the dynamics and mechanisms
báo cáo khoa học: "Dynamics and mechanisms of quantum dot nanoparticle cellular uptake" pps
... may facilitate the transport of the QDs through the cell membrane However, further studies are needed to clarify the mechanisms for the differential cellular uptake of the QDs The observed condensation ... h, the large amount of QDs accumulated inside the cell and their persistence in the lysosomes underscore the need for long-term studies of QD toxicity and fate in cells and clearly emphasizes the ... result of the pH change in these endocytic compartments The pH value in early endosomes is 5.96.0 [37] therefore the QD655-COOH particles are negatively charged and expels one another and stay...
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Tài liệu Banks’ exposure to interest rate risk, their earnings from term transformation, and the dynamics of the term structure pptx
... disentangle the contributions of the systematic factor and of the regulation One can expect some correlation between the regulatory variables outi (t) and out2i (t) on the one hand, and the variables ... contribution of the systematic factor and the regulation to the total timely variation of the exposure is 17.24% and, therefore, 82.76% of the variation is due to idiosyncratic effects These effects ... models: the full model (column 2), the model without the regulation variables (column 3) and the model with only the regulation variables (column 4) The R2 of the full model is 17.24%, i.e the combined...
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Tài liệu Bank mergers and the dynamics of deposit interest rates doc
... +1 ], (12) 0, otherwise, and where x is the value of the explanatory variable (the time distance to the merger, in our case) The values xi denote the “knots” of the spline, and the coefficients, ... opposite, the “structureconduct-performance hypothesis” The “efficiency hypothesis” states that the merged bank might reach economies of scale and other efficiency gains and transfer these to the customers ... concentration and study the dynamics of deposit rates during the first year after a bank merger They are able to document a negative impact of mergers on deposit rates On the other hand, Focarelli and...
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Tài liệu Báo cáo khoa học: Influence of modulated structural dynamics on the kinetics of a-chymotrypsin catalysis Insights through chemical glycosylation, molecular dynamics and domain motion analysis pptx
... (Tables and 5) for the glycoconjugates to determine the dependence of the individual rate constants on the changes in the enzymes structural dynamics The parameters for both the lactose and dextran ... questions of whether and how the enzymes structural dynamics inuence the kinetics of a-CT catalysis This was done by determining the changes in the global structural dynamics (DGHX) [38] for the various ... k2) and (B) deacylation steps (DG k3) for the Lac-a-CT (s) and Dex-a-CT (n) conjugates were independent of the size of the glycan (Tables and 5, [36]) The analysis revealed that the changes in these...
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Tài liệu Báo cáo khoa học: Models and mechanisms of O-O bond activation by cytochrome P450 A critical assessment of the potential role of multiple active intermediates in oxidative catalysis doc
... by the hydrogen ion concentration and ionic strength of the reaction medium [21,24,25] In view of the strategic importance of the oxyferro intermediate in the process of dioxygen activation, the ... of the measurements, of hydroperoxo-iron component relative to the standard redox situation (Scheme 2) This is likely to cause an increase in both the half-life of the scission process and the ... established Thus, methemoglobin and H2O2 transform thianthrene 5-oxide to both the 5,5 -and 5,10-dioxide metabolites [160] The nding that most, if not all, of the sulfoxide oxygen in the 5,5-dioxide...
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Báo cáo khoa học: Amyloid oligomers: dynamics and toxicity in the cytosol and nucleus ppt
... oligomers and interact with other proteins The improvement of microscopic techniques will promote the understanding of the dynamics and toxicity of misfolded proteins in living cells in the near ... molecules in the confocal volume As diffusion coefficients correlate with the friction between the molecule and the solvent, the molecular mass of the molecules can be calculated by assuming the molecular ... shuttles between the nucleus and the cytosol, whereas polyQ-expanded ataxin-1 is not exported from the nucleus [60] These observations suggest that the ataxin-1 accumulated in the nucleus becomes...
