structural role of collagen imbalance in collagen remodeling
Báo cáo y học: "Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes"
... ANK3 Gene title cofactor of BRCA1 integrin, beta staufen, RNA binding protein, homolog (Drosophila) high mobility group nucleosomal binding domain ankyrin 3, node of Ranvier (ankyrin G) Signal Log ... NM_014393 ▲ 1.52 regulation of transcription protein binding double-stranded RNA binding DNA binding ▼ 5.02 protein binding NM_001149 NM_004242 ▲- increased ▼- decreased Validation of microarray results ... ethanol-induced mucosal injury in the upper gastrointestinal tract leading to increase in the permeability of the gut mucosa to endotoxins [43, 44] These factors are involved in ethanol-induced...
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The role of leadership theory in raising the profile of women in management
... viewed as limited in raising the profile of women in management However, during this period of research, there was an emerging recognition of the importance of a concern for people in the behavioural ... more typical of male behaviours Of interest is the inclusion of ‘‘control’’ as a significant feature of the transactional style, common in definition of leadership in the 1990s In contrast, women ... superiority in utilising effective leadership styles of interaction with their subordinates and organisational outcomes, actually translates into a dramatic increase in the numbers of women being appointed...
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Globalization: the Role of Institution Building in the Financial Sector _ The Case Study of China
... The role of FDI in institution building Over the past 20 years, foreign financial institutions, mainly foreign banks have played an important role in the opening up of Chinese financial industry ... technology, in exploring on-line banking business as well as in promoting non-bank financial institutions Efforts should be made in upgrading financial operations and financial services, and in conducting ... China Statistics Yearbook, China Financial Yearbook and People’s Bank of China Statistics Quarterly bulletin B Development of direct financing and indirect financing markets providing financing...
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Tài liệu Báo cáo khoa học: Role of Kupffer cells in pathogenesis of sepsis-induced drug metabolizing dysfunction pptx
... shown that interactions between KCs and endotoxin comprise the initiating event leading to hepatotoxicity in liver injury, including endotoxemia and ischemia ⁄ reperfusion injury [14] In our studies, ... receptor signaling is independent of Toll-interleukin receptor domain-containing adaptor protein Drug Metab Dispos 36, 95–101 10 Ghose R, Guo T & Haque N (2009) Regulation of gene expression of hepatic ... MA, USA) Binding of all of the antibodies was detected using an ECL detection system (iNtRON Biotechnology, Seoul, Korea) in accordance with the manufacturer’s instructions The intensity of the...
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Tài liệu The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States: A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory Committee on Immunization Practices docx
... boosted by administering a tuberculin skin test week to year after the initial postvaccination skin test; ongoing periodic skin testing also might prolong reactivity to tuberculin in vaccinated persons ... preventing pulmonary TB in adolescents and adults These studies also were not useful in determining a) the efficacy of BCG vaccine in HCWs or b) the effects on efficacy of the vaccine strain administered ... Tuberculin Skin Testing and Interpretation of Results After BCG Vaccination Postvaccination BCG-induced tuberculin reactivity ranges from no induration to an induration of 19 mm at the skin-test site...
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Tài liệu Rethinking the Role of the State in Finance doc
... Rethinking the Role of the State in Finance Global Financial Development Report 2013 Rethinking the Role of the State in Finance Washington, D.C © 2012 International Bank for ... important role, especially in providing supervision, ensuring healthy competition, and strengthening financial infrastructure Incentives are crucial in the financial sector The main challenge of financial ... possible countercyclical role of state-owned financial institutions, and the role of the state in promoting information sharing—all topics that are examined in the current Global Financial Development...
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Tài liệu The Role of Community Banks in the U.S. Economy pdf
... them to maintain higher net interest margins Indeed, during most of the 1990s, the net interest margin of small banks held steady at over 4.5 percent, while the net interest margin of large banks ... key role serving certain types of communities and providing certain types of banking services ECONOMIC REVIEW • SECOND QUARTER 2003 17 Definition of a community bank There is no single definition ... Banking Industry,” Journal of Banking and Finance, August Sullivan, Richard J 2000 “How Has the Adoption of Internet Banking Affected Performance and Risk in Banks? A Look at Internet Banking in...
