structures based on dna condensation under osmotic stress
Báo cáo y học: "Determining promoter location based on DNA structure first-principles calculations" ppsx
... boundary conditions and Ewald summations [45] Simulations were carried out using SHAKE [46] on all bonds connecting hydrogens and fts time steps for integration of Newton equations of motions TIP3P ... the location of promoters of fast evolving genes or those appearing in anomalous positions that violate the traditional concept of gene structure Conclusion Atomic MD simulations, based on physical ... this comparison will give no information on ProStar with respect to 'state of the art' methods based on conservation of gene structure and orthology, but does give some indication of the ability...
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Effects of salt solutions on DNA micromechanics under tension
... REVIEW the DNA chain are assumed to depend only on the proportions of different states Hence, the extension of DNA is given based on the contributions of both B and S states Based on the same ... some solution condition dependent models are also reviewed in this section 2.2.1 Conformational Structures of DNA In the elastic regime, DNA behaves as an ideal polymer chain Because DNA consists ... 1997) Among all the forms of DNA, B -DNA is thought to be the dominant form of DNA under physiological conditions Many of biological functions of DNA, such as DNA and RNA polymerase interaction, are...
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PH DEPENDENCE OF THE OPTICAL BIO SENSOR BASED ON DNA SEMICONDUCTOR GRAPHENE NANORIBBONS
... phase transition of DNA is the working principle of this optical biosensor at the sub cellular level from DNA and semiconductor graphene ribbons It is proved that the AGNR -DNA based biosensors ... transition of DNA is the working principle of this optical biosensor at the sub cellular level from DNA and semiconductor graphene ribbons The theoretical model of biosensor based on DNA v SGR has ... of the exciton binding energy (16) pH-DEPENDENCE OF THE OPTICAL BIO-SENSOR 85 IV CONCLUSIONS This new combining structure of DNA and SGR is really interesting The biosensor based on DNA and GNR...
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Tài liệu Báo cáo khóa học: Determination by electrospray mass spectrometry and 1H-NMR spectroscopy of primary structures of variously fucosylated neutral oligosaccharides based on the iso-lacto-N-octaose core doc
... structure/function relationships, particularly in the postgenome era, in order to understand post-translational glycosylation and its function Expansion of our knowledge on the repertoire of carbohydrate structures, ... [23], one tetrafucosyl- ated [24], and one pentafucosylated [24] oligosaccharides Acidic structures described include one monosialyl-monofucosylated [25], two monosialyl-difucosylated [25] and one ... fragmentation The nomenclature used to define the cleavage is based on that introduced previously [15], and ions marked with ÔhÕ are fragments produced by dehydration of the major ions individual monosaccharide...
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Being Born Under Adverse Economic Conditions Leads to a Higher Cardiovascular Mortality Rate Later in Life: Evidence Based on Individuals Born at Different Stages of the Business Cycle pdf
... Cycle* We connect the recent medical and economic literatures on the long-run effects of early-life conditions, by analyzing the effects of economic conditions on the individual cardiovascular (CV) ... socio-economic status as explanations for health later in life.1 In this paper we aim to combine the medical/epidemiological and economic contributions on long-run effects of early-life conditions, ... examining fluctuations in birth rates and twinning rates, and by using additional survey data on the composition Long-run effects of economic conditions early in life may work through nutrition, disease...
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Báo cáo khoa học: Well-defined secondary structures Information-storing molecular duplexes and helical foldamers based on unnatural peptide backbones pot
... oligoamide backbone could fold into well-defined and robust conformation based on backbone rigidification, could the same strategy of backbone rigidification be applied to different unnatural backbones? Initial ... yielded an interior cavity that is electronegative and hydrophilic Once the conformation of the amide backbone was confirmed, the extension of the backbone beyond the length of a single turn, and ... Strong dimerization of ureidopyrimidones via quadruple hydrogen bonding Self-assembly mediated by the donor-donor-acceptoracceptor-acceptor-donor (DDA-AAD) hydrogen-bonding motif: Formation of...
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Báo cáo khoa học: Detection of nucleolar organizer and mitochondrial DNA insertion regions based on the isochore map of Arabidopsis thaliana ppt
... classification, except the mitochondrial DNA insertion isochore in chromosome II, all other regions in A thaliana belong to GC-poor families and most of the variation between two adjacent regions is ... distributions of the purine ⁄ pyrimidine, amino ⁄ keto and weak H-bond ⁄ strong H-bond along the sequence, respectively As mentioned above, zn displays the distribution of bases of GC ⁄ AT types along ... regions located in chromosome II, which show different properties from other regions The first GC-rich region is located in the nucleolar organizer region (NOR) The second region is a mitochondrial...
