stress phagocyte function and microbial infection
Báo cáo y học: "Hypothalamic-pituitary-adrenal stress axis function and the relationship with chronic widespread pain and its antecedent" pdf
... 1) Random samples of 178, 463 and 80 subjects from each of these three groups, respectively, were telephoned and invited to the assessment of HPA axis function of which 131 (74%), 267 (58%) and ... composed of the evening and morning cortisol values; a 'post -stress cortisol' score that was composed of the post-dexamethasone and post-physical exam cortisol scores; and a 'post -stress difference' ... subjects, though there are no standardised methods of assessing HPA function in such studies We therefore decided to take a broad approach and used four measures of axis function: two that assessed...
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Báo cáo y học: "Japanese Encephalitis Virus wild strain infection suppresses dendritic cells maturation and function, and causes the expansion of regulatory T cells" doc
... alteration of phenotype and function of the JEV P3-infected DCs both in vitro and in vivo Our results indicated that JEV P3 severely infected DCs in vitro and in vivo, and the infection with JEV impaired ... replicated both in bmDCs and macrophages, and induced functional impairment of DCs through MyD88dependent and independent pathways which subsequently led to poor CD4+ and CD8+ T cell responses ... vitro and in vivo (A) The in vitro infected bmDCs and the spDCs from P3-challenged mice were harvested and analyzed with RT-PCR Bands shown are 467-bp PCR products specific for JEV (B) The bmDCs and...
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Tài liệu OXIDATIVE STRESS – MOLECULAR MECHANISMS AND BIOLOGICAL EFFECTS doc
... Semchyshyn and Volodymyr I Lushchak Chapter Oxidative and Nitrosative Stresses: Their Role in Health and Disease in Man and Birds 47 Hillar Klandorf and Knox Van Dyke Chapter Nitric Oxide Synthase and ... Oxidative Stress: Regulation of Nitric Oxide Synthase 61 Ehab M M Ali, Soha M Hamdy and Tarek M Mohamed Chapter Iron, Oxidative Stress and Health 73 Shobha Udipi, Padmini Ghugre and Chanda Gokhale ... Oxidative and Carbonyl Stresses: Molecular Mechanisms, Biological Effects and Therapeutic Strategies of Protection 29 Lipoxidation and glycoxidation are processes linking carbonyl and oxidative stresses...
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Tài liệu Cognitive function and brain structure correlations in healthy elderly East Asians doc
... test (Delis et al., 2001), and the Trail Making Test B (Reitan and Wolfson, 1985) Speed of processing was assessed with the TrailMaking Test A (Reitan and Wolfson, 1985) and the Symbol-Digit Modalities ... were standardized (z-transformed) and combined into six theoretically motivated composite scores (attention, verbal memory, visuospatial memory, speed of processing, executive functions and language) ... regions based on prior structural and functional imaging data that related structure to cognitive functions of interest (see Greenwood, 2007; Raz, 2005; Reuter-Lorenz and Lustig, 2005 for recent reviews)...
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Tài liệu Báo cáo khoa học: Structure determination and biochemical studies on Bacillus stearothermophilus E53Q serine hydroxymethyltransferase and its complexes provide insights on function and enzyme memory doc
... group and contained one monomer in the asymmetric unit Cell dimensions and details of data collection are shown in Table Expression and purification of bsSHMT and E53QbsSHMT The expression and purification ... supported by the Department of Science and Technology and DBT We thank Babu and James for their help during data collection VR and BSB thank the Council for Scientific and Industrial Research, Government ... Gly and Ser external aldimine complexes of E75Q and E75LrcSHMT, the electron density for the ligands was not well defined [15] In contrast, excellent electron density was observed for the ligands...
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Tài liệu Global Change and the Function and Distribution of Wetlands ppt
... II Sea Level Rise and Coastal Wetlands Response of Salt Marsh and Mangrove Wetlands to Changes in Atmospheric CO2, Climate, and Sea Level Karen McKee, Kerrylee Rogers, and Neil Saintilan ... Emissions and Wetlands Key Processes in CH4 Dynamics in Wetlands and Possible Shifts with Climate Change Hojeong Kang, Inyoung Jang, and Sunghyun Kim Part IV 99 Drought and Climate ... of Earth and Environment, Franklin and Marshall College, P.O Box 3003, Lancaster, PA 17604-3003, USA e-mail: chris.williams@fandm.edu B.A Middleton (ed.), Global Change and the Function and Distribution...
