the fine structure of slow wave sleep oscillations from single neurons to large networks

Báo cáo khoa học: "TENSE TREES AS THE "FINE STRUCTURE" OF DISCOURSE" ppt

Ngày tải lên : 17/03/2014, 08:20

... with the result." The processing of the (indexical) LF of a new utterance always begins with the root node of the current tense tree (structure) in focus The processing of the top-level operator ... utterances themselves) in a way that echoes the hierarchy of temporal and modal operators of the sentences and clauses from which the tokens arose In this respect, they are anal2In general, the context ... or was stored in the subtree rooted at the focus of T after the laststored episode at the focus of T} Subsequent processing would resemble anaphora disambiguation In the course of further interpreting...

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Tài liệu Đề tài " The causal structure of microlocalized rough Einstein metrics " pptx

Ngày tải lên : 16/02/2014, 05:20

... properties of the components of the Riemann curvature tensor Rαβγδ The remaining sections are occupied with the proof of the Asymptotics Theorem We give a detailed description of their content and the ... the form curl π (2) / + E (2) Strategy of the proof of the Asymptotics Theorem In this section we describe the main ideas in the proof of the Asymptotics Theorem (1) Section We start by making ... given a detailed proof of the theorem by relying heavily on a result, which we have called the Asymptotics Theorem, concerning the geometric properties of the causal structure of appropriately microlocalized...

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Tài liệu Báo cáo khoa học: Crystal structure of Klebsiella sp. ASR1 phytase suggests substrate binding to a preformed active site that meets the requirements of a plant rhizosphere enzyme doc

Ngày tải lên : 16/02/2014, 09:20

... occupancy of 0.6–0.8 to account for the likely effect of radiation damage [33] In order to determine the structure of the complex of an inactive PhyK mutant with its substrate phytase, the reﬁned structure ... phytase of Aspergillus fumigatus shows closer similarity to PhyK in the a ⁄ b domain than in the a domain [20] This is also reﬂected in the rigidity of the protein The atomic displacement factors of ... molecules of the asymmetric unit of the wild-type structure Neither the mutation nor the different crystallization conditions evoked structural differences The crystal was grown in the presence of phytate,...

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Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt

Ngày tải lên : 18/02/2014, 06:20

... on the hACMSD crystals using the same beamline, clearly indicated the presence of a Zn metal ion bound to the enzyme Analysis of the diffraction data set allowed us to assign the crystal to the ... and NAD synthesis The structure of hACMSD in complex with DHAP may used for the design of potent and highly selective enzyme inhibitors that may prove to be of potential interest to reduce life-threatening ... involves formation of a tetrahedral intermediate resulting from the nucleophilic attack of the metalbound hydroxyl group onto the substrate, as observed in other members of the amidohydrolase...

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Tài liệu Báo cáo khoa học: "Understanding the Semantic Structure of Noun Phrase Queries" pptx

Ngày tải lên : 20/02/2014, 04:20

... goal of this work is to identify the semantic labels of IMs, i.e., the attribute names they implicitly refer to We use Ac to denote the set of IM semantic labels for the intent class c Other ... we can directly use the output of a syntactic chunker To be precise, if a query segment is determined by the chunker to be a chunk, we use the indicator of the phrase type of the chunk (e.g., NP, ... semantic understanding of noun phrase queries Assuming that the intent class c ∈ C of a query is known, we cast the problem of extracting the semantic structure of the query into a joint segmentation/classiﬁcation...

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Tài liệu Báo cáo khoa học: Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid doc

Ngày tải lên : 20/02/2014, 11:20

... crystallography The fold of the subunit is similar to that of ScPDC [14] and ZmPDC [15] However, the packing of the two dimers in the tetramer is different from that of the PDCs of known structure, ... in all of the tetrameric PDCs of known three-dimensional structure Binding of the cofactors ThDP and Mg2+ The homo-tetrameric IPDC binds four molecules of the cofactors ThDP and Mg2+ The ThDP ... cofactor to the surface of the protein The entrance of the active site cleft is covered by the C-terminal helix and this part of the polypeptide chain must move in order to allow entry of the...

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Tài liệu Báo cáo khoa học: The solution structure of reduced dimeric copper zinc superoxide dismutase doc

Ngày tải lên : 21/02/2014, 03:20

... calculations, was used to back calculate the NOESY cross-peaks from the calculated structure to assess the quality of the structure The ﬁnal family was made up of 30 structures with the lowest target ... was determined from the ratio of the intensity of the daN(i ) 1,i) and dNa(i,i) NOE found on the 15N plane of residue (i) in the 15 N-NOESY-HSQC Ratio values of the residue (i ) 1) larger than are ... applied to each member of the family using the program AMBER 5.0 [46] The setup of the program and the parameters for the metal ions are as previously reported [21] The value of NOE and torsion...

