the anti inflammatory benefits of a multivitamin supplement
Báo cáo y học: "tatin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis" pptx
... O2 and treated with atorvastatin for the indicated times and then RNA was extracted using the RNeasy kit (Qiagen Ltd, Crawley, UK) Total RNA was separated on a 1% agarose/formaldehyde gel, transferred ... individual experiments ± the standard error of the mean Data were analysed using one-way or two-way analysis of variance with Bonferroni correction Normalized data were analysed using the Wilcoxon Rank ... hypoxia and atorvastatin Northern analysis was performed to determine whether the change in CD59 expression involved gene transcription mRNA was extracted from unstimulated and atorvastatin- Available...
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Báo cáo y học: "The anti-inflammatory effects of levocetirizine - are they clinically relevant or just an interesting additional effect" pptx
... improvements in nasal symptoms and airflow in patients with seasonal allergic rhinitis may be associated with attenuation of inflammatory markers in the nasal passages of these individuals More recently ... investigating the mechanisms underlying the effects of H1-antihistamines have indicated that, in addition to their being a potent antihistamine, levocetirizine exhibits anti- allergic/antiinflammatory ... considerable interest in the effect of anti- inflammatory drugs on the pro -inflammatory processes responsible for the manifestations of allergic disease Antiinflammatory effects independent of H1-receptor...
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Báo cáo y học: "The PI3K–NF-κB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis" pdf
... In the present study we show that IB-MECA, a synthetic A3 AR agonist, acts as an anti- inflammatory agent and ameliorates the development of AIA IB-MECA inhibited the disease clinical score and the ... intrinsic caspase pathway Mol Cell Neurosci 2003, 22:365-382 33 Miyashita T, Kawakami A, Tamai M, Izumi Y, Mingguo H, Tanaka F, Abiru S, Nakashima K, Iwanaga N, Aratake K, et al.: Akt is an endogenous ... amelioration of the inflammatory process Page of (page number not for citation purposes) Materials and methods Reagents The A3 AR agonist IB-MECA was synthesized for Can-Fite BioPharma by Albany...
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Báo cáo y học: "Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A3 adenosine receptor expression" doc
... Haemek (Haifa, Israel) The A3 AR antagonist MRS1523 was purchased from Sigma (St Louis, MO, USA) and diluted in the same manner as for CF101 Rabbit polyclonal antibodies against rat and human A3 AR ... designated the standard The blots were quantified by densitometric analysis and the ratio of RA patient/standard was calculated Blots of mitogen stimulated cells were quantified against β-actin The ... A3 AR as well as rat A2 AAR were purchased from Santa Cruz Biotechnology Inc (Santa Cruz, CA, USA) MTX, PHA, adenosine and adenosine deaminase (ADA) were purchased from ABIC (Beit Shemesh, Israel)...
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báo cáo khoa học: "The anti-myeloma activity of a novel purine scaffold HSP90 inhibitor PU-H71 is via inhibition of both HSP90A and HSP90B1" docx
... implemented the study, and drafted the manuscript RB and GC participated in the implementation of the study, and the acquisition, analysis and interpretation of data All authors have read and approved the ... of a phase dose-escalation study Br J Haematol 150:438-445 Nakashima T, Ishii T, Tagaya H, Seike T, Nakagawa H, Kanda Y, Akinaga S, Soga S, Shiotsu Y: New molecular and biological mechanism of ... mediated by genotoxic drug melphalan and doxorubicin, and to thalidomide that has a yet not fully understood mechanism of action The anti- myeloma activity of PUH71 and the geldanamycin analogues...
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Báo cáo y học: "Anti-inflammatory potential of a malleable matrix composed of fermented whey proteins and lactic acid bacteria in an atopic dermatitis model" pot
... immunomodulatory agent as well as to be an anti- inflammatory agent in the context of inflamma- JB design the animal studies, carried out the animal and other experiments, perform the statistical analysis ... and young adult suffering from chronic inflammatory of various diseases such as ACD The consumption of the MPM could act as a preventive or a therapeutic nutraceutical in the case of inflammatory ... on Animal Care as specified in the Guide to the Care and Use of Experimental Animals (CISAU # 0306-01 and # 0410-01) Mouse atopic contact dermatitis (ACD) After a week adaptation in the animal...
