tdrl 505 prevents entry into s phase 14a h460 cells were treated with 0 8 µg ml nocodazole for 12 hours washed then treated with either vehicle or 100 µm 505 for 4 8 and 12 hours brdu 10 µm was added during the final 2 hours of tre

Regulation of S Phase

Ngày tải lên : 25/10/2013, 21:20

... Cdc6 in ﬁssion yeast (Nishitani and Nurse, 1995; Nishitani et al., 20 0 0), Xenopus egg extracts (Arias and Walter, 20 0 4; Li and Blow, 20 0 4) , and human cells (Vaziri et al., 20 0 3) causes rereplication ... and MCM, associate with oriP of Epstein-Barr virus Proc Natl Acad Sci USA 98: 100 85 – 100 89 Chesnokov I, Remus D, Botchan M ( 20 0 1) Functional analysis of mutant and wild-type Drosophila origin recognition ... dissection of a mammalian replicator in the human beta-globin locus Science 28 1 : 100 5– 100 9 Alexandrow MG, Hamlin JL ( 20 0 4) Cdc6 chromatin afﬁnity is unaffected by serine- 54 phosphorylation, S- phase...

33
472
1

Báo cáo khoa học: Human delta-lactoferrin is a transcription factor that enhances Skp1 (S-phase kinase-associated protein) gene expression pdf

Ngày tải lên : 30/03/2014, 08:20

... localization sequence (NLS) in vivo and in vitro A comparison with the SV 40 large T-antigen NLS J Biol Chem 27 2, 22 1 34 22 139 FEBS Journal 2 74 ( 20 0 7) 20 3 8 20 5 3 ª 20 0 7 The Authors Journal compilation ª 20 0 7 ... pGL3-5 34- DS1Skp1, and pGL3-5 34- DS2Skp1) (2 50 ng per well) and pcDNA-DLf in the range 2 50 100 0 ng per well The functionality of the DLf consensus NLS bipartite sequence was assessed using increasing ... prognostic value of FEBS Journal 2 74 ( 20 0 7) 20 3 8 20 5 3 ª 20 0 7 The Authors Journal compilation ª 20 0 7 FEBS 20 5 1 Delta-lactoferrin enhances Skp1 gene transcription 10 11 12 13 14 15 16 17 18 C Mariller...

16
363
0

threshold of war franklin d. roosevelt and american entry into world war ii

Ngày tải lên : 31/05/2014, 02:06

... destroyers.6 The president set an annual production target of 50, 000 airplanes; Congress raised the authorized strength of the army from 2 80 , 000 to 1, 20 0 ,00 0 and more when feasible The problem was no ... War orders were reviving it Consumer demand was rising; cars were selling Profitable at last, business resisted conversion As profits and the cost of living rose so did labor 's demand for its share ... in the first half of 1 941 And the great Bismarck readied for sea.35 In March 1 941 , Britain was losing ships at the rate of over 500 ,00 0 tons a month, and losses were on the rise U-boats were sinking...

294
635
0

Báo cáo khoa học: "The mental status of 1090 heroin addicts at entry into treatment: should depression be considered a ''''dual diagnosis" pptx

Ngày tải lên : 08/08/2014, 23:20

... 56 .2

6
264
0

Báo cáo y học: " Classic swine fever virus NS2 protein leads to the induction of cell cycle arrest at S-phase and endoplasmic reticulum stress" potx

Ngày tải lên : 12/08/2014, 04:21

... 34. 19%, and G2/M: 4. 96%, whereas for GFP-NS2-expressing SUVEC stable cells, the proportions were G0/G1: 52. 96%, S- phase: 42 .29 % and G2/M: 4. 76%, consistently, for the NS2-GFP-expressing SUVEC stable ... performed in a total volume of 25 μL using a thermocycling protocol of 94 C for min, 94 C for 30 s, 62 C for 30 s and 72 C for 1.5 for 35 cycles, followed by 72 C for 10 The PCR product was purified ... Following two washes with PBS, cells were resuspended in 70% ethanol and fixed at 4 C for 18 h Cells were washed and resuspended in PBS containing 20 μg /mL of RNase A and 50 μg /mL of propidium...

