the complex biology of an emerging pathogen
Tài liệu Characterization of the Polymorphic Behavior of an Organic Compound Using a Dynamic Thermal and X-ray Powder Diffraction Technique pptx
... characterize the polymorphic behavior of an organic compound API over a temperature range of hundreds of degrees This allows the simultaneous measurements of thermochemical and thermophysical ... (see Figures and 9) The lack of any additional peaks in the XRPD patterns would imply the presence of an Figure DSC of atypical anhydrous Form I (sample 11) amorphous material and/or an impurity ... through the center of the sample and reference sensors of the DSC cell Thermal isolation was maintained by using beryllium metal foil to seal the X-ray optical path identification and understanding of...
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Tài liệu Báo cáo khoa học: Understanding the binding properties of an unusual metal-binding protein ) a study of bacterial frataxin pdf
... from the other Disappearance of some resonances without the obvious appearance of new signals suggests the presence of an intermediate rateexchanging equilibrium between the resonances of the ... disappearance of specific resonances without the concomitant appearance of other signals in other parts of the spectrum This result could be a consequence of the paramagnetic properties of Fe(II), ... al be due to the presence of an exchange mechanism between the metal-bound and the free species, due to the low affinities of the complexes involved The residues that undergo resonance shifts must...
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Tài liệu Báo cáo khoa học: Coordination chemistry of iron(III)±porphyrin±antibody complexes In¯uence on the peroxidase activity of the axial coordination of an imidazole on the iron atom ppt
... the antibody and particularly to appreciate the size of the cavity left around the iron atom and which kind of ligands it can accommodate; second, to measure the in¯uence of an axial ligand of ... (Table 1) The binding of the ®rst CN± ligand to the iron was thus more easy in the hydrophobic binding pocket of the antibody than the binding of the second one, most probably because of the steric ... bound to the iron, the steric hindrance due to the substituent could be balanced by a distortion of the porphyrin ring and a shift of the iron atom outside the plane of the porphyrin Binding of imidazole...
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Báo cáo khoa học: The catalytic mechanism of dye-decolorizing peroxidase DyP may require the swinging movement of an aspartic acid residue potx
... H2O2 and CN, the position of the carbon atom of CN bound to the heme iron mimics the position of the proximal oxygen of H2O2 bound to the heme iron during compound I formation Therefore, the carbon ... achieved with the hang- Fig The swinging mechanism of Asp171 (A) Interpretation of distances between Asp171 and a virtual proximal oxygen of H2O2 in the native and D171N-CN The native and D171N-CN ... the heme planes Note that Asn171 of D171N-CN is shown as Asp171 To avoid misunderstanding, only the heme of the native is shown in white The position of the CN carbon mimics the position of the...
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Reflexing Interfaces: The Complex Coevolution of Information Technology Ecosystems doc
... use of the term in psychology (with the meaning of purpose), in medicine (with the meaning of the mode of healing and integration of the body), and in analytic philosophy (with the meaning of the ... This creature possessed the body of a dog, the claws of a lion, the tail of a dragon, the wings of a bird, and the breasts and head of a woman The Sphinx began to ravage Thebes, stopping all mountain ... observation of hand movements in the monkey is present in the common ancestor of monkey and human It is the precursor of the crucial language property of parity, namely that an utterance usually...
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the accidental death of an anarchist
... political amalgamation of lies aimed at hiding the truth behind the anarchist's death There were many themes presented in ADOA including that of the abuse of power by the authoritarian This occurs when ... By breaking down the fourth wall, the audience becomes co-conspirators, and part of the political conspiracy Through the Maniac's exaggerated and comic view of the court system, the responder also ... of the truth i.e the Italian police and the corrupt nature of society This is shown when the Maniac ridicules the police by burning and throwing out documents, mocking the way the police destroy...
