tams and th17 cells in the tumor microenvironments
Pulmonary tuberculosis associated with increased number and percentage of natural killer and B cells in the peripheral blood pot
Ngày tải lên :
29/03/2014, 03:20
... detected in patients with PTB in this study may therefore indicate the contribution of NK cells in the host immune response against MTB infection The immune response after MTB infection and disease ... the patients in this study Immunity against MTB comprises of a predominant cellular response and majority of researchers have dismissed the participation of B cells in defending against the infection ... response against MTB by increasing the infection inoculum (Vordermeier et al., 1996; Maglione et al., 2007) In addition the protection of mice against MTB infection by administration of intravenous...
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Báo cáo khoa học: "Comparative study of endocrine cells in the principal pancreatic islets of two teleosts, Silurus asotus (Siluridae) and Siniperca scherzeri (Centropomidae)" potx
Ngày tải lên :
07/08/2014, 14:23
... study of the endocrine cells within the pancreas, intestine, and stomach of the gar Gen Comp Endocrinol 1997, 106, 1-16 Guyot, E., Diaz, J P., Romestand, B and Connes, R Insulin during the early ... PP-immunoreactive cells Insulin is synthesized in the B cells of the pancreatic islets and regulates the serum glucose levels (Hsu and Crump, 1989) The regional distribution and relative frequency of the insulin-immunoreactive ... chromogranin containing cells in the porcine gastroenteropancreatic endocrine system Jpn J Vet Sci 1987, 50, 395-404 11 Jansson, L and Sandler, S L The influence of cyclosporin A on the vascular...
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Báo cáo khoa học: " An immunohistochemical study of chromogranin A and Sp-1 immunoreactive cells in the gastrointestinal tract of ovariectomized rats" pdf
Ngày tải lên :
07/08/2014, 18:21
... lanoitubirtsid eht ,hguohtlA ]8,3[ sllec enircodneoruen lla fo ”srekram“ nommoc yltnacifingis a ,stneitap aitreni cinoloc nI slamina fo sutats evitsegid ot detaler ylraelc erew sllec RI-GC fo segnahc eht ... enircodne ni A ninargomorhc fo noitartsnomed lacimehcotsihonummI T aganawI ,N arahianaY ,F otaS ,H ikhO ,Y otomihsaH 01 892-782 ,25 ,9891 lotyC lotsiH hcrA saercnap enircodne eninac eht ni II ninargoterces ... yltnacifingis a ,noitidda nI ]5[ esaesid s’nhorC dna ]5[ sitiloc evitareclu ,]41[ romut ,]61[ noitapitsnoc cinorhc htiw stneitap fo mutcer eht ni desaercni osla yeht dna ]43[ asocum cinoloc ni...
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Báo cáo khoa học: "Changes of gastrointestinal argyrophil endocrine cells in the COLO205 tumor-implanted Balb/c-nu/nu mice" pps
Ngày tải lên :
07/08/2014, 18:21
... enircodne cinoloC L suilemirG ,R gnilnetS ,A nossleinaD ,M yhlaS-lE 943-143 ,772 ,4991 seR eussiT lleC ,gorf neerg eht fo tcart yratnemila eht fo sllec enircodne eht ni B dna A ninargomorhc ... nI stluseR 962 giF ecnereffid tnacifingis a deredisnoc saw 50.0 naht ssel fo eulav-p a dna )ASU ,SSPS ;3.1.6 esaeleR( swodniW rof SSPS htiw atad fo ecnacifingis eht ezylana ot desu saw )tset ... dezimotceiravo eht ni detroper erew sllec lihporygra IG fo esaerced yltnacifingis a ,noitidda nI ]62[ aimena suoicinrep dna ,]3[ aimenirtsagrepyh ,]1[ sitirtsag cihporta ,]7[ esaesid s’nhorC...
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Báo cáo khoa học: "Autologous somatic cell nuclear transfer in pigs using recipient oocytes and donor cells from the same animal" pdf
Ngày tải lên :
07/08/2014, 20:23
... viability in vitro and in vivo [4,12,39], but there are few reports on autologous SCNT in pigs The objective of the present study was to examine the feasibility of producing autologous porcine SCNT ... cell cycle is an important factor in the development of SCNT embryos [6,38] Cells in the G0/G1 phases are superior to cells in other phases of the cycle in terms of their ability to support NT embryo ... different since the CCCs were cultured for only 18 h and were probably in the actively growing phase However, this probable difference in the cell cycle was not reflected in the development of the SCNT...
