... Increased T-lymphocyte apoptosis/necrosis and IL-10 producing cells in patients and their spouses in Icelandic systemiclupuserythematosus multicase families Lupus 2002, 11:435-442 Herrmann M, Voll ... GC: Abnormal T cell signal transduction in systemiclupuserythematosus Arthritis Rheum 2002, 46:1139-1154 Walport MJ: Complement andsystemiclupuserythematosus Arthritis Res 2002, (Suppl):S279-S293 ... Isenberg DA: Cytokines andsystemiclupuserythematosus Ann Rheum Dis 2000, 59:243251 Ytterberg SR, Schnitzer TJ: Serum interferon levels in patients with systemiclupuserythematosus Arthritis...
... of systemiclupuserythematosus Arthritis Rheum 1982, 25:1271-1277 Petri M, Magder L: Classification criteria for systemiclupus erythematosus: a review Lupus 2004, 13:829-837 Rekvig OP, Andreassen ... of systemiclupuserythematosus N Engl J Med 2003, 349:1526-1533 18 Isenberg DA, Ravirajan CT, Rahman A, Kalsi J: The role of antibodies to DNA in systemiclupuserythematosus – a review and ... Andreassen K, Moens U: Antibodies to DNA – towards an understanding of their origin and pathophysiological impact in systemiclupuserythematosus Scand J Rheumatol 1998, 27:1-6 Kaliyaperumal A, Mohan...
... lanes Ki and rP/Ki/his) and U1snRNP-A (U1-A, lanes nRNP and Ku/nRNP), RPA70 co-migrates with Ku p70 (lanes Ku/nRNP and Ku), and RPA14 co-migrates with histone H4 (lanes rP/Ki/his, Histones, and BM6.5) ... components of RPA; of the remainder, one reacted with RPA70 and RPA32, one reacted with RPA14 only, and one was negTable Systemiclupuserythematosus criteria of cases with anti-RPA Criterion Case ... Reeves WH, Narain S, Satoh M: Autoantibodies in systemiclupuserythematosus In Arthritis and Allied Conditions 15th edition Edited by: Koopman WJ, Moreland LW Philadelphia: Lippincott Williams &...
... SLEDAI, SystemicLupusErythematosus Disease activity index; SLICC, SystemicLupus International Collaborating Clinics/American College of Rheumatology Damage Index for systemiclupuserythematosus ... pre-selected systemiclupuserythematosus group with and without Box plot of the optical density (OD) of α-actinin binding in patients from pre-selected systemiclupuserythematosus group with and without ... Rekvig OP, Andreassen K, Moens U: Antibodies to DNA– towards an understanding of their origin and pathophysiological impact in systemiclupuserythematosus Scand J Rheumatol 1998, 27:1-6 Hernando M,...
... organs [6] and is inducible by cells of myeloid origin (monocytes, macrophages, neutrophils, and dendritic cells) and also by osteoclasts (reviewed by Ng and colleagues [3] and Dillon and colleagues ... cytokine levels and B-cell frequency (a) Two patients with systemiclupuserythematosus (SLE) (S5 and S14) representing the frequency relation of B-cell frequency (left y-axis in diagrams) and cytokine ... design, acquired, analysed and interpreted data, prepared the manuscript, and performed statistical analysis MH and IG selected and collected samples and interpreted and provided clinical data...
... enhanced in patients with systemiclupuserythematosusand is associated with arterial and renal disease manifestations Arthritis Rheum 2005, 52:192-200 Wu R, Nityanand S, Berglund L, Lithell ... Hayem G, Nicaise-Roland P, Palazzo E, de Bandt M, Tuback F, Weber M, Meyer OI: Anti-oxidized low-density lipoprotein (OxLDL) antibodies in systemiclupuserythematosus with and without antiphospholipid ... lipoproteins (HDLs) isolated from healthy controls (left column) and patients with systemiclupuserythematosus (SLE) (middle column) and rheumatoid arthritis (RA) (right column) Numbers below 1.0...