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EVOLUTION OF THE MOLECULAR BIOLOGY OF BRAIN TUMORS AND THE THERAPEUTIC IMPLICATIONS pdf
... compounds of the ECM of the brain tissue have many specific differences from other human organs The ECM of the brain contains mainly macromolecules like glycosaminoglycans (GAGs) and proteoglycans ... mortality of the patient Moreover, the presence of the blood-brain barrier (BBB) limits the passage of a wide variety of anticancer agents The high incidence of recur‐ rence and poor prognosis of malignant ... Hofmann M Characterisation of the murine gene encoding the intracellular hyaluronan receptor IHABP (RHAMM) Gene 1999;226:41 23 24 Evolution of the Molecular Biology of Brain Tumors and the Therapeutic...
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Báo cáo khoa học: The role of residues R97 and Y331 in modulating the pH optimum of an insect b-glycosidase of family 1 pdf
... deglycosylation) of the hydrolysis of MUbglc by the mutant enzymes is rate-limiting, no hypothesis on the effect of R97 and Y331 on the rate constant of each step can be advanced ể FEBS 2003 Mechanism of ... As the pKa values of the catalytic residues determine the pH optima, the ionization constants (pKa) of the catalytic glutamates (E187 and E399) in the ES complex and in the free enzyme (E) of ... b-glucosidase affected the rate constant of the glycosylation step and also changed the enzyme pH optimum [14] Despite that, the effect of the tyrosine on the pKa values of the b-glycosidase catalytic...
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hack the stack - using snort & ethereal to master the 8 layers of an insecure network
... to another Port 20 is used for the data stream, and transfers the data between the client and the server Port 21 is the control stream, and is used to pass commands between the client and the ... attacks, the bulk of the work of a social engineering attack is doing the reconnaissance and laying the groundwork .The attack itself usually takes on one of the following angles: ■ Diffusion of Responsibility ... Organization of This Book This book is arranged in the same manner as the layers of the OSI model, which was developed to provide organization and structure to the world of networking In 1983, the...
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Báo cáo khoa học: Understanding the complex mechanisms of b2-microglobulin amyloid assembly potx
... analysed the folding and unfolding kinetics of b2m under an array of conditions, including analysis of the folding mechanism of the variant P32G Using global analysis of the resulting kinetic data, the ... residues in the BC- and FGloops, the D-strand and the N-terminal region of the protein that presumably arise from the isomerization of Pro32 and subsequent partial unfolding of the protein [67] These ... Chiti and colleagues [82], more detailed studies of the folding and unfolding mechanism of wild-type b2m, combined with mutagenesis of the sequence, demonstrated that the transition between the...
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The Complex World of Polysaccharides Edited by Desiree Nedra Karunaratne pptx
... effects of chitosan and many other cationic agents are based on their ability to increase the permeability of the outer membrane of Gram negative microorganisms to an extent incompatible with their ... substances related to pain and the levels of this substance decrease in the presence of chitin and chitosan Chitin absorbs Bradykinin more extensively than chitosan and this could be one of the ... on the properties of the polymer before the application Is Chitosan a New Panacea? Areas of Application 29 Also, through the study of this biopolymer and due to the great demand of chitin and...
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numerical analysis of the spectral response of an nsom measurement
... gives the magnitude of the energy flow and its direction Figure shows the sum of the energy density stored in the electric and magnetic field and the magnitude of the Poynting vector at the center of ... respectively The variance of the permittivity shown in Fig is reflected in both the near and far-fields and the peaks from the PEC model are dra- Numerical analysis of the spectral response of an NSOM ... is that the E field is orthogonal to the H field and scaled by η, the impedance of the medium This allows easy calculation of the radiated power The far-field response has both an angular and spectral...
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the evolutionary biology of human female sexuality sep 2008
... is the foveal blind spot The wiring of the photocells of the vertebrate eye exit the cells on the inner face, not the exterior, of the retina Where they converge and together exit the eye, they ... possess them The causes of both the origin and maintenance of mammary glands jointly explain their existence today But these causes are themselves distinct 18 The Evolutionary Biology of Human Female ... example, their ratings of the pleasantness of the scent of a T-shirt, of the attractiveness of a person’s face (as presented in a photograph), or of the attractiveness of a person’s voice These...