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Báo cáo y học: " The anti-inflammatory effects of the tellurium redox modulating compound, AS101, are associated with regulation of NFB signaling pathway and nitric oxide induction in macrophages" doc
... GH carried out the IL-6 ELISA, participated in the statistical analysis and in the coordination of the study MA participated in the design of the study, its coordination and drafted the manuscript ... down-regulation of IkappaB kinase and NFkappaB activation in macrophages Biochem Pharmacol 2000, 60:1665-76 Kabe Y, Ando K, Hirao S, Yoshida M, Handa H: Redox regulation of NFkappaB activation: ... conceived of the study, participated in the design and coordination of the study, and drafted the manuscript All authors read and approved the final manuscript Page of 20 21 22 Competing interests The...
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Báo cáo y học: " Peripheral muscarinic receptors mediate the anti-inflammatory effects of auricular acupuncture" ppsx
... posterio-medial (area B), posterio-lateral (area C) and anterio-lateral (area D) (Figure 1A) corresponding to the cymba conchae, cavita conchae, helix-scapha-antihelix and triangular fossa-crura anthelicis ... anti- inflammatory effects of AA The cholinergic muscarinic mechanism appears to be more important than the opioid mechanism in the anti- inflammatory action of AA Abbreviations AA: Auricular acupuncture; ... found that the thermal pain threshold was significantly increased after AA and administration of naloxone This was unexpected because neither AA nor naloxone alone altered the thermal pain threshold...
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Báo cáo y học: " ncremental cost effectiveness of proton pump inhibitors for the prevention of non-steroidal anti-inflammatory drug ulcers: a pharmacoeconomic analysis linked to a case-control study" potx
... studies vary, they all used actual primary clinical data from trials and applied them to an economic model These data may however not always be generalised outside the controlled environment of the ... Arthritis Research & Therapy Vol 10 No Vonkeman et al with NSAIDs) with the appropriate pharmacoeconomic information Materials and methods The pharmacoeconomic evaluation was linked to a 26-month ... Chicago, IL, USA) Bootstrap analyses were performed using the software package S-plus (TIBCO Software Inc., Palo Alto, California, USA) professional version 6.0 Cost effectiveness To calculate the...
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Báo cáo y học: "Incremental cost effectiveness of proton pump inhibitors for the prevention of non-steroidal anti-inflammatory drug ulcers: a pharmacoeconomic analysis linked to a case-control study" pptx
... studies vary, they all used actual primary clinical data from trials and applied them to an economic model These data may however not always be generalised outside the controlled environment of the ... Arthritis Research & Therapy Vol 10 No Vonkeman et al with NSAIDs) with the appropriate pharmacoeconomic information Materials and methods The pharmacoeconomic evaluation was linked to a 26-month ... Chicago, IL, USA) Bootstrap analyses were performed using the software package S-plus (TIBCO Software Inc., Palo Alto, California, USA) professional version 6.0 Cost effectiveness To calculate the...
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Báo cáo y học: "Anti-inflammatory effects of antidepressant and atypical antipsychotic medication for the treatment of major depression and comorbid arthritis: a case report" pdf
... Eyre: Anti- inflammatory effects of antidepressant and atypical antipsychotic medication for the treatment of major depression and comorbid arthritis: a case report Journal of Medical Case Reports ... carried out in this area, thus leaving a lack of data on the potential anti- inflammatory effects of escitalopram despite a recent finding that escitalopram lowers the level of soluble interleukin ... Conclusions This case report suggests that in addition to the known anti- inflammatory effects of SSRI, the treatment particularly with quetipiane may have stronger anti- inflammatory (reduction of CRP levels)...
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peer-to-peer harnessing the benefits of a disruptive technology
... shared database: organized manual, organized mechanical, and volunteer manual The classic case of an organized manual database is the original Yahoo! directory This database was filled by organizing ... case of Napster, metadata means the combination of artist and song names that users search for It also includes additional data managed by the central Napster server, such as the names and Internet ... nodes speak to one another?" ask, "Who owns the hardware that the service runs on?" The huge preponderance of the hardware that makes Yahoo! work is owned by Yahoo! and managed in Santa Clara The...
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ecstasy the complete guide a comprehensive look at the risks and benefits of mdma
... fourths of these therapists stated that their patients had improved greatly in insight-based therapies and that the overall psychological value of MDMA was great (Harlow and Beck 1990) Any psychiatric ... successful treatment, a safe and versatile new medication had been discovered and added to the armamentarium Therapists had found a way to make painful psychotherapy easier and faster MDMA had been ... medical use" and a "high potential for abuse"), clinical research into the nature of the MDMA experience has been meager Amid the furor about the dangers of MDMA abuse have been the claims of psychotherapists...
