systemic treatment of soft tissue sarcomas
advances in cancer research
... Treatment of Myelomatosis Systemic Treatment of Kaposi's Sarcoma Systemic Treatment of Soft Tissue Sarcomas 119 134 141 146 149 152 vi i CONTENTS VII Systemic Treatment of Osteosarcomas ... Systemic Treatment of Malignant Melanoma IX Systemic Treatment of Renal Cell Carcinoma X Systemic Treatment of Lung Cancer XI Systemic Treatment of Gastric Cancer XI1 Systemic Treatment ... XVI Systemic Treatment of Brain Tumors XVII Systemic Treatment of Neuroblastoma XVIII Systemic Treatment of Prostate Carcinoma XIX Systemic Treatment of Carcinoma of the Uterine...
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Lung cancer - The diagnosis and treatment of lung cancer pdf
... evidence III Studies with level of evidence IV DS, diagnostic studies Levels of evidence for studies of the accuracy of diagnostic tests Levels of evidence Ia Type of evidence • Ib II • • III • ... professionals and patients is essential It should be supported by the provision of evidence-based information, offered in a form that is tailored to the needs of the individual patient The treatment, ... radiotherapy should be offered sequential chemoradiotherapy A 1.8 Treatment of small-cell lung cancer 1.8.1 Patients with SCLC should be offered an assessment that includes evaluation of the major prognostic...
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Báo cáo khoa học: "Comparison of conformal and intensity modulated radiation therapy techniques for treatment of pelvic tumors. Analysis of acute toxicity" pdf
... of the PTV, ranged from 45 to 50.4 Gy, delivered in 25 to 28 daily fractions in the phase of elective pelvic lymph node treatment Treatment plannings were generated using the Eclipse Helios software ... volume of small bowel Int J Radiat Oncol Biol Phys 2009, 74:1476-1480 Page of 12 Sondergaard J, Hoyer M, Petersen JB, et al: The normal tissue sparing obtained with simultaneous treatment of pelvic ... 0.01) (Table 5) Crude incidence of acute GU toxicity was similar in both groups among patients with rectal cancer (Table 6) Discussion Use of IMRT in the treatment of pelvic tumors has been increasing...
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báo cáo khoa học: "Treatment of malignant tumors of the skull base with multi-session radiosurgery" pdf
... extent of contact and compression of critical neurological structures Details of the radiosurgical treatments are found in Table A median treatment dose of 2500 cGy was delivTable 3: Radiosurgery treatment ... fossa Parasellar Orbit Petroclival Goal of CyberKnife treatment Primary treatment for local disease (%) Secondary treatment (%) Previous treatment Previous craniofacial surgery Previous external beam ... responsibility for all aspects of the treatment planning and procedure, determined the minimal tumor margin dose of the target vol- ume, the treatment isodose and the number of treatment sessions into...
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Effective treatment of solid tumors via cryosurgery
... side of the equation is the rate of increase of φ while the second term on the left is the net rate of flow of φ out of fluid element The first term on the right side is the rate of change of φ ... Development of the ice front and the boundary of the complete ablation 77 Figure 5.16 Classification of profiles and equivalent ellipsoid: (a) classification of profile in terms of border ... after thawing [51] The loss of blood supply deprives cells of any possibility of survival with an uniform ablation of tissue, except at the boundary of previously frozen tissue [51] 2.3.3 Critical...
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Báo cáo khoa học: "Surgical strategies for treatment of malignant pancreatic tumors: extended, standard or local surgery?" potx
... of both cephalic and distal pancreatic remnants [1] Moreover, the laparoscopic technique, one of the best examples of modern surgery, is now more widely used for the diagnosis and treatment of ... resected [21] In a systemic review of 1.646 Table 1: Reports of pancreatoduodenectomy (PD) with simultaneous venous vessel resection (VR) Author (Year of publication) Number of PD with VR Mortality ... attempted because of locally unresectable disease [29] In an analysis by Shimada et al of 88 patients with extended DP, which Page of 10 (page number not for citation purposes) World Journal of Surgical...
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Báo cáo khoa học: " Radical stereotactic radiosurgery with real-time tumor motion tracking in the treatment of small peripheral lung tumors" docx
... (range, 0.9 – 3.5 cm) Treatment characteristics Three equal fractions of 15 to 20 Gy were delivered in an average of days (Table 3) Treatment plans were composed of hundreds of pencil beams shaped ... stop smoking just prior to treatment; any deleterious effects of radiosurgery may be offset by the early beneficial effects of smoking cessation [25] Ninety-five percent of the patients in the current ... were imaged prior to the delivery of every third beam for treatment verification and to update the correlation model [16] If fiducials were misidentified by the software or the correlation model...
