid subunits of V-ATPase. Expression of the cDNAs in the strain revealedthat four cDNAs from the six complemented the protontransport activity into the vacuole, ... assembly of the V-ATPasecomplex into the vacuolar membrane. They also reportedthat VMA11p and VMA16p exist at lower levels thanVma3p in the vacuolar membranes, although the exactmolar ratio of the...
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Báo cáo Y học: Introducing Wilson disease mutations into the zinc-transporting P-type ATPase ofEscherichia coli The mutation P634L in theÔhingeÕ motif (GDGXNDXP) perturbs the formation of the E2P state pdf
... than the wild-type both in the absence a nd in the p resence of Fig. 3. Normalized zinc-dependent ATPase activity of the wild-type andmutated enzymes. TheATPaseactivity(percentageoftheactivityofthewild-type) ... correspond-ingtoH475QinZntA)hasbeenshowntoresultinmislocalization of t he WD ATPase in the endoplasmicreticulum [24]. This trafficking defect as well the difficulty of producing enough of mutant protein has complicated the attempts to study the roles of the ... The effect of 30 lMZn2+on the Pi-phosphorylation of the wild-type and the P401Lenzymes (gray columns). Note that the maximal phosphorylation of the P401L mutant is only 8% of the wild-type...
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Báo cáo khoa học: Bioenergetic requirements of a Tat-dependent substrate in the halophilic archaeon Haloarcula hispanica pdf
... noted that the Dw normally forms only asmall part of the PMF in thylakoids. In bacteria,involvement of the PMF was first shown throughinhibition of translocation of the precursor of the Escherichia ... after 48 h of growth wastaken as the MIC. For incubation in the presence of suble-thal concentrations of ionophores, cells were grown in the presence of the various ionophores at 50% of the MIC.Pulse–chase ... that the SMF is maintainedmore stably in vesicles in the presence of ATP andNADH; in most haloarchaea, the main source of energy for the extrusion of sodium and accumulation of potassium is the...
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Báo cáo khoa học: The role of residues R97 and Y331 in modulating the pH optimum of an insect b-glycosidase of family 1 pdf
... because of the stabilizing effectprovided by R97, which is lacking in the mutant R97M.Hence, the DDG° is equal to the energy of the stabilizingeffect provided by R97. Thus, based on the DpKa of ... a major cause of the shift in the pKa of E399. Therefore, R97 facilitates the ionization of the catalytic nucleophile by stabilizing its charged state.Fig. 5. Effect of pH on the relative maximum ... alteration of the dielectric constant of the active site,although the deletion of the hydrogen bond between Y331and E399 is probably a major component of that pKaincrement. Based on the DpKaof...
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báo cáo hóa học:" The occurrence of osteoarthritis at a minimum of ten years after reconstruction of the anterior cruciate ligament" pdf
... % of the patients B (3–5 mm) and in16% of the patients C (6–10 mm) stability.Looking at the osteoarthritis rate of the operated knee, 55% of the patients decreased one grade according to the Kellgren ... osteoar-thritis of 1 grade in 52% of the patients, 35% of the patients had an increase of 2 grades and 3% of the patientshad an increase of 3 grades. (Table 4, 5 and 6) 10 % of the patients had ... test). Thesepatients were considered at high risk of further knee injurydue to the degree of laxity and the desired level of activity[27]. In order to minimise the development of arthrofi-brosis,...
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báo cáo hóa học:" The pivotal role of the intermediate fragment in initial operative treatment of olecranon fractures" pdf
... over the dorsal aspect of the distal humerus with a lateral curve around the radial aspect of the olecranon, and preparation of the softtissue envelope directly to the olecranon. Desimpaction of fracture ... Inorder t o restore the trochlear notch, temporary fixation of the intermediate fragment in anatomical position on the contour of the notch with respect to the distalaspect of the humerus was performed ... Reduction of the intermediate fragment was per-formed using a clamp between the distal and proximalfragment of the fracture into the interface between tro-chlear notch of the olecranon and the humerus...
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Báo cáo khoa học: Dissociation/association properties of a dodecameric cyclomaltodextrinase Effects of pH and salt concentration on the oligomeric state pot
... in the presence of KCl.Considering also the 3D structure of CDase I-5, the analysis of the quaternary state of CDase I-5 revealedFig. 8. Fluorescence spectra of CDase I-5. (A) - - - -, the ... the adjacentmonomer, of which G538 forms a hydrogen bond to the carbonyl oxygen of M51. Two residues at the N-terminus (H49 and H89) of a subunit were locatedclose to the C-domain of the other ... either in the secondarystructure of the protein according to far-UV CDdata or in the size of the protein determined by size-exclusion HPLC. They suggested that the changemight occur either...
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Báo cáo khoa học: Internalization of the human CRF receptor 1 is independent of classical phosphorylation sites and of b-arrestin 1 recruitment potx
... with the Substance P receptor [25]. Detachment of the cells from the surface of the culture dish could r eflectdisassembly of the actin cytoskeleton in the me mbraneregions as a consequence of ... both the cAMP and the PLC pathway [22], the second messengerproduct of either or both of these pathways couldbe invo lved in agonist-stimulated internalization of thisreceptor. The effect of ... f125I-labelled sauvagine could be observedin the presence of any of these inhibitors. These findingsindicate that neither the activation of PKA nor the activation of PKC is necessary for agonist-induced...
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báo cáo hóa học:" The psychological context of quality of life: a psychometric analysis of a novel idiographic measure of bladder cancer patients’ personal goals and concerns prior to surgery" pot
... major motivat ional theme as it demon-strates yet another dimension of the QOL AppraisalProfile and further helps e lucidate the nuances o f the profile. The major theme of reaching an event/milestone ... examination of patien t character-istics and quality of life, thematic content coding of responses to the Brief Quality of Life Appraisal Profile,examination of the relationship of goal attainment ... needed. Other patients c om-pleted the Quality of Life Appraisal Profile and othermeasures during the time that they were receiving neo-adjuvant chemotherapy. In order to see whether theseconfounders...
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Báo cáo hóa học: " Letter to the Editor Remarks on “On a Converse of Jensen’s Discrete Inequality” of S. Simic ´" doc
... between Theorems 2 and 8;thatis,in Theorem 2,thedifferentiability of a function φ is not emphasized which is used in the proof. Also, the proof of Theorem 2 is completely analogous to the proof of ... 6,page37. Therefore, w e willlook back only on case i of Theorem 1.By applying Theorem 3 to the function Fx, yx/y, we obtain the following result.Theorem 7. Suppo se that all the conditions of ... a discrete version of Theorem 8. It is obvious that the main results presented in 2 are special cases of results given in 3, Theorem 1, Corollary 1, Remark 2.Note that there is a difference...
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Báo cáo hóa học: "Research Article Existence of Solutions for a Class of Elliptic Systems in RN Involving the p x , q x -Laplacia" pptx
... υzdx.3.26Since the restriction operator is continuous, then un,n u, in W1,px0Br ì W1,qx0Br.Because of the compactness of Fr, the first expression on the right-hand side of the equationtends ... they apply the mountainpass theorem to get the nontrivial solutions of the the system.In 30, the author obtains the existence and multiplicity of solutions for the followingproblem:− div|∇u|px−2∇u∂F∂ux, ... and Mathematical Theory, vol. 1748 of Lecture Notes inMathematics, Springer, Berlin, Germany, 2000.13 V. V. Zhikov, “Averaging of functionals of the calculus of variations and elasticity theory,”...
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