... P values are for the comparison withsuddendeath or cardiac arrest with resuscitation tion of more than 40 percent, the rate of suddendeath or cardiac arrest with resuscitation was more than ... been seen within 24 hours before death but had not had premonitory heart failure, myocardial infarction, or another clear cause of deathCardiac arrest with resuscitation was defined as cardiac ... suddendeath in the group with the lowest ejection fraction after 90 days Moreover, patients who died suddenly or had cardiac arrest with resuscitation were in clinically stable con- Sudden Death...
... stained with bcl2; - I (weakly positive): to 50% of tumor cells stained with bcl-2; - II (strongly positive): over 50% of tumor cells stained with bcl-2 Since statistical analysis did not reveal ... followed by three 5-min baths with PBS buffer The DAB kit was used for development Counterstaining was carried out with Harris hematoxylin for 20 s after serial rinsing with tap water, 2% ammonia ... metastases and one for disease in the axilla, all with palliative intent Immunohistochemistry Sections of paraffin-embedded metastasis specimens were initially stained with hematoxylin-eosin...
... (40.5) 0.90 (AG genotype versus AA genotype) MHC2TA -168 GG genotype (n (%)) 23 (6.4) 37 (10.5) 0.044 (GG genotype versus AA + AG genotypes) 0.278 0.308 MHC2TA -168G frequency DMARDS, disease- modifying ... genotype versus AG + AA genotypes; P = 0.167, OR = 0.726, 95% CI = 0.462–1.141) The MHC2TA gene among Austrian RA patients was not significantly associatedwith rheumatoid factor positivity, with ... our matched controls we additionally genotyped a larger control group, but the genotype frequency was similar genotype might not be directly associatedwith RA A strong association between RA-specific...
... patients, is in line with other studies in patients with SLE [1,31] With respect to major infections, use of immunosuppressive medication and use of corticosteroids were notassociatedwith the occurrence ... deposition was associatedwith plasma C4 levels in healthy controls and patients with SLE [27] In that study, MBL levels were correlated to C4 deposition in healthy controls but not in patients with SLE, ... significantly associatedwith infections and major infections, the demographic, clinical, and therapy variables with a p value of less than 0.2 in the univariate analyses and variables with supposed...
... comprising two of each genotype Page of (page number not for citation purposes) IFIH1 A946T is notassociatedwith RA susceptibility or severity Allele and genotype frequencies for IFIH1 A946T were in ... [14] Genotypes were not significantly different, indicating that this polymorphism is not a susceptibility gene for RA (Table 1) To determine whether this marker influenced the disease phenotype, ... twins supporting a genetic input [17] We did not detect Table Genotype frequencies of the interferon induced with helicase domain A946T polymorphism Genotype frequency GG AG AA Patients 126 (13.7%)...
... ipsilateral longer leg, and 17 cases with bilateral GTPS) and in 163 subjects without GTPS; therefore, 13.7% of subjects with GTPS had a LLI compared with 14.1% of those without GTPS (P = 0.86 by Fisher's ... those with generalized myofascial tenderness) Additionally, treating LLI as a continuous variable and adjusting for age and sex, LLI was notassociatedwith GTPS Separate regression analyses (1) without ... cm with a range of 67.7 to 169.5 cm The LLI ranged from to 6.4 cm A categorical LLI (difference ≥ cm) was present in 37 subjects with GTPS (nine cases with ipsilateral shorter leg, 11 cases with...
... presence of the metabolic syndrome in patients with rheumatoid arthritis: a cross-sectional study Arthritis Res Ther 2008, 10:R145 Page of (page number not for citation purposes) ... Greece References Toms TE, Panoulas VF, Douglas KMJ, Kitas GD: Methotrexate therapy associates with a reduced prevalence of the metabolic syndrome in rheumatoid arthritis patients over the age...
... 1100delC variant differs within various populations [5] It was found in 0.9% of the Northrhine-Westphalia population [13] The CHK2 1100delC variant has been associatedwith breast cancer in multiple-case ... that the I157T variant appears to be associatedwith a decreased risk for developing lung cancer and laryngeal cancer [30] In this case, CHK2 alterations may be not predisposing but protective for ... CHEK2 associatedwith prostate cancer risk Am J Hum Genet 2003, 72(2):270-80 Seppala EH, Ikonen T, Mononen N, Autio V, Rokman A, Matikainen MP, Tammela TL, Schleutker J: CHEK2 variants associate with...
... SNP withdisease is not the same in all patient groups and categories, as has been noted in previous studies that could not always confirm the originally observed association of the -945GC SNP with ... differences for the -945CG polymorphism with plasma CTGF levels in DN and NA patients with diabetes We found that plasma CTGF levels were notassociatedwith this polymorphism, which further questions ... was no difference in CTGF levels between genotypes (Figure 1) Also, linear regression analysis could not predict plasma CTGF levels from genotype (not shown) The mean follow-up time in the diabetic...