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Báo cáo khoa học: Intermodule cooperativity in the structure and dynamics of consecutive complement control modules in human C1r Structural biology docx
... the invariant parts comprising mainly the b-strands The loops between strands B and C, known as the ‘hypervariable loop‘, D and E, E and F, F and G, and G and H are particularly tolerant of longer ... exactly the reverse of the situation observed for the CCP1single and CCP2single modules and probably reflects the complex interdependence of the modules in terms of internal dynamics and may also ... activity and forms a homodimer in neutral solutions [13] The CCP2 module increases the thermal stability of the serine protease and enhances its C1s-cleaving activity CCP modules are common in the...
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Molecular dynamics simulations of the tensile and melting behaviours of silicon nanowires
... [30], and in the present simulation the load is along the [11 0] orientation and the resolved shear stress on the (111) plane causes the sliding After the formation of the neck, the plastic deformations ... as compared with those in the bulk, and the increasing dominance of the surface would decrease the strength of the structure 3.2 The melting properties of the SiNWs The variation of potential ... configuration The strain was then applied along the axial direction to study the mechanical properties of the SiNWs In order to investigate the relative influences of Fig Top and side views of the optimized...
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THE NUCLEAR AND AERIAL DYNAMICS OF THE TUNGUSKA EVENT potx
... and Dwyer, 1976), one being the stream of air molecules entering the volume while the other is the ablating material from the comet surface Further, it is known that under these conditions, the ... D’A~nssro where p is the air density, p is the stagnation gas cap density, R, is the comet radius, cp is the specific heat of the gas and k, is the thermal conductivity The dimensionless quantity ... cP is the specific heat of the gas at constant pressure, y is the ratio of specific heats, c is the speed of sound, (T is the Stefan-Boltzmann constant, pa is the air density and T,, is the temperature...
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Báo cáo khoa học: Mechanisms of obesity and related pathologies: The macro- and microcirculation of adipose tissue pdf
... systemic lipids to their storage depot in the adipocytes On the other hand, the vasculature also transports factors (adipokines) and nutrients (such as free fatty acids) from these cells in time ... cells and adipocytes that encompass the tissue [4] Changes in local and systemic endothelial permeability or endothelial dysfunction induced by adipokines alter transendothelial transport and exclusion, ... VEGF and the adiposespecific leptin and monobutyrin [25], are co-opted to function in conjunction with autonomous tumorderived factors to meet the circulatory demands of the invading lesion The...
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Environmental Innovation Dynamics in the Pulp and Paper industry potx
... the innovation dynamics induced by environmental policy in the pulp and paper industry There has been a fair amount on technical change in the pulp and paper industry in the recent past and there ... also other instruments have been applied, such as water charges in the Netherlands and the electricity tax in Finland The evidence on the relationship between environmental policy instruments and ... Innovation dynamics in pulp and paper able technologies and through the adoption and further development of emerging technologies Table Available and emerging environmental technologies in the pulp and...
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the classical and quantum dynamics of the multispherical nanostructures, 2004, p.400
... are the basis for the theory of electromagnetic field They have been written by English physicist G Maxwell in 1873, and they were the generalization of the experimental facts available then The ... Classical Dynamics where D = εE, B = µH are the vectors of the electric and magnetic induc¯ ¯ ¯ tion respectively, ε = ε0 ε and µ = µ0 µ are the dielectric and magnetic per¯ mittivities, ε and µ are the ... and currents, i.e ρ = and j = The Lagrangian of the electromagnetic field L then reads L = L(E, B) = B , εε0 E − 2µ0 (1.140) where E and B are the electric and magnetic fields accordingly, ε0 and...
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A review of the chemical and physical mechanisms of the storage stability of fast pyrolysis bio oils
... in the reactor • The time and temperature history of the vapors in the reactor • The time and temperature history of the vapors in the heated transfer lines from the pyrolysis reactor through the ... the standard free energy at 25ºC from the literature (DIPPR 1998) for the reactants and the products in the gas phase for the esterification reactions, the free energy for esterification in the ... from the biooil In half the containers, no attempt was made to remove the air above the bio-oil In the other half, the headspace was purged with nitrogen The tightly closed samples were then...