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Tài liệu Báo cáo khoa học: Relationships between structure, function and stability for pyridoxal 5¢-phosphate-dependent starch phosphorylase from Corynebacterium callunaeas revealed by reversible cofactor dissociation studies doc
... Analytical enzymes and enzyme substrates were specied in previous papers [1518] All other chemicals were of reagent grade and obtained from Sigma and Fluka Preparation of apo-Cc StP and apo-Ec MalP ... citrate and 0.1 M cysteine hydrochloride, in short, the resolution buffer Various pH values between 5.0 and 8.0 were tested, and a pH of 7.0 was chosen (see below) Prior to the resolution, CcStP and ... R226A and R242A mutants (Table 1), all enzymes were stable for h in the presence of mM potassium phosphate and potassium sulphate Reconstitutions with PLP of apo-Cc StP and mutants thereof, and...
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Tài liệu Báo cáo khoa học: Second messenger function and the structure–activity relationship of cyclic adenosine diphosphoribose (cADPR) doc
... hypoxanthine) and the diphospho-bridge, as they can be replaced by much simpler ether strands These ether strands mimic the distance between the nucleobase and the diphospho-bridge, but on the other hand ... permeabilized T-cells and induced both local and global Ca2+ signalling in intact T-cells [46] 8-Azido- and 8-NH2-cIDPRE performed similarly (Fig 4) whereas the halogenated compounds 8-Br- and 8-Cl-cIDPRE ... when [Ca2+]i is elevated above normal basal levels [25] On the other hand, ectoenzymes producing cADPR (such as CD38 and CD157) and transport systems for cADPR in the plasma membrane open the possibility...
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Tài liệu Báo cáo khoa học: Role of cleavage and shedding in human thyrotropin receptor function and trafficking pdf
... conformation between the receptor activated by cleavage and shedding on the one hand, and the receptor activated by the ligand on the other hand This may be due to different post-translational maturation ... ELISA ([28] and see Methods) on permeabilized cells Figure 2B shows a similar total expression of the wild-type and the truncated b1, b2 and TM409 receptors As shown in Fig 2A, the b1 and b2 mutant ... localized between amino acids 357 and 369 [15], in the E3 specific region of the receptor It does not interfere with receptor function and trafficking ([30], and data not shown) Measurement of...
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Overcoming Secondary Stress in Medical and Nursing Practice: A Guide to Professional Resilience and Personal Well-Being docx
... steps to appreciate, minimize, and learn from this stress to continue and even deepen—their roles as helpers and healers Understanding stress unique to health care work and developing a personal self-care ... this, if we face stress 28 Overcoming Secondary Stress in Medical and Nursing Practice Table 1-5 Level 2—Minor Stress Becomes Distress: Some Major Signs and Symptoms • Idealism and enthusiasm about ... Chronic and Acute Secondary Stress S econdary stress represents the stress caused by the pressures placed on professionals who care for others in need To understand its various causes, symptoms, and...
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Báo cáo khoa học: Protein transport in organelles: The composition, function and regulation of the Tic complex in chloroplast protein import pptx
... position and function of the long C-terminal tail on the other hand remains a matter of controversy [10,11,13–15] According to one hypothesis, the hydrophilic Tic110-Ct faces the stroma, where it functions ... binding site [10] These structures have been implicated with channel function (e.g in ligand-gated and voltage-gated K+ channels) [16], and thus could provide an explanation for the observed channel ... ATPase with a different function [24] Chaperones subsequently have been the main candidates for this ATPase activity and, indeed, members of the Hsp60 [chaperonin (Cpn)60] and Hsp100 (Hsp93) families...
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Báo cáo khoa học: Pherokine-2 and -3 Two Drosophila molecules related to pheromone/odor-binding proteins induced by viral and bacterial infections ppt
... both phk-2 and phk-3 is strongly reduced by ecdysone in vivo [41] These data support the hypothesis that Phk-2 and Phk-3 may interact with ligands different from Phk-1, and carry other functions ... tube containing two layers of caesium chloride (5% and 40%), and ultracentrifuged for 16 h at 36 000 g at 15 °C The virus band was collected and DCV was recovered by centrifugation (25 000 g, ... kept on standard medium at 22 °C, and counted daily Microscopic observations For observation of GFP expression patterns, live flies and larvae were anaesthetized with ether or on ice, and viewed...
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LUNG SURFACTANT FUNCTION AND DISORDER ppt
... of SP-A and SP-D 91 IV Potential Functions of SP-A and SP-D 91 V Structure of SP-A and SP-D 91 VI Ligands for SP-A and SP-D 93 VII Cells and Receptors 99 VIII Summary and Future ... Pediatric Nasal and Sinus Disorders, edited by Tania Sih and Peter A R Clement 200 Functional Lung Imaging, edited by David Lipson and Edwin van Beek 201 Lung Surfactant Function and Disorder, ... Zapol and K J Falke 25 Gas Mixing and Distribution in the Lung, edited by L A Engel and M Paiva 26 High-Frequency Ventilation in Intensive Care and During Surgery, edited by G Carlon and W S Howland...
