... abdomen These findings are comparable with the clinical presentation reported in other (3,9) children Abdominal pain and an abdominal mass, with or without hepatomegaly, is (11,12,13) the commonest ... 1) Imaging studies included plain abdominal films, ultrasound and CT scan of the abdomen In one of ten patients plain films showed calcification inthe right upper quadrant Ultrasound of the abdomen ... the cyst cavity (obliteration of the cavity by folding the cyst wall inside the cavity and suturing the outer surface layers to the bottom of the cavity to fix the folded cyst wall) All specimens...
... chemotherapy, including FOLFOX in 35 patients, FOLFIRI in 15, Avastin in 37 patients, and other biologics in 9, with patients receiving hepatic directed radiotherapy The extent of liver involvement was ... analysis and interpretation of data, involved in drafting the manuscript or revising it critically for important intellectual content RP have been involved in drafting the manuscript or revising it ... important intellectual content MR have been involved in drafting the manuscript or revising it critically for important intellectual content FS have been involved in drafting the manuscript or revising...
... protein that blocks the processing of sterol regulatory element-binding proteins (SREBPs) by binding to SREBP cleavage-activating protein, thus preventing the latter from escorting SREBPs to the ... Genes involved in fatty acid biosynthesis, such as Acacb, Acbd6 (acyl-CoA-binding domain containing 6), Scd2 (stearoyl-CoA desaturase 2) or associated genes, Sorbs3 (sorbin and SH3 domain containing ... prevented the harm caused by an HFD In addition, we found no significant alterations inthe levels of alanine aminotransferase, aspartate aminotransferase or creatinine kinase in either group...
... across cellular membranes and into the cytoplasm [3,4] The first step inthe intoxication process involves DT binding, via its B-subunit domain, to the heparin-binding epidermal growth factor-like ... translocation of toxin peptides in cell-free endosomes containing in vivo internalized DT The EN was isolated 15 after the administration of native DT and then suspended in 0.15 M KCl containing mM MgCl2 ... gel) for the indicated times The incubation mixtures were then analyzed by reducing SDS ⁄ PAGE followed by Coomassie Brilliant Blue staining Arrows to the right indicate the mobilities of intact...
... poorly diff neuroendocrine carcinoma Tức : poorly diff neuroendocrine tumor từ cecum chạy tới gan (2) Bây xác nhận neuroendocrine carcinoma chạy tới gan, chữa dùng chemotherapy agents mà thường ... chữa ung thư thấy phổi, tức dùng combination Carboplatin etoposide "first line" - Kinh nghiệm "small cell cancer of the lung" (tức ung thư thuộc loại neuroendocrine tumor) cho thấy bnhân : lúc đầu ... thư, lại neuroendocrine tumor (ung thư từ colon, vú : thường phải adenocarcinoma) Khi thấy neuroendocrine tumor, tách (a) well differentiated, hay moderately differentiated: carcinoid tumor hay pancreatic...
... reducing the frequency of complications during and after the transplantation [7,11,36] The goal of this study was to demonstrate theliver imaging of Yucatan micropigs using the MDCT for assessing ... was injected to abolish the autonomic respiration through the line installed in an ear vein The micropigs were endotracheally intubated and ventilated (250 ml, frequency 10 to 12 per min) during ... (3D) program installed (Rapidia; INFINITT, Korea) Individual volume data were loaded into the 3D program, and the data were reformed into routine 3D images, which included maximum intensity projection...
... chemotherapy in August 2001, radiation therapy was administered to the right breast In January 2002, after CT, the patient presented with a single metastatic lesion (diameter, 1.4 cm) inthe right ... define a time point beyond which trastuzumab might not offer additional benefit Furthermore, evidence inthe literature supports the idea that continuing anticancer treatments as maintenance therapy ... metastatic lesion intheliver taken in 2002 Page of Figure Magnetic resonance imaging scan taken in 2003 The hepatic lesion has disappeared of trastuzumab treatment during pregnancy and the chance...
... heart failure worldwide Heart failure is primarily a disease of the elderly, and the prevalence of chronic heart failure increases with advancing age Currently, chronic heart failure is the most ... clinically indistinguishable from diastolic heart failure It is important to identify patients who have systolic heart failure because they may be eligible for surgical therapy The important information ... heart failure ranges from 5% to 15%, and admission rate for recurrent heart failure is 50% within the first months [1–4] The remaining 50% to 70% of patients present with systolic heart failure...
