targets for ambient no2 and pm10 concentrations
Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx
Ngày tải lên :
14/02/2014, 22:20
... focus on the roles of ANGPTL2 and ANGPTL6 ⁄ AGF in obesity and related metabolic diseases, and discuss whether these ANGPTLs could be targets for the prevention and treatment of these conditions ... receptors and promotes monocyte chemotaxis through a4 and b2 integrin receptors [15] Angiopoietin signaling is regulated by two independent receptors; Tie2 receptor and integrins [22] Therefore, ... ANGPTL2 and ANGPTL6 ⁄ AGF in obesity and related metabolic diseases The expression of ANGPTL2 and ANGPTL6 ⁄ AGF is induced in obese conditions ANGPTL2 induces chronic adipose tissue inflammation and...
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Báo cáo khoa học: K4, K9 and K18 in human histone H3 are targets for biotinylation by biotinidase pdf
Ngày tải lên :
23/03/2014, 15:20
... biotinidase, and that K4 and K9 may also be targets for biotinylation in vivo All subsequent enzymatic biotinylations were conducted for 45 The next series of experiments focused on K4, K9 and K14 ... K9 and K18 Discussion This study provides evidence (a) that K4, K9 and K18 in histone H3 are good targets for biotinylation by human biotinidase; (b) that K14 and K23 are relatively poor targets ... Zealand rabbits, following NIH and USDA guidelines for animal care All possible measures were taken to minimize pain and discomfort to animals Booster injections were given after 14, 21 and 49...
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Báo cáo khoa học: Structure of the substrate complex of thymidine kinase from Ureaplasma urealyticum and investigations of possible drug targets for the enzyme pdf
Ngày tải lên :
30/03/2014, 11:20
... selected nucleoside analogues with Uu-TK and hTK1 Substrate concentrations were lM dT and mM ATP for Uu-TK and 0.2 lM dT and mM ATP for hTK1 IC50 (lM) Substrate Uu-TK dU FdU MeT EtdU FIAU FLT ... deoxyribonucleoside kinases and form a separate structural family Humans carry four deoxyribonucleoside kinases: cytosolic TK1 and deoxycytidine kinase, and mitochondrial TK2 and deoxyguanosine kinase ... from the Swedish Research Council for the Environment, Agricultural Sciences and Spatial Planning (to L.Y and S.E.), the Swedish Research Council (to H.E and S.E.), and the Swedish Cancer Foundation...
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Báo cáo sinh học: " Divergence of the mRNA targets for the Ssb proteins of bacteriophages T4 and RB69" ppt
Ngày tải lên :
18/06/2014, 22:20
... (Panels A and B) and T4 gp32 (Panels C and D) Figure In vitro footprinting of RB69 gene 32-specific RNA with purified RB69 gp32 (Panels A and B) and T4 gp32 (Panels C and D) Preparation of RNA and ... extended the information we obtained from treatments with DMS and DEPC about intrinsic structure of the RNA targets Results are shown in Fig for the RB69-derived RNA target and Fig for the T4-derived ... operator RNA as a ligand for T4 gp32 and that RNA of nonspecific sequence is the least preferred nucleic-acid ligand for this Ssb protein [10-12] In vivo, T4 encoded mRNA for gp32 is intrinsically...
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báo cáo hóa học:" Divergence of the mRNA targets for the Ssb proteins of bacteriophages T4 and RB69" doc
Ngày tải lên :
20/06/2014, 04:20
... (Panels A and B) and T4 gp32 (Panels C and D) Figure In vitro footprinting of RB69 gene 32-specific RNA with purified RB69 gp32 (Panels A and B) and T4 gp32 (Panels C and D) Preparation of RNA and ... extended the information we obtained from treatments with DMS and DEPC about intrinsic structure of the RNA targets Results are shown in Fig for the RB69-derived RNA target and Fig for the T4-derived ... operator RNA as a ligand for T4 gp32 and that RNA of nonspecific sequence is the least preferred nucleic-acid ligand for this Ssb protein [10-12] In vivo, T4 encoded mRNA for gp32 is intrinsically...
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Báo cáo hóa học: " Research Article Sequential Monte Carlo Methods for Joint Detection and Tracking of Multiaspect Targets in Infrared Radar Images" pptx
Ngày tải lên :
22/06/2014, 19:20
... coefficients, respectively, for targets and The outputs of the two matched filters minus the corresponding energy terms for targets and 2, respectively, are finally added together and thresholded to provide ... other hand constant with sn for most possible locations of targets i and j on the image grid, except when either one of the two targets or both are close to the image borders Finally, for i = ... al for target aspect and motion and review the observation and clutter models focusing on the GMRf representation of the background and the derivation of the associated likelihood function for...