... various diseases, such as rheumatoid arthritis (RA), systemiclupuserythematosus (SLE), vasculitis and antiphospholipid syndrome (APLS) Similar to RA and SLE, primary Sjögren's syndrome (pSS) is an ... PS-positive or total), leukocyte and platelet circulating MPs in pSS and other AIDs (SLE and RA) as a biomarker of cell activation Materials and methods Materials and controls The characteristics ... Sjogren's syndrome; RA = rheumatoid arthritis; SLE = systemiclupus erythematosus; SLEDAI = SLE disease activity score (sPLA2) activity and sCD40L and soluble P-selectin (sCD62P) content MP quantification...
... proliferation-inducing ligand; BAFF, B-cell activation factor of the TNF family; BLyS, B-lymphocyte stimulator; SLE, systemiclupus erythematosus; TACI, transmembrane activator and CAML interactor; ... WJ, Fernandez V, Chevrier MR, Zhong ZJ, Freimuth WW: A phase II, randomized, double-blind, placebo-controlled, dose-ranging study of belimumab in patients with active systemiclupuserythematosus ... bone marrow and poorly expressed by early-life bone marrow stromal cells Blood 2008, 111:2755-2764 doi:10.1186/ar2976 Cite this article as: Stohl W: Systemiclupuserythematosusand its ABCs...
... germinal centre (GC) A and GC B, and B-cell clusters C and D were derived Groups of sequences were deemed to be clonally related when they used the same V, D, J and CDR3, and differed only by base ... from each of the systemiclupuserythematosus splenic germinal centres and Bcell clusters GC A GC B (a) Location GC/cluster Total VH Segment Framework VH5-51 VH2-5*02 10 CDR1 and CDR2 a b a A ... subjects and patients with systemiclupuserythematosus Int Arch Allergy Immunol 2000, 123:36-45 27 de Wildt RMT, Tomlinson IM, van Venrooij WJ, Winter Ga, Hoet RMA: Comparable heavy and light...
... erythematosus patients systemic TNF stimulation on gene expression in healthy individuals Effect of TNF stimulation on gene expression in healthy individuals andandsystemiclupuserythematosus patients ... mononuclear cells (PBMCs) from six systemiclupuserythematosus (SLE) patients and three healthy individuals (HI) were isolated and stimulated for 24 hours in the absence and presence of 20 ng/ml TNF ... interleukin-12 and other Th1-type cytokines in patients with recent-onset systemiclupuserythematosus Arthritis Rheum 1998, 41:838-844 Liu TF, Jones BM: Impaired production of IL-12 in system lupus erythematosus...
... Prevalence and risk factors of carotid plaque in women with systemiclupuserythematosus Arthritis Rheum 1999, 42:51-60 Salmon JE, Roman MJ: Accelerated atherosclerosis in systemiclupus erythematosus: ... asymptomatic patients with systemiclupuserythematosus Am J Med 1984, 77:286-292 Shome GP, Sakauchi M, Yamane K, Takemura H, Kashiwagi H: Ischemic heart disease in systemiclupuserythematosus A retrospective ... cardiovascular risk factors in systemiclupuserythematosus J Musculoskel Med 1998, 15: 42-52 El-Magadmi M, Ahmad Y, Wajed J, Bruce IN: The bimodal mortality pattern in systemiclupuserythematosus Curr...
... classification of systemiclupuserythematosus [letter] [see comments] Arthritis Rheum 1997, 40:1725 32 Trysberg E, Nylén K, Rosengren LE, Tarkowski A: Neuronal and astrocytic damage in systemiclupuserythematosus ... M, Hardin JG, Michalski JP: Systemiclupuserythematosusand dementia Psychol Rep 1998, 83:1034 Jonsson H, Nived O, Sturfelt G: Outcome in systemiclupus erythematosus: a prospective study of ... prostaglandin E2 and autoantibodies in patients with neuropsychiatric systemiclupuserythematosusand central nervous system infections Scand J Rheumatol 1994, 23:57-63 18 Yeh TS, Wang CR, Jeng GW, Lee...
... criteria for the classification of systemiclupuserythematosus Arthritis Rheum 1982, 25:1271-1277 16 Jonsson H, Nived O, Sturfelt G: Outcome in systemiclupus erythematosus: a prospective study ... et al.: The development and initial validation of the SystemicLupus International Collaborating Clinics/American College of Rheumatology Damage Index for systemiclupuserythematosus Arthritis ... patients with systemiclupus erythematosus: association with clinical symptoms Arthritis Rheum 1998, 41:1181-1189 25 Sturfelt G, Hellmer G, Truedsson L: TNF microsatellites in systemiclupus erythematosus- a...
