... However, in the presence of CX, the amount of Egd2 was decreased in both the wild-type and rsp5 mutant cells after the temperature upshift There was no significant difference in the amounts of other ... proteasome involved in the degradation of ubiquitinated substrates [25] Next, to further examine the role ofthe proteasome in degradation of heat-labile Egd2, we analyzed the stability of Egd2 at 25 ... 1) The activity of Rsp5 is indispensable to regulate the expression of many proteins at the transcriptional and post-translational level, because Rsp5 is known to regulate the activity of the...
... simple bit of word salad stands out at once as indicative of profound and specific disorder within the writer As in the words ofthe schizophrenic, so in the behavior ofthe psychopath there seems ... frame them in a scheme of psychopathology The terms I shall use to describe them may often imply that they are blamed for what they or suggest an attitude of distaste or mockery for some of their ... psychopaths for want of a better 14 THE MASK OF SANITY word, are, as a matter of fact, the problem of juries, courts, relatives, the police, and the general public no less than ofthe psychiatrist...
... terms of durativity, and not of atomicity 498 John drank a glass of beer In (9), the development ofthe drinking event can be measured along the subparts ofthe glass of beer Each subpart ofthe ... structure of one of their arguments (which he calls incremental theme) • *The soldierfinished crossing the border The soldiers finished crossing the border *John finished slamming the door open ... associate with the CONST qualia role of chambre such a collection of instances ofthe movable_phys obj type, the CONST role describing the meronymic constitution of a type In fact, the ability...
... pocket unstable because ofthe elasticity introduced The size ofthe S1 subsite may also be reduced as the result of shrinkage ofthe hydrophobic side chains in the surface ofthe S1 pocket which ... side chains, the surface ofthe S1 subsite may become inaccessible to the solvent, which would cause reorientation ofthe side chain of Ser directly away from the hydrophobic surface ofthe S1 subsite ... rearrangement ofthe S1 subsite induced by the interaction between the SH group and the imidazole nitrogen of His397 stabilizes the transition state X-ray crystallography ofthe mutant enzymes and their...
... ofthe claim in question is then construed, and the differences between the state ofthe art and the inventive concept ofthe claim are identified This then enables the examiner to approach the ... in the state ofthe art after the filing date The relevant date for complying with the requirement for sufficiency is the filing date ofthe application and not eg the date of publication ofthe ... characteristics ofthe biological material as is available to the applicant and the specification gives the name ofthe culture collection and the accession number ofthe deposit The information about the...
... temperature-independent part ofthe boundary resistivity whereas the ρ1 to the temperature-dependent part The problem was not, however, the determination of n, D or D but their physical foundation The procedures ... the ratio lG = LS /LA ofthe linear extents LS , determined on the basis ofthe grain domain perimeter G − length (in unit of image size) and LA , determined on the basis ofthe grain domain area ... moment there is no way to prove that D really corresponds to the true boundary resistivity For the purpose ofthe first approximation, we must adopt the asumption that the D, estimated by the procedure...
... measured the protein content ofthe CFMYP and EGMYP bands by densitometry ofthe SDS ⁄ PAGE gel ofthe purified MYP, and the ratio of CFMYP to total MYP (CFMYP + EGMYP) was calculated (Fig 3B) In the ... at stage is still bound to MYP On the basis ofthe results ofthe present study and others, we propose a model for the synthesis and accumulation of MYP and its involvement in zinc transport ... part ofthe zinc in the immature gonads is bound to MYP The elution patterns of zinc were similar in the ovary and testis, but the zinc peak in the immature ovary was larger than that in the immature...
... of one edge ofthe metal-thiolate cluster to the surrounding environment [7–9] Upon incorporation ofthe incoming Cd2+ ion into the metal-thiolate cluster at the crevice site, rearrangement of ... coil around the metal-thiolate cluster, which is shown in the spacefilling model as located in the center ofthe domain Metal exchange of Zn4a-rhMT 1a with Cd2+ The exchange reaction ofthe Zn-substituted ... sequence ofthe a domain of human MT 1a showing the connectivities ofthe four divalent metal cations to the 11 cysteinyl sulfurs (B) Isolated Cd4(Scys)11 cluster present in the a domain of human...
... complex]) with the presence of a minority of active complexes at the beginning ofthe reaction (multiple turnovers ofthe most efcient complexes are then limited by the high stability ofthe IN DNA ... product The stability of IN during the time-course ofthe reaction and the inuence of protein aggregation are discussed Results General features ofthe 3Â-end processing kinetics The kinetics of 3Â-end ... product to the catalyst is not clear In the case of IN, tight binding ofthe protein to recessed viral DNA ends is obligatory in the context ofthe HIV replication cycle: the 3Â-processing of viral...
... [23] of SiC, the emission peak for b-SiC nanowires is obviously shifted to the blue The emergence ofthe peak with a blueshift is due to the existence of oxygen defects in the amorphous layer, the ... composed of Si, C and small amount of O It is found that the molecular ratio of Si/C/O ofthe nanowires is about 3:2:2, which corresponds well to the standard SiC and SiO2 The small quantity of oxygen ... intense possibly due to the SiO2 outer layers ofthe SiC nanowires; this confirms the composition of nanowires To investigate PL properties ofthe synthesized b-SiC nanowires, the corresponding measurement...