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Tài liệu Báo cáo khoa học: The crystal structure of coenzyme B12-dependent glycerol dehydratase in complex with cobalamin and propane-1,2-diol pptx

Ngày tải lên : 21/02/2014, 03:20

... R-factor=S||Fo| ) |Fc||/S|Fo| Rwork or the working R-factor is calculated on the 90% of the observed reflections used for the refinement b Rfree or the free R-factor is calculated on the 10% of reflections ... performed, and the monitor and the packing values were checked to determine the result from the candidates We concluded that there is an (abc)2 dimer in an asymmetric unit of the cell The ˚ calculated ... close to those in the diol dehydratase-bound cobalamins (2.9–5.1°) [9,10] Figure 4C indicates the comparison of the position of the a-acetamide side chain of pyrrole ring A of the corrin ring in the...

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Tài liệu Báo cáo Y học: Molecular modeling of the dimeric structure of human lipoprotein lipase and functional studies of the carboxyl-terminal domain docx

Ngày tải lên : 21/02/2014, 15:20

... established Of two possible dimeric structures of LPL, the head-tohead and the head -to- tail models, the studies of the chimeric proteins of hepatic lipase and LPL and the tandem repeat approach of LPL ... procolipase The PL cofactor, procolipase, binds to the C-terminal domain of PL and interacts with the surface loop, presumably stabilizing the open form [18,19] LPL requires the cofactor apoC-II ... in the same direction with the heparin-binding domain at the N-terminal end [14] The other is a cluster of tryptophans (Trp390, Trp393, and Trp394) exposed to the surface (Fig 1A) The cluster of...

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Publicly Funded Agricultural Research and the Changing Structure of U.S. Agriculture doc

Ngày tải lên : 06/03/2014, 15:20

... secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute acts under the responsibility given to the ... members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine The members of the committee responsible for the report were ... of further analysis The Structure of Agriculture The structure of agriculture” is a broad phenomenon involving both the characteristics of farms (the system of agricultural production) and the...

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Báo cáo khoa học: The crystal structure of NlpI A prokaryotic tetratricopeptide repeat protein with a globular fold potx

Ngày tải lên : 07/03/2014, 16:20

... matches to the consensus the full-length HOP, they act to facilitate the assembly of multichaperone regulatory complexes The structural independence of these TPR domains, and the presence of independent ... character to the region The pitch of the overall right-handed superhelix is therefore reduced, which brings the C-terminus up toward the N-terminus Helices and correspond to the region of sequence ... arrays of helices [9,10,13–21] Second, the majority of these (11 structures) are for isolated domains, taken from larger parent proteins Third, of those structures that consist of more than the...

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Báo cáo khoa học: "Understanding the thematic structure of the Qur’an: an exploratory multivariate approach" pdf

Ngày tải lên : 08/03/2014, 04:22

... comparing the profiles The general procedure for thematic interpretation of the cluster tree, therefore, is to work through the levels of the tree from the top, constructing and comparing thematic profiles ... another than to any other profile in the data set The profiles of G can be summarized by a vector s whose dimensionality is that of the data, and each of whose elements contains the mean of the frequencies ... clusters the rows of the data matrix in terms of their relative distance from one another in the data space, it follows that the lexical frequency profiles in a given cluster G are closer to one another...

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Báo cáo khoa học: Molecular mass of macromolecules and subunits and the quaternary structure of hemoglobin from the microcrustacean Daphnia magna ppt

Ngày tải lên : 16/03/2014, 13:20

... [2,4,8,11,12,42] offers the chance to relate the structure and function of this interesting molecule The present study has contributed to this approach: (a) the determination of the molecular mass of the ... further studies on the structure of D magna HB Three-dimensional reconstruction from transmission electron microscopy promises to be a satisfactory way to describe the quaternary structure of ... Accordingly, the present data on the molecular mass of the native Hb complex as well as the Hb subunits are inconsistent In addition, there are only two hypothetical models concerning the structure of the...

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The Economic Structure of Intellectual Property Law pot

Ngày tải lên : 16/03/2014, 15:20

... it, to enable the owners to control the prices of the property they own Neither the withholding, nor the disposal of the property of any one owner will in general affect appreciably the price of ... that as the years go by the relative values of these uses reverse If the recreational users are numerous, the transaction costs of their buying the right to use the river from the factory may ... another makes clear that The Economic Theory of Property 31 31 he is claiming the land and the owner does nothing to contest the claim for years, the law shifts the ownership of the land to the...