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Tài liệu SICK WATER? THE CENTRAL ROLE OF WASTEWATER MANAGEMENT IN SUSTAINABLE DEVELOPMENT pdf
... Depending on the type of ore deposit being mined, tailings can also contain heavy metals like copper, lead, zinc, mercury and arsenic The contaminants in mine waste may be Cooling waters used in industrial ... Figure 19 in the timing and intensity of rainfall, or the period of time without rain, as well as affecting the quality of water in rivers and lakes through changes in the timing and volume of peak ... filtration, and increases the groundwater contamination 38 Figure 13: Mining effects on rainfall drainage Acid Mine Drainage (AMD) is the number one environmental problem facing the mining industry...
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Tài liệu Báo cáo khoa học: A role of miR-27 in the regulation of adipogenesis ppt
... or without hematoxylin staining In hypoxia experiments, 3T3-L1 cells were maintained in a hypoxia chamber (Invivo 400; Ruskinn Inc., Cincinnati, OH, USA) constantly maintained at 1% O2 Culture ... initiated at 48 h post-transfection by maintaining the cells in culture medium containing 2% horse serum Cells were fixed on day of differentiation and stained with hematoxylin and eosin One of ... DMEM containing 10% fetal bovine serum OP9 cells were grown in aMEM containing 20% fetal bovine serum C2C12 cells were maintained in DMEM containing 10% fetal bovine serum Adipogenic differentiation...
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Tài liệu Báo cáo khoa học: Emerging pathways in genetic Parkinson’s disease: Potential role of ceramide metabolism in Lewy body disease pptx
... phospholipase A2 participates in ER stress-induced INS-1 insulinoma cell apoptosis by promoting ceramide generation via hydrolysis of sphingomyelins by neutral sphingomyelinase Biochemistry 46, 10170– ... should have a key role in our understanding of the mechanisms of the disease We propose that pathology data will, in most cases, be more insightful than clinical data in defining the disease This ... transport of cholesterol to post-lysosomal destinations Cells from NPC subjects show a decrease in acid sphingomyelinase activity, leading to the accumulation of sphingomyelin [27] Because one of the...
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Tài liệu Báo cáo khoa học: Role of ceramide kinase in peroxisome proliferatoractivated receptor beta-induced cell survival of mouse keratinocytes ppt
... 3821 Role of CerK in PPARb-induced keratinocyte survival K Tsuji et al Fig Schematic model illustrating the role of CerK in cell survival mediated by PPARb in mouse keratinocytes Under injury ... keratinocytes [14] 3816 In this study, we examined the interaction between CerK and PPARb, and its role in regulating keratinocyte survival We report that in a mouse keratinocyte cell line upregulation ... important role in keratinocyte survival during skin wound healing, and PPARb expression is elevated at injury sites [10,15] We investigated whether skin barrier disruption by tape-stripping would induce...
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Tài liệu Báo cáo khoa học: The role of electrostatic interactions in the antitumor activity of dimeric RNases docx
... Electrostatic interactions and antitumor RNases the dimer interface of the models or in the surroundings of the hinge loop residues Likewise, the models of nonexchanging and exchanging HHP-RNase ... trafficking, specifically associate to negatively charged membranes As all these data are suggestive of a role of membranes, in particular of negatively charged membranes, in the mechanism of action of ... values of EIE were recorded at 30° intervals of r from to 360°; (d) the inclination of the dimer major axis with respect to the z axis, hence to the membrane plane, was changed (by inclination of...
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Tài liệu Báo cáo khoa học: Structural characterization of Ca2+/CaM in complex with the phosphorylase kinase PhK5 peptide pdf
... PhK5 might bind with Trp357 in the N-terminal site in CaM, or perhaps could bind in the opposite orientation to incorporate the Trp into the larger C-terminal domain binding site In summary, ... Kay LE, Krinks M & Bax A (1991) Tripleresonance multidimensional NMR study of calmodulin complexed with the binding domain of skeletal muscle myosin light-chain kinase: indication of a conformational ... (1992) High and intermediate affinity calmodulin binding domains of the alpha and beta subunits of phosphorylase kinase and their potential role in phosphorylation-dependent activation of the holoenzyme...
