structure genomic organization and biosynthesis of mirnas
Genomic organization and functional characterization of a novel cancer associated gene u0 44
Ngày tải lên :
14/09/2015, 21:59
... Profile of Human UO-44 4.2 Establishing a Rat Model for Characterization of UO-44 4.2.1 Genomic Structure of Rat UO-44 4.2.2 Isolation and Cloning of Rat UO-44 Variants 4.2.3 Comparative Genomics of ... and Sequencing of HuUO-44 cDNA 4.1.2 5’ Rapid Amplification of cDNA Ends (RACE) 4.1.3 Cloning of Human UO-44 Variants 4.1.4 Genomic Structure of Human UO-44 gene 4.1.5 Tissue Distribution Profile ... thesis to my dad and mum, Tony and Lisa, without which none of this will be possible ii TABLE OF CONTENTS ACKNOWLEDGEMENTS TABLE OF CONTENTS SUMMARY LIST OF TABLES LIST OF FIGURES LIST OF ABBREVIATIONS...
- 198
- 331
- 0
Báo cáo khoa học: Kinetic characterization, structure modelling studies and crystallization of Trypanosoma brucei enolase docx
Ngày tải lên :
23/03/2014, 21:20
... mixture (50 lL total volume) contained lg of genomic DNA from T brucei stock 427, 100 pmol of each primer, 250 lM of each of the four deoxynucleotides, and U of rTaq DNA polymerase with the corresponding ... with those of the rabbit muscle and S cerevisiae enolase and with the natural enzyme in a cytosolic fraction of T brucei Structure modelling, using available threedimensional enolase structures, ... the concentration of enolase ể FEBS 2003 3208 V Hannaert et al (Eur J Biochem 270) Alignment of sequences and structure modelling of T brucei enolase A sequence alignment of T brucei enolase...
- 9
- 397
- 0
Báo cáo khoa học: Structure, signaling mechanism and regulation of the natriuretic peptide receptor guanylate cyclase pptx
Ngày tải lên :
28/03/2014, 23:20
... Kd of 500 nm In the presence of ANP, ECD dimerization was strongly enhanced (Kd 10 nm) [18] Crystal structures of the ECD with and without ANP We have determined the crystal structures of ... determination of the native structures in the absence of crystal contacts and in solution conditions closer to those of the native environment The three-dimensional reconstructions of the apo-ECD dimer and ... The actual and detailed mechanism of GC activation by ANP, namely the signal transduction mechanism, must await determination of NPRA’s GCD structure and ultimately the structure of full-length...
- 12
- 291
- 0
Báo cáo khoa học: Structure, linkage mapping and expression of the heart-type fatty acid-binding protein gene (fabp3 ) from zebrafish (Danio rerio) pot
Ngày tải lên :
31/03/2014, 07:20
... end of the capped and complete zebrafish fabp3 gene transcripts A major band of approximately 200 bp, and two minor bands of 250 bp and 180 bp, were observed after agarose gel electrophoresis of ... lamprey and catfish, and the aerobic muscle of striped bass More recently, cDNAs have been characterized for an H-FABP from rainbow trout and two distinct isoforms of H-FABP from the ventricle of four ... result of evolutional divergence of transcriptional regulation Materials and methods Growth and maintenance of zebrafish adults and embryos Zebrafish were purchased from a local aquarium store and...
- 12
- 505
- 0
Báo cáo khoa học: Purification, characterization and biosynthesis of parabutoxin 3, a component of Parabuthus transvaalicus venom pptx
Ngày tải lên :
31/03/2014, 09:20
... mass of the compounds in the venom and the masses of rAgTx2 (used as a control toxin) and rPBTx3 were determined with MALDI-TOF MS on a VG Tofspec (Micromass, UK) operating in the linear and in ... disulfide pairing [44] and is also conserved throughout these sequences of all the members of subfamily of a-KTx, including PBTx3 Because of these similarities and conservation of the consensus sequence, ... inhibition of Kv1.1 channels of 50%, whereas 550 nM native PBTx3 produces 54% and 51% block of the Kv1.2 and Kv1.3 channels, respectively (Fig 4A–C) We have undertaken the recombinant synthesis of this...
