... denote each of these maps shouldcause no confusion. Annals of Mathematics The homotopy type of the matroid grassmannian By Daniel K. Biss THE HOMOTOPY TYPEOFTHE MATROID GRASSMANNIAN ... systematicstudy of CD manifolds; indeed, the first step in the standard approach to the study of any category in topology or geometry is an analysis ofthe homotopy type ofthe classifying space ofthe accompanying ... playing the linear structure ofthe simplices and the smooth structure ofthe manifoldoff of one another. For a somewhat more precise discussion of this relationship,see Section 3. The world of CD...
... wake at 6 a.m., but nap for two hours or so in the early afternoon. Thus the influence on one's sleep pattern is worthy of consideration when choosing an occupation. ...
... men maintain approximately the same number of hours of unpaid work as in childless households, but the number of hours women work in the home rises to 52 per week, much of it, on doubt, due to ... responsibilities. Interestingly, when there are three or more children in the household, men are found to work even fewer hours around the house than before the appearance ofthe third child. Whereas women's ... The diagram below shows the average hours of unpaid work per week done by people in different categories. (Unpaid work refers to such activities as childcare in the home, housework...
... To the crazy ones. Here’s to thethe misfits. The rebels. The troublemakers. Here’s to the ones who see the world differently. They’re the ones who invent and imagine and create. They’re the ... the historical impact ofthe “Think different ad campaign and the “To the crazy ones” commercial that launched it. There have been a lot ofdifferent accounts of how the work was created, who ... The troublemakers. The people who see the world differently.” And the closing: The people who are crazy enough to believe they can change the world are the ones who actually do.” I felt the...
... reviews[1,2,10].S1 The following segments border the S1-specificity pocket of DESC1: Asp189–Gln192 (the basement of the pocket), Ser214–Gly219 (the entrance frame), Lys224–Tyr228 (the back ofthe pocket) and the ... planes of the bonds between Trp215–Gly216 and Cys191–Gln192sandwich the phenyl ring of benzamidine. The DESC1 S1 pocket resembles the thrombin S1 pocket type because ofthe presence of an Ala rather ... below). The southern boundary of the active site cleft of DESC1 is formed by the 145autolysis loop. The backbone of this loop differs mark-edly from the other serine proteinases, making the act-ive...
... werealso found. The 1H-NMR spectrum revealed the absence of anomericsignals from GlcN I and GlcN II of Lipid A, the lack of pyruvate methyl groups, as a consequence ofthe cleavage of the ketal group ... Elucidation ofthe structure of the lipopolysaccharide core and the linkage between the core and the O-antigen in Pseudomonas aeruginosa immunotype 5 using strongalkaline degradation ofthe lipopolysaccharide. ... found either inwild -type strains and in mutant strains harboring mutationsin the genes encoding enzymes ofthe biosynthesis and/or the transfer ofthe O-specific polysaccharide [12,13]. The core...
... and the backbone amide hydrogen of Ala743 ofthe enzyme, between the side chain carbonyl group of Asn7 of Tat(1–9) and the side chain of Lys554 of DP IV and finally, between the carbonyl group of ... the carbonyl group of Ile8 ofthe peptide interacting with the Tyr752 hydroxyl group ofthe enzyme. A hydrophobicinteractionofthesidechainofMet1ofTat(1–9)withthephenyl ring ofthe substrate Ala-Pro-pNA ... decreased.On the other hand, in the case of Ile3-Tat(1–9) the formation ofthe IEI complex was favored in comparisonto the formation ofthe EI complex. Moreover, for thispeptide binding to the competitive...
... to quantify the amount of recoveredprotein owing to the presence of a high molar excess of BSA remaining in the buffer. Therefore, a fixed aliquot of the protein was incubated with the indicated ... con-firmed the nature of this protein (data not shown).Moreover, the spectrum reported in the figure showed the occurrence of a series of signals that were not interpretedsimply on the basis ofthe ... hypo-thesize a minor involvement of nucleolin in the mechanism of cytotoxicity elicited by the GT oligomers [12]. It seemedprobable that the reactivity ofthe nucleolin was relatedmuch more to the...
... ofthe water from this bulb decreases the temperature ofthe mercury in the tube b in proportion to the dryness ofthe atmosphere, and the number of degrees the tube b indicates below that ofthe ... the ferro-citrate ofthe protoxide, or the peroxide of mercury, or ofthe protoxide of lead, by using creams of thesesalts, or by successive applications ofthe nitrates ofthe respective oxides, ... ruddy snuff-brown, the change of tint coming on rather suddenly about the end ofthe blue or beginning ofthe violet rays of the luminous spectrum. Beyond the extreme violet rays, the action rapidly...
... than the true value, underlining the impact of quite asmall level of contamination on these results.Reassessment ofthe effects ofthe mutations oncoenzyme specificityIn view ofthe dramatically ... few seconds. The small differences in the height of this plateau for different concentrations of enzyme (5–20 lm) are due to shifts in the baselineas a result ofthe contribution ofthe enzyme ... moiety ofthe coenzyme resultingfrom splitting off the nicotinamide ring, suggestingthat the covalent bond between the nicotinamide and the ribose ofthe coenzyme is particularly labile. The signal...
... rates of transcription initiation and elongationbetween the two genes, and ⁄ or from variation in the rates of degradation ofthe two messages. To test the first hypothesis, the gene copy number of ... muta-genesis ofthe c-tubulins of Tetrahymena thermophila[25] and Aspergillus nidulans [26]. Substitution of ala-nine at sites in the lateral surfaces (the H3 helix and the M loop) of these c-tubulins ... structures ofthe a- andb-tubulin [29–31] and ofthe proteins that form the ribo-somal stalk [32]. In the present study, we characterized the two c-tubulin isotypes, c-T1 and c-T2, of E. focardii...
... tyrosine-phosphorylation ofthe insulin receptor or of IRS1, or of phosphorylation of ERK1 ⁄ 2, was not significantly different in either group of diabetics compared with the nondiabetic controls (Table 2). The dose–response ... been the subject of intensive research for many years. Yet, wedon’t know the details ofthe molecular dysregulationin the target cells ofthe hormone. Studies of cells frompatients with the ... that the analyses of insulin effectson glucose transport and thedifferent signal mediators of the hormone were performed on the same cell sam-ple from the same individual. Responses for the...