the ability of the ventricles to generate blood flow and pressure is derived from the ability of individual myocytes to shorten and generate force myocytes are tubular structures during contraction the muscles shorten and gene
... of capillaries, are visible [24] The adherence of leucocytes in endotoxaemia is a multistep process After the increase in margination of leucocytes fromthe centre ofthe bloodstream, cells are ... group), the differences between the two groups of septic animals must result from dopexamine administration To interpret the results ofthe study it is important to be aware of some limitations ofthe ... aim of this model isto induce manifestations that are characteristic of sepsis Because the animals in the two endotoxaemic groups were treated in an identical manner (with the exception of dopexamine...
... scanned The ovary was identified, and color signals were used to detect the area with the highest bloodflow within the corpus luteum Bloodflow was identified in the peripheral area ofthe corpus ... operating characteristic curve (ROC) analysis was performed to determine the cutoff value ofthe CL-RI providing the best value ofthe sensitivity andthe specificity for determination of normal luteal ... substrate of NO, increases hepatic and limb bloodflow [27,28] In the present study, in order to examine the role of luteal bloodflow in the regulation of luteal function, we investigated whether...
... in this way the histology oftheblood falls into a vicious circle, of which the new phase ofblood histology affords many examples And it is characteristic of this kind of work that fromthe ... measure for the depth of colour oftheblood There are a number of instruments of this kind, of which the "hổmometer" of Fleischl, and amongst others, the "hổmoglobinometer" of Gowers, distinguished ... death ofthe red blood corpuscles, that isofthe old forms, leading to a coagulation necrosis ofthe discoplasm The latter takes up, as isthe case in coagulation necrosis, the proteids ofthe blood, ...
... method to examine the endothelial cell biology ofthe mouse, and will accelerate the molecular and cellular analysis of ECs and their heterogeneity in various vascular beds 1994 Construction ofthe ... this problem Therefore, the isolation and maintenance of murine endothelial cells from various developmental stages and locations is important for dissecting molecular and cellular mechanisms of ... signal sequence ofthe Pgk gene, and a portion ofthe multiple cloning site of pMCS5 XhoI–EcoRI-digested tsA58T Ag cDNA was blunted and cloned into the SwaI site of pCGX, andthe direction was...
... factor for the development of cardiovascular disease including atherosclerosis The major risk factors for the development of atherosclerosis are hypercholesterolemia and elevated levels of low-density ... consumption andthe risk of coronary heart disease in men New England Journal of Medicine, 328, 1450 Salisova, M., Toma, S., & Mason, T J (1997) Comparison of conventional and ultrasonically assisted ... glucose and xylose, constituents The band at 2926 cm−1 is associated with the vibrations of C–H bond The band at 991 cm−1 is associated with the presence of -pyran ring, which indicated the presence...
... Estimation ofthe mechanical property of meniscus using ultrasound: examinations of native meniscus and effects of enzymatic digestion J Orthop Res 2007, 25:884-893 Nishitani K, Nakagawa Y, Gotoh T, ... evaluation of living human cartilage ofthe elbow and knee during mosaicplasty for osteochondritis dissecans ofthe elbow: an in vivo study Am J Sports Med 2008, 36:2345-2353 Page of (page number ... Hattori K, Habata T, Yamaoka S, Aoki H, Morita Y, Takakura Y, Tomita N, Ikeuchi K: Measurement ofthe mechanical properties of regenerated articular cartilage using wavelet transformation In Tissue...
... The factor axis mainly characterized the individuals from Paris due tothe presence ofthe Bg and Mb blood factors, the absence of Ma and heterozygosity at the hemoglobin locus The factor axis opposes ... variability of introduced mouflon populations Genetic variation and discussed in relation tothe history ofthe introductions (origin and number of founder individuals) on the genetic structure are ... took place in the years 1950-1965 and wild-living populations are now present in the mountains ofthe Alps, the Pyr6n6es, the C6vennes andthe Massif Central The genetic variability ofthe Corsican...
... sequestrectomies had to be performed on the patient Due to a hard estimation ofblood loss and duration ofthe whole procedure, this kind of surgery is considered high risk On admission, the boy had the ... Although the concept of classical SCD triggers is less important today, the effect ofthe disease on the carrier’s vascular system determines the aetiology ofthe disease Patients are at risk in the ... the activation of endothelial factors, immunological responses and other factors modulate the onset and course ofthe disease and influence its pathophysiology Nevertheless, there is a consensus...
... according tothe Omani idiom of distress) and examines whether the patient's dissociative state correlates with functional abnormality in specific regions ofthe brain The case is discussed from an ... disorders, it will prove to be even more difficult to establish whether such defects are truly representative ofthe pathology or are simply by-products of a compensatory adaptation tothe distressed ... type, in which the spirit andthe human being have a 'platonic' form of relationship The second type of possession is a partial possession that is reminiscent of dissociative identity disorders in...
... oversaw the project running and data analysis, and drafted the manuscript TM, SF, YI, YK, and HM assisted in the study design and coordination, and oversaw the data analysis and drafting ofthe manuscript ... CD204+ macrophages in the skin andthe CD14brightCD163+CD204+ monocyte subset in the peripheral circulating bloodare involved in the pathogenesis of SSc Page of 10 trols, 22 disease-free volunteers ... activation of monocytes As CD14brightCD163+CD204+ cells were not apparent in PBMCs from healthy controls, the presence of this monocyte subset may be highly specific to this disease Taken together, this...
