... 2008, 3:9 Statistics The microsoft excel program was used for the creation of the graphs and the SPSS program 12.0 (SPSS Inc, Chicago, IL, USA) for the creation of statistics Data analysis was conducted ... in order to improve the biomechanical properties of thetechnique [20] Rowland and Burkhart [21] gave an emphasis on the mathematical need to put the transverse hole for the figure-of-eight tension ... formed the study group The fracture pattern was assessed using the Mayo classification [4] which takes into account the degree of fracture displacement and comminution as well as the stability of the...
... stem cells as they undergo chondrogenesis and that this has important implications for the use of the IPFP in cartilage tissue engineering Competing interests The authors declare that they have no ... and performed the experiments described in this study, was responsible for tissue procurement and processing, and produced the initial version of this manuscript ABA helped conceive the experiments ... tension was decreased to 1% [51] In the context of these cultures the oxygen concentration is 5% at the surface but is likely to be below 5% towards the centre of the aggregate It has also been noted...
... therefore localised to cells in different regions of the small arterioles The positive staining for 3G5 in the perivascular cells suggested the presence of pericytes in the IPFP tissue Cell isolation ... predominantly the tunica intima consisting of the endothelial layer and the basement membrane, and αSMA (e, f) staining predominantly the tunica media consisting of the muscular layer of the arteriole ... further culture [41-44] Another possibility is that the expression of 3G5 could be due to culture conditions and not the reminiscence and the demonstration of a cell origin, and further work is...
... this case V(K’13’) = K’P I I K for Alternative K’fi being equations to equations estimable (3.2) that not require the inverse of B are The disadvantage of these equations is that (S’R-’S-G) is ... Models are defined to be equivalent if they yield the matrix of y, and E(y) isthe same for both models Let same variance-covariance and V = CGC’ + B which isthe same as (2.3) Thus, a model with ... Let the general linear model be S is assumed to be null, and R is taken to be Ia Another paper could the problem of estimation of S, R and G by either restricted maximum...
... arthroscopy is performed for a lesion within thefatpad Therefore, we believe that puncturing the lesion poses a high potential risk of recurrence Of course, open excision of an infrapatellar fatpad ... (Figure 8A, B) Discussion Ganglion cysts within the knee cavity are rare and usually originate from the cruciate ligaments, the menisci, the alar folds that cover the patellar fatpad [5], Nikolopoulos ... with a history of or signs of mimicking an internal derangement of the knee The differential diagnosis should include meniscal injury, loose body, chondral flaps, osteoarthritis, cyst of menisci,...
... into the scope of the immunologist, dermatologist, allergologist, and occupational-health specialist, as awareness of the multiple effects that xenobiotics can have on the immune system is rapidly ... skin patch testing is high Together with the potential chronicity of this disorder, its effect on the quality of life of those afflicted, and the economic impact this conveys are sufficient indications ... comprehensive picture of the aspects of that metal with many biologically noxious but metallurgically indispensable characteristics This chapter reviews the epidemiology, the prognosis for occupational...
... available to the research scientist—and more and more to the clinically-oriented dermatologist—we were able to widen the scope of this book from theskin surface to the entire skinThisis also reflected ... to the First Edition The fourth volume of our series on Bioengineering of theSkinis devoted to the methods for skin surface imaging and analysis Although theskin as the outermost organ is ... like in VD With this method, the penetration of light into the uppermost skin layers is improved, and the images contain more information The advantage of VD and ELM is that theskinis imaged under...
... To verify that the constructs produce proteins of the expected masses, we attached the V5 epitope to the C terminus of the CRFR1 isoforms (Fig 1C) The predicted masses of the isoforms without/with ... (including tag) of these isoforms is listed in Table Thus, the mRNA from the alternatively spliced CRFR1 forms is translated into final protein products, which are the subject for further post-translational ... HindIII and EcoRI and inserted in thevector described above This plasmid was named pLuc The minimal promoter containing TATA box was amplified from pcDNA6/V5-HisA vector (Invitrogen) by primers...
... tab distance and tab geometry (Vogel, 198Ic) Analysis of the data showed that the higher the ratio of distance between the tabs to the area below the tabs, the higher were the stress values These ... animals, mostly rats, are sacrificed in anesthesia The back skinis shaved and a flap of x em removed Subcutaneous fatis removed from theskin flaps and the sample placed between two pieces of plastic ... as epidermolysis bullosa, in which the mechanical resistance of the BM is reduced In this overview, the synthesis and organization of collagen, elastin, and BM are elucidated Furthermore, alterations...
... function The impact of the parasympathetic nervous system on the skin, however, is of negligible importance in humans Theskinis › › › › This chapter describes anatomy and function of the sympathetic ... produced by the host [48] This ensures a broad but self-tolerant defense The mechanism of this defense depends on the receptor subtype, the cell on which the receptor is expressed, and the receptor’s ... flow The autonomic innervation of theskin mostly belongs to the sympathetic division of the autonomic nervous system The postganglionic nerve fibers run in peripheral nerves to the skin, where they...
