... based on clinicalpractice guidelines Our research questions are: How should clinicalpractice guidelines be adapted to elicit individual patients’ preferences andto support patients’ and health ... How to integrate individual patient valuesand preferences in clinicalpractice guidelines? A research protocol Implementation Science 2010 5:10 Submit your next manuscript to BioMed Central and ... For example: How should clinicalpractice guidelines and patient decision support technology be linked, and what are barriers and facilitators for doing so? What types of clinical decisions are...
... based on clinicalpractice guidelines Our research questions are: How should clinicalpractice guidelines be adapted to elicit individual patients’ preferences andto support patients’ and health ... How to integrate individual patient valuesand preferences in clinicalpractice guidelines? A research protocol Implementation Science 2010 5:10 Submit your next manuscript to BioMed Central and ... For example: How should clinicalpractice guidelines and patient decision support technology be linked, and what are barriers and facilitators for doing so? What types of clinical decisions are...
... ER, Antunes T, Barros JM, Okamoto V, Borges JB, Amato MBP, Carvalho CRR: Mechanical ventilation in acute respiratory failure: recruitment and high positive end-expiratory pressure are necessary ... inflammatory mediators in patients with acute respiratory distress syndrome; a randomized controlled trial JAMA 1999, 281:77–78 Gattinoni L, Caironi P, Pelosi P, Goodman LR: What has computed tomography ... stratified the 53 patients of the trial into quartiles according to PEEP levels and analyzed the 28-day survival rate A PEEP of more than 12 cmH2O, and particularly greater than 16 cmH2O, was...
... transplantation, and mathematics in hepatology We have encouraged the use of tables and gures to aid interpretation and understanding The scientic information is current and exhaustive and is essential for clinical ... highlighted in the text TTOA01_vol1 3/12/07 4:44 PM Page iii TEXTBOOK OF Hepatology From Basic Science toClinicalPractice THIRD EDITION SECTIONS 110 AND INDEX EDITORS ASSOCIATE EDITORS Juan Rodộs MD ... attaching to the stomach is also called the hepatogastric ligament, and that attaching to the duodenum, the hepatoduodenal ligament In addition, peritoneal folds can extend from the liver to the...
... oligomers The proto-fibril of Ab was shown by AFM to be a slightly curved, of 4–11 nm diameter and < 200 nm long [56] Isolated protofibrils were found to be toxic, causing oxidative stress and, eventually, ... tendency to aggregate in vitro An interesting observation was made that PrPC (the normal, cellular protein) binds to survival factors and that the PrPC to PrPSc transition might result in apoptotic ... of the ˚ fibrils are [58], b strands (separated by 4.7 A) running perpendicular to the long axis of the fibrils and b sheets extending parallel to this axis The b strands form a ˚ b helical twist...
... serotonin and vasopressin, and vasodilators such as -adrenoceptor agonists, vasoactive intestinal peptide and calcitonin generelated peptide These agents act by binding to receptors that couple to heterotrimeric ... Growth factors Vascular growth factors are potent chemoattractants and mitogens Factors such as platelet-derived growth factor (PDGF) and basic Wbroblast growth factor (bFGF) are thought to play ... estimated to bind to proteins or to be taken up into stores (Kamishima and McCarron, 1996) Despite this, opening of Ca2+ channels causes [Ca2+]i to rise to micromolar levels This is suYcient to activate...
... pain receptors induced by peripheral nerve injury Science 251:1608–1610 46 Sato K, Ohtsuyama M, Sato F (1993) Normaland abnormal eccrine sweat gland function In: Low PA (ed) Clinical Autonomic ... IL-1 to its receptor and can be found in high concentrations in keratinocytes Mice deficient in IL-1ra have been shown to be more susceptible to lethal endotoxemia and this cytokine is thought to ... Section II: Stress and Cutaneous Immunity Neuroanatomy of the Skin D Metze Neuroreceptors and Mediators S Ständer and T.A Luger 13 Autonomic Effects on the Skin F Birklein and T Schlereth...
... a Values for Xao and Xan are relative to Guo and Gua, respectively, at pH b Values of Vmax and Vmax/Km at pH 5.7 and pH 6.5 are relative to those at pH ¼ c 12 ± lM in [31] d Values of kcat and ... 33 ± s)1 and 2.8 ± 0.5 s)1ÆlM)1, and 43 ± s)1 and 3.1 ± 0.6 s)1lM)1 for Guo and Gua, respectively (cf Stoeckler et al [31]) e 11 lM in [61] f Values of kcat and kcat/Km are 31 ± s)1 and 2.8 ± ... salvage pathway and the differences in structure between the neutral and monoanionic forms of these relative to those of Hx and Ino, and Gua and Guo, it is clearly desirable to determine the...
... ECC and FSR, FSR and KT/V and between ECC and K, equations (39), (40) and (42), respectively, follow directly from their definitions and are valid for all reference methods and any patient and ... derived from fitting toclinical data 12 Progress in Hemodialysis – From Emergent Biotechnology toClinicalPractice 3.2 Urea KT/V and creatinine clearance for the kidneys To assess the residual ... respectively, Fig and Table The amplitude of urea concentration changes had the highest values for HD3x and the lowest for HD6xn, Fig and Table The weekly values of ECC and FSR, according to all methods...