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Báo cáo hóa học: " A broadly applicable method to characterize large DNA viruses and adenoviruses based on the DNA polymerase gene" doc
... comparisons yet small enough for efficient PCR) There was considerable variation in the deduced amino acid sequences between families Several small regions of conservation were identified Only one ... one region with conservation of at least consecutive amino acids was found among nearly all sequences evaluated This was the YGDTD sequence previously described [1] The only differences among viruses ... positive control (CCV DNA) and – indicates a negative water control, Kb = Kb ladder (Invitrogen), lower case letters indicate extraction protocols with no designation being a total DNA extraction from...
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Báo cáo hóa học: " Research Article Short Exon Detection in DNA Sequences Based on Multifeature Spectral Analysis" potx
... Journal on Advances in Signal Processing Exon1 Intron1 Exon1 Exon2 Exon2 Intron2 Exon3 Exon3 Figure 1: A eukaryotic gene and the splicing process to distinguishing exonic and intronic regions is based ... signal is nonstationary in nature since different regions of the sequence contain different frequency components Many traditional signal processing methods including the DFT are based on the premise ... second evaluation criterion is the rate of correct detection of short exons, each of which is no longer than 70 bp In the simple PSD addition method, we compute the PSD for each of the four DNA...
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Báo cáo hóa học: " Segmentation of DNA into Coding and Noncoding Regions Based on Recursive Entropic Segmentation and Stop-Codon Statistics" ppt
... Stop codons in three phases Figure 1: Distribution of stop codons along three phases in noncoding DNA regions Figure 2: Distribution of stop codons along three phases in coding DNA regions The ... Regions 83 Table 1: Distribution of stop codons along phases for coding and noncoding DNA regions DNA sequence Sequence length [bp] No stop codons [%] one 40 40 80 80 120 120 160 160 Coding Noncoding ... stop codons in DNA coding regions is different than in the noncoding regions Also, it is well known that the stop codons are strong signals in DNA sequences In coding regions, the stop codons are...
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báo cáo khoa học: " Identification of tissue-specific, abiotic stressresponsive gene expression patterns in wine grape (Vitis vinifera L.) based on curation and mining of large-scale EST data sets" docx
... expression values, the time point/condition with the greatest fold-change was used for comparison and probesets with contradictory responses to stress (expression significantly increased in one condition, ... ESTAP Root cDNA library construction A third mixed cDNA library ("VVM”, Library ID 22274) was constructed using total RNA from cold, water-deficit, 150 mM NaCl stressed and control condition roots ... s-1 on a 16-h light (24°C)/8-h dark (18°C) cycle Roots were detached from non-stressed plants and subjected to control conditions (bathed in liquid MS media as above), water deficit stress conditions...
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báo cáo khoa học: " The origin of populations of Arabidopsis thaliana in China, based on the chloroplast DNA sequences" docx
... plant population and evolutionary genetics However, studies focused on global patterns of cpDNA genetic variation among accessions of A thaliana are scattered In an investigation on the maternal ... (2) to infer phylogenetic relationships among A thaliana accessions from all over the world based on cpDNA sequence data, with particular focus on Chinese populations; and (3) to discuss the possible ... information is listed in Table Discrimination of two major differentiated haplotypes among A thaliana accessions When only the parsimony-informative sites were considered, the nucleotide variation...
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Báo cáo y học: " A single dose of DNA vaccine based on conserved H5N1 subtype proteins provides protection against lethal H5N1 challenge in mice pre-exposed to H1N1 influenza virus" ppt
... stimulation with NP peptide; M1: immunization with M1 DNA and stimulation with M1 peptide; C (NP): unimmunization control and stimulation with NP peptide; C (M1): unimmunization control and stimulation ... description: NP + M1 (NP): immunization with NP + M1 DNAs and stimulation with NP peptide; NP + M1 (M1): immunization with NP + M1 DNAs and stimulation with M1 peptide; NP: immunization with NP DNA ... Subgroup (DNA vaccine) Anti-NP Anti-M1 Unexposed to H1N1 NP DNA 12.5 ± 1.0 Not done M1 DNA Not done 10.0 ± 0.81 NP + M1 DNAs 12.5 ± 0.58 10.5 ± 1.29 NP DNA 22.0 ± 0.57a, M1 DNA NP + M1 DNAs Pre-exposed...