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Báo cáo y học: "Bacterial and human peptidylarginine deiminases: targets for inhibiting the autoimmune response in rheumatoid arthritis" ppt
Ngày tải lên :
12/08/2014, 12:20
... between human and bacterial species Etiological association between periodontitis and rheumatoid arthritis The rationale for considering both human and P gingivalis PADs in the etiology and pathology ... arthritis and periodontitis Int Immunopharmacol 2009, 9:38-42 Moen K, Brun JG, Madland TM, Tynning T, Jonsson R: Immunoglobulin G and A antibody responses to Bacteroides forsythus and Prevotella ... denticola, and Tannerella forsythia are some of the major Gram-negative bacteria that exist as part of a complex bacterial biofilm in the gingival crevice and are linked to the development and progression...
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Báo cáo y học: " N-α-PGP and PGP, potential biomarkers and therapeutic targets for COPD" pptx
Ngày tải lên :
12/08/2014, 14:20
... isopropanol/0.1% formic acid Positive electrospray mass transitions were at 270-70 and 270-116 for PGP and 312-140 and 312-112 for N-α-PGP The R2 value for the calibration curves for PGP was 0.988 and the ... analysis and drafted the manuscript; PLJ performed the mass spectrometric analyses and collagen digestion assays; BN performed the animal studies; SP and MD provided the sputum and serum samples and ... idea that N-α-PGP and PGP are novel biomarkers and therapeutic targets for COPD Necessary future directions include measuring N-α-PGP and PGP in a larger cohort of COPD patients and controls, correlating...
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Báo cáo y học: "The ADAMs family of proteases: new biomarkers and therapeutic targets for cancer" pptx
Ngày tải lên :
13/08/2014, 13:20
... Therapeutics for Cancer Ireland for funding this work Author details Department of Pathology and Laboratory Medicine, St Vincent’s University Hospital, Dublin 4, Ireland 2UCD School of Medicine and Medical ... (primarily ADAM10 and ADAM17) are involved in proteolytic ectodomain shedding of membrane bound ligands The released ligands (for example, EGF, HB-EGF, TGFa, heregulins) are free to bind to and activate ... Hospital, Dublin 4, Ireland Authors’ contributions MJD researched the literature, conceived and wrote the manuscript PMcG designed and formatted Figure All authors read, edited and agreed with the...
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Towards identifying novel modulators and targets for alzheimers disease therapy
Ngày tải lên :
09/09/2015, 11:27
... out to understand the involvement of GSK-3 and its isoforms, α and β, in oxidative stress, neuronal cell loss, inflammation, NFT and Aβ formation in AD GSK-3β’s link to plaque and tangle pathology ... culminating in both the sporadic and familial forms of AD [37-40] The two isoforms of GSK-3, GSK-3α and GSK-3β, are important for normal development, neuronal growth and differentiation, metabolic ... progression and diagnosis and for identifying disease biomarkers for 13 differentiating clinically developed AD from healthy controls [86-89] Although this platform can be used to understand drug...
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POLICY CREDIT MANAGEMENT IN VIETNAM BANK FOR SOCIAL POLICIES TO MEET TARGETS OF POVERTY REDUCTION AND ENSURING SOCIAL SECURITY
Ngày tải lên :
05/05/2016, 15:34
... symposiums; Analyze and synthesize data and forecasts New contribution of the research Theory: The thesis has codified and systematically analyzed forms of policy credit and contents, methods ... under good control and the secured and stable operation of VBSP is enabled, in contribution to cut down the operation cost such as cost for loans management and non-performing loan handling etc, The ... BANK FOR SOCIAL POLICIES TO MEET TARGETS OF POVERTY REDUCTION AND ENSURING SOCIAL SECURITY 3.1 TARGETS OF POVERTY REDUCTION AND SOCIAL SECURITY BY 2020 3.1.1 Target of poverty reduction and social...