... were to be approved as a practice guideline, how likely would you be to apply the recommendations to your patients? Intentions to use in practice Intentions to use with patients *Items 1, 20, and ... assess the extent to which various factors are influenced by time Understanding this will provide greater direction regarding efforts to promote utilization of CPGs into practiceand healthcare ... cancer system defined by data and monitoring of system performance, evidence-based knowledge and best practices, transfer and exchange of this knowledge, and strategies to leverage implementation...
... were to be approved as a practice guideline, how likely would you be to apply the recommendations to your patients? Intentions to use in practice Intentions to use with patients *Items 1, 20, and ... assess the extent to which various factors are influenced by time Understanding this will provide greater direction regarding efforts to promote utilization of CPGs into practiceand healthcare ... cancer system defined by data and monitoring of system performance, evidence-based knowledge and best practices, transfer and exchange of this knowledge, and strategies to leverage implementation...
... result of its translation into many other languages, including Spanish This version was already tested in Spain and it proved to be reliable and feasible to apply [13] A total of 30 health professionals ... interpreted the data, and helped to draft the manuscript ECh, RM and RB appraised guidelines, interpreted the data and helped to draft the manuscript All the authors read and approved the final ... Lopez-Olivo and Dr Jeremy Grimshaw for their support to this research andto both reviewers for their invaluable feedback 21 References 23 10 Definitions of Key Terms In ClinicalPractice Guidelines:...
... patients on day one, and decreased to 110 patients on day seven, due to interruptions to enteral nutrition and/ or extubation in some patients Secondary endpoint: factors suspected to influence enteral ... observational study, and it is impossible to take into account all confounding factors Conclusions This study is in line with efforts at European level to evaluate professional practices, and quantify ... to influence enteral nutrition, and contribute to non-adherence to feeding guidelines: hospital type, use of a local nutrition protocol, sedation, vasoactive drugs, number of interruptions, and...
... implementation activities and how to work together to better encourage the adoption of their guidelines into routine practice Based on the findings of Grimshaw and colleagues, it is reasonable to continue ... current date and are of interest to the CMA membership At present, there are no quality criteria applied to screen the guidelines that are admitted to the repository The CMA assigns English and French ... dichotomized into two six year periods 1994–1999 (previously published by Graham and colleagues[5]) and 2000–2005 To investigate whether the volume of guidelines a developer produces is related to...
... will need to develop relevant goals and objectives Goals and objectives offer a general focus, clarify expectations for learning and attainment, and relate them to residents' clinicaland didactic ... knowledge and adherence toclinicalpractice guidelines In Evidence Based ClinicalPractice newsletter McMaster University; 2008:12 Bachman KH, Mazur DJ: Using practice guidelines to teach residents ... CI 0.22 to 0.88) Teaching how to deal with conflicting CPGs was associated with female gender of the program director (OR = 2.00; 95% CI 1.17 to 3.38), and inversely associated with 26 to 50%...
... taxonomy to classify barriers and facilitators[27] This taxonomy had been developed and used to abstract data from previous studies on barriers and facilitators to implementing clinicalpractice ... pertaining to the assessment of barriers and/ or facilitators to the implementation of best practices in clinical practice[ 42,52] Designs of study within which barriers and facilitators elicited ... difficult to understand andto put into use [30] Lack of visibility of the results of using SDM [30] Perception that it is not possible to create and share information with one another in order to reach...
... implementation activities and how to work together to better encourage the adoption of their guidelines into routine practice Based on the findings of Grimshaw and colleagues, it is reasonable to continue ... current date and are of interest to the CMA membership At present, there are no quality criteria applied to screen the guidelines that are admitted to the repository The CMA assigns English and French ... dichotomized into two six year periods 1994–1999 (previously published by Graham and colleagues[5]) and 2000–2005 To investigate whether the volume of guidelines a developer produces is related to...
... will need to develop relevant goals and objectives Goals and objectives offer a general focus, clarify expectations for learning and attainment, and relate them to residents' clinicaland didactic ... knowledge and adherence toclinicalpractice guidelines In Evidence Based ClinicalPractice newsletter McMaster University; 2008:12 Bachman KH, Mazur DJ: Using practice guidelines to teach residents ... CI 0.22 to 0.88) Teaching how to deal with conflicting CPGs was associated with female gender of the program director (OR = 2.00; 95% CI 1.17 to 3.38), and inversely associated with 26 to 50%...
... and anatomical factors predisposing to the chronic inflammation and bacterial presence [227] Most of these patients will need to be referred to an otolaryngologist for assessment of disease and ... responding to first-line therapy A careful history to assess likelihood of resistance should be obtained, and should include exposure to antibiotics in the prior months, exposure to daycare, and chronic ... reported Topical INCS thus appear to be safe andto afford an additional benefit when antibiotics are used Oral decongestants have been shown to improve nasal congestion and can be used until symptoms...