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the importance of innate defences in forming barriers to or conversely promoting mucosal hiv infection

Báo cáo y học:

Báo cáo y học: " Innate immunity against HIV: a priority target for HIV prevention research" ppt

Báo cáo khoa học

... widespread viral dissemination takes place (Figure 1) a The importance of innate defences in forming barriers to or conversely promoting mucosal HIV infection The observation that following heterosexual ... Administration of innate effector molecules or factors that modulate the activity of innate subsets in microbicides or as therapeutic agents The simplest method of employing innate defences for ... pathogenesis during HIV infection, to determine the utility of targeting these cells in vaccine design Explore the effects of persisting vaccine vectors on local and/ or systemic innate responses ¬ Borrow...
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To Cut or Not to Cut? That is the (Central Bank’s) Question In Search of the Neutral Interest Rate in Latin America pdf

To Cut or Not to Cut? That is the (Central Bank’s) Question In Search of the Neutral Interest Rate in Latin America pdf

Ngân hàng - Tín dụng

... Quantitative easing: Widen the definition of securities To improve access to allowable for temporary repos and short-term funding for Widening the definition of allowed private sector non-financial financial ... Decrease the ratio to percent Increase the ratio to percent Increase the ratio to percent Increase the ratio to 8.5 percent Increase the ratio to percent Increase the ratio to 9.5 percent Increase ... credibility due to recent changes in its Board of Directors  Widespread financial indexation There is strong inertia due to the indexation of financial contracts to the overnight interest rate (World Bank,...
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cash cycle factors that influence the desired level of cash optimal cash inventories

cash cycle factors that influence the desired level of cash optimal cash inventories

Tài chính doanh nghiệp

... Inventory…a tool is cash budget analysis and 2) how to finance ST assets…a tool is performing credit analysis Managing WC involves determing: • How much to invest in CA? - CA vs FA - Nature of ... electronically sohold lots until the= forgo investing zero) hold lotsof cash =cash balance is in M/S it waits of cash forgo investing in M/S and earning interest and earning interest Optimal Cash Balance ... want a ‘safety stock’ of cash The Miller - Orr Model • The Miller-Orr Model provides a formula for determining the optimum cash balance (Z), the point at which to sell securities to raise cash...
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A survey of factors that demotivate first-year non-major students in learning English at University of Labor and Social Affairs

A survey of factors that demotivate first-year non-major students in learning English at University of Labor and Social Affairs

Thạc sĩ - Cao học

... strongest influence on motivation was not the presence of motivators in the classroom, but the absence of demotivators” (Christophel &Gorham, 1995) At the beginning of the semester, the absence of context ... and more importantly, they will lose their interest in learning lessons Realizing the influence of this factor, the teacher needs to provide the amount of background information available and to ... among factors (A=Group of student-related factors, B= Group of teacher-related factors, C=Group of factors relating to learning conditions; A1-A4=Factors in Group A, B1-B4= Factors in group B,...
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An investigation into factors that hinder the participation of Univeristy students in English speaking lessons = khảo sát các yếu tố hạn chế sự tham gia của sin.PDF

An investigation into factors that hinder the participation of Univeristy students in English speaking lessons = khảo sát các yếu tố hạn chế sự tham gia của sin.PDF

Sư phạm

... finding out the factors including teachers‟ factors, students‟ factors and learning – teaching conditions hindering students‟ participation in classroom activities 2 Methods of the Study In the ... may involve expressing ideas, wishes or opinions, negotiating or solving problems, or establishing or maintaining social relationships Speaking is the process of building and sharing meaning ... participation in speaking activities 100% of the teachers and 52% of the students agrred that teachers‟ boring teaching was one of the most important factors hindering students‟ participation in speaking...
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An investigation into factors that hinder the participation of Univeristy students in English speaking lessons = khảo sát các yếu tố hạn chế sự tham gia của sin20150227.PDF

An investigation into factors that hinder the participation of Univeristy students in English speaking lessons = khảo sát các yếu tố hạn chế sự tham gia của sin20150227.PDF

Sư phạm

... on finding out the factors including teachers‟ factors, students‟ factors and learning – teaching conditions hindering students‟ participation in classroom activities Methods of the Study In the ... 100% of the teachers and 52% of the students agrred that teachers‟ boring teaching was one of the most important factors hindering students‟ participation in speaking lessons According to them, ... students 3.2.8 Forming a habit of speaking English in the class In order to increase the students‟ time of speaking English in the class, the teachers should form a habit of using English This...
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Báo cáo khoa học:

Báo cáo khoa học: "Alteration of pharmacokinetics of oxytetracycline following oral administration of Piper longum in hens" ppsx

Báo cáo khoa học

... ytilibitpecsus lavretni egasoD msinagroorciM seitilibitpecsus tnereffid fo smsinagroorcim rof slavretni egasod suoirav ta sdrib yrtluop ni mugnol repiP fo noitartsinimda laro gniwollof deniatbo seulav citenikocamrahp ... dohtem cirtemotohportceps yb ti ni tnetnoc enirepip fo ecneserp eht rof dezidradnats saw mugnol P deyassa llit C 02− ta nezorf erew selpmas ehT noitarapes amsalp rof setunim 01 rof mpr 000,3 ta ... desu saw drib hcae rof enilcycartetyxo fo eliforp emit-noitartnecnoc amsalp ehT ]2[ msinagroorcim tset eht sa )87711 CCTA( sediocym rav suerec sullicaB gnisu euqinhcet yassa laiborcim gnisu yb denimreted...
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Báo cáo khoa học:

Báo cáo khoa học: " A predictive model for the level of sIgA based on IgG levels following the oral administration of antigens expressed in Sacchromyces cerevisiae" pdf

Báo cáo khoa học

... ygoloibohtap :eainomuenporuelp sullicabonitcA RP ,drofgnaL ,SJ llorK ,NA tforcyR ,JA keddeB ,JB naheehS ,H nosnaJ ,TJ essoB 6114-0114 ,95 ,1991 nummI tcefnI epytores eainomuenporuelp sullicabonitcA ... htiw dedivorp erew slamina llA )aeroK ,ytisrevinU lanoitaN luoeS( slamina yrotarobal fo esu dna erac eht rof snoitaluger dna ycilop gniwollof yduts siht tuohguorht desu erew )aeroK ,ytisrevinU lanoitaN ... no snoitcefni morf tsoh eht gnitcetorp rof laitnesse era yltnednepedni gnitca meht fo htoB ]51 ,41[ desopxe yltnatsnoc si ti hcihw ot snegitna ngierof eht ot gnidnopser rof smsinahcem evitpada...
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Báo cáo y học:

Báo cáo y học: "In-vivo evaluation of simultaneous administration of incompatible drugs in a central venous catheter with a decreased port to port distance" pps

Báo cáo khoa học

... space, the proximal lumen may be close to the site of entry of the vein or even outside the vein This increases the possibility of extravasation if the catheter is accidentally dislodged or is ... In the final phase, the phenytoin was administered through the proximal lumen and the TPN through the medial lumen The same methodology was repeated on the opposite limb using the control catheter ... possible patients The shorter port to port distance and catheter length may help to minimize the chance that one of the lumens might be positioned improperly, resulting in the potential for extravascular...
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Báo cáo khoa học: High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein1 pot

Báo cáo khoa học: High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein1 pot

Báo cáo khoa học

... interaction domain and the nuclear receptor co-activator-binding domain, reside in the disordered regions of the protein [4] In the case of Ste5, the scaffold protein that binds several kinases of the MAPK ... decided to study this feature in detail to gain further insight into the possible importance of disorder in Caskin1 function and the class of scaffolds in general The collection of scaffold proteins ... characterization of Caskin1 fragments As described in the introductory paragraphs, the N-terminal half of Caskin1 contains a number of well-known domains involved in protein–protein interaction, such as the...
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Construction of neurotoxin database and screening for potential therapeutic agents

Construction of neurotoxin database and screening for potential therapeutic agents

Tổng hợp

... α-neurotoxins can be classified into short-chain, long-chain, kappa and weak neurotoxins Although the primary target of all these categories of the three-finger neurotoxins appears to be the muscle-type ... single-residue insertion in position 52 (Fiordalisi, 1994) These toxins have shorter carboxyl-terminal tail than any other long chain αneurotoxins κ-Neurotoxins bind with high affinity to the α3-containing ... terminal The MII domains of all five subunits contribute to the formation of the cation channel pore (Figures 1.4 A & B) In vertebrates, the combinatorial assembly of various nicotinic receptor...
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Báo cáo khoa học: Assessment of telomere length and factors that contribute to its stability potx

Báo cáo khoa học: Assessment of telomere length and factors that contribute to its stability potx