... a candidate chromosome region to human systemiclupuserythematosus J Clin Invest 1997, 99:725-31 Lander ES, Kruglyak L: Genetic dissection of complex traits: guidelines for interpreting and ... Arthritis and Rheumatism Campaign References Block SR, Winfield JB, Lockshin MD, D’Angelo WA, Christian CL: Studies of twins with systemiclupus erythematosus: A review of the literature and presentation ... revised estimate of twin concordance in systemiclupuserythematosus Arthritis Rheum 1992, 35:311-318 Arthritis Research 10 11 12 13 14 15 Vol No Barton and Worthington Vyse TJ, Todd JA: Genetic...
... cells and the different subpopulations Data are given for healthy individuals (con) and for each of the patient groups analyzed: osteoarthritis (OA), rheumatoid arthritis (RA) andsystemiclupuserythematosus ... The percentages of CXCR5+ and CXCR3hi B cells are given for healthy controls (con) and patients with osteoarthritis (OA), rheumatoid arthritis (RA) andsystemiclupuserythematosus (SLE) 0.2 0.1 ... concentrations in sera Sera of healthy controls and of sera patients with rheumatoid arthritis, systemiclupuserythematosusand osteoarthritis were tested in a standard ELISA test A D450 of 0.06 corresponds...
... populations Materials and methods Mice and sera Female NZW and male BXSB mice were purchased, respectively, from Bomholtgard Breeding and Research Center (Ry, Denmark) and The Jackson Laboratory ... Anti-NPM-antibody-positive systemiclupuserythematosus (SLE) sera yielded homogeneous nuclear and nucleolar staining (e) The nucleolar staining was abrogated when the mAb and sera from mouse (b,d) ... antibody systemiclupuserythematosus (SLE) (a) and a male WB mouse (c) using a 2D PAGE-separated HL-60 cell protein map as the substrate (b,d) Mass spectra of the proteins bound by the SLE (b) and...
... staining and flow cytometry for ICOS expression Percentages of ICOS+ cells (panels c and d) and MFIs of ICOS+ cells (panels e and f) are shown CD4+CD45RO+ (panels c and e) and CD8+CD45RO+ (panels d and ... cells and CD8+CD45RO+ICOS+ cells, respectively, were as follows: active SLE, 1.80 and 1.25; inactive SLE, 0.45 and 0.40; and normal control individuals, 1.10 and 0.50 *P < 0.05, **P < 0.01, and ... pathogenesis of systemiclupuserythematosus In Dubois' LupusErythematosus Edited by: Wallace DJ, Hahn BH Baltimore, MA: Williams & Wilkins; 1997:69-76 Rekvig OP, Nossent JC: Anti-double-stranded DNA...
... response to DNA in murine systemiclupuserythematosus Scand J Immunol 2003, 57:525-533 Izui S, Lambert PH, Fournie GJ, Turler H, Miescher PA: Features of systemiclupuserythematosus in mice injected ... Stephan H, Mannherz HG, Moroy T: Features of systemiclupuserythematosus in Dnase1-deficient mice Nat Genet 2000, 25:177-181 Walport MJ: Lupus, DNase and defective disposal of cellular debris Nat ... (rhDNase) in patients with lupus nephritis Lupus 1999, 8:68-76 Macanovic M, Sinicropi D, Shak S, Baughman S, Thiru S, Lachmann PJ: The treatment of systemiclupuserythematosus (SLE) in NZB/W...
... the data and helped to draft the manuscript YA obtained consent from patients and collected the samples and patient data for the study, and participated in the coordination of the study and writing ... SLE: effects of interleukin-2 and transforming growth factor-beta Lupus 1999, 8:95-102 Bruce IN, Gladman DD, Urowitz MB: Premature atherosclerosis in systemiclupuserythematosus Rheum Dis Clin ... factor beta in atherosclerosis: novel insights and future perspectives Curr Opin Lipidol 2002, 13:523-529 Hahn BH: Systemiclupuserythematosusand accelerated atherosclerosis N Engl J Med 2003,...