structure and biological activities of glycosaminoglycan analogs from marine invertebrates new therapeutic agents
Tài liệu Báo cáo khoa học: Design, structure and biological activity of b-turn peptides of CD2 protein for inhibition of T-cell adhesion ppt
Ngày tải lên :
19/02/2014, 13:20
... N- and C-termini A comparison of the b-turn structure of cER with the similar region in the crystal structure of rat and human CD2 was carried out In the rat CD2 crystal structure, the b-turn structure ... bonds between NH of Thr5 and CO of Arg2, as well as NH of Arg2 and CO of Thr5 Structure of cyclic hexapeptides – cYT peptide The NMR data of the cYT peptide were indicative of its flexible nature ... lines of evidence suggest that peptides from rat CD2 may bind to human CD58 Human-CD2 and rat-CD2 have high 3D structure similarity Comparison of 3D structures of hCD2 from CD2–CD58 complex [30] and...
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Tài liệu Báo cáo khoa học: The structure and biological characteristics of the Spirochaeta aurantia outer membrane glycolipid LGLB pdf
Ngày tải lên :
19/02/2014, 16:20
... Fragments of HSQC and HMBC spectra of compound Labels illustrate assignment of the amide linkage between the amino group of Asp and the carboxyl group of GalA residue E Scheme The structures of oligosaccharides ... result from the loss of Q from I-D-N-Q (m/z 648.20) or from the loss of F from F-I-D-N (m/z 732.18) However, many other combinations of fragments are also possible, because of the existence of branches ... present in the products and were identified, and the ratio of structures and was close to : All chemical shifts remained mostly unchanged with the exception of H/C-2 and H/C-3 of the glycerol residue...
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Tài liệu Báo cáo khoa học: Physicochemical characterization and biological activity of a glycoglycerolipid from Mycoplasma fermentans ppt
Ngày tải lên :
21/02/2014, 00:20
... fluorescence intensity as function of time of doublelabeled liposomes made from PS (A) or from PC (B) after the addition of MfGl-II or LPS Re at t = 50 s and subsequent addition of LBP (0.2 mM) at t = 100 ... behavior of the acyl chains was derived from the peak position of the symmetric stretching vibration of the methylene groups ms (CH2), which lies around 2850 cm)1 in the gel and between 2852 cm)1 and ... Biophysical study of Mycoplasma glycolipid (Eur J Biochem 270) 3273 Aggregate structures and molecular shape For the determination of the three-dimensional supramolecular structure of the lipid aggregates,...
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Báo cáo Y học: Synthesis, conformational analysis and biological activity of cyclic analogs of the octadecaneuropeptide ODN Design of a potent endozepine antagonist pot
Ngày tải lên :
24/03/2014, 04:21
... analysis of the calculated structures revealed a short distances between NH of Leu7 and the side chain carboxyl group of the Asp6 residue (< 0.28 nm), and NH of Leu7 residue and C¼O of Leu5 (< ... Analysis of hydrogen bonds and dihedral angles (F, C) for the average structures generated from members of cis and trans family of cyclo128 [D -Leu5]OP showed that the residues of the cis and trans ... resulting from cis/trans isomerism Characterization of the secondary structure of these two ligands of ODN receptors should provide useful information for the design of potent, stable and selective...
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Study on chemical constituents and biological activities of some plants of boerhaavia genus (nyctaginaceae)
Ngày tải lên :
24/08/2015, 12:40
... 3.1.4 Chemical structure of flavonoids 68 3.1.5 Chemical structure of nitrogen compounds 78 3.1.6 Chemical structure of phenolic compounds 83 3.1.7 Chemical structure of steroids and terpenoids ... OA of the mixed solution (*) with replacement 25µl of buffer B, instead of 25µl of samples OA2: the OA of the mixed solution (*) with replacement 50µl of buffer B, instead of 25µl of samples and ... compounds, two news and ten knowns) Group G: Terpenoid and steroid (six compounds, one news and five knowns) Group H: Others (six compounds, three news and three knowns) 3.1.1 CHEMICAL STRUCTURE OF 12a-HYDROXYROTENOIDS...
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Study on chemical constituents and biological activities of the lichen parmotrema Praesorediosum(NYL ) hale(parmeliaceaf)
Ngày tải lên :
15/12/2015, 15:22
... elucidation of compound PRAES-C3 89 3.1.5.7 Structure elucidation of compound PRAES-C4 91 3.1.5.8 Structure elucidation of compound PRAES-C21 93 3.1.6 Chemical structure of dibenzofurans ... IR, MS and NMR spectra of PRAES-C1 146 Appendices 8-15: IR, MS and NMR spectra of PRAES-E14 149 Appendices 16-21: MS and NMR spectra of PRAES-C10 153 Appendices 22-26: MS and NMR spectra of PRAES-C11 ... activity of methanol extract of P pseudotinctorum from the Western Ghats of Karnataka Sinha and Biswas [69] reported the antibacterial efficacy of solvent extracts of P reticulatum from Sikkim,...