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Báo cáo khoa học: Methods to monitor the quaternary structure of G protein-coupled receptors doc

Ngày tải lên : 16/03/2014, 22:20

... assessing the effect of ligand-binding on the quaternary structure of the receptors, the possibility that the antibodies could inhibit binding to the receptor also needs to be controlled Finally, the ... expressed as the ratio of the distance ‘r’ separating the donor and the acceptor over the distance resulting in 50% of the maximal efﬁcacy (R0) As indicated by the Forster equation, the efﬁciency of ¨ ... studies relates to the obligatory use of antibodies Appropriate controls need to be performed to make sure that oligomerization of the partners is not promoted by the bivalent nature of the antibodies...

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Báo cáo khoa học: "Parsing the Internal Structure of Words: A New Paradigm for Chinese Word Segmentation" doc

Ngày tải lên : 17/03/2014, 00:20

... very complex structures By (3)–(5), the generation of word structures is exactly the same as that of ordinary phrase structures Hence the probabilities of these words can be defined in the same way ... denote the set of lexicalized phrase structures in T by C, the set of lexicalized word structures by W, and the set of unknown flat words by F, then the joint probability Pr(T, S) according to our ... S(s) where R is the root part -of- speech headed by the word r, and S is the suffix part -of- speech headed by s If the head of this word is its suffix, then we can define the probability of w by Pr(w)...

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Báo cáo khoa học: The crystal structure of annexin Gh1 from Gossypium hirsutum reveals an unusual S3 cluster Implications for cellulose synthase complex formation and oxidative stress response potx

Ngày tải lên : 17/03/2014, 03:20

... are either distorted or the access of a cation to the site is blocked by the presence of a side chain of a basic residue In case of the IIAB site (Fig 2), the acidic residue acting as the bidentate ... bonding of both sulfhydryl groups to the methionine certainly shifts the thiol-thiolate equilibrium to the deprotonated side and therefore increases the redox potential of the Cys2 system to more ... since the modules are packed much tighter A comparison of the current structure of Anx(Gh1) with the structures of Anx24(Ca32) and AnxA5 reveals that the cotton annexin, in contrast to the bell...

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Báo cáo Y học: The solution structure of gomesin, an antimicrobial cysteine-rich peptide from the spider pptx

Ngày tải lên : 17/03/2014, 23:20

... on each side of the sheet reduces considerably the hydrophobicity of the surface of androctonin when compared to the two other peptides (Fig 5) Mode of action The mode of action of the three peptides ... of the backbones of the 20 final structures The structures are best fitted on the N-Ca-C¢ atoms of the well-defined b sheet (B) schematic representation of the overall fold with the b strands represented ... bilayer, and then to (b) an active state, when the peptide penetrates the hydrocarbon core of the bilayer leading to the disruption of the membrane integrity, probably through the formation of pores...

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Báo cáo khoa học: "TEMPORAL REASONING IN NATURAL LANGUAGE UNDERSTANDING: THE TEMPORAL STRUCTURE OF THE NARRATIVE" docx

Ngày tải lên : 18/03/2014, 02:20

... by their mother to fix the tail v-~hveof the windmilL b In the great expanse of the prairie where they lived, the high tower of the windmill was the only real landmark (Worline, 1956:1) Given the ... dynamics, the stability of their parameters and the resources they consume (Part of the internal dynamics, in the presence of a conscious agent, is the degree of volitional controL) We can then note the ... move into a new FS, accompanied by a promise to return: to return to the immediately preceding FS in the case of interruptions, and to a specified position in the e/s structure in the case of digressions...

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Báo cáo khoa học: The crystal structure of a xyloglucan-speciﬁc endo-b-1,4glucanase from Geotrichum sp. M128 xyloglucanase reveals a key amino acid residue for substrate speciﬁcity potx

Ngày tải lên : 23/03/2014, 05:22

... corresponding to the exo-loop of OXG-RCBH The coordinates and structure factors have been deposited in the Protein Data Bank (PDB) (accession code 3A0F) The structure of XEG was compared with those of other ... that the endoactivity of XEG is primarily attributable to the active site cleft being open at both ends In the case of Xgh74A, the active cleft is open Although a precise analysis of the mode of ... loop because of deletion of those residues The loop structure is responsible for the exo-activity of OXG-RCBH, and the absence of the loop is associated with endo-activity in XEG Therefore, it...

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