12
303
0

Báo cáo y học: "Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R." pps

Ngày tải lên : 13/08/2014, 01:20

... Retrovirology 20 1 0, 7:59 http://www.retrovirology.com/content/7/1/59 Page 11 of 18 A a b Adv 2N Adv-Vpr Adv Adv-Vpr 11 hrs 4N 8N 40 0 20 0 600 80 0 100 0 40 0 20 0 80 0 100 0 600 33 hrs 20 0 40 0 600 80 0 100 0 20 0 2N ... Retrovirology 20 1 0, 7:59 http://www.retrovirology.com/content/7/1/59 Page 13 of 18 A 48 hrs 72 hrs 96 hrs Adv 40 0 80 0 40 0 80 0 40 0 4N 4N 4N 80 0 Adv-Vpr 2N 8N 40 0 40 0 80 0 2N 8N 2N 8N 80 0 40 0 80 0 DNA content ... 20 0 2N 4N 20 0 40 0 600 80 0 100 0 55 hrs 4N 8N 40 0 600 2N 80 0 100 0 8N 20 0 40 0 600 80 0 100 0 DNA Content C a siRNA Adv siRNA Adv-Vpr 6 * * Ctr 6 * * B p-Chk1 -S3 45 β-actin...

18
183
0

Báo cáo y học: "Polysaccharopeptides derived from Coriolus versicolor potentiate the S-phase specific cytotoxicity of Camptothecin (CPT) on human leukemia HL-60 cells" pps

Ngày tải lên : 13/08/2014, 15:21

... from 0, 10, 100 and 100 0 nM for treatment of five hours, PSP pre -treated cells (25 μg /ml, 72 hours) were also enhanced the cytotoxicity of CPT ( 100 nM) by 30. 12% (Figure 7) In contrast to the ... average size of HL- 60 cells HL- 60 cells were treated with various PSP concentrations (0- 40 0 μg /ml) for 72 hours Average diameter of HL- 60 cells was measured with the Multisizer hours of PSP treatment ... incorporation in the HL- 60 cells was reduced by 77 .2% , 79 .4% and 84 .7% for treatment times of 24 , 48 and 72 hours respectively (Figure 3), suggesting DNA synthesis was reduced in cells exposed...

10
185
0

Báo cáo y học: "he miR-17-5p microRNA is a key regulator of the G1/S phase cell cycle transition" pdf

Ngày tải lên : 14/08/2014, 20:22

... activity 0. 4 miR-17-5p #1 miR-17-5p #2 miR-17-5p #3 0. 8 10nM miR-17-5p 50nM miR-17-5p 0. 6 MTT activity G2 phase Control #1 Control #2 Control #3 0. 6 0. 4 0. 2 0. 2 0. 0 0. 0 20 40 60 80 100 Hours post transfection ... Biology 20 0 8, phase, and entry into S phase The enrichment of all these categories was more than five standard deviations away from what was seen for random sampling of similar sized sets of targets ... S phase G2/M phase G1/G0 phase S phase G2/M phase G1/G0 phase Phase of HeLa cell cycle Figure Phase enriched expression of the miR-17- 92 locus Phase enriched expression of the miR-17- 92 locus...

14
331
0

Insights into solid phase characteristics and release of heavy metals and arsenic from industrial sludge via combined chemical, mineralogical, and microanalysis

Ngày tải lên : 18/08/2016, 15:47

... 5 . 82 37 .4 8. 41 5. 14 40 . 16 3.99 4. 93 38. 71 58. 41 43 .85 38. 47 12 . 84 12. 14 43.76 18 19 20 21 22 23 24 25 26 27 28 29 30 13 .4 13 .21 44 .37 24 .07 24 .06 2. 13 1.33 48 . 77 11 .47 6. 74 26 . 64 51.76 50. 04 3.7 ... 5 ,03 9±51 501 ±6 13, 2 08 ±1 48 4, 656–7 ,2 74 28 , 8 28 133 85 ,00 0±1, 40 0 2 20 P (%) 1.97 0. 09 2. 72 0. 04 6.17 0. 02 NA NA NA NA Cu (mg/kg) 10, 85 1 29 5 42 ± 146 9,7 90 95 NA NA NA 19 ,00 0 S (%) 7. 98 0. 02 2.19 0. 02 ... 1, 727 ±6 5,153±113 5, 600 ±3 60 NA NA 2, 6 80 0 Pb (mg/kg) 122 ±1 8, 1 30 100 2 68 1 NA 42 4 100 ± 14 5, 700 Mn (mg/kg) 42 7± 20 1 68 3 157 2 NA NA NA 2 50 Zn (mg/kg) 72, 347 2, 223 1 ,1 24 ±9 77,3 52 1 ,06 1 NA 1 ,03 6 20 , 100 ± 720 ...