... 50% ofthe causes of death in patients with advanced vasodilatory shock [5] Considering the heart as the obviously most vulnerable link ofthe cardiovascular chain, it must be one of our goals to ... useful tool to achieve this critical balance [10] A putative mechanism by which supplementary AVP infusion may exert beneficial effects isthe significant reduction of high, potentially toxic ... perfusion is difficult but crucial to guarantee optimal patient outcome in vasodilatory and septic shock Competing interests The authors declare that they have no competing interests Page of (page...
... previously established in the dog [21,30] After cannulation ofthe carotid artery for bloodpressure monitoring, a midline laparotomy was performed andthe inflow vessels tothe liver dissected The gastroduodenal ... raised tone [HAP 156.2 (4.8) and PVP 2.3 (0.7) mmHg] The addition of 8-SPT tothe hepatic arterial and portal venous In vivo studies are required to confirm whether ATP is involved in the generation ... Diagram 1of silastic H-shaped prosthesis inserted into the portal vein andthe inferior vena cava ofthe in vivo rabbit model Figure Diagram of silastic H-shaped prosthesis inserted into the portal...
... transfusion ofblood products, hypothermia, acidosis and shock As Fresh Frozen Plasma, coagulation factors and other pharmacologic therapies are administered, it isof great value to monitor the effects ... appropriate for blood product administration are being developed [56,57] The most promising of these criteria arethe TASH Score from German investigators andthe ABC Score from Cotton and coworkers ... FFP:PRBC ratio and prevented them from transitioning tothe high ratio group These observations are also reflected in a paper fromthe Stanford group by Riskin and coworkers Riskin and others identified...
... included the age ofthe RBC unit at the time of transfusion andthe leukodepletion status The age oftheblood was determined by subtracting the date of collection fromthe date of transfusion The ... received fromthe Australian Red Cross Blood Service, and in-kind support fromthe Australian and New Zealand Intensive Care Research Centre The present study is a collaboration ofthe Australian and ... in risk Therefore, because ofthe limitations ofthe previous studies andthe public health importance of this issue, we considered it desirable to conduct a prospective, multicenter study to...
... types In this study we compare the proteomes of mDCs, moDCs and KG-1 cells, and then attempt to relate this tothe functional properties of these cells Figure shows the workflow andthe way in ... down-regulated) in the DC models compared to mDCs, were excised fromthe gels and subjected to trypsin digestion and MALDI-TOF (matrix-assisted laser desorption/ionisation-time of flight) mass spectrometric ... CBA and analyzed using the cytometric CBA analysis software; with further analysis in Excel Data shown arethe means of triplicate experiments A Student t-test was carried out to determine the...
... parameter: The race of change ofthe SI in LV cavity and myocardial tissue duringthe first pass of contrast agent b) Time to peak: The time fromthe onset of contrast enhancement (the foot ofthe SI ... at the aortic root, andthe ascending aorta as well as in the descending aorta at the level ofthe aortic isthmus and above the diaphragm in patients and controls The systolic and diastolic blood ... this anatomical condition, the coronary arteries are abnormally connected tothe heart chambers or great vessels In 90% the fistula drains into the cavum ofthe right ventricle (Perloff 2003) The...
... hydrogen atom and one oxygen atom ofthe side chain carboxylic group of Glu668 and between the carbonyl carbon atom of Pro ofthe substrate Ala-Pro-pNA andthe Ser630 oxygen atom ofthe enzyme to hold ... in comparison tothe formation ofthe EI complex Moreover, for this peptide binding tothe competitive binding site of DP IV is diminished (c ¼ 9.2) in comparison tothe other peptides The peptide ... carbonyl group of Val4 ofthe peptide andthe backbone amide hydrogen of Ala743 ofthe enzyme, between the side chain carbonyl group of Asn7 of Tat(1–9) andthe side chain of Lys554 of DP IV and finally,...
... acquired theabilityto inhibit the e isoform, whereas peptide was only effective on the b1, e and f isoforms Interestingly, the inhibitory action of peptides and on the b1 isoform was found to be ... activity ofthe a, b1 and b2 isoforms [13] The present study aimed to identify peptides derivedfromthe amino acid sequence ofthe PKI55 protein to be used as pharmacological tools The effects ofthe ... inhibition ofthe PKC a, b1, b2, c, d, e and f isoform enzyme activity in the presence ofthe PKI55 protein andthederived peptides 5, and 9, all tested at a concentration of lM The data arethe mean...
... nutritional issues that are raised during consultation should be addressed duringthe risk analysis process CONSISTENCY 25 A consistent approach should be adopted to characterise and manage safety and ... measured are comparable RISK MANAGEMENT 16 Risk management measures for foods derivedfrom modern biotechnology should be proportional tothe risk, based on the outcome ofthe risk assessment and, ... consistent with the provisions ofthe SPS and TBT Agreements The application of product tracing tothe areas covered by both Agreements was considered by the Codex Committee on Food Import and...