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Check Your English Vocabulary for Phrasal Verbs and Idioms.pdf
Ngày tải lên :
08/08/2012, 17:32
... in this exercise are informal or very informal Idioms and other expressions for describing character and personality The words and expressions in the box can all be used informally to describe ... 65 66 – 80 Idioms and other expressions using animals Idioms and other expressions for describing character and personality Idioms and other expressions using clothes Idioms and other expressions ... verb Most phrasal verbs are formed from a small number of verbs (for example, get, go, come, put and set) and a small number of particles (for example, away, out, off, up and in) Phrasal verbs sometimes...
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Longman-Grammar and Vocabulary for Cambridge Advanced and Proficiency (2)
Ngày tải lên :
05/10/2012, 09:51
... It looks, for example, at verb and noun structures, adverb and adjective structures, and ways of linking complex sentences and texts It also provides information on style and register, for example ... William, Sally and Claire for their untold patience John Eckersley for his generosity and support Clive, Judith and the staff and students at BEET Language Centre, Bournemouth The staff and students ... things for people like her who (1 3) going to Glastonbury for the first time She suspected the forrner would be ' (1 4) like rnad for rniddle-aged has-beens' and ignore up -and- corning...
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Longman-Grammar and Vocabulary for Cambridge Advanced and Proficiency
Ngày tải lên :
05/10/2012, 09:51
... It looks, for example, at verb and noun structures, adverb and adjective structures, and ways of linking complex sentences and texts It also provides information on style and register, for example ... William, Sally and Claire for their untold patience John Eckersley for his generosity and support Clive, Judith and the staff and students at BEET Language Centre, Bournemouth The staff and students ... things for people like her who (1 3) going to Glastonbury for the first time She suspected the forrner would be ' (1 4) like rnad for rniddle-aged has-beens' and ignore up -and- corning...
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R Side G Wellman (Longman) Grammar and Vocabulary for Cambridge Advanced and Proficiency
Ngày tải lên :
05/10/2012, 09:58
... It looks, for example, at verb and noun structures, adverb and adjective structures, and ways of linking complex sentences and texts It also provides information on style and register, for example ... William, Sally and Claire for their untold patience John Eckersley for his generosity and support Clive, Judith and the staff and students at BEET Language Centre, Bournemouth The staff and students ... things for people like her who (1 3) going to Glastonbury for the first time She suspected the forrner would be ' (1 4) like rnad for rniddle-aged has-beens' and ignore up -and- corning...
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Báo cáo y học: "Oral Rehydration Therapy for Preoperative Fluid and Electrolyte Management"
Ngày tải lên :
25/10/2012, 10:51
... sodium, and urinary creatinine Vital signs were analyzed using the repeated-measures analysis of variance and the Dunnett test (two-sided at =0.05) Blood and urine values and FENa values before and ... timing and volume of consumption and the taste and temperature of the fluid should be further improved so that all patients can pleasantly drink for fluid and electrolyte replenishment before surgery ... electrolytes, and carbohydrates [8, 9] We conclude that ORT is a safe and effective therapy for the preoperative fluid and electrolyte management of selected surgical patients Table Eligibility standard for...
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Smart Thinking_Skills for Critical Understanding and Writing, 2nd Ed
Ngày tải lên :
08/11/2012, 10:46
... SMART THINKING For Jane and Verity (as ever) SMART THINKING SKILLS FOR CRITICAL UNDERSTANDING AND WRITING Second Edition MATTHEW ALLEN OXFORD UNIVERSITY P R E S S OXFORD UNIVERSITY PRESS ... of information, then you will be able to find, shape, and use knowledge for yourself But reasoning is also about people: the authors and audiences of arguments, explanations, and so on And it ... analysis 103 Information understood by where we find it 106 Information as it relates to other information 108 Information classified by the topic under investigation 100 109 Information as it...
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A Study of Channel Estimation for OFDM Systems and System Capacity for MIMO-OFDM Systems
Ngày tải lên :
20/11/2012, 11:28
... The waveform of Gk ( w) The transmitted signals for the k1-th subcarrier and k2-th subcarrier in frequency domain are therefore X i ,k1 Gk1 ( w) and X i ,k2 Gk2 ( w) , respectively, and satisfy ... estimation for the first M1 OFDM symbols, for f d T = 0.01, 0.06 and 0.1, respectively 114 Fig 4.3: The NMSE of channel estimation based on equi-spaced and grouped pilot pattern, viii for the ... T = 0.01 and 0.1, respectively 116 Fig 4.6: The NMSE of channel estimation for the proposed algorithm and LS algorithm by numerical method and simulation at f d T = 0.01 and 0.06,...
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