... Thus, the method that we have established for the detection of TGase exhibits superior specificity and reactivity TGase expression is not limited to theskin epidermis It is also expressed in the ... for further analysis based on their levels of reactivity Isozyme specificity of the peptide sequences The four sequences with the highest reactivity were further analyzed for isozyme specificity ... keratinocytes [10–12] The CE is located underneath the plasma membrane of differentiated keratinocytes and is essential for barrier function of the epidermis The CE comprises several proteins,...
... Pseudechis australis snake venom LAO (42%) The highest identity (76%) was observed with the apoptosis-inducing protein (AIP) derived from the viscera of mackerel infected with the nematode, Anisakis ... activity of SSAP 130 Discussion This study isthe first to discover an LAO with antibacterial activity in theskin mucus of a teleost and to reveal the involvement of LAO in the innate immunity ... glycoprotein consisting of 75-kDa subunits by SDS ⁄ PAGE, partly because of the scarcity of the protein of interest In this study therefore we isolated the antibacterial protein, SSAP, from theskin mucus...
... with bacterial membranes, although the molecular basis of this action is not well understood To test whether PSKP-1 and PSKP-1K pertain to this group of proteins, they were assayed against E coli ... 1ỵ ẵS EC50 b 4ị where [S] isthe concentration of the sample, EC50 isthe effective concentration that causes 50% of the effect, and b represents the cooperativity of the effect Hemagglutination ... calculated for each concentration of the inhibitor by nonlinear t of the data from the above negative controls; [I] isthe concentration of the inhibitor, IC50 isthe concentration of inhibitor that...
... their activity Another important feature conserved in this group of peptides isthe central Lys-Lys pair and the basic nature of the peptides It appears that the length of the peptide and this ... be addressed is what role these active peptides have in the amphibian integument? The glandular secretion of the animal is exuded onto theskin (and into the gut) when the animal is stressed, ... Limnodynastes interioris) [24] has the sequence GLLSGLGL-OH In this paper, we describethe isolation, sequence determination, and activities of two bioactive peptides from theskin glands of the stony creek...
... mucosa) visualized? If thisisthe case, the lesion should be considered as a melanocytic lesion (Figs. I.3.2, I.3.3, I.3.4) Step 3: If thisis not the case, the lesion should be evaluated for the ... I.3.7.1 Asymmetry The lesion is bisected by two lines that are placed 90° to each other The first line attempts to bisect the lesion at the division of most symmetry and the other one is placed 90° ... within the epidermis and papillary dermis This term is exclusively used in the ABCD rule of dermoscopy and should not be confounded with the term “streaks,” which is used in the 7-point checklist...
... in the safety evaluation of topical ethanol applications This was done in neither of the above mentioned studies about the toxicity of skin disinfectants To our knowledge, the only study in the ... because acetaldehyde is not contained in the products themselves, but only formed from ethanol during use in the oral cavity or on theskin For this reason the maximum value in the European cosmetics ... for other compounds In other product groups - especially hand disinfectants in hospital hygiene -, the advantages for the patients may outweigh the potential risks for the users However, in this...
... technologies, can be developed for individuals across the lifespan and across the globe Thisis an inter-disciplinary task The scientific research community is considerably more accepting of well-being ... enhancing wellbeing is now more feasible and this means that the credibility, value and longevity of well-being research will be enhanced We hope that this new journal will contribute to this positive ... Csikszentmihalyi, Chris Peterson and others Positive psychology has provided an excellent springboard from which to tailor well-being programs and evaluate their efficacy Thisis primarily where...
... excision is possible; and is located on theskin surface, where it is visible The incidence has increased dramatically (6% per year from 1973 to 1980, then 3% per year) Current lifetime risk ... present normally in the epidermis and sometimes in the dermis This tumor affects around 62,000 individuals per year in the United States, resulting in 7910 deaths Melanoma isthe fifth most common ... incidence is inversely correlated with the latitude of residence; at any latitude, darker-skinned persons have the lowest incidence Melanoma is rare in children under age 10 Table 83-1 Risk Factors...
... Superficial spreading melanoma isthe most frequent variant observed in the white population Melanomas arising in dysplastic nevi (see below) are usually of this type The back isthe most common site for ... predominantly a During much of this time, the precursor stage, lentigo maligna, is confined to the epidermis Source: Adapted from AJ Sober, in Pathophysiology of Dermatologic Diseases, NA Soter, HP Baden ... women, on reddish brown, lower legs) and often whitish pink, and the border of lesion is at least in part visibly and/or palpably elevated Nodular melanoma Any 40–50 site Months Reddish to less...
... other in appearance The borders are often hazy and indistinct, and the pigment pattern is more highly varied than that in benign acquired nevi Of the 90% of melanoma patients whose disease is ... unanimity exists regarding their clinical and histopathologic features The observation that sporadic melanomas can arise in association with a clinically atypical mole makes thisthe most important ... other Shape Irregular borders; Round; sharp, clear-cut pigment may fade off into borders between the nevus and surrounding skin; macular the surrounding skin; may be portion at the edge of the...