the development of a novel oral cytologic grading system
Báo cáo y học: "Evaluating the potential of a novel oral lesion exudate collection method coupled with mass spectrometry-based proteomics for oral cancer biomarker discovery" docx
... collect the PerioPaper saliva samples we placed the PerioPaper strip at a location in a healthy volunteer’s oral cavity where ambient saliva had pooled (the back of the lower lip) The strip was allowed ... Ghanny S, DattaGupta S, Thakar A, Chauhan SS, Siu KWM: iTRAQMultidimensional Liquid Chromatography and Tandem Mass Spectrometry-Based Identification of Potential Biomarkers of Oral Epithelial ... ambient saliva, then placed a PerioPaper strip on the location of interest (Oral Pre-Malignant lesion or normal oral epithelium) and allowed it to absorb exudate The PerioPaper was next placed in...
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Application of PEEC modeling for the development of a novel multi gigahertz test interface with fine pitch wafer level package
... resistors and 12 capacitors The ground planes are replaced by the image elements The partial inductance, partial potential coefficient (reciprocal of capacitance) and resistance values are obtained ... typical of the PEEC topology The nodes are separated by the partial inductance L p11 and partial resistance R The excitation and the load currents are I S respectively The partial coefficients of ... equivalent to the actual system matrix The rate of change of energy and hence the perturbation of the system states is proportional to the frequency and the size of the memory elements Thus the...
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Báo cáo khoa học: Identification of preferred substrate sequences for transglutaminase 1 – development of a novel peptide that can efficiently detect cross-linking enzyme activity in the skin pot
... – 2A – 1A QN + 1A + 2A + 3A + 4A + 5A + 6A + 7A + 8A + 9A Fig Assessment of the contribution of each amino acid residue of K5 to substrate recognition Alanine substitution mutants of K5 were produced as ... control The reaction mixture was incubated at 37 °C and then separated by 12.5% SDS–PAGE A fluorograph of the gel was obtained by UV irradiation (254 nm) to visualize the amount of incorporated Dansyl-Cd ... Yoshimura (Graduate School of Bioagricultural Sciences, Nagoya University, Japan) for technical advice on analysis of the tissue sections, and Dr H Shibata of our laboratory for his valuable suggestions...
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Development of a novel toll like receptor based two hybrid assay for detecting protein protein interactions and its application in the study of CD14 dimerization and FcyRIIA activation
... via all the TLRs TIRAP/Mal is a second TIR domain-containing adaptor that specifically mediates the MyD88-dependent pathway via TLR2 and TLR4 In the TLR4 and TLR3mediated signaling pathways, a ... (Medzhitov et al., 1997) TAK1 also activates the p38, JNK and p42/p44 MAPK signaling pathways p38 in turn activates the transcription factor activation protein (AP-1) (Johnson and Lapadat, 2002) A second ... MyD88-independent pathway exists that leads to activation of IRF-3 via TBK1 and IKKε/IKKi The TIR domain-containing adaptor TRIF mediates this MyD88-independent pathway Adopted from Takeda and Akira et al.,...
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Báo cáo khoa học: The antagonistic effect of hydroxyl radical on the development of a hypersensitive response in tobacco pot
... pretreatment; H + ParA1, ParA1 infiltration after H2O treatment; A4 00, 400 lM ABA pretreatment; A + ParA1, ParA1 infiltration after ABA treatment All the spectra were representative of at least three ... suppressed as compared with that in the ParA1 zone In the ParA1 zone, the ion leakage increased dramatically within 12–24 h, whereas in the PR zone the ion leakage rose to a peak of 25% at 12 h and then ... sites at the 5¢ and 3¢ ends, respectively, was obtained by PCR with the following oligonucleotide primers: 5¢-TGAATTCAATAATGTCTAACTTCCGCGCTCTGTTC-3¢ and 5¢-AGGTACCTCAATGATGATGATGAT GATGATGCAGTGACGCGCACGTAGA-3¢...
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Báo cáo khoa học: "Current Research in the Development of a Spoken Language Understanding System using PARSEC*" ppt
... feedback about impossible word candidates • We have been able to incorporate the durational information from Bear and Price quite easily into our framework An advantage of our approach is that the ... incremented by this amount In contrast, Bear and Price, by doubling the size of the grammar are multiplying the processing time by a factor of when no prosodic information is available (assuming (2n) ... Harper Parsec: An architecture for parallel parsing of constraint dependency grammars In Submitted to The Proceedings o /the ~9th Annual Meeting o.f ACL, June 1991 [3] H Maruyama Constraint dependency...
