... breast cancer and who are atan intermediate risk of local recurrence into the current UK trial (SUPREMO) assessingthevalueofpostoperativeradiotherapyPatientsatan intermediate risk of local ... responsibility of healthcare professionals to make decisions appropriate to the circumstances ofthe individual patient, in consultation with the patient and/or guardian or carer, and informed by the summary ... important There is currently a variation in the provision and quality of psychological approaches and services offered to patients with breast cancer As a consequence ofthe diagnosis of breast cancer...
... data from the publications, or where possible, adjusted ORs Meta-analysis was carried out to estimate the effects on the risk of LRI of smoking by the mother only, father only, both parents, and ... when the studies were categorised by methodological quality, date of publication, and by study design Effects of paternal smoking Meta-analysis ofthe 21 studies of paternal smoking demonstrated ... causes a statistically significant increase in the risk of infants developing lower respiratory infections in the first two years of life, and provides further precision in the estimates ofthe magnitudes...
... recombinant MMP-1, 0.04 ng/ml of human recombinant MMP-3, 0.24 ng/ml of human recombinant MMP-9, and 0.031 ng/ml of human recombinant TIMP-1 with an inter-assay variation of less than 10% The results ... conceived the study, participated in the design ofthe study, performed the statistical analysis and drafted the manuscript All authors read and approved the final manuscript Competing interests The ... dysfunction [10] These findings together point to the need to increase our understanding ofthe role of MMPs in AD and their relation to other AD-related markers in vivo Investigation of markers in...
... (A and B) and HepG2 cells (C and D) were left untreated or treated with SA (5 mM) for the indicated time and harvested The upper panels in (A) and (C) show the northern blot analysis of HO-1 and ... to the intensity of 18 S rRNA The ratio of each normalized value to the control valueat time (0 h) is shown as the relative expression level of HO-1 or HO-2 mRNA The data are mean ± SEM from three ... respect to the intensity ofthe b-actin signal The ratio of each normalized value to the control value in siRNA-untreated cells (control) is shown as the relative expression level of HO-1 or...
... is the first study to examine the expression of OPN and its receptor, CD44, in the spinal cord of rats with EAN Many studies of EAN have investigated the pathologic changes in the target organ, ... as the EAN model Glial cell activation and appearance of macrophages in the rat spinal cord in EAN To examine the activation of spinal cord cells in EAN, we performed immunostaining for ED1 and ... organ, the sciatic nerves, in the rat 292 Changjong Moon, Taekyun Shin Table CD44 and osteopontin immunoreactivity in the spinal cords of normal and CFA-immunized control rats, and rats with EAN Antibody...
... smoking status (Table 1, Table 2) Any questions or discrepancies regarding these data were resolved through iteration and consensus Statistical analysis We used the annual change in the rate of FEV1% ... responsible for the increased susceptibility of women to cigarette smoke are largely unknown There is now a general consensus that inflammation is atthe heart ofthe pathobiology of COPD and that the inflammatory ... inflammatory process involves both the lung (airways and parenchyma) and the systemic circulation [32-34] The intensity ofthe inflammatory process in the airways and in the systemic circulation...
... assessed the occurrence ofpostoperative delirium, collected thepatients data, and drafted the manuscript D-XW designed the study, performed the statistical analysis, and revised the manuscript and ... fibrillation on the 1st and 3rd postoperative day, respectively Because of unarousable sedation or coma, these two patients were not assessed for delirium The other two patients died of circulatory ... found that an older population and patients with diabetes mellitus have an increased baseline cortisol level and an attenuated negative feedback mechanism that inhibits further secretion of cortisol...
... samples of 50 μl of whole blood and appropriate controls were incubated in duplicate with saturating concentrations ofan anti-lipid A IgM antibody, and then stimulated with opsonized zymosan The ... Fifty-seven patients were enrolled One patient was excluded from the analysis because of lack of EAA data and patients were excluded because of withdrawal of consent resulting in a sample size of 54 patients ... surgery The finding of a substantially increased risk of post-operative infections in patients who have endotoxemia after CPB is novel Given the elective nature ofthe surgical patients and their...
... than four times larger material The next strategy, which is the basis ofthe present study, is continued surveillance This necessitates the presence ofan ongoing surveillance system which is the ... loratadine-exposed infants was highly significantly lower than that during the first period There are two possible explanations The noticed effect of loratadine during the first period could be the result of a ... with the Swedish Medical Birth Register The followup performed gave no evidence for an association between maternal use of loratadine and hypospadias and the rate of hypospadias among loratadine-exposed...