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STUDY ON CHEMICAL COMPOSITIONS AND BIOLOGICAL ACTIVITIES OF annona glabra l
Ngày tải lên :
28/04/2016, 17:48
... compositions and biological activities of Annona glabra L So, the thesis’s title was proposed to be "Study on chemical compositions and biological activities of Annona glabra L." Subject and contents of ... completed at: Institute of Marine Biochemistry Vietnam Academy of Science and Technology Advisors: Prof Dr Phan Van Kiem Institute of Marine Biochemistry - Vietnam Academy of Science and Technology Dr ... Subject is the leaves and fruits of Annona glabra - The aims of the thesis: Extraction and isolation of secondary metabolites from A glabra; Determination of chemical structure of the isolated compounds;...
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Structure and mechanism studies of sugar epimerase from dictyoglomus turgidum
Ngày tải lên :
20/05/2016, 21:08
... Figure3.3Crystals of Apo-CYP107W1 and Oligomycin A-CYP107W1 72 Figure3.4Ramachandran plot of ϕ and ψ dihedral angles of Apo-CYP107W1 74 Figure3.5Overall structure of Apo-CYP107W1 77 Figure3. 6Structure- based ... Figure1.10Crystals of His-tagged and untagged Epi_DT 28 Figure1.11Diffraction images of His-tagged (a) and untagged (b) Epi_DT .30 Figure1.12Ramachandran plot of ϕ and ψ dihedral angles of Epi_DT ... 1.17Surface map of catalytic center in Apo and lactose-Epi_DT structure 41 Figure1.18Overall structure of Epi_DT with its ligand 43 Figure1.19Interactions between ligand and important residues...
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Effect of secondary structure on biological activities of antimicrobial peptides
Ngày tải lên :
24/10/2016, 11:20
... silica cell and its ellipticity was scanned from 190 to 250 nm at a sensitivity of 100 millidegrees, response time of 1s, bandwidth of nm, and a scan speed of 100nm/min The values of molar ellipticities ... the importance of a lack of structure in nondenaturing conditions but an inducible structure in the presence of the hydrophobic environment of the membrane, (ii) the presence of a positively ... level of activity against various gram-negative and gram-positive bacteria and, more importantly, negligible hemolytic activity Materials and methods Peptide synthesis and purification Synthesis of...
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Báo cáo khoa học: Role of different moieties from the lipooligosaccharide molecule in biological activities of the Moraxella catarrhalis outer membrane pot
Ngày tải lên :
07/03/2014, 05:20
... OS and consisted of a linker (Glc-Kdo2)-lipid A structure The phenotype of this mutant was examined to investigate the roles of different moieties of the LOS molecule in biological activities of ... unit consists of two GlcNAc and two 3-OH C12:0 groups Among the other ions m ⁄ z of 2654.8, 2694.8 and 2717.4 indicates the presence of the anhydro form and mono- and di-sodiated form of the molecular ... lipid-A and two phosphate moieties The ions with m ⁄ z of 1519.6 and 1541.6 are mono- and di-sodiated forms of the de-O-acylated LOS and the ion with m ⁄ z of 1479.6 is the anhydrous form of the...
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Báo cáo khoa học: Crystal structure and enzymatic properties of a bacterial family 19 chitinase reveal differences from plant enzymes pdf
Ngày tải lên :
07/03/2014, 11:20
... shows that the first reaction equally often results from cleavage between sugars and (new reducing end on the tetramer product) as from cleavage between sugars and (new reducing end on the dimer product) ... amounts of (GlcNAc)3 and (GlcNAc)2; the 80 : 20 anomeric ratio of the products indicates that cleavage after sugar or sugar occurs approximately equally often Structure The overall structure of ChiG ... similar to that of the family 19 chitinase from barley, the best studied of the plant chitinases [9,12,13,27,28] and essentially identical to that of the catalytic domain of ChiC from S griseus...
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PREDICTION OF CHEMICAL REACTIVITY PARAMETERS AND PHYSICAL PROPERTIES OF ORGANIC COMPOUNDS FROM MOLECULAR STRUCTURE USING SPARC pptx
Ngày tải lên :
22/03/2014, 14:20
... chemical and physical properties to Program Offices (e.g., Office of Water, Office of Solid Waste and Emergency Response, Office of Prevention, Pesticides and Toxic Substances) and Regional Offices ... databases The strength of the electrostatic interaction between S and C depends on the magnitude and relative orientation of the local fields of S and C and the dielectric properties and distances through ... induction, resonance and field effects SPARC execution involves the classification of molecular structure (relative to a particular reactivity of interest) and the selection and execution of appropriate...
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Báo cáo khoa học: H NMR study of the molecular structure and magnetic properties of the active site for the cyanomet complex of O2-avid hemoglobin from the trematode Paramphistomum epiclitum pdf
Ngày tải lên :
23/03/2014, 17:22
... Tyr66(E7) (G) and Leu70(E11) (E), and to NHs of heme-residue contacts Tyr66(E7) and Phe46(CD1) to have propionates (A, B, C) and interresidue contacts from Tyr66(E7) to Phe46(CD1) and NHs of Arg48(CD3) ... shifts of an unfolded tetrapeptide relative to DSS [45], the effect of secondary Fig Schematic representation of the heme pocket of Pe Hb as found in the crystal structure of Pe metHbH2O [16] and ... of Pe metMbCN Proximal and distal residues are shown as rectangles and circles, respectively, and arrows connecting heme substituents and residues, and between residues, reect NMR observed, and...
