... different stages of life and in this way to explore the impact of CF inthe course of a lifetime In comparison to other studies investigating HRQoL inchildrenwith CF, the number of patients in this ... centres participating inthe Benchmarking Project, which has been described in detail by Stern et al [2] The number ofchildrenof this age who participated inthe Benchmarking Project in 2005 was ... show high reliability in at least one ofthe two investigated coefficients which justifies maintaining the structure Construct Validity The majority of item loadings support the model for both German...
... further explore predictors of HRQoL ofchildrenwith asthma This study is, to our knowledge, the first study that investigated predictors of HRQoL inchildrenwith asthma within the context of ... contributed to the explanation of differences found in psychosocial functioning However, interrelations between the different factors inthe prediction of HRQoL remained unclear The aim of our study ... context of other predictors With this study a first step is made in investigating predictors of HRQoL while taking other predictors in account Since most studies investigate only direct relations...
... of swallow initiation In this manner, the time code on the analog video corresponded to the time index ofthe digital recording ofthe vibration signal Methods Representation of swallowing activity ... frequently in rehabilitation engineering, for example, inthe control of neural prostheses [49] and inthe design of an intelligent wheelchair guidance system [50] For our experiments, the number of inputs ... Improving the accuracy of classifiers for the prediction of translation initiation sites in genomic sequences In Advances in Informatics, of Lecture Notes in Computer Science Volume 3746 Springer-Verlag;...
... subscales ofthe original theoretical dimension loaded on the same factor, reducing the number of factors to In mainland China, parents generally believe that the fear of injection, surgery or other invasive ... factor structure inthe original PedSQL version [41] In their study, Emotional Functioning items in both child self- and parent reports not split into two different factors But the findings of ... institution was involved inthe analysis of interpretation of data, in writing the article, or inthe decision to submit the paper for publication The authors are indebted to all participating practitioners...
... removal oftheofthe Bronchoscopic picturetumour carina prior to bronchoscopic Bronchoscopic picture ofthe carina prior to bronchoscopic partial removal ofthe tumour The mucoepidermoid carcinoma ... Unfortunately, the bronchiectasis was not restricted to the RUL; the delay in diagnosis allowed growth ofthe tumour that was so large it obstructed the entire right main bronchus and lead to obstructive ... associated with an underlying respiratory problem and hence requires further workup and follow-up to define the aetiology Also, in children, the recommended minimum investigations for any child with...
... TB inchildren Careful history (including history of TB contact and symptoms consistent with TB) Contact: A close contact is defined as living inthe same household or in frequent contact with ... of TB inchildren HIV testing In areas with a high prevalence of HIV infection inthe general population where TB and HIV infection are likely to co-exist, HIV counselling and testing is indicated ... NTPs Reducing the burden of TB inchildren will require changing and improving many existing practices, such as those that relate to contact investigations These guidelines are based on the best...
... effect Counselling and coping ofchildren and their parents with regard to the possible effects of corticosteroids is therefore essential to help them improve quality of life The reduction of ... effect of maintenance chemotherapy on QoL in childhood ALL in general, and of dexamethasone in particular, should therefore be subject of further studies without jeopardising the cure-rate Page of ... now reaching about 80% With increased survival rates, issues concerning the Quality of Life (QoL) of these children become increasingly relevant This is reflected inthe steady rise in studies...
... coordination Table 1: List of movement Stroop words (Dutch original in parentheses) walking jumping climbing waving kicking bending lifting clambering skating playing football jogging leaning skiing ... demanding task, walkers reduce the complexity of maintaining their gait pattern, resulting in a reduction of gait variability This is in line with previous studies suggesting that individuals with ... highly active in maintaining the abnormal gait pattern In order to cope withthe increased complexity ofthe dual task walkers with LBP even further reduce the flexibility and adaptability of their...
... conducted with pediatric cancer patients during the acute phase ofthe disease, i.e., during ongoing oncological treatment Taken together, these studies suggest that HRQOL inchildren during therapy ... assess the scale structure ofthe remaining items The results supported an internal and external validity ofthe short form that is comparable to the original TACQOL Cronbach's alphas ofthe subscales ... assess the subjective perspective ofthe individual child [5,10,12] The aim ofthe present study was a comprehensive standardized evaluation of self-reported HRQOL inchildren and adolescents during...
... represents the 16% ofchildreninthe Dutch norm population ofthe KIDSCREEN-52 with impaired HRQoL * 95% Confidence interval ofthe proportion ofchildrenwith SCD or healthy siblings with impaired ... and the subjective HRQoL ofchildrenwith SCD While interpreting the results of this study, strengths and limitations should be taken into account Findings of this study are strengthened by the ... reported in Figure The proportion ofchildrenwith SCD with impaired HRQoL (≥1 SD below the mean) was similar to the proportion of healthy siblings with impaired HRQoL However, the proportion of children...
