... Acceleration ofthe cis–trans isomerization ofthe peptide results in the collapse of these resonances into a single set of peaks (D) Binding, but not isomerization, ofthe N-terminal peptide of PPWD1 ... with the oxygen of Gly551, the side-chain of Glu485 is nestled in a deep pocket ofthe enzyme (Fig 3B) An oxygen ofthe c-carboxyl group forms hydrogen bonds with the backbone amide nitrogen of ... described in the literature Further complicating the field of Cyp biology is the fact that many ofthe 17 Cyps annotated in the human genome have not been thoroughly studied in terms of either enzymatic...
... stand, or another form of coordinated operation Consequently, we shall not consider this element ofthe program in the analysis The fourth goal ofthe program is to improve the income ofthe taxi ... reflected in the parameter values (i.e., the emissions factors and the fuel economy ofthe new vehicles) On the basis ofthe changes introduced in the control scenario, data are needed on the incremental ... in models of so-called “rational scrappage”, where the optimal decision ofthe owner to keep or scrap the vehicle is based on the minimization ofthe present value ofthe costs from the two alternatives,...
... by consumers in the Eastern District ofTexas Rackspace has committed acts of patent infringement within the State ofTexas and, more particularly, within the Eastern District ofTexas PERSONALWEB ... products and offers its products and services in the United States, the State of Texas, and the Eastern District ofTexas Rackspace has purposefully and voluntarily sold infringing software and ... in the PersonalWeb Patent Field with the expectation that they will be purchased and used by consumers in the Eastern District ofTexas These infringing products and services have been and continue...
... a line of slope −1/r Then this is the line on which the starting point ofthe Hr -path must lie We call the line obtained in the above three steps the bisecting line BLh (T ) of φh (T ) The following ... symmetry will induce a bijective proof of N(i, j) = N(j, i), and then a bijective proof of Lemma 6.4 Proof of Theorem 6.3 Let G(m, n) be the number of K-paths starting at (−2m, −2m) and ending ... satisfies the following conditions The path P never goes above the diagonal The part of P that is to the left ofthe line x = is a V2 path the electronic journal of combinatorics 13 (2006), #R53 28 The...
... perturbation ofthe norm less than the value ofthe stability radius, not only the asymptotic stability is preserved, but also the index ofthe perturbed matrix pencil The latter property also implies the ... )} ε→+0 Proof The scheme ofthe proof of Theorem can be repeated without difficulties The only difference is that now the transformed matrices Aε , C ε contain O(ε) perturbations, too The uniform ... that the stability radius may be discontinuous as a function ofthe parameter Furthermore, as the parameter tends to zero, the stability radius ofthe parameterized system tends to the minimum of...
... observed in the active treatment groups when compared to the placebo (data not shown) These findings further demonstrate the safety of 5-Loxin® and Aflapin® in humans During the course ofthe 90-day ... ability scores as early as days after the start of treatment, and these indices continued to improve throughout the 90 days of treatment (Figure 2) After days, the 5-Loxin® treatment group exhibited ... [31] The pain subscale was the average ofthe first five questions of WOMAC and measured using the NU scale from ('no pain') to 100 ('extreme pain') for each question The stiffness subscale was the...
... facilitated by the overlap ofthe N lone pair with the lobe Figure Optimized geometries of various minima on the potential energy surface oftheofthe s* orbital proximate to the S atom, not the CH3SCH3/NMA ... interactions, but the E(2) values of all of them are only around 0.52 kcal molÀ1 The comparison ofthe complexes of NMA with CH3SH and CH3SCH3 indicates that the loss ofthe possibility of an SH···O ... The stability ofthe global minimum ofthe CH3SH/NMA heterodimer rests not on one, but on several of these elements The strongest component is an H-bond involving a methyl CH of CH3SH The O lone...
... transaction, there is a certain moment of time wherein the ownership ofthe goods by the seller ceases and passes to the others and that ofthe buyer begins; that is called the transfer of title ... transfer of risk to goods during goods delivery It therefore draws most attention of both the seller and the buyer during their transaction from the place ofthe Seller to the place ofthe Buyer ... “This contract will become binding on the parties as ofthe date the Seller signs it, provided that the Seller does not alter, delete, or add to the terms ofthe contract and provided that the...
... water, the expansion of which provokes the formation of micro air bubbles The particles, that are likely to decant, accumulate at the bottom ofthe truncated part and are then evacuated towards the ... other petroleum products resold to the Ivorian Refining Company (SIR) The hydroskimming units and the DHC are the main producers of waste water Figure describes the treating process flow ofthe ... truncated base where they are evacuated 8) The observation tank The treated water flows through the siphoned partitions ofthe flotator and, under the influence of gravity, goes down in the equilibrium...