- 12
- 502
- 0
Management ownership structure, audit quality and impairment of assets--evidence from China
Ngày tải lên :
01/06/2014, 14:02
... words, the demand for financial reporting by the public and the government's participation in setting and enforcing rules and standards affect the ownership structure of enterprises and in turn ... academic professionals, Professor Ferdinand Gul, Professor Jeong Bong Kim, Professor Bin Srinidi, Professor T.J Wong, Dr Shimin Chen, Dr Peter Cheng, Dr Agnes Lo, Dr Raymond Wong, Dr Xiaodong Xu and ... decision of writing down the value of assets and the magnitude of write-down allow management of listed companies to exercise discretion in determining the recoverable value of relevant assets and...
- 259
- 335
- 0
Opal''''s Site Organization and Development of Russian Business_1 docx
Ngày tải lên :
20/06/2014, 20:20
... analysis of probability to obtain financial and organizational support from the state authorities Utility of business associations and their contribution to the establishment of standards and rules of ... impacts of business integration via the formation of holding companies and other types of business groups upon corporate governance and firm performance of affiliated firms; and (c) the role and ... boards of directors, and its chairs in 2001–2004 Comparison of JSCs with separation or combination of ownership and management Logistic regressions for shareholder choice of separated ownership and...
- 23
- 266
- 0
Opal''''s Site Organization and Development of Russian Business_2 pptx
Ngày tải lên :
20/06/2014, 20:20
... by studies of economic transition and company behavior in transition economies, with the participation of leading economists of the world, including Andrei Shleifer, Gerard Roland, and Josef Stiglitz ... were related to the compilation and approval of five-year plans and implementation of investment projects came within the competence of higher levels of government); and (c) managers were involved ... planned target volumes and resources allocated to the enterprise and with suppliers and customers on product mix and other terms of supply This pattern of behavior was typical of enterprises in all...
- 23
- 286
- 0
Opal''''s Site Organization and Development of Russian Business_3 pdf
Ngày tải lên :
20/06/2014, 20:20
... in lack of capacity, lower wages and profitability, and a higher risk of loss Moreover, the authors produced evidence (in a small sample of companies) of the positive role of the size of shareholding ... loans, and funds of Russian partners and other private investors A comparison of ownership structures and intensity of corporate restructuring performed by the Bureau of Economic Analysis as part of ... PM 42 Organization and Development of Russian Business Less than 25% of shares 13% More than 50% of shares + absence of a counterbalance 48% From 25% to 50% of shares 18% More than 50% of shares...
- 23
- 344
- 0
Opal''''s Site Organization and Development of Russian Business_4 ppt
Ngày tải lên :
20/06/2014, 20:20
... indicators of performance and intensity of restructuring At the average level of concentration, these companies would clearly take the lead in terms of better performance and the introduction of new ... free of charge and the shares of state-owned and municipal enterprises On the other hand, in consideration of the fact that managers are still the dominant shareholders in many Russian firms and ... part of the new managers may also contribute This mechanism of control is well studied: a series of works were dedicated to the analysis of change of managers, especially due to ineffectiveness of...
- 23
- 367
- 0
Opal''''s Site Organization and Development of Russian Business_5 potx
Ngày tải lên :
20/06/2014, 20:20
... choice of organizational form in gasoline retailing and the cost of laws that limit that choice, Journal of Law and Economics, 44: 511–524 Brickley, J A & Dark, F H (1987) The choice of organizational ... effect of state involvement is much stronger than the influence of private owners The impact of capital demand and the development of local financial institutions also reduce the probability of the ... open-end: The choice of organizational form, Journal of Corporate Finance, 8: 1–27 Denning, K & Shastri, K (1993) Changes in organizational structure and shareholder wealth: The case of limited partnership,...
- 23
- 291
- 0
Opal''''s Site Organization and Development of Russian Business_6 pptx
Ngày tải lên :
20/06/2014, 20:20
... Determinants of the size and structure of corporate boards: 1935–2000 Unpublished working paper, University of Pittsburgh Li, J (1994) Ownership structure and board composition: A multi-country test of ... governance and the board of directors: Performance effects of changes in board composition, Journal of Law and Economics, 1: 101–124 Baysinger, B & Hoskisson, R E (1990) The composition of boards of ... theories and empirical methods 9780230_217287_06_cha04 dd 114 5/14/2009 3:46:37 PM The Structure of Corporate Boards 115 of financial and organizational economics help pinpoint the determinants of...
- 23
- 342
- 0
Opal''''s Site Organization and Development of Russian Business_7 ppt
Ngày tải lên :
20/06/2014, 20:20
... vote-counting analysis of the impact of different types of owners and changes in ownership structure on CEO turnover Corporate Governance and Managerial Turnover 129 study, only 19.5% of all 113 CEOs ... argue that, because of the national culture of social collectivism, the 70-year-long history of the riskaverse way of life in the Soviet period, and the Continental European nature of corporate law, ... management of that company to offset the loss of the top manager’s firmspecific knowledge and experience This is particularly true of dominant shareholders, mainly Russian oligarchs and business...
