... gyrus, the right thalamus, the cerebellum, and the pons), within-subject analysis of EOS patients alone revealed that there were significant associations ofthe volume in these areas and the symptom ... regions denote areas of grey matter deficits in the early onset schizophrenia group relative to the control group The left side ofthe figure represents the right side ofthe brain; the z coordinate ... regions denote areas of white matter deficits in the early onset schizophrenia group relative to the control group The left side ofthe figure represents the right side ofthe brain; the z coordinate...
... team oftheMagneticResonanceImaging group in the Singapore Bioimaging Consortium (SBIC) I am grateful for all their help in conducting the MR spectroscopic imaging in the final part of my ... SYNTHESIS OF SUPERPARMAGNETIC NANOSTRUCTURES AND THEIR MAGNETICRESONANCEIMAGING APPLICATIONS CHOO SHI GUANG, EUGENE (B APPL SCI., HONS), NUS A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... this thesis, the study was aimed at improving current superparamagnetic contrast agents utilized in magneticresonanceimaging (MRI) For this purpose, the synthesis of well-defined spherical magnetic...
... words, the larger the particle size ofthe IOs, the stronger the magnetization The diffusion time τ D is the time during which the protons ofthe water molecules experience themagnetic field ofthe ... influence the relaxation rates are the magnetization ofthe IOs and the diffusion ofthe water molecules in the surrounding medium The magnetization ofthe IOs is directly correlated to its size In other ... rates of IOs The two main factors that influence the relaxation rates are the magnetization ofthe IOs and the diffusion ofthe water molecules in the surrounding medium Depending on the rate of...
... comparison with unmodified virus, increased tumor cell transduction is achieved with adenoviruses with RGD moieties in the HI loop ofthe fiber or in the KKTK domain ofthe fiber [30] Furthermore, ... replication in the liver tumors The growth of liver metastasis was analyzed withmagneticresonanceimaging (MRI) Tumors are marked with arrows Picture of liver metastasis of mock treated (PBS) animal ... Adenoviruses with an avb integrin targeting moiety in the fiber shaft or the HI-loop increase tumor specificity without compromising antitumor efficacy in magneticresonanceimagingof colorectal...
... radiological evidence of OA ofthe affected knee on a radiograph obtained within six months ofthe outset ofthe study Finally, patients had to have a minimum JSW ofthe medial compartment of between and ... between the level ofthe biomarker and the loss of cartilage volume assessed by qMRI (global, medial, and lateral compartments), or between the level ofthe biomarker and the changes in JSW The r ... OA We hypothesize that the slow progressors might constitute a subgroup of patients in a quiescent phase ofthe disease Many consider the measurement ofthe change in the minimal JSW of standardized...
... but not by MRI (Figure 3a) In two ofthe patients in whom zygapophyseal joints were MRI- negative, signs of osteitis were seen at other sites ofthe spine: in the vertebral bodies of thoracic ... correlation of histopathological analysis ofthe spine and inflammation as visualized by MRI has also not previously been done In the sacroiliac joints of patients with AS, a correlation ofMRI findings ... marrow edema in histopathological assessment and magneticresonanceimaging (a) Magneticresonanceimaging (T2 imaging sequence) of a zygapophyseal joint with bone marrow edema (cyan arrow) (asterisk,...
... time as the disease progressed The relationship between the worsening in the WOMAC scores withthe loss of cartilage on the central portion ofthe tibial plateau is intriguing The level of significance ... analgesics or NSAIDs, withthe exception of indomethacin [14], the regimens of which could be changed according to the preference ofthe rheumatologist and the clinical course ofthe patient Such ... topographical loss of cartilage in the different subregions ofthe knee and the associated risk factors Moreover, the impact ofthe location and rate of cartilage loss on the evolution of OA symptoms...
... Although this MRI pattern is highly suggestive ofthe lymphoma, there is no absolute correlation between theimaging morphology and the histology ofthe lesion [7] In this case, our patient’s MRI showed ... many ofthe nodules may consist of follicles with reactive germinal centers surrounded by broad mantles of small lymphoid cells or the so-called mantle zone pattern [2] Later in the course ofthe ... appearance reflected the histological pattern ofthe lesion as MCL was composed of neoplastic nodules which were adjacent to the cystic area To the best of our knowledge, there are no other published...
... patients Increase of serum levels of alkaline phosphatase (ALP) was the earliest indication of HO MRI, magneticresonanceimaging tomic position ofthe innermost part ofthe vastus medialis (Figure ... disclosed the capability ofMRI to detect early HO changes From the clinical point of view, the risks of transporting critically ill patients and the cost ofthe method could pose limitations in the ... after the first clinical suspicion of HO X-rays performed at the same time revealed no abnormality To the best knowledge ofthe authors, the 'lacy pattern' in the affected muscles on MRI is the...
