... reverse transcription polymerase chain reaction; SLE, systemiclupus erythematosus performed using one-way analysis of variance When logtransformation failed to generate normally distributed data ... patients with systemiclupus erythematosus The poorer correlation between plasma BLyS protein levels and disease activity compared with that between BLyS mRNA levels and disease activity was striking ... protein Candidate BLyS mRNA isoforms include the full-length BLyS mRNA isoform, which encodes the full-length protein, and the alternatively spliced ∆BLyS mRNA isoform, which encodes a protein...
... t-test) Systemiclupus erythematosus disease activity assessment Primary outcomes for clinical disease activity included the Safety of Estrogens in Lupus Erythematosus National Assessment (SELENA) Systemic ... antinuclear antibody; SLE, systemiclupus erythematosus; SELENA, Safety of Estrogens in Lupus Erythematosus National Assessment; SLEDAI, SystemicLupus Erythematosus Disease Activity Index dose cohort ... Component Score; SELENA, Safety of Estrogens in Lupus Erythematosus National Assessment; SF-36, 36-item Short Form; SLEDAI, SystemicLupus Erythematosus Disease Activity Index as consultants to HGS WS...
... rheumatoid arthritis; SDI, SystemicLupus International Collaborating Clinics/American College of Rheumatology Damage Index; SLE, systemiclupus erythematosus; SLEDAI-2K, SLE Disease Activity Index 2000 ... was dramatically increased LN, lupus nephritis; SDI, SystemicLupus International Collaborating Clinics/American Society of Rheumatology Damage Index; SLE, systemiclupus erythematosus of blood ... patient, disease activity and disease-related damage were assessed at the time of blood donation using the SLE Disease Activity Index 2000 (SLEDAI-2K) [16] and the SystemicLupus International...
... properties, MPs have been associated with systemic inflammation or excessive risk of thrombosis in various diseases, such as rheumatoid arthritis (RA), systemiclupus erythematosus (SLE), vasculitis ... Disease Activity Score for 28 Joints; ESR = erythrocyte sedimentation rate; HC = healthy control; NA = not applicable; pSS = primary Sjogren's syndrome; RA = rheumatoid arthritis; SLE = systemiclupus ... microliter by the formula N = (MP × beads per tube/volume of plasma)/number of counted beads Measurement of sPLA2 activity and sCD40L and sCD62P content in plasma We assessed the functional activity of...
... classification of systemiclupus erythematosus; APS, antiphospholipid syndrome; BILAG, British Isles Lupus Assessment Group; F, female; M, male; SLEDAI, SystemicLupus Erythematosus Disease Activity Index ... standard nephelometric techniques Disease activity was scored using the SystemicLupus Erythematosus Disease Activity Index (SLEDAI) and the British Isles Lupus Assessment Group (BILAG) Instrument ... peroxidase; Ig: immunoglobulin; NC: normal controls; SLE: systemiclupus erythematosus; SLEDAI: systemiclupus erythematosus disease activity index; TAM kinases: tyro 3, axl, mer Acknowledgements...
... inflammatory process in systemiclupus erythematosus (SLE) and rheumatoid arthritis (RA) even though both Gas6 and sAxl in most of the patients were within the normal range [13] Systemiclupus erythematosus ... activity in systemiclupus erythematosus Rheumatology (Oxford) 2011, 50:1064-9 14 Katsiari CG, Liossis SN, Sfikakis PP: The pathophysiologic role of monocytes and macrophages in systemiclupus erythematosus: ... Pascual V: Type I interferon in systemiclupus erythematosus and other autoimmune diseases Immunity 2006, 25:383-392 37 Pascual V, Farkas L, Banchereau J: Systemiclupus erythematosus: all roads...
... patients had taken prednisone once Lupus disease activities were assessed using the SystemicLupus Erythematosus Disease Activity Index (SLEDAI) score [33] Active lupus disease was defined as a SLEDAI ... factor; LN: lupus nephritis; NK: natural killer; PBMC: peripheral blood mononuclear cells; rRNP: anti-ribosome ribonucleoprotein antibody; SLE: systemiclupus erythematosus; SLEDAI: systemiclupus ... SLE, systemiclupus erythematosus; SLEDAI, SLE disease activity index; Smith, anti-smith-antibody Page of 12 were prepared with the SYBR Green PCR Master Mix (Applied Biosystems, USA) and performed...
... of SystemicLupus Erythematosus Wael Habhab 243 Chapter 12 New Therapeutic Strategies in Lupus Nephritis Natasha Jordan and Yousuf Karim 255 Chapter 13 Cardiovascular Involvement in SystemicLupus ... been suggested Genetics and Epigenetic in SystemicLupus Erythematosus 13 especially in systemiclupus erythematosus (SLE) due to the decreased levels of activity and mRNA in SLE patients (Haug ... polymorphisms of systemiclupus erythematosus in Taiwan 2004;Ann Rheum Dis 63, 877–880 Chitrabamrung S, Rubin L, Tan EM Serum deoxyribonuclease I and clinical activity in systemiclupus erythematosus...
