the concept of minimally invasive drug delivery
Báo cáo hóa học: " Combination of Polymer Technology and Carbon Nanotube Array for the Development of an Effective Drug Delivery System at Cellular Leve" pptx
Ngày tải lên :
22/06/2014, 00:20
... 3) where C2 is the protein in the bulk, C10 is the concentration inside the gel, S and V1 are, respectively, the surface and the volume of film, V2 is the volume of the bulk, h is the massive exchange ... 24 h, there is a spread of the number of differentiated cells, being about 85% of the total cells In the second day, the number increased up to 90% and, in the third day, about 96% of the cells ... In Fig 2, the scheme of the CNT array-based system for drug delivery proposed in this study is depicted The main structure is composed by the CNT array, embedded with the thin film of alginate...
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Báo cáo y học: "Use of minimally invasive hemodynamic monitoring to assess dynamic changes in cardiac output at the bedside" potx
Ngày tải lên :
14/08/2014, 07:21
... methodological considerations for the validation of monitoring devices Intensive Care Med 2009, 35:1801-1808 doi:10.1186/cc10024 Cite this article as: Pinsky MR: Use of minimally invasive hemodynamic monitoring ... contour algorithms to COtd The two best performers are model flow and the Hemac These methods’ concordance rates were both 96%, indicating good trending ability, unlike the LiDCO and PiCCO cohorts, ... 2011, 15:406 http://ccforum.com/content/15/2/406 cardiac output’ they discuss at length the problems of response time when using the continuous method [5] Dr Pinsky refers in his letter to a paper...
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Evaluation of advanced paclitaxel drug delivery implants for controlled release post surgical treatment against glioblastoma multiforme in the brain
Ngày tải lên :
05/10/2015, 21:33
... times the Area Under the Curve (AUC) levels An AUC level is the area under the curve of a plot of axis between Concentration of the drug vs the duration of exposure to the drug and is used here ... Benjamin CHAPTER 1: INTRODUCTION One of the main challenges of modern pharmacology has been the delivery of the therapeutic agent to the site of action (where the agent is need) and to reach concentration ... solidification of drug- polymer melt This thesis presents a step-by-step approach in the analysis of the use of foams for controlled release of Paclitaxel as implants within the brain for the post-surgical...
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Báo cáo khoa học: Inhibition of PI3K/Akt partially leads to the inhibition of PrPC-induced drug resistance in gastric cancer cells pdf
Ngày tải lên :
07/03/2014, 03:20
... operating at various steps in the cytotoxic activity of the drug, from a decrease of drug accumulation in the cell to abrogation of apoptosis induced by the chemical substance Often several different ... exhibiting IR; 3, 50–75% of the tumor cells exhibiting IR; 4, > 75% of the tumor cells exhibiting IR The overall score was the multiplication of the two The scores were then classified as negative ... immunoreactivity (IR) The staining was semiquantitatively evaluated by assigning a score for the intensity of the IR and for the proportion of cells positively stained The intensity of IR (intensity...
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DICKIE’S INSTITUTIONAL THEORY AND THE “OPENNESS” OF THE CONCEPT OF ART pptx
Ngày tải lên :
23/03/2014, 13:20
... the product of a decision on our part to extend the concept (Weitz, 1956, 188) According to Weitz, this “openness” of the concept of art is the condition of the possibility of further creativity ... Carroll’s theory of historical narratives, one should take into account, for the reasons given above, Weitz’s sound intuition about the open character of the concept of art But on the other hand, the ... examples (e.g the member of a primitive society with no concept of art who creates the representation of a leopard and manages to endow it with something of the fearsomeness of the animal; see...
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Báo cáo hóa học: " Research Article Coorbit Theory, Multi-α-Modulation Frames, and the Concept of Joint Sparsity for Medical " ppt
Ngày tải lên :
22/06/2014, 01:20
... device with 151 sensors (coils) The color encodes the Gaussian weighting, that is, the influence of the synthetic background signal The center of appearance of the synthetic signal is marked by a ... with respect to a suitable set of building blocks These building blocks may, for example, consist of the elements of a basis, a frame, or even of the elements of huge dictionaries Classical examples ... and the WeylHeisenberg group, one obtains the Besov spaces and the modulation spaces, respectively In the setting of the affine Weyl-Heisenberg group and the specific case vs (ω) = (1 + s |ω|) , the...