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Báo cáo y học: "Synergistic role of c-Myc and ERK1/2 in the mitogenic response to TGF-1 in cultured rat nucleus pulposus cells" ppsx
Ngày tải lên :
09/08/2014, 01:22
... proliferation and the cell cycle progression in nucleus pulposus cells, (2) determine if c-Myc transcription inhibitor obstructed the effect of TGF1, and (3) determine the role of ERK1/2 in stabilizing the ... treatment The cell cycle distribution in TGF1treated cells (Figure 5b) indicates a large increase in cells in the S phase, associated with the suppression of p21 and p27 which belong to the Cip/Kip ... Competing interests The authors declare that they have no competing interests 14 Authors' contributions TN and DS conceived of the study and performed the experimental work DS and JM participate in...
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Báo cáo y học: "Regulating the immune system: the induction of regulatory T cells in the periphery Jane H Buckner1 and Steven F Ziegler2" pot
Ngày tải lên :
09/08/2014, 01:24
... when the body is threatened by infection or injury In this setting T cells will become activated, and will recruit other T cells and other inflammatory cells and mediators to the site As the response ... fate of the TR cells induced at the site is not known — whether these cells exist only transiently then die, whether they persist in the body as TR cells, or whether they return to their previous ... involution, and antigen exposures, the development of CD4+CD25+ TR cells may occur in the periphery in man Induction of CD4+CD25+ TR cells in the periphery The induction of TR cells that resemble the...
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Báo cáo y học: "Interleukin-15 and interferon-γ participate in the cross-talk between natural killer and monocytic cells required for tumour necrosis factor production" docx
Ngày tải lên :
09/08/2014, 08:22
... supporting the importance of intercellular contacts in the pathogenic mechanisms underlying RA Indeed, the importance of these cell-cell interactions in the synthesis and release of pro-inflammatory ... CD48, than in monocytes that express both CD48 and CD244 Thus, our findings show that NK cells can engage and stimulate monocytic cells, resulting in the synthesis of TNF This finding opens the possibility ... PR-N obtained purified NK cells EF-R and DS participated in the design of the study and helped to draft the manuscript FS-M participated in the design of the study and its coordination and helped...
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Báo cáo y học: " The inflammatory response seen when human omental adipose tissue explants are incubated in primary culture is not dependent upon albumin and is primarily in the nonfat cells" pps
Ngày tải lên :
11/08/2014, 08:22
... cells Interestingly over the 48 h incubation there was a marked increase in 11b HSD-1 gene expression in nonfat but not in fat cells [Figure 4] The increases in IL-8 release and mRNA in non-fat cells ... 48 h was examined in the studies shown in figure There were significant additional increases in the mRNAs for IL-8, HIF1a, and 11b HSD1 in the nonfat cells over the 48 h incubation There was also ... studies and analysis of mRNA DT and AM selected the donors, obtained the samples of fat and aided in the interpretation of the data All authors read and approved the final manuscript Competing interests...
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Báo cáo y học: "Dendritic cells: In the forefront of immunopathogenesis and vaccine development – A review." doc
Ngày tải lên :
11/08/2014, 10:23
... colonize the gut and express and release the immunogen in the intestine DCs in the mucosal site will then capture the immunogen via DC-binding peptide motifs They internalize the immunogen, process and ... antigen-specific B cells [29] T- and B-cell interaction results in the clonal expansion of B cells, which takes place in the plasma foci of the T cell rich area [30] and in the germinal centers [31] T- and ... Based Therapies and Vaccines 2004, Origin and developmental processes of dendritic cells DCs originate from hematopoietic stem cells in the bone marrow Recently, there have been great insights into...
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Báo cáo y học: " Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus" doc
Ngày tải lên :
12/08/2014, 12:20
... IL-17 producing T cells, including CD4 + and DN T cells, have been found in lupus nephritis In addition, IL17 gene expression was detected in T cells infiltrating the kidneys and in urine sediments ... activating factor (BAFF) in promoting the survival and proliferation of human B cells and their differentiation into antibody-producing cells [25] Yet, it remains unknown why IL-17 production is increased ... of Th17 and Th1 responses We investigated whether the frequency of Th17 and Th1 cells in patients with SLE differed from that in healthy individuals After stimulating PBMCs for hours with PMA and...
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Báo cáo y học: " CD39+ Regulatory T cells suppress generation and differentiation of Th17 cells in human malignant pleural effusion via a LAP-dependent mechanism" pps
Ngày tải lên :
12/08/2014, 13:22
... and differentiation and of Th17 cells; in contrast, TGF-b could reduce the increased percentage of Th17 cells stimulated by the above cytokines On the other hand, TGF-b was capable of promoting ... affect the generation and differentiation of Tregs or /and Th17 cells in MPE To evaluate the contribution of cytokines to the numbers of pleural CD39+Tregs and Th17 cells, we purified naïve CD4+ T cells ... possessing typical phenotypes of Tregs Impacts of Cytokines on Tregs and Th17 Cells in MPE We determined some cytokines that reported be involved in generation and differentiation of Tregs or Th17 cells, ...