... effect Counselling and coping ofchildren and their parents with regard to the possible effects of corticosteroids is therefore essential to help them improve quality of life The reduction of ... effect of maintenance chemotherapy on QoL in childhood ALL in general, and of dexamethasone in particular, should therefore be subject of further studies without jeopardising the cure-rate Page of ... now reaching about 80% With increased survival rates, issues concerning the Quality of Life (QoL) of these children become increasingly relevant This is reflected inthe steady rise in studies...
... depression The study tended to focus on the side effect profile of clozapine in schizophrenia Dassa D, Kaladjian A, Azorin JM, Giudicelli S.[8] 1993 Clozapine inthe Treatment of Psychotic Refractory ... further pertinent papers The original search initially yielded 147 articles but on further inspection only were thought to be pertinent to the question The lists of references for these papers ... low in her mood However, she experienced hypersalivation and her amitryptiline was increased because of its antimuscarininic effects She was sleeping well with no difficulties getting up in the...
... investigated the sustainable effects of MPH on ADHD behavioral symptoms often simply compared the endpoint withthe baseline ofthe studies [21,22] In our study, we provided the time course of ... weights for the measures of each factor are listed in Table The resultant factors were labeled on the basis of their clinical meaning: CPT distraction (factor 1), CPT impulsivity (factor 2), clinical ... Page of 10 Table The structure of factors produced by principal components analysis of ADHD measuresa,b Factor (CPT distraction) Factor (CPT impulsivity) Factor (Clinical hyperactivity) Factor...
... Ten of 21 studies had no reported infections in either arm, and four further studies had no infections in one ofthe two arms The estimated relative risk of infection associated with GC therapy ... for the arms comparing GC therapy with no-GC exposure If studies were explicit in describing the methods by which they captured infection, nonreporting of infection within the results was assumed ... benefits within the confidence intervals GC therapy might be associated with a ≤ 35% increased risk of infection, or a 30% reduction Although GCs are widely thought to increase the risk of infection,...
... a point that has been defined by other investigators as 'early' Nonetheless, the findings of our study provide the basis for re-examining whether the timing of tracheostomy may impact clinical ... duration of weaning and on the total duration of MV Variables were included inthe final models if they were associated withthe duration of weaning or MV (adjusted P value ≤ 0.05), or if they affected ... median of days (IQR, 2–14 days) after initially meeting readiness criteria Fatigue during weaning was strongly associated withthe duration of weaning and overshadowed the effects of ET when included...
... King J, Soldin SJ: IMMULITE 2000 age and sex-specific reference intervals for alpha fetoprotein, homocysteine, insulin, insulin-like growth factor-1, insulin-like growth factor binding protein-3, ... implemented, however, in large studies with critically ill childrenInthe present study, therefore, insulin sensitivity was indirectly assessed by investigating the insulin response to glucose ... insulin levels in half ofthechildren HOMA showed that insulin resistance as well as b-cell dysfunction resulting in a hypoinsulinemic response resulted in hyperglycemia Insulin resistance,...
... & conducted in neonates) -5 studies conducted in Italy, in USA, in China & in Egypt -3 studies were conducted in emergency departments, in hospital wards, inthe pediatric ICU, and inthe neonatal ... CRs, still remains a challenge in resource-limited settings The AAP recommends the use of CRs cautiously: - potential late adverse effects of ionizing radiation - the lack of findings on CR does ... 1.INTRODUCTION: Pneumonia is the leading cause of illness & death ofchildren (# a global annual incidence of 150 156 million cases inchildren
... (16, 17) In older children, the type of pain is often a function ofthe clinical stage ofthe infection In early HIV, most pain occurs as a result of opportunistic conditions and is, therefore, ... measurement tool Pain assessment involves obtaining information about the location, duration and characteristics ofthe pain, as well as the impact of persisting pain on various aspects ofthe child’s ... assess the extent ofthe child’s restriction in physical and social activities, including school-related activities, during the initial evaluation of pain and the implementation ofthe pain management...
... similar function within the brain Tachykinins may have a role in augmenting the immune functions of CNS glial cells resulting inthe progression of damaging inflammation within the CNS [39] Brain mast ... that the extent ofthe elevation of serum neurokinin A was closely linked to the degree ofthe severity of autism However, it is not easy to determine whether the increase in serum neurokinin A ... invasion into living cells and starting apoptosis, a defect inthe synthesis of apolipoprotein B resulting in accumulation of lipids inside the cell, and downregulation ofthe total protein synthesis...
... presented inthe serum catalyzes the hydrolysis ofthe FAGG; forming furyl acryloyl phenylalanine (FAP) The decrease ofthe absorbance inthe unit time at 340 nm is proportional to the activity ofthe ... state Even inclusion ofthe heterozygous ID state known to have intermediate levels of ACE production along withthe DD genotype depicted a high risk of renal failures Therefore, the finding that ... through reducing the production of angiotensin II with ACEI or by blocking the action of angiotensin II at the AT1R receptor level with A II-type receptor blockers (ARBs), is particularly effective...