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CHAPTER 4: THE CONCEPT OF MEASUREMENT IN THE MARKETING RESEARCH docx
Ngày tải lên :
09/07/2014, 17:20
... CONTENTS The concept of measurement; What is measured?; The benefits of the measurement; The laws (rules) of measurement; Measure scales; Three standards of a measurement; Psychological measure; The ... reactions of skin, blood pressure, heart rate, and pupil of the eyes, the senses of man However, in the interview we usually apply the attitude scales 23 6.1 The normal psychological measure In the ... (+/-), if using division (/), the results will be meanless 16 4.4 The Ratio scale The Ratio scale has all of particularity of the interval scale Moreover, the point in the ratio scale is a value...
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Báo cáo toán học: "How to include organ interactions in models of the root system architecture? The concept of endogenous environment " potx
Ngày tải lên :
08/08/2014, 14:22
... represents the apparent extension of the interaction zone but only to that of their mother root The global response was essentially local, since only the laterals close to the tip of the mother root ... responded In the second example [7], the growing medium of the root system was artificially made heterogeneous by the means of a hydroponics system, in which the major part of the root system bathed ... along the shoot This pattern of emergence is highly organised, since the roots on a given node appear only when the roots of the node just beneath have completed their emergence Furthermore, the...
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Báo cáo y học: "The concept of “compartment allergy": prilocaine injected into different skin layers" pdf
Ngày tải lên :
08/08/2014, 21:20
... and ZG gathered the patient’s history and prepared the clinical pictures AT supervised the interpretation of the data and the design of the allergologic work-up MW organized and finalised the manuscript ... another example for the concept of compartment allergy Consent Written informed consent was obtained from the patient for publication of this case report and any accompanying images A copy of the ... drafting the manuscript and revising it critically for important intellectual content All authors read and approved the final version of the manuscript Competing interests The authors declare that they...
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Báo cáo khoa học: "Clinical review: Reappraising the concept of immediate defibrillatory attempts for out-of-hospital ventricular fibrillation" pptx
Ngày tải lên :
12/08/2014, 20:20
... in the subset of patients presenting with VF In fact, in some of the clinical trials of high-dose adrenaline, on average the first drugs were given as late as 17 following notification of the ... greater than The response interval was measured from the time of dispatch of emergency vehicles until the time of arrival at the street address (not time of collapse to arrival at the patient’s ... greater than The response interval was measured from the time of dispatch of emergency vehicles until the time of arrival at the street address (not time of collapse to arrival at the patient’s...
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Báo cáo y học: "Pro/con debate: Do the benefits of regionalized critical care delivery outweigh the risks of interfacility patient transport" pot
Ngày tải lên :
13/08/2014, 16:20
... to quantify or predict the impact of these phenomena, the effects of regionalization on lowvolume centres should not be underestimated, both in terms of care delivery and the effect on healthcare ... nature of their physiological instability, may clinically deteriorate even if they remain in the ICU, and it is important to compare the incidence of adverse events during transport against the ... demonstrating the benefit of this strategy where regionalization is not already in place There is one recent study that attempted to estimate the impact of regionalizing the provision of mechanical...
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Báo cáo y học: "Reappraising the concept of massive transfusion in trauma" doc
Ngày tải lên :
14/08/2014, 07:21
... and the prothrombin time, which are the main features driving the development of ATC [6] Page of The performance of the tool might be improved if a better near-patient measure of the severity of ... in the emergency department However, the performance of the model was only moderate, and the AUC of our tool of 0.81 is consistent with other prediction tools (0.68 to 0.85) [15-20] Setting the ... outside of their original datasets We designed this international multicenter study to reappraise the utility of massive transfusion as a clinical concept in modern trauma care The first aim of the...
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Design and fabrication of microneedles for drug delivery
Ngày tải lên :
14/09/2015, 11:17
... fracture of the material W1 the neck width for inlet W2 the neck width for outlet Vx, the velocity of the fluid in x direction Vy the velocity of the fluid in y direction Vz the velocity of the fluid ... allow the implementation of time varying delivery of different therapeutics, which is essential for a more effective drug delivery system The direct delivery of DNA/portent based drugs into the ... and, therefore, improve drug delivery efficiency With microholes in the skin, the drug delivery relied mainly on the Chapter Introduction subsequent drug absorption into the bloodstream rather...