... is therefore the measure ofthe minimum number of bits that is required to communicate the information about the entire inventory through the transmission channel The lower the value of FE the ... number of bits that is used by the constituent consonants ofthe inventory 106 Figure 1: The process of computing RR for a hypothetical inventory in terms of a ratio The process of computing the ... comparing the RRs ofthe real and the random inventories The results show that 107 Figure 2: The scatter-plot ofthe redundancy ratio RR of each ofthe consonant inventories (y-axis) versus the inventory...
... (designated R4) in the construct F2 resulted in the abolishment of 80% ofthe relative luciferase activity, despite the presence of exon and the upstream sequence (Fig 3A) A further deletion in ... from the F1 fragment that contained the upstream regulation region, exon and kb ofthe Rnf33 intron; the sequences were cloned in front ofthe promoter-less luciferase gene of pGL-Basic In the ... construct F3 confirmed the importance of R4, albeit with possible further contribution outside the R4 sequence When one to three copies ofthe 305-bp R4 sequence were cloned in either the forward or...
... dimensional, then C X fails to have the fixed-point property Dhompongsa et al studied the fixed-point propertyof complex C∗ -algebras in and obtained the following result Theorem 1.6 see 8, Theorem 1.4 The ... Point Theory and Applications We now show that some ofthe unital uniformly closed subalgebras of C X fail to have the fixed-point property by using the concept of peak points for these algebras Theorem ... spaces have the fixed-point property Let A be a unital algebra over F with unit and let G A denote the set of all invertible elements of A We define the spectrum of an element f of A to be the set...
... controls, ” Journal of Computational and Applied Mathematics, vol 211, no 1, pp 1–10, 2008 S Ahmad, “On the nonautonomous Volterra-Lotka competition equations,” Proceedings ofthe American Mathematical ... vol 74 of Mathematics and Its Applications, Kluwer Academic Publishers, Dordrecht, The Netherlands, 1992 M Kaykobad, “Positive solutions of positive linear systems,” Linear Algebra and Its Applications, ... Equations Proof of Theorem 1.2 The following lemma can be found in 10 Lemma 2.1 Assume that A > and y > 0, and further suppose that (1) y n ≤ Ay n B n , n 1, 2, 2.1 Ai B n − i − 2.2 Then for...
... permeability and permittivity ofthe composite medium, c the velocity of EM waves in free space, f the frequency ofthe microwave, and d the thickness ofthe absorber The reflection loss is related ... is either ofthe real part and imaginary part ofthe complex permittivity e and complex permeability l Ue, Ui, Um correspond to the parameter ofthe effective medium, the insulator, and the semiconductor ... inclination angle of these NWs (indicated with arrows) in the composites is different, leading to the randomly oriented NWs in the composites, and the volume proportion of NWs close to the surface...
... are the reflections of this point in the midpoints ofthe sides of ABC Therefore, the triangles ABC and A2 B2 C2 are centrosymmetric B2 A2 A1 C B1 C2 A B C1 Fig Note also that the center of perspective ... PROPERTYOFTHE JERABEK HYPERBOLA AND ITS COROLLARIES 55 Statement Let P be a point on the Euler line of ABC, A1 B1 C1 be the circumcevian triangle of P , and A2 , B2 , C2 be the reflections of ... in the midpoints of BC, CA, AB, respectively Then the lines AA2 , BB2 , CC2 are concurrent Proof The isogonal conjugate, Q, of P lies on the Jerabek hyperbola Let CQ meet the circumcircle of...
... Cauchy, then A and B have an unique common fixed point Proof By definition 1.3, we deduce that two non-compatible self-mappings of (X, d) satisfy theproperty (E.A) Hence, by Theorem 2.5, the proof ... point of A and B Now, if AX is a complete subspace of X , then there exists x X such that Axn Ax and hence lim d(Ax, Axn ) = Since AX BX , there exists u X n such that Ax = Bu and then the ... X , (2) A and B satisfies theproperty (E.A) If BX is closed in X , then A and B have an unique common fixed point Proof Since A and B satisfy theproperty (E.A), there exists a sequence {xn...
... the changes in these two constant values would lead to a better understanding ofthe changes in the Ea Observation ofthe trend ofthe curve-line from the left (L-shifted) to the right (R-shifted), ... together with the infinitetemperature viscosity constant, represents the fundamental value ofthe Ea constant The stability ofthe viscosity – temperature observation is best indicated by the ... reduction ofthe viscosity is greater at the initial stage ofthe temperature increment, and subsequent increases in the temperature during the latter part had less influence on reducing the viscosity,...
... ul−s to ui along the outer cycle is a shortest path between u0 and ui , as desired In what follows, we give the proof ofthe main theorem Proof of Theorem 2: By Proposition 4, there exists a shortest ... this note, we prove the following theorem Theorem For any integer k and n > 6k , GP (n, k) is not distance-balanced Theorem gives a positive answer to Conjecture The Proof of Theorem First we give ... then there exists a shortest path between u0 and ui which passes through the edge u0 v0 first the electronic journal of combinatorics 16 (2009), #N33 Proof By symmetry, we only need consider the...