... neither genotypes nor alleles were associatedwith periodontitis, even after adjusting for covariates, including age, gender and smoking status (Table 2) Therefore, this polymorphism could not be ... envisaged aiming prevention of disease establishment However, many studies with different populations would be needed to reach a high-risk profile for periodontal disease [16] Another important point ... study with forensic microsatellites Hum Hered 2006, 62(4):190-195 doi:10.1186/1477-5751-10-14 Cite this article as: Scarel-Caminaga et al.: Variation in the CXCR1 gene (IL8RA) is notassociated with...
... patients are sporadic (SALS), not showing any familial trait Approximately 10% of cases are familial (FALS), and within these lie several distinct forms of the disease The most common form of ... ALS1, with adult-onset caused by mutations in the gene encoding the cytosolic antioxidant enzyme Cu, Zn-superoxide dismutase (Sod1) [1,2]; and ALS4, a rare juvenile-onset disorder, associatedwith ... area, suggesting that this aminoacidic substitution is not causative of the disease The data presented herein suggest that VAPB mutations are not a common cause of adult-onset SALS in Italian population...
... that patients with positive tumors for MMP1 and MMP3 had a shorter disease- free survival when compared to those with negative lesions (MMP1, p = 0.0383; MMP3, p = 0.0294) [7] In another study, ... panel Although this difference was not significant (p = 0.73) The 5A allele was more common in patients with low Clark level melanomas (p = 0.04) and with tumors with infiltrating lymphocytes (p ... when individuals with the C-1306-C-735 haplotype were compared to subjects with the T-1306-T-735 haplotype (OR = 6.53; 95% CI = 2.78–15.33) [11] The MMP3 5A allele was associatedwith a poorer prognosis...
... iron absorption One possible underlying intestinal diseaseassociatedwith impaired iron absorption is celiac disease [3,4] Previously, celiac disease was usually considered in patients who had ... in patients with iron deficiency appears to be even more complex since not all patients Page of (page number not for citation purposes) Journal of Medical Case Reports 2008, 2:96 with iron-deficiency ... judged to be increased and not dysplastic An iron stain revealed clearly decreased storage iron Other findings were normal Notably, the typical signs of myeloproliferative disease syndrome such as...
... activity and erosive disease [10,20] Higher IgM-RF levels have been associatedwith a higher risk for the development of RA[23] IgM-RF levels also seem to be associatedwith future radiographic ... in the first year were not correlated with the two-year outcome measures (all P > 0.10) ACPA or IgM-RF-negative patients were not further analysed since their levels did not change significantly ... were that baseline levels were only marginally associatedwith later radiographic damage The firstyear change in IgM-RF levels was modestly associatedwith SHS at the two-year follow up; however,...
... group treated with pravastatin [16] SNP genotyping rs10818488 was genotyped in the RA cohort and rs2416808, which is in complete linkage disequilibrium with rs10818488 (r2>0.99), was genotyped in ... enrolled patients with a median disease duration of 10 (range to 18) years, which were subsequently followed up for two to four years, CVDrelated deaths occurring earlier in the disease course may ... were determined with Haploview [17] Both SNPs were in agreement with Hardy-Weinberg equilibrium Both rs10818488 and rs2416808 are in complete linkage-disequilibrium with rs3761847 genotyped by Panoulas...
... compared with Student's t test or analysis of variance for normal values, or with the Mann-Whitney test for nonparametric data p < 0.05 was considered to denote statistical significance The factors associated ... associatedwith bleeding during ICU stay were also studied with multivariate analysis Variables with p < 0.25 in univariate analysis were selected A multivariate logistic regression model with bleeding ... The characteristics of the patients with clinical evidence of bleeding (excluding those with extra-digestive bleeding) were compared with those of the patients without bleeding (Table 3) Survival...
... closely associatedwith the MAPK pathway and 10 with cell signaling such as TCR and chemokine and cytokine pathways Unique pathways associatedwith non-progressive HIV disease Among the 15 MAPK -associated ... the patients, assisted with clinical follow up and details; WBD assisted with LTNP samples, intellectual input with LTNP biology, assistance with writing; YHY assisted with the mathematical and ... the VIR group with the BDL/LTNP groups In comparing the VIR and LTNP groups, 25/66 genes in this pathway were the core enrichment genes associatedwith the VIR group, such as the death receptor...
... admission was not (Tables and 8) Results were similar with SAPS II expected mortality instead of APACHE II expected mortality (not shown) Discussion In this retrospective cohort study with prospectively ... studies one cannot judge the quality of off-hour ICU care in general, but we can conclude that off-hour care is not necessarily inadequate For ICU managers Page of (page number not for citation ... of (page number not for citation purposes) Available online http://ccforum.com/content/13/3/R84 different groups within the surgical group The study was performed in three ICUs with intensivist...