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Báo cáo khoa học: The impact of G-protein-coupled receptor hetero-oligomerization on function and pharmacology pptx
... (2005) 2939–2946 ª 2005 FEBS Function and pharmacology of hetero-oligomers and a1b receptors [21], neurokinin NK1 and l opioid receptors [22], and the b2-adrenergic and d-opioid receptors [4] In ... dimeric ligands capable of acting as bivalent ligands The first publication showing the feasibility of constructing a bivalent ligand directed to heterodimeric receptors has come 2943 Function and pharmacology ... specificity, and consequently in determining the receptor fate and b-arrestin-mediated MAPK activation As discussed above for G-proteins, the mechanism and the stoichiometry by which GPCR and b-arrestin...
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Báo cáo khoa học: Essential roles of lipoyl domains in the activated function and control of pyruvate dehydrogenase kinases and phosphatase isoform 1 pot
... also transforms kinase and phosphatase function and regulation through serving as an anchoring scaffold, an adaptor protein directly abetting efficient phosphorylation and dephosphorylation, a ... interactions to the catalytic components (E1 and E3), kinase isoforms (PDK1, PDK2, PDK3, PDK4) and Ca2+-binding of PDP1 in translating and transmitting effector signals, and in modifying the sensitivity ... E1, successive Ôhand-over-handÕ transfer is proposed to proceed via a kinase dimer being successively bound to two lipoyl domains, randomly dissociating from one lipoyl domain and then rebinding...
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Báo cáo khoa học: Function and regulation of ABCA1 – membrane meso-domain organization and reorganization pptx
... [27,28] and PKA [38] and CK2 [43] phosphorylation sites are indicated (Not to scale.) FEBS Journal 278 (2011) 3190–3203 ª 2011 The Authors Journal compilation ª 2011 FEBS 3191 Function and regulation ... & Hayden MR (2003) Efflux and atherosclerosis: the clinical and biochemical impact of variations in the ABCA1 gene Arterioscler Thromb Vasc Biol 23, 1322–1332 Function and regulation of ABCA1 Oram ... Variations on a gene: rare and common variants in ABCA1 and their impact on HDL cholesterol levels and atherosclerosis Annu Rev Nutr 26, 105–129 Fitzgerald ML, Morris AL, Rhee JS, Andersson LP, Mendez...
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Báo cáo khoa học: A1–Protein Function and Ageing pptx
... of various stress responses to osmotic and hormonal stresses, cadmium(II) salt, sugars, and photooxidative stress induced by paraquat showed no significant difference between wild type and most ... 150 and 47 lm, for BChE w.t 320 and 23 lm for 2-PAM and HI-6, respectively Introduced mutations lowered oxime binding affinities for both oximes, and Ki were 590 and 87 lm for Y337A, 650 and 110 ... and have isoelectric point of 6.6, 6.1, 5.2 and 4.7 respectively Disulphide linked toxin and lectin subunits of HmRIP and isoforms have molecular weight of 28 and 34 kDa while that of HmRIP and...
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Báo cáo khoa học: "CLASSIFICATION OF MODALITY FUNCTION AND ITS APPLICATION ANALYSIS TO JAPANESE LANGUAGE" doc
... "rareru"), 3) hope Ctehoshii'" and "temoraitai"), 4~ request ,~"temorau"), 5) benefit ("tekureru teageru", and "teyaru") This is the most fundamental function and it simply adds the modality ... Natural Language, "Formal Semantics and Pragrnatics for Natural Languages", ed by F Guenthner and S J Schmidt, 1979 [6] Nakau, M : Tense, Aspect, and Modality, "Syntax and Semantics" 5, ed by M Shibatani, ... "rareru", %eiru", %a', where "dake", "rarern', "teiru", and "ta" are modality exp~'essions "Hiroko" and "yasai" have semantic categories, [human] and [food] respectively in each word frame [ or iterative...
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WETLANDS ECOSYSTEMS IN ASIA: FUNCTION AND MANAGEMENT pptx
... Conservation and Uses of Mangroves in Hong Kong and Mainland China N.F.Y Tam 11.1 Introduction 11.2 Mangrove Distribution and Characteristics in Hong Kong and Mainland China 11.3 Uses and Functions ... Natural Wetland Systems and Their Functions; II Wetland Biogeochemisty; III Wetland Management Strategies in Asia and IV Constructed Wetlands The basic information of natural wetland systems ... Carruthers, J.E Thomas, P.M Glibert Wetland Utilization and Protection in China Q.G Zhao, J Song 27 Ecological and Environmental Function of Wetland Landscape in the Liaohe Delta D.N Xiao, X.Z...
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