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Tài liệu Báo cáo khoa học: The role of N-glycosylation in the stability, trafficking and GABA-uptake of GABA-transporter 1 Terminal N-glycans facilitate efficient GABA-uptake activity of the GABA transporter pptx
... substrate binding process This provides strong evidence that N-glycans, in particular their terminal structures, are involved in regulating the GABA translocation of GAT1, but not in binding of GAT1 ... terminal structures of the N-glycans of GAT1, N-glycosylation processing of NNN was inhibited by 1-deoxymannojirimycin (dMM) Inhibition by dMM leads to the formation of NNN molecules containing ... misfolding of this protein, resulting in its partial retention in the ER and its rapid digestion thereafter [16,19] Accordingly, our results indicate that the intracellular trafficking of N-glycosylation...
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Tài liệu Báo cáo khoa học: "From HOPE en I''''ESPERANCE On the Role of Computational Neurolinguistics in Cross-Language Studies " pptx
... results Because of the parallel activation of a l l meanings of each recognized word in HOPE, the determination of the phonetic representation of a recognized word determines the breadth of active ... often generic and mark masculine, feminine, or plural (Gross, 1977; Goffic and McBride, 1975) And furthermore, these same articles often are not translated into meaning preserving sentences in ... appropriate masculine/feminine indicators (Jayez, 1982) The issues are not whether human brains work in a universal fashion, but instead raise questions of how interpreted levels of representation,...
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The Role of the Media in Promoting and Reducing Tobacco Use doc
... Bioethics Institute The Johns Hopkins University Washington, DC Monograph 19 The Role of the Media Pamela Ling, M.D, M.P.H Assistant Professor in Residence Department of Medicine, General Internal ... use,12,13 underscoring the urgency of examining the media’s role in global tobacco marketing At the same time, the media have an equally powerful role in influencing individuals and policymakers and ... combining sponsorship, brand merchandising, brand stretching, packaging, point -of- sale promotions, and product placement, across a broad range of channels ranging from event marketing to the Internet.22,23...
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Enterprise Adjustment and the Role of Bank Credit in Russia: Evidence from a 420 Firm''''s Qualitative Survey pdf
... remaining 11% An increase in indebtedness (of 80% in average) is associated with a 14% decrease in production, and with a 2% rise in inventories Conversely, enterprises with a decrease level of indebtedness ... equal to ô ằ (increase in indebtedness) by 15 points (33 minus 18), and increases the probability of Expected-Debt to be equal to ô ằ (not indebted and not going to be) by 13 points (34 minus 21) ... markets - demand-side constraints for most of them and access-to-input for the worst in this sub-pool Conversely, the overbearing influence of the financial constraints in the lower half is statistically...
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BEYOND MICROCREDIT: THE ROLE OF SAVINGS BANKS IN MICROFINANCE potx
... briefly examining the basic characteristics of WSBI member involvement in microfinance in Latin America, Africa, and Asia/the Pacific 1.5.1 Latin America In Latin America, microfinance has experienced ... scale, and outreach continues to grow in terms of the number of microborrowers Institutions providing microfinance in Asia play a critical role in increasing the access to finance for underprivileged ... Microfinance Services by Savings Banks in Africa – The Sleeping Giants have started moving, but where are they going? 2.1 Summary 2.2 Main characteristics of microfinance in Africa 2.3 Savings...
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THE ROLE OF MUSIC COMMUNICATION IN CINEMA potx
... imagery of an individual, even in the absence of an accompanying film Instead, music appears to exert a direct influence on the cognitive processing of a film by guiding selective attending toward ... score, in its typical role, serves to reinforce, alter, and/or augment the emotional content of a cinematic narrative In the following paragraphs, we will propose an extended set of ways in which ... the meaning of the visual image, the more influence is exerted by the musical score in the process of interpreting the scene Music can convey the scope of a film, effectively communicating whether...
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Báo cáo khóa học: Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase docx
... of the )1 sugar ring into a 4-sofa conformation is an inherent part of the catalytic mechanism (Fig [17,19,21,22]) Structural studies show that Asp142, Tyr214 and Asp215 are involved in binding ... mechanistic roles of several of these residues are not described well and there is no example of mutational analysis of all of these residues in the same enzyme To obtain an insight into how the ... formation of the oxazolinium ion intermediate; (C) Hydrolysis of the oxazolinium ion intermediate Copyright National Academy of Sciences, USA questioned on the basis of studies of chitinase A from...
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