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báo cáo khoa học: " Transcriptomic identification of candidate genes involved in sunflower responses to chilling and salt stresses based on cDNA microarray analysis" pps
... complete and are derived from cDNA libraries of plants grown under non-stressed conditions, being defense /stress ESTs under represented In the case of sunflower, functional genomic studies targeting ... in main stress/ defense responses, primary metabolic pathways, gene expression or signal transduction were selected for microarray construction BLAST -based GO term prediction application were ... pooled on one sample prior to probe preparation The reference (control) sample consisted of pooled RNA extracted from sunflower seedlings growing under unaltered environmental greenhouse conditions,...
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Báo cáo y học: "Commentary Arterial hypertension due to fructose ingestion: model based on intermittent osmotic fluid trapping in the small bowel" ppt
... intestinal content dilution This reduction of fluid volume in circulation stimulates aldosterone secretion and increases sodium absorption in colon and reabsorption in kidneys Common fluids in ... bowel, due to stimulation of aldosterone secretion by osmotic loads in the upper digestive tract Osmotic loads of common fluids in our diet Many isotonic "sport" drinks contain low amounts of ... hypotension result [7] Osmotic load in the small bowel as a trigger leading to increased colonic sodium absorption Here proposed model is based on the idea that ingestion of hypertonic fluid transiently...
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Báo cáo y học: "Pressure-dependent stress relaxation in acute respiratory distress syndrome and healthy lungs: an investigation based on a viscoelastic model" pps
... inflation for the multiple regression analysis (Figure 3) [see Additional file 1] This improved parameter estimation compared with the analysis exclusively based on the stress relaxation data ... estimation has been exclusively based on the stress relaxation curves under static zero-flow conditions The purpose of the present study was to investigate non-linear pressure-dependent viscoelastic ... provide a theoretical explanation: the experimental results showed that the quasi-static stress strain relation is non-linear [11,24] On the other hand, stress relaxation dynamics are independent...
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Báo cáo sinh học: "Genetic differentiation of European grayling (Thymallus thymallus) populations in Serbia, based on mitochondrial and nuclear DNA analyses" pot
... the only ones remaining in Serbia today, with native grayling occurring only in three of these (see Introduction, Janković [28]) Mitochondrial DNA sequence analysis Two mtDNA loci, control region ... Phylogenetic analysis of the genus Thymallus (grayling) based on mtDNA control region and ATPase genes, with inferences on control region constraints and broad-scale Eurasian phylogeography Mol ... et al Genetics Selection Evolution 2011, 43:2 http://www.gsejournal.org/content/43/1/2 Page of 11 Figure Phylogeny of mtDNA control region haplotypes NJ phylogram based on the data set of Weiss...
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Báo cáo y học: "E-Predict: a computational strategy for species identification based on observed DNA microarray hybridization patterns" pot
... normalization (Table 1) Similarity scores between the vectors were computed using dot product, Pearson correlation, uncentered Pearson correlation, Spearman rank correlation, or similarity based on Euclidean ... product; ED, similarity based on Euclidean distance; PC, Pearson correlation; SR, Spearman rank correlation; UP, uncentered Pearson correlation) parameters For each combination of parameters, intrafamily ... determination from DNADNA hybridization by using genome fragments and DNA microarrays Appl Environ Microbiol 2001, 67:3677-3682 Eisen MB, Brown PO: DNA arrays for analysis of gene expression Methods...
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Báo cáo sinh học: " A DNA vaccine against tuberculosis based on the 65 kDa heat-shock protein differentially activates human macrophages and dendritic cells" pot
... Figure Activation of adaptive immune response induced by DNA- HSP65 Activation of adaptive immune response induced by DNA- HSP65 (A) Expression of Hsp65 mRNA by monocytes stimulated with DNA vaccine ... important implications for the design of new strategies based on immunotherapies and, consequently, on modulation of immune response in TB 11 12 13 14 15 Authors' contributions Nine researchers ... immune response than the infection itself It is important to mention that the stimulation induced by DNA vector was as effective as DNA vaccine regarding the cytokine production, expression of surface...
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Báo cáo sinh học: " A strategy of tumor treatment in mice with doxorubicin-cyclophosphamide combination based on dendritic cell activation by human double-stranded DNA preparation" doc
... double-stranded DNA (dsDNA) induces both humoral and adaptive immune responses [15,22,23] This induction is provided by the action of dsDNA preparations primarily on professional antigenpresenting ... immunization [48,49] Effect of dsDNA preparation on maturation of spleen and bone marrow DCs in vivo To obtain assurance that dsDNA has an inducer effect on DCs in vivo, a set of experiments was undertaken ... The induction of DC maturation is the necessary condition for antigen Page of 10 presentation on the surface of DCs In the following experiments, we chose dsDNA preparation as a maturation stimulus...
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