14
339
0

Delta''''s key to the next generation toefl test part 8

Ngày tải lên : 17/10/2013, 20:15

10
454
0

Project Gutenberg’s Philosophy and Fun of Algebra, by Mary Everest Boole This eBook is for the use pdf

Ngày tải lên : 15/03/2014, 00:20

... Teacher s Function 19 The Use of Sewing Cards 21 10 The Story of a Working Hypothesis 23 11 Macbeth s Mistake 26 12 Jacob s Ladder 28 13 The Great x of the World 29 14 Go Out of My Class-Room ... laws of the Logos, because the Logos has the whip hand, and knows its own business, and is master of the situation Therefore children now are allowed to study the laws of the Logos, whenever the ... the world and promoting the fortunes of 23 CHAPTER 10 THE STORY OF A WORKING HYPOTHESIS 24 one s children and grandchildren besides cheating everybody, including one s own nearest relations Therefore...

56
474
0

Prof. Koch''''s Method to Cure Tuberculosis Popularly Treated potx

Ngày tải lên : 15/03/2014, 19:20

... dangerous transition of scrofula into tuberculosis and thus save the lives of a great many persons Anyone who has informed himself through the foregoing as to the great number of diseases and forms of ... Tuberculosis by Max Birnbaum 24 of tuberculosis of the testicles if suppuration sets in The skin is perforated and fistulae are formed If there is no halt in the process, general tuberculosis results ... in the sense of the diseases just considered, still tuberculosis and scrofula have the most intimate relations Scrofula is only too often a precursory stage of tuberculosis The manifold scrofulous...

41
192
0

Báo cáo khoa học: Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138 pot

Ngày tải lên : 16/03/2014, 13:20

... 3.11–3 .00 1537 72. 6 1 .4 30. 0 2. 5 3 32 64 ⁄ 17 40 0.1 98 ⁄ 0. 2 70 0.1 94 75 70 ⁄ 20 ⁄ 80 0 .00 8 1 .4 59 ⁄ 65 ⁄ 37 ⁄ 44 4. 4 30. 0 2. 5 35199 ⁄ 185 6 0. 21 6 ⁄ 0. 28 8 0. 20 3 76 14 ⁄ 20 ⁄ 79 0. 0 08 1 .4 62 ⁄ 68 ⁄ 39 ⁄ 48 ... 139.6, 115 .0, 65.6 30. 0 2. 5 25 1696 37 1 04 99.5 12. 6 0. 089 E138K-PETT -2 SRS PX 14. 2 CCD ADSC-Q4 0. 979 1 38. 8, 1 14 .8, 65.9 30. 0–3 .0 57571 1 909 5 88 .0 11 .8 0. 083 2. 59 2. 50 3371 92. 5 1 .0 2. 59 2. 50 3 627 99.5 ... 48 4. 2 20 . 0–3 .0 181 53 ⁄ 929 0. 22 6 ⁄ 0. 27 7 0. 22 6 75 54 ⁄ 23 ⁄ – 0. 009 1.5 73 ⁄ 81 ⁄ 60 ⁄ – 3 .4 a All crystals belong to space group P 21 21 21 [ 40 , 41 ]; bRmerge ¼ S| I – < I > | ⁄ S < I > ; cR factor...

11
455
0

Davis’s Comprehensive Laboratory and Diagnostic Test Handbook—with Nursing Implications potx

Ngày tải lên : 22/03/2014, 22:20

... 0 115 0 3–35 1 46 12 55 0 5 0 3 0 3 16 84 5 45 5 82 0 4 0 7 0 153 Glutamine Glycine Histidine Homocystine 107 27 6 2 48 8 50 2 98 6 02 72 1 34 3– 20 62 6 20 10 133 5–1 50 10 131 376– 709 24 6 –1 1 82 2 54 82 3 20 5 –756 ... Premature Newborn– mo mo 2 y 2 18 y Adult 0 7 0 80 0–91 23 85 26 –91 151 2 20 48 1 60 1 28 25 5 92 325 0 7 0 2 0 63 3 45 0 53 31 86 22 – 107 30 1 08 47 –155 49 21 6 72 20 1 52 196 48 2 84 116 29 6 Age Methionine ... 147 4 20 55– 147 99 2 20 86 –1 90 15– 143 10 1 70 54 2 10 24 1 74 35 22 6 60 22 5 23 –71 0 79 10 1 40 22 – 1 08 24 115 34 1 12 64 2 94 74 321 119–336 DESCRIPTION: Screening for inborn • Diabetes errors of amino acid...

