... Discussion The results of this pooled analysisof two phase III studies indicated that initial use of doripenem in patients with VAP was associated with shorter durations of mechanical ventilation ... other studies [4-6] because of activity against key pathogens Consideration of the influence of appropriateness of empiric therapy against subsequently identified pathogens was beyond the scope of ... cost of hospitalization as demonstrated in a recent economic analysisofstudies and [29] Using discrete event simulation, Kongnakorn and colleagues [29] estimated that use of doripenem instead of...
... devised, G.R Sampson began the task of drawing tree diagrams of the constituent analysisof sample sentences ca computer print-outs of the word tagged version of the corpus As tree drawing proceeded, ... fields of data on each record of a serial file• The fields or col,lmns of data are:- (i) a reference number, (2) a word token of sample text, (3) the word tag for the word and (~) a field of hypertags ... Comparison of results with sections of samples from the tree bank enables a more empirical validation of the entries by checking the output of the T-tag look up procedure against samples of the corpus...
... 2005 FEBS 283 Computer- assisted mass spectrometric analysisof cross-links L J de Koning et al Fig Part of the output sheet of the VIRTUALMSLAB analysisof the MALDI-FTICR-MS data of the RNase ... new avenues in the computer assisted analysisof more complex biological assemblies, by combining advanced peptide separation techniques A B Fig MALDI-TOF ⁄ TOF MS ⁄ MS analysisof a NK1 cross-linked ... available software suffers from limitations, often preventing general application in crosslink analysis [6] Here we demonstrate several features of the virtualmslab program for protein cross-link analysis...
... Intensity of cytoplasm Ratio of Translocation = Intensity of nucleus Intensity of cytoplasm Intensity of nucleus Scheme This is a simplication of a cell as seen by analysis software, where the software ... method ofanalysis (in vitro, cell-based and in silico analysis) will facilitate systematic understanding of the underlying properties of this signaling pathway To summarize Activation of cells ... cell-based measurements of time-varying phenomena, in this case, oscillatory variations of nuclear levels of NF-jB In order to attain this degree of precision, optimization of experimental conditions...
... results of their analysis will be useful in determining the impacts of primary particulate emissions from OGVs upon worldwide communities downwind of port operations In the same region of Southern ... air pollution - an analysisof recent studies Journal of Occupational Medicine and Toxicology 2011 6:31 Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online ... with increase of OC and sulfate Interestingly, cooling of the exhaust as well showed an effect on the quantity of polycyclic aromatic hydrocarbons (PAHs) absorbed on the surface of particulates...
... rotten) and a set of data for knot pith line and diameters of a series of knot cross-sections [23, 24] The scanned images of all the flitches of the logs from one tree containing a total of 245 knots ... tree height in intervals of 5% of tree height RESULTS The results obtained with the computer- aided reconstruction of logs are exemplified in figure where the reconstitution of two logs (one butt ... application of a 3D -computer- aided stem and log reconstruction software, based on input information obtained by image scanning, to twenty 83 years old Maritime pines The stem/log reconstruction is a software...
... safety of DVPX in various indications The FDA suicidality meta -analysis of the 11 AEDs included a total of 199 placebo-controlled clinical studies (43,892 subjects) and 11 low-dose-controlled studies ... placebo-controlled studies and study comparing a high-dose with a low-dose of DVPX Descriptions of the studies and corresponding numbers of subjects included in the analyses are presented in Table All studies ... present analysis, treatment with DVPX in a variety of conditions did not appear to increase the risk Page of 10 of suicide-related AEs relative to that of placebo, consistent with the DVPX OR of 0.72...
... analyzed in many studies Only seven of 20 studies reported 186 cases of such patients in current review [3-5,27-29] To avoid high bias-risk of publication, we did not perform an analysisof BC-HCC group ... data of subsets of patients The characteristics of these 20 studies are summarized in Table Patients Characteristics Results from overall meta -analysis are outlined in Table The mean age of patients ... carried out the extraction of data, assisted in the critical appraisal of included studies and assisted in writing up YZ, ZZ, and BL carried out the statistical analysisofstudies All authors read...
... Outcomes of cohort studies All cohort studies Outcome Number of cohorts Only definite nephritis Number of Percentage events/patients with outcome Number of cohorts Any SLE patients Number of Percentage ... any study, this is a rate of 0.2% over the course of an average treatment period of at least year Discussion Meta -analysis of small studies is problematic [63] because of possible inadequacies ... QUOROM (quality of reporting of meta-analyses) and MOOSE (meta -analysis of observational studies in epidemiology) guidelines were followed where applicable [19,20] Studiesof any design and in any...
... assessment of disease activity, and the WOMAC™ questionnaire total score) [6,7] Here, we report on a pooled analysisof the above two studies This analysis evaluated the effectiveness of lumiracoxib ... parallel-group, 13-week studiesof patients with OA of the knee and of identical design was conducted Methodology for the studies has previously been described elsewhere in detail [6,7] and both studies were ... according to PASS during and at the end of the study period and on patient achievement of sustained satisfaction by PASS Materials and methods A pooled analysisof data taken from two international,...
