... blockades in the G
1
,Sor
G
2
phases ofthe cell cycle, suggesting that the reduction in
cell number may have been the result of a general and
simultaneous blockade of all three phases ofthe cell ... particular
phase ofthe cell cycle, and was associated with an increase
in the sub-G
1
(apoptotic) portion ofthe cell cycle.
We next investigated the effect of combining CDO with
the chemotherapeutic ... established by comparing the size of the
sub-G
1
population in the combination sample with the
numerical sum ofthe separate sub-G
1
populations seen in
cells treated with the individual agents....
... and then considers the responsibility ofthe board
and why its oversight appears to have failed in a number of cases. Other
aspects ofthecorporategovernance framework that contributed to the ... adequacy of its corporategovernance principles
in these key areas.
*
This report is published on the responsibility ofthe OECD Steering Group on CorporateGovernance which agreed
the report ... levels of risk by
following the letter
rather than the intent of
regulations
In some cases, banks have taken on high levels of risk by following
the letter rather than the intent of regulations...
... investigated the ef fect of RVL on the
microvascular phase ofthe hepatic metastasis process of
B16M cells. First, theeffectsof RVL on the capillary
arrest and early metastatic growth of intrasplenically-
injected ... by SPPS statistical software for Microsoft
Windows, release 6.0 (Professional Statistic, Chicago,
IL). Homogeneity ofthe variance was tested using the
Levene test. I f the variances were homogeneous, ... appears to depend on the remarkable inhibitory
effect of RVL on the proangiogenic effectsof tumor-
activated hepatic myofibroblasts [18].
In summary, this study uncovers multiple therapeutic
intervention...
... evalua
te the effect of stocking
biomass ofthe two sizes of
M. lyrata
on
growth performance and survival to enhance
the production and profit of cultivation. The
other parameters within the culture ... evaluation
The estimation ofthe economic benefit of clam
cultured in the intertidal areas is showed in table
7. The net profit is
calculated based on the output
cost and input cost and price ofthe ... on
describing the impact of stocking biomass on the production of clam.
The triplicate experiment had been conducted in 50m
2
plots randomly placed in the intertidal areas to
evaluate theeffectsof stocking...
... increasing ofthe farm workers self-protective
behaviours and perception of control are discussed, too.
The alteration ofthe erythrocyte cholinesterase activity, and the affection ofthe
process of ... exposed to the action of organophosphorus
pesticides in the Mexican state Sinaloa is the objective ofthe investigations, presented
in Chapter 6.
Chapter 7 addresses the work practices ofthe pesticide ... strengthening the hypothesis that exposure to
pesticides could increase the risk of developing Parkinson’s disease.
The objective of Chapter 17 is to review and to highlight some ofthe recent...
... Observatory of Women's Health ofthe Ministry
of Health and Social Policy of Spain.
WHO is grateful for the contributions ofthe authors ofthe individual chapters as well as
the comments ... al., 2008) .The authors
hypothesized that the differential of SO
2
exposure between areas might explain the
differences observed in theeffects but they also evoked the role of other health ... literature search in the Medline database of
the National Library of Medicine. We selected articles as ofthe end of April 2009; the
more recent articles were privileged. The main keywords used...
... vulnerable, population of patients.
Chemotherapy-induced cognitive decline in
the absence of radiation
The best data on the cognitive effectsof chemotherapy alone
have come from studies of children with ... doses
of chemotherapy is clearly demonstrated by Noble and
colleagues [1], yet these proposed studies do not take into
consideration the possible effectsof high-dose chemotherapy
on either CNS ... various combinations of
chemotherapy and cranial radiation. The excellent
correlation ofthe in vitro and in vivo results of Noble and
colleagues’ study [1] raises the hope that the technique
used...
... Furthermore, use of
rescue therapy (cromolyn and salbutamol) was signifi-
cantly lower in the levocetirizine group. The authors con-
cluded that their findings further support the theory of
"united ... effectiveness of antihis-
tamines in human subjects, together with any differences
in onset and duration of action. The majority of these
studies found levocetirizine to be the most potent of the
antihistamines ... or
otherwise ofthe reported anti-inflammatory effectsof levocetirizine to enhance its effectiveness in
the treatment of allergic disease.
Introduction
The effectsof histamine are exerted through three...
... reduce the levels
of anti-apoptotic Mcl-1. The rather low levels of Bcl-2
in the PC3 cells may explain why the radiation-induced
down-modulation of Bcl-2 was of minor importance for
the response of ... cells. Moreover, we compared theeffects of
ErPC3 to theeffectsofthe PI3K inhibitor LY294002.
LY294002 inhibits the upstream kinase PI3K thereby
preventing the activation of Akt. PC3, LNCaP, and
DU145 ... cells
ataspecifictimepoint,butdoesnotindicatewhether
the therapy effects observed are due to inhibition of pro-
liferation, cell death induction, or both. There fore, in a
next step, we examined whether the anti-neoplastic
effects of ErPC3...
... ofthe study, performed the experiments and carried out the
majority ofthe assays, performed the statistical analysis, participated in the
design and coordination ofthe study, and drafted the ... grant No. 3-2994
from the Chief Scientist Office ofthe Ministry of Health, Israel. This study was
a part ofthe PhD thesis of Miri Brodsky.
Author details
1
C.A.I.R. Institute, The Safdiè AIDS and ... activation at 4 h, the lack of modulation of the
NFkB pathway by AS101 at 1 h, concomitantly with the
inhibition of iNOS at that time point, prompted us to
further explo re the mechanism of iNOS inhibition...
... be analysed at the cessa-
tion ofthe study to evaluate the intervention during each
of the phases while the qualitative items will be used to
direct the intervention throughout the study. For ... assess
participants views ofthe quality and quantity of relevant
information received at the point of discharge. It will be
administered at the end ofthe interview in order that the
RA can remind blind ... staffed by the
PSW supervisor and members ofthe research and clinical
team. All PSWs will be required to ensure that the on-call
supervisor knows ofthe time and location of their visit.
The PSW...
... we assessed the effectiveness of prevention mes-
sages contained in the palm card. Several of these mes-
sages were consistent with other messages emanating
from the SEPs (e.g., use of clean cookers ... the
intervention, were responsible for the conduct of this
study at their respective sites, and reviewed drafts of the
manuscript. RH conceived ofthe study and supervised all
aspects of its implementation. ... with the main study.
With respect to post-injection hygiene, 27.8% of those
exposed to the intervention reported usually using the SSs
to stop the flow of blood (Figure 2), suggesting that the
intervention...