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Báo cáo " Isomeranzin against Herpes simplex virus in vitro from Clausena heptaphylla (Roxb.) W. & ARN.: Isolation, structure and biological assay " potx
Ngày tải lên :
03/04/2014, 15:20
... high yield (0.7 ÷ 0.8%) The structure of the compound was determined by interpretation of its spectral data (IR, MS, 1H and 13C-NMR) and by comparison with spectral data of an authentic sample The ... collected from the Ba Vi Forerst, Northern Vietnam many times The plant was determined by Botanist, Dr Tran Ngoc Ninh, Vietnamese Academy of Science and Technology Extraction and isolation Leaves of ... acetate plus virus), examining the effectiveness of a water extract of the plant, or elucidating the mechanism of synergistic cytotoxicity of ethanol and the compound It is possible that the compound...
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báo cáo hóa học: " Factor structure and internal consistency of the 12-item General Health Questionnaire (GHQ-12) and the Subjective Vitality Scale (VS), and the relationship between them: a study from France" potx
Ngày tải lên :
18/06/2014, 19:20
... Goodness of Fit Index = 0.93, Adjusted Goodness of Fit Index = 0.90, Root Mean Square Error of Approximation (RMSEA) = 0.03, and χ2/df = 2.26 (Table and Figure 1) In summary, the two and three ... values of 0.80 and 0.89 Page of (page number not for citation purposes) Health and Quality of Life Outcomes 2009, 7:22 http://www.hqlo.com/content/7/1/22 Table 2: Descriptive statistics and correlations ... reliability and factor structure of the Subjective Vitality Scale (VS) in France The results show that it has good psychometric properties in terms of internal consistency and factor structure...
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Crystal structure, optical properties and biological imaging of two curcumin derivatives
Ngày tải lên :
01/07/2014, 13:22
... later The structures of A and B are shown in Fig 2, which revealed that the molecular structures of A and B are similar and also symmetric to our satisfaction Selected bond lengths ( and bond ... cross-section values of s of the compounds A and B are 386 and 418 GM (1 GM ¼ 10À50 cm4 s photonÀ1 moleculeÀ1) in DMF solution, respectively 3.4 Cytotoxicity assay and biological images of two-photon ... 0.1701 1.028 Gof on F2 314 G Xu et al / Dyes and Pigments 101 (2014) 312e317 Fig Molecular structure of A and B showing 50% probability displacement 3.2 Linear absorption spectra and single-photon...
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Báo cáo toán học: "Structure and fractal dimensions of root systems of four co-occurring fruit tree species from Botswana" doc
Ngày tải lên :
08/08/2014, 14:22
... of Strychnos spinosa with a weak age dependence of the number of terminal roots and of total root length (R2 = 0.24, resp 0.34), and with the exception of both Strychnos species in the case of ... grid resolution of m, which falls just under the order of magnitude of the overall root system extension, and a highest resolution of 15 cm, which lies in the order of magnitude of the mean interbranching ... well-defined for the structure under consideration, it serves as a measure of occupation of space at different length scales and as an indicator of certain forms of self-similarity (see [14] and [16] for...
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Báo cáo sinh học: "Correlation between antibutyrylcholinesterasic and antioxidant activities of three aqueous extracts from Tunisian Rhus pentaphyll" potx
Ngày tải lên :
12/08/2014, 17:20
... presence of tannins and flavonoids by using the methods previously described by Mansour et al [20] Two Page of milligrams of each extract were dissolved in ml of water The identification of major ... employed: 1.5 ml of phosphate buffer 50 mM pH = 7.2, containing 0.26 mM of 5,5’-dithiobis-2- nitrobenzoic acid (DTNB), 10 μl of human plasma and 10 μl of the tested compound (1, 10 and 100 μg/ml ... (in μg/ml) of substrate that causes 50% loss of DPPH activity (color) and it was calculated by using the Litchfield and Wilcoxon test [20] The results are expressed as the mean of data from at least...
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Synthesis and biological evaluation of natural products and their analogs as new cancer chemotherapeutic agents
Ngày tải lên :
10/09/2015, 15:49
... SYNTHESIS AND BIOLOGICAL EVALUATION OF NATURAL PRODUCTS AND THEIR ANALOGS AS NEW CANCER CHEMOTHERAPEUTIC AGENTS FANG ZHANXIONG (B.Sc.(Hons.) NUS) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... 3.6 Structure of itaconic acid 3-13a, its dimethyl derivative 3-13b and ligands used for asymmetric hydrogenation 120 vii Figure 4.1 Structures of (S)-monastrol and its analogs as inhibitors of ... synthesis of analogs of pepticinnamin and curacin A.75,76 Today the synthesis of a library of compounds based on a natural product scaffold is commonplace for the optimization of the biological and...
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