... 55% and DLCO < 40% of predicted) have a worse prognosis, with a mortality of 42% within 10 years of the onset of disease [5] A number of agents have been evaluated for treatment of SScrelated ILD ... therefore imputed the mean value of the standard errors of the other studies, and performed sensitivity analyses across the range of reported standard errors of these studies We used a random-effects ... meta -analysis The overall pooled analysis included the mean changes of the FVC and the DLCO after 12 months of therapy obtained from the observational studies and from the CYC experimental arm of...
... genome-wide association studies; RA, rheumatoid arthritis Competing interests This study was financially supported partly by the grant from the Ministry of Health, Labor and Welfare of Japan Author details ... Gorlova OY, Amos C, Logothetis CJ: GWAS meets microarray: are the results of genome wide association studies and geneexpression profiling consistent? Prostate cancer as an example Plos One 2009, 4:e6551 ... this article as: Sugino H, et al.: DNA microarray analysisof rheumatoid arthritis susceptibility genes identified by genome-wide association studies Arthritis Research & Therapy 2010, 12:401...
... consistency of results across studies and to identify regions that contain asthma and atopy susceptibility genes The aim of the current study was to complete the first meta -analysis of available ... region Analyses of the IgE Page of 12 (page number not for citation purposes) Page of 12 NUMBER OF. (b) COHORT (REF.) PHENOTYPES(a) PED (AFF/IND.) MKS WF MKR MAP (SP.)(c) STUDY TYPE(d) ANALYSIS PROGRAM ... meta -analysis of asthma and related trait linkage data using the majority of the data available for the Caucasian asthma cohorts in the public domain This analysis combines data from 10 years of...
... reported in 10 to 20% of patients with MD [34] In our sample about 54% (50 of 92) of adult MD patients and 79% (71 of 90) of pediatric MD patients also had signs and symptoms of PF, although incidence ... MEN, or MD, two-thirds (4 of 6) of the SBEs observed during the infusion period were ICHs (ICH rate 2.5%; of 163), whereas 13 of 100 SBEs were ICHs (ICH rate 0.4%; 13 of 3,088) in patients without ... of severe sepsis in the United States: analysisof incidence, outcome, and associated costs of care Crit Care Med 2001, 29:1303-1310 Martin GS, Mannino DM, Eaton S, Moss M: The epidemiology of...
... Methods Overview ofstudies analyzed In this retrospective efficacy analysis, data were pooled from three Canadian open-label studies [13-15] These trials assessed the effects of atomoxetine on ... three studies, regardless of the fact that the assessment times varied between studies, and could also allow inclusion of data from unscheduled visits and visits that occurred outside of prescribed ... 12 months of follow-up; the three studies varied in length from 3-12 months and in addition approximately 30% of children did not complete their study Therefore, we chose methods ofanalysis (survival...
... pigment-chimeric eyes of Xenopus: posterior half of the developing eye studied in genetic chimerae and in computer simulations Proceedings of the National Academy of Sciences of the United States of America ... question of what type of data would be most useful and how simulation modeling can suggest avenues of experimental investigation Embryogenesis is a period of profound growth We believe that one of ... Nudge++™ software environment; the software then regenerated the original tracings as computerized anatomical boundaries within the simulations (Fig 8) Computer simulations Nudge++™ is a robust computer...
... of modeling dependencies in detail refereed research As shown, the choice of category-detection method has a profound impact on the results of the ontological analysis However, the question of ... MDS component 0.2 The ontological analysisof genome-wide studies relies fundamentally on the validity and continued growth of ontologies providing annotations of gene function However, efficient ... parameters control the types of categories modeled: the number of genes in the category (N); the proportion of modulated genes (π); and the mean and standard deviation of the modulated gene scores...
... PLANT……………………………32 ISOLATION OF AN OSMOTIN-LIKE PROTEIN GENE FROM STRAWBERRY AND ANALYSISOF THE RESPONSE OF THIS GENE TO ABIOTIC STRESSES………………………………………………… 54 EXPRESSION OF A STRAWBERRY OSMOTIN-LIKE ... sites Binding of Ca++ to these sites caused inhibition of the antifreeze and chitinase activities of these complexes Strawberry is a member of the Rosaceae family, which consists of more than ... manufacturer’s protocol 2.3 Results 2.3.1 Analysisof Strawberry Chitinase Isoform Patterns To obtain information on strawberry chitinase activity, the isoform patterns of the enzyme in different strawberry...
... degree of a graph, we usually mean the maximum degree of its vertices When discussing the size of a graph, we typically consider both the number of vertices and the number of edges The number of ... a neighbor of u, we set d[v] = d[u] + Thus we have d[v] = d[u] + = δ(s, u) + = δ(s, v), as desired Analysis: The running time analysisof BFS is similar to the running time analysisof many graph ... of this process throughout the semester Lecture 2: Mathematical Background Read: Review Chapters 1–5 in CLRS Algorithm Analysis: Today we will review some of the basic elements of algorithm analysis, ...