... Measure) – a novel visual method to assess the global burden of illness in patients with systemiclupus erythematosus Lupus 2000, 9:368-373 Reimus JL, Vingerhoets AJ, Soons PH, Korstanje MJ: Suffering ... studies in patients with rheumatoid arthritis [6], chronic obstructive pulmonary disease [7], systemiclupus erythematosus [8], psoriasis [9], vitiligo [10], and chronic pain [11] have provided ... and type diabetes was evaluated by computing these correlations for each subtype Fisher-z transformations of these correlations were used to examine whether these correlations differed significantly...
... Measure) – a novel visual method to assess the global burden of illness in patients with systemiclupus erythematosus Lupus 2000, 9:368-373 Reimus JL, Vingerhoets AJ, Soons PH, Korstanje MJ: Suffering ... studies in patients with rheumatoid arthritis [6], chronic obstructive pulmonary disease [7], systemiclupus erythematosus [8], psoriasis [9], vitiligo [10], and chronic pain [11] have provided ... and type diabetes was evaluated by computing these correlations for each subtype Fisher-z transformations of these correlations were used to examine whether these correlations differed significantly...
... of SystemicLupus Erythematosus Wael Habhab 243 Chapter 12 New Therapeutic Strategies in Lupus Nephritis Natasha Jordan and Yousuf Karim 255 Chapter 13 Cardiovascular Involvement in SystemicLupus ... been suggested Genetics and Epigenetic in SystemicLupus Erythematosus 13 especially in systemiclupus erythematosus (SLE) due to the decreased levels of activity and mRNA in SLE patients (Haug ... polymorphisms of systemiclupus erythematosus in Taiwan 2004;Ann Rheum Dis 63, 877–880 Chitrabamrung S, Rubin L, Tan EM Serum deoxyribonuclease I and clinical activity in systemiclupus erythematosus...
... cẳng chân gặp lành chậm -Vùng đầu tóc rụng lan tỏa, tóc khô xơ xác, ngả màu râu ngô, có tổn thương lupus dạng đĩa đầu thấy rụng tóc thành đám tròn, có đỏ da, dày sừng, teo da làm rụng tóc không mọc ... dạng: rụng tóc thành sẹo rụng tóc không sẹo Rụng tóc thành sẹo đầu thường đầu có ban đỏ dạng đĩa lupus đỏ, có đám đỏ hình tròn, có vẩy sừng gắn chặt ( dày sừng điểm nang lông) sau có teo da tạo ... nề chân bì, thâm nhiễm viêm lymphocytes thoái hóa dạng fibrin mô liên kết thành mạch máu -Dải lupus: thử nghiệm miễn dịch huỳnh quang trực tiếp chứng minh có lắng đọng hình hạt hình cầu IgG,...
... and their spouses in Icelandic systemiclupus erythematosus multicase families Lupus 2002, 11:435-442 Herrmann M, Voll RE, Kalden JR: Etiopathogenesis of systemiclupus erythematosus Immunol Today ... individuals and persons with systemiclupus erythematosus Arthritis Rheum 2002, 46:1417-1429 Casciola-Rosen LA, Anhalt G, Rosen A: Autoantigens targeted in systemiclupus erythematosus are clustered ... Harley JB: The genetics of systemiclupus erythematosus: putting the pieces together Genes Immun 2002, (Suppl):S71-S85 Tsao BP: An update on genetic studies of systemiclupus erythematosus Curr...
... GR, Dorner T, Lipsky PE: Enhanced mutational activity and disturbed selection of mutations in V(H) gene rearrangements in a patient with systemiclupus erythematosus Autoimmunity 2000, 33:61-76 ... zone was observed surrounding either GC Immunohistochemistry of sections from a patient with systemiclupus erythematosus (a) Anti-FDC (follicular dendritic cell) staining within the area known ... http://arthritis-research.com/content/5/2/R114 Table Figure The replacement : silent ratios of sequences from each of the systemiclupus erythematosus splenic germinal centres and Bcell clusters GC A GC B (a) Location GC/cluster...
... APRIL and BLyS can form BLyS/APRIL heterotrimers (BAHTs), which have ‘BLyS-like’ biologic activity in vitro and which circulate in vivo [25] Whether BAHTs exert in vivo biologic activity and, even ... stimulator in systemiclupus erythematosus J Immunol 2001, 166:6-10 14 Cheema GS, Roschke V, Hilbert DM, Stohl W: Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based ... Ullrich S, Nardelli B, Hilbert DM, Migone TS: BLyS and APRIL form biologically active heterotrimers that are expressed in patients with systemic immune-based rheumatic diseases J Immunol 2002, 169:4314-4321...
... criteria for the classification of systemiclupus erythematosus Arthritis Rheum 1982, 25:1271-1277 Gladman DD, Ibanez D, Urowitz MB: Systemiclupus erythematosus disease activity index 2000 J Rheumatol ... Association of increased interferon-inducible gene expression with disease activity and lupus nephritis in patients with systemiclupus erythematosus Arthritis Rheum 2006, 54:2951-2962 Tan EM, Cohen ... Effect of lupus erythematosus patients systemic TNF stimulation on gene expression in healthy individuals Effect of TNF stimulation on gene expression in healthy individuals and and systemic lupus...