the influence of discourse
Báo cáo khoa học: The influence of heterodimer partner ultraspiracle/retinoid X receptor on the function of ecdysone receptor pot
... byEcR in the presence of ligand was maximum in the case of HsRXR and minimum in the case of the Hs–LmRXR chimera, and LmRXR was betweenthese two (Fig. 9). These data suggest that the EcRand ... beenused in the place of USP in all EcR gene switchesdeveloped to date. One of the major limitations of cur-rent versions of EcR gene switches is the requirement of micromolar concentrations of ligand ... concentrations of ligandsfor the transactivation of genes and functions wellin vivo. The RXR chimeras containing most of HsRXR and helix 9 and the loops on either side of helix 9 from HsRXR or mutants of...
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Báo cáo khoa học: The influence of cold shock proteins on transcription and translation studied in cell-free model systems pdf
... critically dependon the other free parameters of the model, a property of the used function. On the other hand, this meansthat the other parameters following from the fit of the data cannot be ... to the inherentexperimental errors of our assay. However, the expres-sion of CAT under the influence of any of the threeused CSPs resulted in a significant, dramatic decrease of protein synthesis ... terms of codon usage and minimization of possible RNA secondary structures. We verified the difference in the thermodynamics of the RNA secon-dary structures by predicting the free energy of the RNA...
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Báo cáo khoa học: The influence of cholesterol on the interaction of HIV gp41 membrane proximal region-derived peptides with lipid bilayers potx
... mayreach the point where all of the membrane is homoge-neous. The MPRP-C is insensitive to the cholesterolcontent in the membrane, which is in agreement with the insensitivity of the peptide to the ... about the interaction of peptides with large unilamellar vesicles(LUV). The fluorescence quantum yield is dependent on the polarity of the microenvironment of the Trp resi-dues, as well as on the ... The membrane interaction behaviour of MPRP-Cand MPRP-I is independent of the membrane phasebut not of the presence of charged lipids. Cholesteroldoes not reduce the extent of or potentiate...
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Báo cáo khoa học: The influence of temperature and osmolyte on the catalytic cycle of cytochrome c oxidase ppt
... [15]. The second electron rereduces CuAthereby forming the initial two-electron reduced oxidase. In the absence of oxygen or the presence of CO, there is probably a two-electron reduction of the ... other factors. None-theless, catalytic activity is still one of the few characteristicsthat reflect the actual role of the oxidase in the tissues.What is that role? The oxidase catalyzes the ... increase the viscosity of the medium; ifthere are large conformational changes that occur in the oxidase during the catalytic cycle, these would be influencedby the increased viscosity. Certainly, there...
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Báo cáo hóa học: " Research Article Removing the Influence of Shimmer in the Calculation of Harmonics-To-Noise Ratios Using Ensemble-Averages in Voice Signals" docx
... with the adjacent pulse, and the correlation should6 EURASIP Journal on Advances in Signal Processingbe lower. The evaluation of the influence of jitter (as well of other levels of noise and their ... shimmer increases. On the other hand, the summation of tails in one pulse isnot completely uncorrelated with the summation of tails in the other. For this reason, the estimation of relative pulseamplitudes, ... used in the synthesis. The results for the different methods facing both noisetypes are shown in Figure 1, and the discussion below isfirst centered in the AWGN and later in the effect of the correlation...
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Tài liệu Báo cáo khoa học: Influence of modulated structural dynamics on the kinetics of a-chymotrypsin catalysis Insights through chemical glycosylation, molecular dynamics and domain motion analysis pptx
... concerning the influence of glycosylation on the protein biophysical properties but also support the hypothesis that fora-CT the global structural dynamics directly influence the kinetics of enzyme ... some of these phenomena maybe interconnected within the catalytic mechanism of the enzyme.Structural insights into the mechanochemicalnature of a-CT catalysisA more detailed analysis of the influence ... within a cutoff distance (rc¼ 6.0 A˚). The dynamics of the resulting network are then defined by the Ni · Nj Kir-chhoff connectivity matrix of interresidue contacts (G)where the off diagonal...
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Báo cáo khoa học: Influence of divalent cations on the structural thermostability and thermal inactivation kinetics of class II xylose isomerases pdf
... the similar bio-chemical and thermostability properties of theseenzymes [7]. Comparisons between the structures of the most thermostable class I XIs from Thermus caldo-philus and Thermus thermophilus ... presence of various metal concen-trations and metal combinations was determined.Figure 7 shows the inactivation courses of apo-TNXIand of TNXI in the presence of 5 mm concentrations of each of the ... hyperthermophiles are intrinsically ther-mostable and thermoactive, with optimal temperatures of activity often in excess of 100 °C [1]. Studies focus-ing on the molecular basis for the thermostability...
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Báo cáo khoa học: Weak organic acid stress inhibits aromatic amino acid uptake by yeast, causing a strong influence of amino acid auxotrophies on the phenotypes of membrane transporter mutants ppt
... lowers the intracellular levels of benzoate and fluoresceinby catalysing an active efflux of these compounds from the cell [2,4]. The inhibitory effects of different organic acids oncells of the ... from the Euroscarf collec-tion that lack specific enzymes of the aromatic amino acidbiosynthetic pathway. These were then tested for theirsensitivities to both acetate and sorbate. Growth of the wild-type ... several of the enzymes of aromaticamino acid biosynthesis therefore hypersensitize yeast toweak organic acid stress.We also investigated the growth of this same series of strains after they had...
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Tài liệu Influence of future air pollution mitigation strategies on total aerosol radiative forcing pdf
... wellas changes in the aerosol and oxidant composition. The influence of changes in the 15aerosol composition are reflected in the changes of the microphysical aging time of BCand POM. The microphysical ... biomassburning.15 The emissions are detailed for the different sectors in Table 1. The evolution of the aerosol emissions for the different experiments are discussed together with the resulting changes in the ... among the aerosol modes, condensation of gas-phasesulfuric acid onto the aerosol surface, the formation of new particles by binary nucle-ation of sulfate, and the water uptake depending on the thermodynamic...
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Báo cáo khoa học: Influence of inflammation-related changes on conformational characteristics of HLA-B27 subtypes as detected by IR spectroscopy potx
... either from the intensity ⁄ temperature plot of the b-sheet band of b2m at 1592 cm)1or from the frequency ⁄ temperature changes of the tyrosine ring vibration of the HC at 1514 cm)1 of the ... are due to different packing of the protein chainsin crystallo. A comparison of the X-ray structuresrevealed, however, that the structures of the HC and of b2m of the two subtypes appear nearly ... irrespective of the sequence of the bound peptide and itsbinding mode. They might thus influence antigenic properties of the respec-tive HLA-B27 subtype. Furthermore, a decrease in the pH from...
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- especially in developed countries chronic diseases disproportionately affect the older segment of the population
- the regulation mechanism of the systems is programmed in each component
- this book provides information on the clinical relevance of blood groups and on the importance of blood group antibodies in transfusion medicine in particular
- influence of polymer additive
- influence of phenolic group content
- the intonational structuring of discourse
- interpreting ellipsis in the context of discourse inference
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