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The concept of human nature in wei jin chinese philosophy
Ngày tải lên :
16/09/2015, 08:30
... ruler and the father observe the nature of the minister and the son If their nature is good, the ruler and the father will nurture and guide them, keeping them far away from the bad If their nature ... consistent in the second part of chapter Wang Xiaoyi contributes to the scholarship of the period with his panoramic portrait of Learning of the Profound His clarification of the concept of nature ... Account of Tales of the World, 346 Shishuoxinyu 世說新語, 392; A New Account of Tales of the World, 402 4 The social and intellectual context of Han-Wei The last years of the Han dynasty and the subsequent...
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The concept of irony in jane austen, with constant reference to virginia woolf
Ngày tải lên :
16/10/2015, 12:00
... denial of the affective powers of irony If the critics admit their emotional reaction to irony, then they risk becoming the object of irony: this personal stake in the concept of irony removes the ... protagonist The blending of the protagonist’s voice with the narrator’s, together with evidence in the text that contradicts the views of either or both, ironise and destabilise the views of these ... against didacticism Of R.J Farrer’s book, The House of Shadows, she writes: The drawback of the concentration which is the result of the scheme of the book is naturally that the characters are...
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Mencius and xunzi on moral agency and the concept of neng
Ngày tải lên :
26/11/2015, 10:49
... “tastes” of the heart-mind the natural attraction of the heart-mind to ethical things When the likings of the heart-mind are activated in response to the stimuli of certain circumstances, impulses of ... to get in the good books of its parents, the desire to win the accolades of those at the scene, and the desire to relieve the vicarious distress one feels due to the unpleasantness of the child’s ... by asserting the erroneousness in thinking that the orientation of the heart-mind towards yi can be sought from the influence of qi motility on the workings of the heart-mind In other words, Gaozi...
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An investigation into metaphors related to the concept of Dignity in Oliver Twist by Charles Dickens via its Vietnamese version translated by Phan Ngoc
Ngày tải lên :
02/06/2016, 17:08
... Nhật, PhD The Thesis was defended at the Examination Council for the M.A thesis, the University of Danang Time : December 15th, 2013 Venue : The University of Danang The original of this thesis is ... [48, p 74] The percentage of the phenomenon of loss of meaning is presented as follows: Figure 2: The percentage of loss of meaning 18 4.3.2 Gain of Meaning in lexical feature a Gain of Conceptual ... to the ideas of the author, the teachers should guide them to employ appropriate and approaches On the part of the students, with a good understanding and using of the translation stragegies, they...
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Cognitive linguistic features of idioms related to the concept of black, white in english versus vietnamese
Ngày tải lên :
06/06/2016, 15:00
... identify the literal and figurative meanings of these idioms On the other hand, the learners should equip themselves with the knowledge of cultural background as much as possible They should study the ... Interpreting the denotative meaning of the given idioms related to the concept of “Black”, “White” in the source language + Clarifying the connotative of the idiom mentioned + Explaining the general ... related to the concept of “Black”, “White” and vice versa 10 + Type 4: Vietnamese idiom related to the concept of “Black”, “White” has no English equivalents related to the concept of “Black”,...
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Chap 1 marketing and the concept of planning and strategy
Ngày tải lên :
11/01/2017, 15:31
... define what business the company is in or is to be in and the kind of company it is or is to be CHAPTER 1: Marketing and the Concept of Planning and Strategy 161 1-4 IMPORTANCE OF STRATEGY Any organization ... about control of initiative 162 CHAPTER 1: Marketing and the Concept of Planning and Strategy 1-5 DEFINITION OF STRATEGIC PLAN Strategic plan specifies the sequence and timing of steps that ... set of criteria consisting of price, competitors, customer groups, and shared experience: a Price—To the extent that price changes in a product entail a review of the pricing policy of other...
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THE CHEMISTRY OF DRUG DELIVERY SYSTEMS (hoá học các hệ dẫn truyền thuốc)
Ngày tải lên :
18/04/2014, 15:37
... Frequencies of dosing A1, A2, A3, A4: series of multiple doses of a conventional drug delivery system B: ideal drug concentration profile PRODRUG What is a prodrug? Prodrug is an inactive precursor of ... concentration at the site of drug action Roles: Carry Transport Protect Distribute Enhance body retention, the efficacy of the treatment ROUTES OF DRUG ADMINISTRATION Topical delivery ORAL DELIVERY (GASTROINTESTINAL ... enhancers: SELECTION OF ROUTE OF DRUG ADMINISTRATION Affects the onset and duration of drug action Ex: Administration of nitroglycerin Depends on the desired drug concentration profiles to be achieve,...
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