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báo cáo hóa học: " Cognitive interviewing methodology in the development of a pediatric item bank: a patient reported outcomes measurement information system (PROMIS) study" docx
... respond to items and talk about all aspects of their health and well-being in meaningful ways They are able to comprehend varying response options on a categorical scale, and can accurately respond ... using a 7-day recall period Feedback from the children who participated was valuable in creating a set of items to be administered to a wide age range of children The final item set generated as a ... for an interview date At the time of the interview, a trained research assistant obtained parental informed consent and the children signed an assent document All child participants received a...
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Báo cáo khoa học: "Development of a novel antigen capture-ELISA using IgY against porcine interleukin-6 and its application" potx
... is often a difficult and laborious job [4] IgY has the amount of specific extractable antibody in egg yolk than in rabbit in the same period, besides the advantage of a non-invasive antibody sampling ... distant from the road to the nearest swine building above 100m? Is there a separate change area for staff or visitors? Is quarantine area always used for incoming stock? Are cats or dogs allowed ... a sensitive and specific capture-ELISA for the diagnosis of a farm’s sanitary state Materials and Methods Production of recombinant pig IL-6 Cloning of cDNA encoding mature protein: Total RNA...
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Báo cáo y học: " Study protocol: The development of a pilot study employing a randomised controlled design to investigate the feasibility and effects of a peer support program following discharge from a specialist first-episode " pdf
... PSW and the participant will take place on-site with the case manager and the peer support coordinator present The nature of the intervention will be explained again and both the participant and ... in a treatment questionnaire (see below) and via a telephone call made by the RA to the new treating clinician asking about attendance at appointments and medication adherence These treatment adherence ... Ruggeri M, Dall'Agnola R: The development and use of the Verona Expectations for Care Scale (VECS) and the Verona Service Satisfaction Scale (VSSS) for measuring expectations and satisfaction with...
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Báo cáo y học: " ALGOS: the development of a randomized controlled trial testing a case management algorithm designed to reduce suicide risk among suicide attempters" potx
... salary from an organization that may in any way gain or lose financially from the publication of this manuscript - They doesn’t hold any stocks or shares in an organization that may in any way ... name of suicide attempter, the signature of the physician who included the patient, and the logo of the hospital where the patient was originally treated The cards include the phone numbers of the ... kind of study, the data may be biased by an excessive number of patients included and lost of contact To limit this bias and improve the data quality, the participants remained lost of contact...
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Báo cáo y học: " Study protocol for the development of a European measure of best practice for people with long term mental health problems in institutional care (DEMoBinc)" pptx
... previous work, we have found that small payments of this kind greatly facilitate the work of researchers and preserve the dignity of participants as partners in research Such an approach has received ... mental health problems may impact on their capacity to make informed choices for themselves and to participate actively in their care They are at risk of exploitation and abuse from others, including ... or "floating" support staff who are not based at the unit are excluded Ethical approval aspects of the institution (such as the décor and homeliness) by the interviewer A later stage of the study...
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Báo cáo y học: " The development of a knowledge test of depression and its treatment for patients suffering from non-psychotic depression: a psychometric assessment" ppt
... scientific and ethics board of the University of Calgary granted approval for the study Procedures The design involved the development and the psychometric assessment A table of specification (Table ... occasions to review the items for the following: 1) appropriateness of difficulty and relevancy for patients as examinees, 2) concise, clear language at the appropriate level (Grade 9) and was as ... Knowledge of Biological treatments (antidepressants) Knowledge of the delayed onset of the action of antidepressants Ability to act appropriately to failed response to antidepressants Q17 Q21 Ability...
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Báo cáo y học: " Study protocol: the development of a randomised controlled trial testing a postcard intervention designed to reduce suicide risk among young help-seekers" ppsx
... baseline values of an outcome measure as the covariate It is assumed (conservatively) that the covariate would explain 5% of the variance in the dependent variable Based on previous research at ... substantial Safety and supervision The research assistant received training in the administration of the measures and in the assessment of suicide risk The research assistant will make contact ... would be able to detect a small effect size of 0.21 with a significance level of 0.05 and power of 0.8 The actual sample size (n = 165) has made only a small change to the power calculation - the...
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báo cáo khoa học: " A radiographic analysis of tooth morphology following the use of a novel cyclical force device in orthodontics Chung H Kau" pps
... generated from a pulsed scan and required for image generation Image manipulation was carried out using the manufacturer’s software, Galaxis To increase the accuracy of the assessment, all three ... planes (sagittal, axial, and coronal) were utilized CBCT images were taken at two time frames; once at the start of treatment (T1) and again after six months of treatment (T2) Measurements of all ... uSv, as reported by the manufacturer It has a scan time of 14 s and captures the maxilla-mandibular region in a 210° rotation within a radiation-detector configuration The field of view is a spherical...