Báo cáo khoa học

... the sample to that of the internal control, normalized to the DNA values at the G0/G1 phase The use of an internal control (e.g 1301 cell line) is important to monitor the accuracy of the procedure ... on the staining and intensity of the fluorescent signal Thus, the choice of the flow cytometer depends on factors Ó FEBS 2003 such as type of sample (cell/tissue), type of information required, the ... present in more than 100 copies per chromosome and is associated with the entire length of the telomere Inhibition of TRF2 binding or blocking of the binding sites has been reported to result in a...
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Factors that Influence Successful Start-Up of Home Visiting Sites pptx

Factors that Influence Successful Start-Up of Home Visiting Sites pptx

Khoa học xã hội

... present the findings regarding the factors that promoted or were barriers to implementing the program in the fifth section The final section offers some conclusions The Context of the First Born® ... admitted to some of the same challenges that these two sites encountered in terms of achieving and maintaining fidelity Nearly all of the factors contributing to challenges in maintaining fidelity ... across sites in order to consider that factor a contributor to the successful start-up or an obstacle to successful start-up We consider a factor to be supported as a contributor to a first-year...
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Báo cáo y học:

Báo cáo y học: "“I could cry, the amount of shoes I can’t get into": A qualitative exploration of the factors that influence retail footwear selection in women with rheumatoid arthritis" pdf

Báo cáo khoa học

... accommodate insoles to provide therapeutic benefit and overall comfort “ the problem with having these sort of inserts [orthoses] is that I can’t get them into any other shoes other than the shoes they ... reported if orthoses were not worn because these devices did not fit into retail shoes; particularly as orthoses were found to be helpful in reducing pain Therefore not wearing orthoses both increased ... clinic within the south east of England Subjects were invited to participate on the basis that they met the criteria outlined in Table 1, established through reviewing their clinical records Of...
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Báo cáo y học:

Báo cáo y học: " Pruritus: a useful sign for predicting the haemodynamic changes that occur following administration of vancomycin" ppsx

Báo cáo khoa học

... haemodynamic profile was taken for each patient at the following time points: before the administration of vancomycin (time point 1); at 15 (time point 2) and 30 (time point 3) after the beginning of vancomycin ... conducted to investigate the haemodynamic changes that occur following the appearance of pruritus We therefore opted to administer vancomycin over a period of 30 in order to encourage appearance of the ... until the morning of the operation Premedication consisted of morphine (0.1 mg/kg) and scopolamine (0.005 mg/kg), administered intramuscularly hour before the patient entered the operating room...
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Báo cáo khoa học:

Báo cáo khoa học: "Factors that predict outcome of intensive care treatment in very elderly patients: a review" potx

Báo cáo khoa học

... prognostic factors should be taken into account in a prognostic model to support informed decision making Competing interests The author(s) declare that they have no competing interests Authors' contributions ... length of stay in intensive care units Ann Intern Med 1993, 118:753-761 27 Kaplan MH, Feinstein AR: The importance of classifying initial co-morbidity in evaluatin the outcome of diabetes mellitus ... adjusted for severity of illness, Acute Physiology Score, admission source, diagnosis and comorbidity These conclusions are in accordance with the findings of the SUPPORT study [4] In that study the...
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Báo cáo khoa học:

Báo cáo khoa học: "A Reactive oxygen species: toxic molecules or spark of life" docx

Báo cáo khoa học

... regulators of metabolic processes and part of the chemistry of life [10,11] Furthermore, evidence of oxidative injury may be the end result of the inflammatory process rather than the major cause of ... are toxic themselves Of interest, in the first identification of SOD, one of the tests of the activity of the enzyme was the prevention of oxidation of catecholamines [33] The potential clinical ... copper/zinc (Cu/Zn) isoform present in the cytosol; SOD2, a manganese (Mn) isoform present in mitochondria; and SOD3, a Cu/Zn isoform present in the extracellular space Knockout of SOD2 in mice...
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Báo cáo y học:

Báo cáo y học: " HIV-1 infection induces changes in expression of cellular splicing factors that regulate alternative viral splicing and virus production in macrophages" doc

Báo cáo khoa học

... Post -Infection 35 Figure HIV- 1 infection on splicing factor mRNAexpression in MDM Effect of5 Effect of HIV- 1 infection on splicing factor mRNAexpression in MDM mRNA was extracted from uninfected ... by SR proteins [37,38] Taken together, the results found for cellular splicing factors in macrophages suggest that HIV- 1 infection changes the splicing factor milieu in these cells in such a way ... during culture or following infection (not shown) mRNA expression To determine whether the changes in splicing factor expression in MDM following infection with HIV- 1 were reflected at the message...
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