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báo cáo hóa học:" Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumors" docx
... to improve the effectiveness of systemic chemotherapy The novel strategy that I propose here to improve the effectiveness of systemic chemotherapy in the treatment of malignant brain tumors is ... limit of pore size in the BBTB of the microvasculature of early, less mature and smaller malignant brain tumor colonies is to nanometers lower than that of the BBTB of the microvasculature of late, ... randomized trial of surgery in the treatment of single metastases to the brain New England Journal of Medicine 1990, 322:494 Jellinger K, Volc D, Grisold W: Multimodality treatment of malignant gliomas...
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Báo cáo khoa học: " Neoadjuvant radiochemotherapy in the treatment of fixed and semi-fixed rectal tumors. Analysis of results and prognostic factors" pptx
... subject of controversy One of the most important controversies is whether the degree of downstaging warrants this type of surgery [1] Results of the German (CAO/ARO/AIO 94) randomized trial of preoperative ... actuarial method of Kaplan and Meier [24] The calculation of OS, DFS and LC was performed from the date of diagnosis to the date of the event Survival was measured from the date of diagnosis to ... Results Neadjuvant treatment Of the 101 patients treated, (6.9%) did not complete the prescribed dose of preoperative RT because of persistent neutropenia and/or diarrhea Of these, two died due...
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Báo cáo khoa học: " CyberKnife® radiosurgery in the treatment of complex skull base tumors: analysis of treatment planning parameters" potx
... single measure of how well the treatment dose distribution of a specific radiation treatment plan conforms to the size and shape of the target volume In general, the conformity index of a given radiosurgical ... simultaneous irradiation of multiple lesions The lack of a requirement for the use of a head-frame allows for staged treatment Since the planning system has access to a large number of potential non-isocentric ... critical structures The planning software calculated the optimal solution for treatment The DVH of each plan was evaluated until an acceptable plan was generated Treatment planning parameters Target...
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Báo cáo y học: "Local adherent technique for transplanting mesenchymal stem cells as a potential treatment of cartilage defect" pdf
... Y, Kawasaki K, Wakitani S, Iwasa J: Transplantation of cartilage-like tissue made by tissue engineering in the treatment of cartilage defects of the knee J Bone Joint Surg Br 2002, 84:571-578 Wakitani ... sections of the repaired tissue were analyzed using a grading system consisting of five categories (cell mor- 15 aTotal smooth area of the reparative cartilage compared with the entire area of the ... small portion of the cells adhered to the cartilage defect Injection of more cells would increase the number of cells that adhered to the defect; however, the injection of a large number of cells...
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báo cáo khoa học: "Skeletal Plasmacytoma: Progression of disease and impact of local treatment; an analysis of SEER database" ppt
... cause of death and different treatment groups Our analysis reveals 27 of 60 patients with no attempt at local control, died of myeloma This ratio of progression to myeloma was similar in other treatment ... approximately 26% of the US population It is the only comprehensive source of population based data in the U.S that includes the stage of cancer at the time of diagnosis and follow-up of all patients ... of treatment (occurring within months of diagnosis) [22-34] The SEER program is currently regarded as the standard of quality among cancer registries around the world with case completeness of...
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báo cáo khoa học: "CyberKnife for hilar lung tumors: report of clinical response and toxicity" potx
... from the date of completion of treatment to the last date of follow-up or the date of death Actuarial local control and overall survival were calculated using the Kaplan-Meier method Treatment Delivery ... the response to treatment in solid tumors European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada J Natl ... approaching the limit of 40 Gy A second Unger et al Journal of Hematology & Oncology 2010, 3:39 http://www.jhoonline.org/content/3/1/39 Page of Figure Right hilar metastasis treatment planning PET/CT...
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báo cáo khoa học: "Successful treatment of a T4 lung tumor with vertebral body invasion using fiducial markers in the thoracic spine for image-guided radiation therapy: A case report" pps
... weeks after treatment was completed A CT scan of the chest and abdomen obtained 10 months after radiation treatment showed stable soft- tissue asymmetry in the mediastinum, with no evidence of recurrent ... tight dose fall-off in the area of vertebral body invasion Figure demonstrates the sharp fall-off from the treatment dose of 74 Gy (red) to the approximate spinal cord tolerance dose of 50 Gy (purple) ... accuracy of fiducial markers with the use of other forms of IGRT Watchman et al [10] compared KV X-ray imaging and fiducial marker matching for the set-up of 18 treatment fractions of stereotactic...