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Báo cáo y học: "Alterations of alveolar type II cells and intraalveolar surfactant after bronchoalveolar lavage and perfluorocarbon ventilation. An electron microscopical and stereological study in the rat lung" pdf
Ngày tải lên :
12/08/2014, 15:20
... obtained at baseline, thereafter treatment according to randomization was initiated In the Lavaged-Gas group conventional mechanical ventilation was continued with the same ventilatory setting In ... between the T piece of the ventilator and the endotracheal tube Measurements were performed prior to lavage, at baseline and 30 and 60 minutes of therapy Fixation, sampling and processing All ... from collapsing during the fixation procedure The abdominal cavity was opened and animals were exsanguinated After opening the thoracic cavity, the pulmonary artery was canulated and the lung was...
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Báo cáo y học: "Sequestration and homing of bone marrow-derived lineage negative progenitor cells in the lung during pneumococcal pneumonia" ppsx
Ngày tải lên :
12/08/2014, 15:21
... these Lin- PCs migrated into the airspaces (approximately 3.1% of all the cells remaining in the lung), therefore approximately 14.6% of the initially infused Lin- PCs homed to lung tissues and ... regeneration and repair These findings showed firstly that very few progenitor cells migrate into the airspaces to participate in airspace inflammation but the majority of cells remain in the lung ... when cells for resolution and repair are required Alternatively, these cells may remain in the less hostile intravascular milieu to proliferate and mature, to home and migrate into the inflammatory...
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Báo cáo y học: "Morphological characterisation of portal myofibroblasts and hepatic stellate cells in the normal dog liver" pptx
Ngày tải lên :
13/08/2014, 13:20
... staining in the perisinusoidal spaces throughout the parenchyma b) HSC stain positive, producing a thin irregular positive band lining the sinusoids c) HSC stain positive A positive cell containing ... consistently in all slides In the portal areas, the terminal and sublobular hepatic veins, and in Glisson's capsule identical staining was observed In the hepatic parenchyma moderate positive staining ... insight in normal baseline variation In the formalin fixed paraffin embedded normal canine liver vimentin staining did not differentiate between fibroblasts and MF in the portal area and the perivenous...
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Báo cáo y học: "Discovery of estrogen receptor α target genes and response elements in breast tumor cells" ppsx
Ngày tải lên :
14/08/2014, 14:21
... From these observations the number of direct target genes involved in initiating hormone response in breast tumor cells might represent only 0.47% (89/18,912) of the genes in the human genome The ... predicted in either organism; conservation of the 20 bases flanking the 5' and 3' ends (40 bases total) of the predicted EREs; and the distance between the binding-site sequences and the TSS refereed ... Materials and methods section), defined as the most 5' nucleotide of the reference transcript in the NCBI RefSeq database, of candidate genes and queried them for potential ER-binding sites The size and...
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Báo cáo sinh học: "Combined therapy with cyclophosphamide and DNA preparation inhibits the tumor growth in mice" docx
Ngày tải lên :
14/08/2014, 19:22
... transformed into an ascitic form, and maintained in this line LSs are highly sensitive to the apoptosis induced by CP and several other alkylating agents The Krebs-2 tumors were initially Figure ... participated in the design of the study and performed the statistical analysis KEO participated in the design of the study DNS helped in the data interpretation ERC performed the analysis and interpreted ... specific IMO ligand is the first and crucial step in activating the DC's ability to induce a biological anticancer effect; subsequently, the synthesis and secretion of main cytokines and T-lymphocyte...
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The role of CD8 t cells in the differentiation of TNF iNOS producing dendritic cells and TH1 responses
Ngày tải lên :
09/09/2015, 18:58
... resulting in the killing of 39 Chapter 1: Introduction these infected cells Under these circumstances, the dying cells, CD8 T -cells and other APCs such as macrophages and DCs within the inflammatory ... activate naive T cells (Steinman and Cohn, 1974) These cells are now known as the primary instigators of the adaptive immunity as they are vital for detecting, alerting and priming the adaptive immune ... antigen and is followed by a contraction phase, when 90–95% of the effector cells die in the ensuing days and weeks and the remaining 5–10% become long-lived memory cells (Harty and Badovinac,...
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Báo cáo y học: Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects"
Ngày tải lên :
03/11/2012, 11:35
... bone graft in the damaged site and on the other hand, it creates an environment with a rich content of HA, with all the advantages deriving from the phenomenon The present study’s clinic and radiologic ... for the tools and facilitate the direct clinical view of the defect [fig 3-4] A full-thickness flap was elevated and the granulation tissue was removed showing the true extension and depth of the ... suggest that integrin-mediated interaction plays a decisive role in 67 the regulation of proliferation, migration, and differentiation of the epithelial cells [2,12,18,19] Following the surgical...
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