1.2K
1.5K
0

Báo cáo khoa học: LRRK2 in Parkinson’s disease: function in cells and neurodegeneration doc

Ngày tải lên : 23/03/2014, 04:20

... Journal 27 6 ( 20 0 9) 643 6– 644 4 Journal compilation ª 20 0 9 FEBS No claim to original US government works 644 3 Function in cells and neurodegeneration 39 40 41 42 43 44 45 46 47 48 gene LRRK2 regulates ... Parkinson s disease Antioxid Redox Signal 11, 21 67 2 187 Kumari U & Tan EK ( 20 0 9) LRRK2 in Parkinson s disease: genetic and clinical studies from patients FEBS J 27 6, doi: 10. 1111/j.1 7 42 -46 58. 20 0 9 .07 344 .x ... Shi Y ( 20 0 8) FLIP and the death effector domain family Oncogene 27 , 621 6– 622 7 50 Shi Y ( 20 0 2) Apoptosome: the cellular engine for the activation of caspase-9 Structure 10, 28 5 – 28 8 51 Scafﬁdi C,...

9
478
0

google sketchup for game design [electronic resource] beginner's guide create 3d game worlds complete with textures, levels, and props

Ngày tải lên : 31/05/2014, 00:43

... 116 1 18 119 1 20 1 20 121 122 122 123 1 24 127 1 28 129 1 32 1 32 133 1 34 137 1 40 [ iii ] This material is copyright and is licensed for the sole use by REKHA NADENDLA on 2nd December 20 1 1 375 N STEPHANIE ... level Time for action – creating a web playable walkthrough Time for action – copying and pasting the pallet multiple times Summary 83 83 86 89 92 94 95 98 100 1 02 1 02 103 103 105 107 107 1 10 111 ... Exporting your game for others to play Time for action – who said you can't have your game and play it? Summary Appendix A: MakeHuman 20 7 2 08 2 08 21 5 21 7 2 18 22 3 22 3 22 7 22 9 22 9 23 1 23 3 2 34 23 6...

269
875
1

báo cáo hóa học: " TLR3 signaling is either protective or pathogenic for the development of Theiler''''s virus-induced demyelinating disease depending on the time of viral infection" docx

Ngày tải lên : 19/06/2014, 22:20

... encephalomyelitis virus is mediated by the Toll-like receptor Glia 20 0 6, 53 :85 8 -86 7 26 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 So EY, Kim BS: Theiler 's virus infection induces TLR3-dependent ... backcrossing to SJL/J mice with a low dose (2 x 105 PFU) of TMEV BeAn These virus-infected mice were then assessed for the progression of demyelinating disease for 80 dpi (Fig 2A) We chose the low ... groups was very significant (P < 0. 0 02 6) and the difference between untreated and post -treated groups was significant (P < 0. 0 189 ) (B) Viral persistence levels in the brain (BR) and spinal cord (SC)...

42
496
0

Change One Thing Discover What''''s Holding You Back and Fix It With the Secrets of a Top Executive Image Consultant_1 docx

Ngày tải lên : 21/06/2014, 03:20

... a boss who The Clothes Make the Manager 35 was the nephew of the CEO The boss wore his hair down to his shoulders, and his shirts were often unbuttoned and untucked Even though he was my ... This The Clothes Make the Manager 39 might change as corporate dress codes become less formal, but for now, you should invest in some pecan and off-black hose No prints, no fishnets, no seams ... give It is a source of great confusion, made even more difficult by the depth-defying shoes and other fashions set by the hit TV show Sex and the City Here s the scoop for today s stylish women...

23
436
0

Change One Thing Discover What''''s Holding You Back and Fix It With the Secrets of a Top Executive Image Consultant_2 pptx

Ngày tải lên : 21/06/2014, 03:20

... certain standards for weight, cholesterol, and blood pressure Obese women fare a bit worse than their male counterparts, according to a 20 0 7 study of more than 2, 80 0 Americans In that study, more ... drop-waist styles The combination of a V-necked blouse and A-line skirt is especially good for a woman with this body type If your arms are slender, show them off with sleeveless tunics and above -the- knee ... before the waist begins Lower-rise pants elongate the waist For an even longer silhouette, wear boot-cut pants with shoes or boots that have a slight heel Pears should also choose A-line skirts,...

23
423
0