... better understanding of the anatomy and pathophysiology of heart failureThe failing heart beats at more than 120,000 beats per day, pumping more than 6,000 L of blood against an increased systemic ... balloon angioplasty and stents In turn coronary intervention rates will fall because of public health initiatives on diet and smoking together with the widespread use of statins Stent graft technology ... patients who have heart failure, other surgical options may soon provide symptomatic relief for the majority The demand for treatment emerges from an increasingly elderly heart failure population...
... with borderline cardiac index and a blood pressure of 110/70 mm Hg Over the next hours the blood pressure remains acceptable on inotropic support but the urine output dwindles and the ankles are ... and a borderline transvalvular gradient [4] Intraoperative myocardial injury remains prevalent inthe increasingly elderly surgical population because tolerance to ischemia is reduced in aged myocardium ... myocardial failure [1] Inthe PURSUIT trial, which randomized patients who had coronary bypass and unstable angina to a glycoprotein IIb/IIIa inhibitor or placebo, the 7-day mortality or myocardial infarction...
... evolves Inthe first minute, contractile dysfunction within the ischemic zone results from sarcomere deterioration Active systolic shortening progresses to passive lengthening Within 20 minutes ... result of emerging knowledge, new procedures, and technical advances This article addresses the pathophysiology, the treatment options, and their rationale inthe setting of life-threatening AMI and ... and arrhythmia The death rate from AMI has fallen by nearly 30% since the 1990s, with in- hospital mortality from AMI falling from 11.2% to 9.4% from 1900 to 1999 [3] Improvements in mortality and...
... hibernating myocardium) and that which is replaced by fibrosis and scarring after previous myocardial infarction There is increasing evidence that chronic LV dysfunction resulting from hibernating ... Heart Failure Clin (2007) 211–228 Revascularization in Heart Failure: Coronary Bypass or Percutaneous Coronary Intervention? Sorin V Pusca, MD, John D Puskas, MD* Emory University School of Medicine, ... disease (CAD) is currently the single most common cause of heart failurein adults [1] The prognosis of patients who have severe CAD and left ventricular (LV) dysfunction remains poor despite new medical...
... connect the myocytes in a complex array of fibers forming the 3-D architecture of the wall and coordinating the delivery of forces generated by myocytes These forces are important determinants ... reciprocal of internal radius) at the apical level that creates a high local tension The increase in tension plays a key role in activating complex neurohormonal mechanisms, including an increase in angiotensin ... accounts for the twisting effect of the apex that optimizes the ejection of blood into the aortic vessel The elliptic shape enhances blood flow at thein ow and outflow tract When disease alters the shape...
... chlorpromazine decreases SOD enzyme activity inthe brain and in erythrocytes [61], the effects intheliver are not known The interleukin receptor antagonist (IL1RN) gene inhibits the activities of interleukin ... chlorpromazine has been shown to increase insulin sensitivity intheliver by attenuating insulin and leptin signaling pathways [55] It is interesting that one of the main side effects of atypical Page ... causing an accumulation of fatty acids intheliver [10] However, certain typical APs, including chlorpromazine and haloperidol, may also decrease the activity of CYP450 isozymes inthe liver...
... amount of viable but hibernating myocardium is present We should obtain the first results of trials in 2007 Revascularization is not discussed further in this manuscript The initial enthusiasm for skeletal ... transplantation into the failing myocardium has been tempered by experience There is now considerable uncertainty whether this approach provides worthwhile benefits [11,12] Hopefully, refinements inthe technologic ... erythropoietin-stimulating peptides when not due to specific haematinic deficiency may also improve symptoms, although the data are not robust [5] Withdrawal of nonsteroidal anti -in ammatory drugs, including...
... method to save the lives of patients who are facing imminent death [17] The development of cardiac assist devices has made much progress within the last 10 years Inthe 1980s, mainly paracorporeal ... that allows the heart a period of relative rest in which functional improvement may be achieved by interrupting the vicious circle of increasing wall tension and functional impairment The hearts ... available; however, inthe 1990s, the partly implantable and fully implantable pulsatile cardiac support systems emerged and played an increasing role (Fig 1) [18,19] Then, in 1998, the first rotary...
... ‘‘destination treatment’’ or ‘‘lifetime therapy’’ are used to describe the intention at the moment of insertion of the device: that it should remain in place for the life of the patient and that there ... LVADs are an engineering triumph but raise critical issues regarding how and when they should be used This problem has been exacerbated by the decline inthe number of patients undergoing transplantation, ... severe heart failure has increased in complexity, requiring greater skills and finer judgment from the physician and surgeon New drugs have emerged, the expertise of physicians in using these drugs...