... Interpretation ofthe Convention D Interpretation ofthe contract; usages E Form ofthe contract Part Two Formation ofthe contract Part Three Sale of goods A Obligations ofthe seller B Obligations ofthe ... by the buyer from the time the goods were handed over to the carrier who issued the documents embodying the contract of carriage Nevertheless, if at the time ofthe conclusion ofthe contract of ... provision ofthe contract for the settlement of disputes or any other provision ofthe contract governing the rights and obligations ofthe parties consequent upon the avoidance ofthe contract...
... reproduces the matter without the manner, or the content without the form ofthe original The advantage of this type of translation is that the text in TL sounds more natural On the contrary, the disadvantage ... Types of equivalence II The technical translation III An overview of trade contract The notion of trade contract The center role ofthe contract in trade Chapter II: A study on the translation of ... interests ofthe parties to the contract but also the risks expected to happen in the future to be able to adjust the terms of contract suit landscape practices and rules of law More so, the role of contracts...
... with EGFP either at the C-terminus or the N-terminus By contrast, expression of EGFP alone induced neither caspase nor PARP cleavage Because of differences in the cytotoxicity ofthe fused products ... used as a control of sample loadings Discussion In the present work, the cytotoxic properties ofthe minor structural proteins (VP2 and VP3) ofthe MPyV were studied in the absence of other virus ... levels of apoptotic markers during the late stages of MPyV infection However, comparison ofthe levels of apoptotic markers and cytotoxicity during the replication of wt MPyV, and replication of the...
... the final evaluation ofthe kinetic parameters in the presence of stearate Evaluation of kinetic parameters Fig Comparison of three models for the catalytic action of plasmin in the presence of ... decrease of plasmin activity in the course ofthe assay in the presence of stearate (Table 1) The good fit of Model III progress curves to the experimental data supports the concept that in the presence ... which the initial reaction rate is half ofthe in which E ¢ indicates the inactive form ofthe enzyme, and J1, J2 and J3 are the rate constants for inactivation ofthe respective forms ofthe enzyme...
... presence of H2O2 alone, a non-physiological condition We believe that the absence of direct evidence ofthe radical in the presence of cosubstrates limits the validity of extrapolating the model ... oxidize them [19] On the other hand, this fact does not represent proof ofthe presence of one or two oxidizing equivalents on the decay product of Cpd I The EPR spectrum of a spin-trapped radical ... each of these questions, we will propose a new hypothesis that describes an integrated vision ofthe catalytic mechanism of MPO and LPO A brief survey ofthe absorption features of MPO, LPO and their...
... plotting the ratio ofthe fitting functions of wild-type over mutant, either in the presence or in the absence of a Du, as shown in Fig 3C In the presence of a Du, the difference between the two ... in the case ofthe mutant The large difference relative to the wild-type can be best appreciated by taking the derivative ofthe fitting functions ofthe mutant and wild-type data and plotting their ... (extrapolating the fitting function when necessary) The ratios ofthe wild-type derivatives over the mutant, indicating the ratios ofthe ATP synthesis rates, are plotted for the experiments in the absence...
... For the summer data, the location of this minimum coincides with the maximum r2 value for the photochemically produced tracer species We interpret the location ofthe critical value of r2 as the ... function of (OC/EC)E for winter and summer Again, the critical point ofthe curves gives the representative value of (OC/EC)E for that time of year [64] The median value of (OC/EC)E determined for the ... further in the following section The primary emission ratios calculated in this section are averages over the sources impacting the air masses that were sampled during the course ofthe study They...
... antigenically distinct [10,11] 2360 The A domain of ClfA and FnBPA bind Fg at the C-terminus ofthe c-chain [7] The interaction between the A domain of ClfA and the c-chain of Fg has been studied in detail ... [15] They are located in the equivalent positions to the aforementioned residues P336 and Y338 of ClfA One ofthe objectives of this study was to determine the mechanism of Fg binding by the A ... protects the bacterium from the host immune system and promotes its spread from the site of infection to other tissues and organs ofthe host Indeed, FnBP-mediated invasion of endothelial and epithelial...
... segment and the other helix lines the boundary between the major domain and the N-terminus (Fig 1) Therefore, the formation ofthe third cluster may represent a key event ofthe final phase of folding, ... confirmed that the depletion ofthe cofactor does not have any effect on the dimeric assembly ofthe enzyme The sedimentation velocity Fig Schematic representation ofthe monomeric structure of eSHMT ... counteracts the effect ofthe mutations, stabilizing the dimeric form The stabilizing effect is even more pronounced if l-serine binds to the cofactor at the active site, as is evident in the case of the...