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Báo cáo y học: " The development of a rapid SYBR one step real-time RT-PCR for detection of porcine reproductive and respiratory syndrome virus" potx
... and avoids potential cross contamination during sample preparation for post-PCR analysis Real-time RT-PCR assays have been widely utilized for early diagnosis of many other animal viral diseases ... viral RNA of all field samples was extracted by using QIAamp Viral RNA Mini Kit (Qiagen) In brief, after lysis of the specimens, the mixture was applied to a spin column as described by the manufacturer's ... sequence data from the PRRSV N protein gene The partial sequence of the N gene of PRRSV strain ch- 1a was downloaded from GenBank (accession no AY032626) and was aligned (using Clustal W program in the...
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Báo cáo khoa học: " Development of a novel monoclonal antibody with reactivity to a wide range of Venezuelan equine encephalitis virus strains" docx
... be essential if this antibody is to find use as an antiviral in humans and these data suggest that CUF37- 2a may be a suitable candidate The pathogenesis of VEEV disease in mice and humans is believed ... propiolactone-inactivated TC-83 antigen and HRP-conjugated mouse anti-phage M13 (Amersham Pharmacia Biotech, U.K.) as the secondary antibody Absorbance values greater than twice the background ... technology and molecular biology techniques The purpose of this work was to create a novel antibody able to react with a wide range of VEEV strains which would have potential as an antiviral therapy...
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báo cáo khoa học: " Development of a novel data mining tool to find cis-elements in rice gene promoter regions" pdf
... Kawai J, Nakamura M, Hirozane-Kishikawa T, Kanagawa S, Arakawa T, Takahashi-Iida J, Murata M, Ninomiya N, Sasaki D, Fukuda S, Tagami M, Yamagata H, Kurita K, Kamiya K, Yamamoto M, Kikuta A, Bito ... A [TC]G [AT ]A [CT]CT AATATATTT TGTCTC TGACGTGG CCA [ACGT]TG CACCC CC [AT]{6}GG AATAAA [CT]AAA CGTG [TC]G [GC] [GC] [GA]CGCC AGCCGCC CCAAT TATA [AT ]A [TA]AAAG CA [ACGT] [ACGT]TG HSF Helix-turn-helix(HTH) ... corresponding to Aux/IAA genes Motif Transcription Factor Family*1 ([ACGT]GAA [ACGT]){3} TGACAGGT CCAC [AC ]A [ACGT] [AC] [ACGT] [CT] [AC] GG [ACGT]CCCAC GTGG [ACGT]CCC CAACA [ACGT]*CACCTG A [TC]G [AT ]A [CT]CT...
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Báo cáo y học: " Control of allergic rhinitis and asthma test – a formal approach to the development of a measuring tool" ppt
... Luciano Margarida Trindade Rita Câmara Rodrigo Alves Additional file CARAT – Control of Allergic Rhinitis and Asthma Test This is a translation to English of the of the preliminary version of ... meeting of the Formal Consensus Process Ana Arrobas Ana Todo-Bom Ângela Gaspar Aurora Carvalho Carlos Alves Carlos Lopes Fernando Calvário Authors' contributions LNS participated in data collection, ... of control of ARA in adult patients with a previous medical diagnosis of ARA A fundamental phase for the accuracy and usefulness of such a tool is its early development A recent systematic review...
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Báo cáo y học: " Construction of doxycyline-dependent mini-HIV-1 variants for the development of a virotherapy against leukemias" pps
... AAA GGA CCA GCA AAG CTC CTC TGG AAA GGT 3') and WS3 (5'TAG AAT TCA AAC TAG GGT ATT TGA CTA AT) The same PCR was performed on DNA from a vpU-deletion construct [pDR2484, [39]] The PCR fragments ... (vpU startcodon inactivation) and rtTAΔ6B (vpU deletion) As part of the vpU inactivation strategy, the Y2 6A inactivating mutation in the tat gene of HIV-rtTA is replaced by the wt tat gene of the ... left panel) Surprisingly, replication of the minimized rtTAΔ 6A and rtTAΔ6B variants is significantly faster than that of the parental HIV-rtTA virus and even faster than the wild type LAI virus...
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Development of a novel immersed boundary lattice boltzmann method and its applications
... computational domain All the numerical computations are easily performed in the computational domain The most popular boundary conforming method is perhaps the arbitrary Lagrangian-Eulerian (ALE) approach ... second law, this momentum exchange can be used to calculate the restoring force at the boundary Chapter Introduction point 1.2.2.3 Advantages and disadvantages of IBM The major advantage of IBM ... penetrate the solid boundary The streamline penetration means that there is a mass transfer across the solid boundary, which can lead to the momentum exchange and inaccurate calculation of forces...
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