- 23
- 308
- 0
Opal''''s Site Organization and Development of Russian Business_9 ppt
Ngày tải lên :
20/06/2014, 20:20
... 188 Organization and Development of Russian Business total of 456 of surveyed JSCs, 38% of companies had separate ownership and management compared to less than 28% of independent businesses and ... technologies, and certification of production in line with international standards, which are measures of a more profound reform of the business Therefore, we used the existence of (both severe and moderate) ... respondents of the role of main bodies in corporate decision-making, composition of the board of directors, relations between actors of corporate governance (Table 7.2), and intensity of rotation of corporate...
- 23
- 305
- 0
Opal''''s Site Organization and Development of Russian Business_10 pptx
Ngày tải lên :
20/06/2014, 20:20
... impact of BG membership on the performance of subsidiaries, and the analysis will provide evidence in favor of H5 Organization of Russian business groups The ratio of enterprises that are members of ... the size of the companies and by the specifics of regulated industries First, the importance of stakeholders and the scale of networking generally increase with the size of the company and the ... governance of transactions and not a network of enterprises that are equal partners Moreover, with the course of time, Russian BGs restructured the system of decision-making toward further separation of...
- 23
- 289
- 0
Opal''''s Site Organization and Development of Russian Business_12 pot
Ngày tải lên :
20/06/2014, 20:20
... growth rates of sales between 2000 and 2004, rates of wage increase during the same period, rates of increase in the number of employees between 2001 and 2005, and the prevailing economic and financial ... times, and for over times); Rate of increase of employees between 2001–2005 (Ϫ2 for decrease over 20%, Ϫ1 for decrease of 1–19%, for no change, for increase of 1–19%, and for increase of 20% and ... chapter is the result of a study with financial assistance from the Ministry of Education and Science of Japan (Nos 16530149, 17203019, and 17730157) and from the Foundation of Japan Legislation...
- 23
- 255
- 0
Opal''''s Site Organization and Development of Russian Business_13 pdf
Ngày tải lên :
20/06/2014, 20:20
... 5:38:14 PM 276 Organization and Development of Russian Business Table 11.7 Utility of business associations and their contribution to the establishment of standards and rules of conduct of business, ... Significance of differencesa Table 11.1 Characteristics of companies: Members and nonmembers of business associations (percentage of respondents who answered) 264 Organization and Development of Russian ... authorities and receive organizational support from them were found among members of associations, which is a confirmation of the hypothesis involving an exchange of elites and a proof of the conclusions...
- 23
- 259
- 0
Opal''''s Site Organization and Development of Russian Business_14 docx
Ngày tải lên :
20/06/2014, 20:20
... Relations and Corporate Governance 287 effect by the results of such measures as toughening of budget constraints and bank lending policies, stronger competition of imports, and introduction of a ... stake being in the hands of a single shareholder; the financial conditions of the firm; the presence of foreign shareholders; and the previous job experience of top-managers of surveyed firms in ... mechanisms and procedures of corporate governance for the defense of its interests The government used the regulation of entry and tariffs as an additional channel of influence on the behavior of enterprises,...
- 23
- 289
- 0
Opal''''s Site Organization and Development of Russian Business_15 pdf
Ngày tải lên :
20/06/2014, 20:20
... sector and industry, form of incorporation, and total number of employees To sum up, our sample is representative of large- and medium-scale JSCs in Russia and fits the research objectives of this ... interests and behavior of strategic and portfolio investors, minority shareholders, banks and pension funds, and participants of securities markets, including auditors, stock exchanges, and brokerages, ... impediment to competition and an obstacle to evolution of the private sector? How capable will the state be of dividing the functions of a proprietor from the functions of a regulator and arbitrator, including...
- 20
- 350
- 0
Organization and Development of Russian Business A Firm-Level Analysis_1 potx
Ngày tải lên :
20/06/2014, 23:20
... by studies of economic transition and company behavior in transition economies, with the participation of leading economists of the world, including Andrei Shleifer, Gerard Roland, and Josef Stiglitz ... were related to the compilation and approval of five-year plans and implementation of investment projects came within the competence of higher levels of government); and (c) managers were involved ... planned target volumes and resources allocated to the enterprise and with suppliers and customers on product mix and other terms of supply This pattern of behavior was typical of enterprises in all...
- 23
- 335
- 0