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university of texas press thelma & louise live the cultural afterlife of an american film nov 2007
... take advantage of the sweep of the American West, situating the personal development of the characters into the visual iconography of the American cinema and history In Thelma & Louise: The Last ... image of an empty two-lane blacktop road, emerging from the bottom center of the poster and leading toward an image of Monument Valley, a horizon of mesas and rocks across the lowest quarter of the ... availability, the absence of civilization, and so hides the histories of the West in favor of the familiar fantasies of the West as an unoccupied place of self-creation for Anglo tourists (like their...
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university of texas press the teotihuacan trinity the sociopolitical structure of an ancient mesoamerican city dec 2007
... exploring the nature of these three groups and gaining an understanding of their foundations can we return to the overarching agenda of the state and see possible models for the integration of the ... Teotihuacan and the appearance of the Teotihuacan state outside the Valley of Mexico This suggests that the manufacture and trade of obsidian were at least partially responsible for an increased ... most of the construction at Teotihuacan concentrated on the grand pyramids along the main avenue, but during the end of the Miccaotli and the beginning of the Tlamimilolpa periods (a.d 200–250) an...
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Báo cáo hóa học: " Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood" pptx
... performed all the studies on human samples reported here, analyzed the data and co-wrote the manuscript SJ and AAW performed all the pilot studies in humans and monkeys that identified the candidate ... data analysis and review and participated in the drafting of the manuscript DY co-led the Ab-01 team and was responsible for studies related to the characterization of the biological properties of ... observed in both humans and monkeys The presence of IL21R on the top gene list for monkeys and not for humans reflects a higher relative ranking in monkeys due to the lack of IFNγ and CD19 data in...
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báo cáo sinh học:" Empowering the people: Development of an HIV peer education model for low literacy rural communities in India" pdf
... KK, VC and DS participated in the initial concept, the design of the study and the development of the IEC materials KVR assisted in data analysis and drafted the manuscript MR designed the monitoring ... formed by the OW of READ [10]) performed street theatre with acts that illustrated the modes of HIV transmission, the impact of the disease on the body's defences of the infected person, and ultimately ... to loans for micro-enterprise development) Monitoring and evaluation The evaluation of PEPP involved the collection and analysis of both quantitative and qualitative data Triangulation of data...
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Báo cáo sinh học: " Molecular advances in the cell biology of SARS-CoV and current disease prevention strategies" doc
... fecaloral are therefore possible Brief overview of the SARS-CoV genome The virus has been isolated from wild animals (Himalayan palm civets and raccoon dogs) found in the animal markets of Guangdong, ... this molecule [31] These evolutionary mechanisms may have facilitated the adaptation of the animalborne SARS-CoV ancestor to the human host, suggesting that such events in the future could lead ... "Y"s) on the surface The virus enters the cell, uncoats, and the viral RNA is replicated and translated The SARS-CoV U122 protein induces apoptosis in cells SARS-CoV S and N proteins each can activate...
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báo cáo hóa học:" New quality and quantity indices in science (NewQIS): the study protocol of an international project" docx
... is obvious that the policy for the allocation of research grants could benefit from an increase in 1) objectivity and 2) transparency This is due to the fact that non-transparent and questionable ... Ltd ence, specific organs, diseases or other phenomena 2) countries 3) publication dates 4) authors 5) affiliations depending on the focus of the study The data can then be transferred to visualisation ... asthma, the first being published in the year 1968 [14] These studies were published by 52 countries The US, Japan and the UK were the most productive countries, participating in 55.8% of all...
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báo cáo hóa học:" Difficulty in diagnosing the pathological nature of an acute fracture of the clavicle: a case report" ppt
... conceived the idea and wrote the paper SA and SM analysed the notes and contributed to the discussion CBH was responsible for editing and approving the final manuscript All authors read and approved the ... (CT) scan of the thorax, abdomen and pelvis revealed a right renal tumour with metastases to the lungs, liver and bone The bone metastases were to the left clavicle and the right ilium A further ... investigations, and may include further imaging of the clavicle with cone views and upper rib radiographs or a CT scan to adequately delineate the fracture and the quality of the surrounding...
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Tìm thêm: xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25