... come from the dT parameter ofthe sigmoidal t ofthe melting curve, which negatively correlates withthe cooperativity ofthe thermal transition Error values were derived from the average of several ... an abundance of UDE mRNA as well as of domain V of 23S rRNA These results, together withthe characteristics ofthe two distinct conformational states, suggest putative cofolding of UDE and RNA ... suggest the potential existence of two separate conformational states ofthe protein, one of these containing a signicant amount of associated nucleic acid To address the potential signicance of these...
... for the presence of known localization factors Input corresponds to 1% ofthe material used in the pulldown experiment The presence ofthe TAP-Vg1RBP band in the anti-Staufen blot is a result of ... anchoring to cortical actin upon arrival ofthe RNP at the vegetal pole ofthe oocyte In the context of these localizing RNPs, but also as integral part ofthe 42S storage particle, 42Sp50 might ... ofthe strong binding of secondary anti-rabbit serum to the protein-A moiety ofthe TAP-tag Anti-CBP serum was used to show the expression ofthe TAP-tag alone lysate from oocytes expressing the...
... interacting withthe protein, because theresonance signals ofthe glucose residue overlapping with those ofthe galactose residue within the lactose affected the subtraction ofthe free induction ... interacts withthe region of H1 and the O-methyl group The crystal structure of EW29Ch with lactose showed that the O2, O3 and O4 atoms ofthe galactose residue of lactose formed hydrogen bonds with ... ofthe chemical shift titration data to the binding isotherm [27] A plot ofthe weighted average chemical-shift changes of 1H and 15N resonances for the cross-peaks of Gly122, as a function of...
... association of 4E-BP1 with eIF4E (Fig 7B) As pretreatment of cells with any of these inhibitors alone, or in combination was unable to prevent the global inhibition of protein synthesis observed with ... investigation into the regulation of protein synthesis in mammalian cells, we have investigated the effects of inhibition ofthe proteasome on the localization and integrity of eIF4G in C2C12 ... in the migration of endothelial cells and in recovery of cells from wounding [40] In a variety of cells, in addition to the induction of hsp25 and aB-crystallin expression, inhibition of the...
... characteristic ofthe monoformazan, i.e the fully reduced product of INT [15,17] In the following aeration ofthe medium, the absorbance ofthe spectral bands decreased, but the shape ofthe spectrum ... inward The rates of oxygen uptake were deduced from the slopes ofthe tangents to the oxygraphic traces, and the contact points ofthe tangents withthe curves were used to determine the O2 concentrations ... [13], either by measurement ofthe rate of production of O2– or the rate of O2 uptake INT diaphorase activity was assayed by the rate of reduction of INT into formazan in the presence of superoxide...
... diluting to one ml isoflurane per gallon of water with isoflurane and was pumped up from the vat to the fishs oral cavity, over the gills and backed through the tabletop to the bucket again [1,3] ... to the table, where three tubes for maintaining anesthesia were placed in both mouth and gills The water with isoflurane used in induction anesthesia was also used in maintaining anesthesia with ... oviposition period [6] In addition, because they live on theSurgical removal of stones in the stomach of a tiger shovelnose catfish bottom of water, they have more chances to face stones [6] Generally,...
... direct proof of our main theorem, Theorem 6, as follows Proof of Theorem We fix a natural number n Consider the graphs Rn and Ln We will show that Rn and Ln have the same number of circuits of each ... derivative of ZX (u) is a generating function for the number of circuits See for instance [7] Knowing the number of circuits of each length is sufficient to conclude the number of primitive circuits of ... only if they have the same number of primitive circuits of identical lengths Proposition Let X and Y be graphs For all natural numbers k, there is the same number of primitive circuits of length...
... duration of more than eight years between the start of symptoms and the diagnosis of AS is reported [3,4] Such a delay is increasingly unwarranted because ofthe availability of effective treatment Magnetic ... effective treatment Magneticresonanceimaging (MRI) is an imaging modality that may shorten the delay between the start of symptoms and a classifying diagnosis of AS or SpA since MRI can detect inflammation ... SI joint in the subchondral region (the region adjacent to the cortical lamella, extending 0.5 cm into the bone marrow cavity), the bone marrow, the joint capsule (the transition ofthe joint space...
... patients with dactylitis ofthe toes; MRIof toes 0.5 PsA patients with dactylitis ofthe fingers; MRIof fingers 1.5 Olivieri [22] 2003 PsA Patient with dactylitis of fingers; MRIof fingers ... example of bone oedema from a patient withthe mutilans form of PsA There is extensive bone oedema involving the head ofthe proximal phalanx and extending down the shaft ofthe bone On the distal ... described theMRI features of enthesitis as being characterized by ‘swelling [of the entheseal region] and deviation from the normally uniform low signal intensity of tendons and ligaments, [with] ...