... understand the mechanisms of uncoupled bone turnover and effects of PI therapy on HIV infected patients As the number and life expectancy of HIV-positive patients treated with HAART increases, the ... consideration before the onset ofthe treatment of HIV-infected patients Abnormal laboratory values of elevated alkaline phosphatase or low testosterone obtained during the course of HIV treatment ... humans, these scientific advances are need to be made in an environment of legal and ethical safeguards that are acceptable to the general public [44] Fig Normal variation (mean and 8D) and change...
... (15) V.T.H Thanh et al / VNU Journal of Science, Mathematics - Physics 25 (2009) 57-68 65 From (13), (14) and (15), the assertion ofthe corollary follows 2.2 The proof ofthe main theorem Lemma ... (s3) are the values in Corollary From Lemma 2, Corollary and Proposition 2, we have Theorem Let µ is the 5−fold convolution ofthe standard Cantor measure, then the lower extreme valueofthe local ... and the associated probability After that, in [5], Pablo j=1 Shmerkin showed the αm for m = 2, 3, by the other way He used the spectral radius of matrixes to define his results He said that the...
... task, but with the provision of c o n t e x t s w h i c h are f e l i c i t o u s w i t h one or other ofthe two versions of their examples the with the to NP) In the case ofthe n o n - m i ... o n , and the i n f o r m a t i o n c o n t a i n e d within the relative must therefore be matched against information which already exists in the hearer's model ofthe universe This matching ... (1974) and Wanner (1980) m o d e l t h e s e e f f e c t s u s i n g an ATN, and s h o w that they can be made to arise from peculiarities ofthe o r d e r in w h i c h arcs leave certain states...
... estimate the number of subsites and the position ofthe catalytic site (d) Apply a minimization process to test the differences of measured and calculated BCF data The present studies were aimed at ... shows the structure ofthe program The supposed number of subsites and the position ofthe cleavage site can vary according to the calculations The primary calculated subsite energy values can be ... be refined to the best agreement ofthe measured and recalculated BCF data by the iteration Fig shows the flow diagram of iteration The graphical illustration of iteration appears in the ‘Chart’...
... Therefore, the diameter and location ofthe SiNW are determined by the features ofthe catalyst particle [20] Thus, it is important to control the catalyst size distribution and the delicate catalyst ... formation of only a few of SiNWs The reaction temperature is usually decided with the consideration ofthe catalyst type According to the binary phase diagram of a metal and Si, the temperature ... distribution can be well-organized by using a nano-channel-alumina (NCA) technique [11] Otherwise, the pressure of reaction channel and temperature are also important for the growth of SiNWs In the present...
... Experiment These two examples not suggest any kind of proof, but they well illustrate the recognition power of even the least powerful automaton in the {LeA(i)} family To get another point of view, ... somewhat larger for the small subset ofthe most common words) 156 - underlying grammar, and by L(k) the language accepted by the automaton LCA(k) The following relations hold for the family of ... with four valid paths through the sentence, out ofthe 256 tentative paths in SG Two paths represent legal syntactic interpretations (of which one is "the intended" meaning) The other two are locally...
... ¯ Proof The proof is analogous to the proof of [48, Lemma 1.6.3], but we need the proof of [37, Th A] and not just the statement We consider the bi-simplicial category T(C) whose category of (p, ... homotopy cartesian Moreover, the composite ofthe maps in the lower row is equal to the map ofthe statement, and the upper left-hand and upper righthand terms are contractible Hence the theorem is ... to eK in each degree Hence the dimension ofthe range is at least eK in each degree We can estimate the dimension ofthe range further by means ofthe exact sequence of k-vector spaces i! j∗ ∂...
... in the substrate-binding pocket, with an atomic distance between the functional ˚ oxygen atom and the catalytic Zn shorter than 3.16 A Moreover, the distance between the O atom of retinoids and ... cycles, allowing free movement ofthe rotatable bonds ofthe ˚ substrate and ofthe v angles ofthe residues inside a A radius from the docked substrate, and using distance restraints as described ... physiologically, but their kinetic study gives an estimate ofthe effect ofthe cisbond position on the substrate specificity of human ADH4 The 7-cis- and 9-cis-retinol and retinal isomers were the most active...