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Báo cáo khoa học: " The Antinociceptive and Anti-inflammatory Effect of Ethylacetate Extracts from Bang-Poong (Radix ledebouriellae) on the Freund’s Adjuvant-Induced Arthritis in Rats" pot
... value was calculated by these equations; (1) Area of soft tissue = [whole area of paw] － [bone area] (2) Area of soft tissue swelling = [area of inflamed soft tissue] － [area of normal soft tissue] ... withdrawal behavior or (2) vocalization The mechanical threshold in normal animal was ranged from 140 to 160 g The test was duplicated at intervals and mean value was applied to analyze Thermal ... extracted from whole BP and antinociceptive and anti- inflammatory effect on experimentally evoked RA in rats was demonstrated Materials and Methods An im a ls Male Sprague-Dawley rats (the Laboratory...
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Báo cáo y học: "Biology of recently discovered cytokines: Discerning the pro- and anti-inflammatory properties of interleukin-27" pptx
... family of cytokines Annu Rev Immunol 1997, 15:797-819 Yoshida K, Taga T, Saito M, Suematsu S, Kumanogoh A, Tanaka T, Fujiwara H, Hirata M, Yamagami T, Nakahata T, et al.: Targeted disruption of ... O’Shea JJ, Gadina M, Schreiber RD: Cytokine signaling in 2002: new surprises in the Jak/Stat pathway Cell 2002, Suppl: S121-S131 Takeda A, Hamano S, Yamanaka A, Hanada T, Ishibashi T, Mak TW, ... 54 Yamanaka A, Hamano S, Miyazaki Y, Ishii K, Takeda A, Mak TW, Himeno K, Yoshimura A, Yoshida H: Hyperproduction of proinflammatory cytokines by WSX-1-deficient NKT cells in concanavalin A- induced...
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Báo cáo y học: "Anti-Inflammatory mechanisms of the proteinaseactivated receptor 2-inhibiting peptide in human synovial cells" ppt
... 5’-GTCAGGG GAGATCATCGG-3’ and antisense, 5’-GCCCAGTACTTATTCCCT-3’; and GAPDH sense, 5’-CAAGGCTGAGA ACGGGAAGC-3’ and antisense, 5’-AGGGGGCAGAGATGATGACC-3’ The PCR was carried out with μl of template ... Activation of proteinase-activated receptor in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing cartilage degradation: a basic science study Arthritis ... demonstrated a potential application of a PAR-2 inhibitory strategy that may slow down the OA disease progression and reduce patient symptoms Abbreviations OA: osteoarthritis; PAR: proteinase-activated...
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Báo cáo y học: "Topical anti-inflammatory activity of Polygonum cuspidatum extract in the TPA model of mouse ear inflammation" docx
... Mitutoyo America, Aurora, IL) before and at h and 24 h after TPA administration The micrometer was applied near the top of the ear distal to the cartilaginous ridges At 24 h each animal was sacrificed ... each test group was justified on the basis of a pilot experiment showing that the sample standard deviation (s) for measurements of ear edema was about 5% of the measured value and the average ... infiltration and edema in the TPA model of ear inflammation [43] Products of arachidonic acid metabolism such as PGI2 and LTB4 increase vascular permeability leading to edema during the inflammatory...
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Báo cáo y học: "Anti-inflammatory effects of the gorgonian Pseudopterogorgia elisabethae collected at the Islands of Providencia and San Andrés (SW Caribbean)" potx
... medication for a period of days prior to donation Informed consent was obtained from all participants Topical anti- inflammatory activity Topical anti- inflammatory activity of the extracts and fractions ... important events related to the topical inflammatory process i.e oedema formation, and MPO release to the oedema tissues Topical anti- inflammatory activity and tissue MPO assay The evaluation of the ... where appropriate P < 0.05 was considered as indicative of significance using GraphPad Software, Prism V 4.0 P elisabethae anti- inflammatory activity in vivo evaluation The TPA-induced ear oedema...
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Báo cáo khoa học: " Air embolism as a cause of the systemic inflammatory response syndrome: a case report" pps
... catheter, approximately 20 hours after the removal of the introducer, the patient’s cardiac index was elevated and the systemic vascular resistance was low These parameters normalized during the ... vascular resistance, tachypnea, fever and diffuse intravascular coagulation) was compatible with the diagnosis of SIRS The rapidity of the patient’s recovery, as well as the lack of positive cultures, ... clinical diagnosis of diffuse intravascular coagulation The patient was transfused several units of packed red blood cells, fresh frozen plasma, platelets and cryoprecipitate Intravenous antibiotic...
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Báo cáo y học: "A multicentre case-control study of nonsteroidal anti-inflammatory drugs as a risk factor for severe sepsis and septic shock" docx
... investigator All NSAIDs and aspirin were considered However, when aspirin was taken as an antiplatelet aggregant for the prevention of cardiovascular diseases (
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