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Báo cáo y học: " A novel small molecule target in human airway smooth muscle for potential treatment of obstructive lung diseases: a staged highthroughput biophysical screening" pps
... Function efficacy of small molecules on stiffness of ASM at the level of a single living cell Figure S2: Modulation of pCofilin-14-3-3 protein interactions A potential mechanism of action of small molecules ... Phosphorylated cofilin is bound to 14-3-3 proteins [20-22] and, in human ASM, PKA-activated phosphorylation of HSP20 is associated with dephosphorylation of cofilin and subsequent loss of actin stress ... analogs of HSP20 (pHSP20) co-precipitate with a class of 143-3 proteins and, moreover, competitively inhibit the binding of phosphorylated cofilin to 14-3-3 proteins Using SPR-based evaluation of...
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Báo cáo y học: "Nebulised heparin: a new approach to the treatment of acute lung injury" pdf
... control of physiological variables as well as therapeutic modalities is of the outmost importance [9] The use of treatment bundles’ could be a further necessary step in the direction of optimal ... phases of ALI, how can it be assessed in order to initiate heparin administration as rapidly as necessary? How can dosage of the drug be titrated to achieve maximal local effects without the risk of ... achieve maximal local effects without the risk of systemic complications? What is the adequate duration of this therapy? Does the underlying cause of ALI make any difference with regard to this...
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Cambridge.University.Press.Fearing.Others.The.Nature.and.Treatment.of.Social.Phobia.Mar.2007.pdf
... I is Professor of Clinical Psychology in the Department of Psychology at the University of Montreal Fearing Others The Nature and Treatment of Social Phobia Ariel Stravynski University of Montreal ... disruptive social anxiety are features of the lives of many thousands of people But exactly what is social phobia? What causes it? What is its nature and what kinds of treatments can improve it? Using ... and ways of testing them 81 5.3 Reliability: agreeing about the entity of social phobia 86 5.4 Predictors of response to treatment 95 5.5 Social phobia in the family 99 5.6 Association of social...
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Báo cáo y học: "Clinical review: Treatment of new-onset atrial fibrillation in medical intensive care patients – a clinical framework"
... avoiding Page of 10 (page number not for citation purposes) proarrhythmic drugs Reduction of the systemic inflammatory state is tempting but is of course always the purpose of ICU treatment The ... by insufficient treatment of AF or, on the contrary, is caused by adverse effects of the treatment, however, is too realistic to be ignored All we have stated about the treatment of AF in MICU ... disease and other nosocomial complications Can treatment of atrial fibrillation improve survival? There are few data on the effect of treatment of AF on mortality in ICU patients A meta-analysis...
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Báo cáo y học: "Special considerations in the treatment of patients with bipolar disorder and medical co-morbidities"
... Antipsychotics [29] Initiation of Treatment First Year of Treatment Duration of Treatment • Baseline fasting glucose level • Fasting glucose level every 3–4 months • Observe for signs of hyperglycemia • ... of our patients develop renal disease, psychiatrists must be aware of the effects of psychotropics on the kidneys, as well the effects of decreased renal functioning on the pharmacokinetics of ... bioavailability of free, active highly protein-bound drugs Accumulation of active hydroxylated metabolites of carbamazepine may lead to symptoms of drug toxicity despite therapeutic drug levels [70] Of all...
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Báo cáo y học: "Surgical Treatment of Depressed Scar: A Simple Technique"
... Thus, in these cases especially when there is not a lack of tissue secondary to trauma as for example the suffering of sub-cutaneous adipose tissue, it would be sufficient to eliminate the single ... mind, in the presence of adherent scars, after having infiltrated the whole area with a solution of Lidocaine 0.5% and Epinephrine 1:200,000 very close to one of the two edges of the scar, a small ... the mobility of the recuperated tissue 378 Fig.2: A small incision with an undermining scissor inside it Fig.3: The scar is completely undermined Fig.1: An example of a depressed scar of the abdomen...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể điều tra đối với đối tượng giảng viên và đối tượng quản lí điều tra với đối tượng sinh viên học tiếng nhật không chuyên ngữ1 khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25