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Báo cáo lâm nghiệp: "Effect of climatic factors on the dynamics of radial increments of Norway spruce, European beech and sessile oak" potx
... precipitation in August of the previous year and July of the actual year is significant for all stands In other cases precipitation in July of the previous year and June of the actual year as well ... increments and monthly precipitation in December and January For 10% and 45% of trees the correlation of precipitation in September and August of the actual year was also significant The correlation ... increments and average monthly temperatures was negligible The highest correlations were found out in stand No 6, where precipitation in June and July of the actual year and in September of the previous...
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Báo cáo lâm nghiệp: "Human land-use, forest dynamics and tree growth at the treeline in the Western Italian Alps" ppt
... reduced In the studied areas, these conditions were present at both the forestline and the treeline in the first decades of the 20th century, favoring the establishment of larch cohorts These cohorts ... (Fig 3) Since the decade of the 1960s there has been a new reduction of grazing intensity and in most of the trees established in the first decades of the 20th century the apex exceeded the browsing ... place in the first decades of the 20th century and a second one after the second world war The highest numbers of inhabitants (3460) were in the middle of the 19th century Afterwards, the number...
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Báo cáo lâm nghiệp: "Picea glauca dynamics and spatial pattern of seedlings regeneration along a chronosequence in the mixedwood section of the boreal forest" potx
... stand dynamics in forest management and restoration in the boreal forest [19] To mimic natural stand dynamics, it is essential to understand the ecology and dynamics of boreal species While there ... proportional to the circle circumference that lies within the plot); It(i,j) is a counter and is equal to when the distance between i and j is less than t and otherwise; and n is the number of ... 93, 157, 172 and 201 y stands in the mixedwood section of Saskatchewan boreal forest The solid line shows the L(t) values, while the dotted line shows the confidence envelope and the average of...
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DESIGN OF MACHINERYAN INTRODUCTION TO THE SYNTHESIS AND ANALYSIS OF MECHANISMS AND MACHINES phần 2 potx
... measure the angle.) The transmission angle 11is shown in Figure 3-3a and is defined as the angle between the output link and the coupler * It is usually taken as the absolute value of the acute ... which the ground plane of the package is accessible It would be preferable if we could define the fixed pivot locations, as well as the three positions of the moving link, and then synthesize the ... Model * and further refine the design, based on the complete analysis of positions, velocities, and accelerations provided by the program The only data needed for the FOURBARprogram are the four...
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DESIGN OF MACHINERYAN INTRODUCTION TO THE SYNTHESIS AND ANALYSIS OF MECHANISMS AND MACHINES phần 3 pot
... for the coordinates of vectors W, Z, D, and S, which define not only the lengths of those links but also the locations of the fixed pivots Oz and 04 in the plane and the lengths oflinks and Link ... vectors Zl and Zz The angle corresponds to the Equations 5.31 can be solved using the approach of equations 5.27 and 5.18, by changing W to U and Z to S and using the definitions of the constants ... equation 5.31 in the matrix to get the coordinates of vectors U and S Equations 5.2 are then solved to find links and 3, and the appropriate vector components are added together to get the locations...
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DESIGN OF MACHINERYAN INTRODUCTION TO THE SYNTHESIS AND ANALYSIS OF MECHANISMS AND MACHINES phần 4 pptx
... your tire rolls against the road without slipping, the road becomes a fixed centrode and the circumference of the tire is the moving centrode The tire is, in effect, the coupler of a linkless ... for 004, the angular velocity of link 4, and also for the velocity of slip at the joint labeled A In Figure 6-18 the axis of slip is shown to be tangent to the slider motion and is the line along ... point A in the same system and the acceleration difference (or relative acceleration) of point P versus pointA These terms are then further broken down into their normal (centripetal) and tangential...
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DESIGN OF MACHINERYAN INTRODUCTION TO THE SYNTHESIS AND ANALYSIS OF MECHANISMS AND MACHINES phần 5 pps
... angle on the fall than on the rise because the stored energy in the spring is attempting to speed up the camshaft on the fall, whereas the cam is storing that energy in the spring on the rise The ... velocity and acceleration, and smoothness of jerk There are many other trade-offs still to be discussed in later sections of this chapter, involving the sizing and the manufacturability of the cam ... the pressure angle and the radius of curvature Both of these involve either the base circle radius on the cam (Rb) when using flat-faced followers, or the prime circle radius on the cam (Rp) when...
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