... compared the effects of a-T and its derivatives TA and TN with that of TS on LPS/IFN -induced NO production The additions of a-T, TA and TN did not induce NO production in the absence of LPS/IFN, ... by the coexistence of a-T, TA and TN (Figs and 4), but not ofthe antioxidants BHA and AsA These results suggested that active oxygens and free radicals did not participate in the TS effect, and ... column) The insert graph of (B) shows the inhibition effects of a-T, TA and TN on the enhancement by 50 lM TS of LPS -induced NO production Values are means ± SD (n ¼ 3) *P £ 0.01 effects of a-T and...
... ofcells plated was performed twice The coefficient for normalization was calculated from the level of ATP for the same amount of plated cells after days of plating in medium without growthfactors ... presented as percentage of mononuclear cells in Additional File Analysis ofthe number oftheprogenitorcells in circulation by HALO assay Cells expressing the CD34 and CD133 markers are associated ... hematopoietic stemcells Radiat Res 1968, 36(3):521-7 44 Vos O, Buurman WA, Ploemacher RE: Mobilization of haemopoietic stemcells (CFU) into the peripheral blood ofthe mouse; effects of endotoxin and other...
... supervisors Prof Teoh Swee-Hin and A/Prof Jerry Chan I would like to thank them for their constant sharing of knowledge and ideas, their patience and understanding, andthe many hours they have each ... upregulation of several angiogenic genes and secretion ofgrowthfactors Figure reproduced from Carmeliet and Jain (Carmeliet and Jain 2000) (B) Sprouting ofthe endothelial cells is induced, resulting ... the main characteristics of mature endothelial cellsand its progenitorcells Table 2-10 Comparison between UCB and adult PB-EPC in terms of its colony emergence, growthand vessel forming ability...
... exposure time, and type ofcells In general, O2 concentrations over 1%, rather than arresting thegrowthof most kinds of cells, promote the proliferation of some types ofcells There is increasing ... a potent regulator of various types ofstemcells [12] Therefore, the effects of hypoxia on thestemcells are extensive, cell-type specific, and O2-regulated The modulation of cell proliferation ... used The Institutional Animal Care and Use Committee (IACUC) ofthe Academy of Military Medical Science gave consent for the use of rats in all ofthe experiments Isolation and culture of NPCs Cells...
... known about the effects of chemotherapeutic agents on thecellsofthe CNS, in striking contrast to the extensive investigations on the effects of irradiation on the brain To investigate the biological ... for many ofthe more widely recognized neurological syndromes Despite the clear evidence ofthe neurotoxicity of at least some forms of chemotherapy, studies on the effects of chemotherapeutic ... of chemotherapeutic agents on defined neural populations? How does the sensitivity of primary neural cells compare with that of cancer cells? What are the in vivo effects of chemotherapy on the...
... mouse based on the variable sizes ofthe grafts injected and possibly due to the varying numbers of true stemcells present in the samples injected [22,23] Since vector transduced CD34+ cells gave ... continued to express EGFP throughout the experimental period when cultured in vitro in the presence ofcytokinesandgrowth factors, and as long as 70 days in vivo in SCID-hu mice The self-inactivating ... levels of transgene expression in a subpopulation of cells, or alternatively due to the presence of a small number of non-transduced cells in culture Nevertheless, the above results demonstrated the...
... cells, and generation ofinduced pluripotent stemcells (iPS) [11-13] We and others have determined that Sall4 exists as two isoforms (Sall4A and Sall4B), and they have unique and overlapping functions ... Interestingly, Sall4 is one ofthe few genes that are also involved in adult tissue stemcells [17,18], and its protein expression is always correlated with the presence ofstemandprogenitor cell populations ... LSK cellsand three mice received Sall4B treated LSK cells (a) The population of donor cells (Ly5.2+) in the peripheral blood ofthe recipient mice was examined by flow cytometry assays with the...
... level of EPCs between the EPO therapy and placebo-control group of 0.32%, and a standard deviation of circulating level of EPCs in EPO therapy was 0.7% A 20% rate of protocol violations and incomplete ... dysfunction [35] Therefore, our results strengthen the findings of previous studies [33-35] Taken together, the results ofthe present study not only corroborate that of our recent report [24], they also ... Barthel Index at 48 h after acute IS (Figure 2) On the other hand, a significant negative correlation was noted between the circulating level of EPCs (E and E3) and both modified Ranking Scale and...
... provide for the exchange of information between the Office and recipients of grants, con- tracts, and agreements under subsection (c), and be- 10 tween the Office and health professionals andthe 11 ... COMPOSITION. The Coordinating Com- 13 mittee shall be composed ofthe official designated 14 under subsection (a) andthe directors ofthe centers 15 and offices ofthe Agency 16 ‘‘(3) CHAIRPERSON. The official ... ESTABLISHMENT. The Secretary shall estab- 11 lish within the Office ofthe Administrator ofthe Health 12 Resources and Services Administration, an office to be 13 known as the Office of Women’s Health The...
... respondents made the hypothetical product choice and then read and judged the argument, they were asked to rate the importance ofthe issue andthe carefulness with which they read the argument There are ... 2001) and then to the consumer who selects the brand (McCracken 1989) Consumers therefore construct AESTHETIC PRODUCT CHOICE ANDTHE SELF and maintain self-concepts throughthe use of branded consumer ... coffee or not for the coffeemaker), or its level on a hedonic attribute (rating by consumers on comfort and ease of use for the mouse and rating by consumers on taste ofthe coffee for the coffeemaker)...
... feature in the regulation of cholesterol transport by AA andthe release of AA in a specialized compartment ofthecells could offer novel means for understanding the regulation of steroid synthesis, ... now by the inhibition in the induction of 5018 ACS4 [28] during the early response andthe inhibition of ACS4 and StAR inductions during the sustained phase In both phases, the presence of DBI ... acid-free bovine serum albumin Then, cells were incubated in either the presence or absence of mM 8Br-cAMP for 30 After washing the cells, they were scraped and nuclear and mitochondrial fractions...
... operationalize the implementation of changes, observe, and share their effect with other teams in the collaborative Other teams also implement the changes in their own environment and observe effect ... member ofthe QI team? Who selects the QI team? The QI team is usually selected by the director ofthe site with input from the coaches The QI team is composed of representatives of staff or other ... so as to meet the needs and expectations of clients andthe community Changing systems and processes to yield improvement entails that providers must understand the service system and its key processes...
... that ofthe wild-type and with an optimum pH of 6.5 A shift ofthe pH profile of about + 0.5–1.0 pH units and an optimum pH similar to that ofthe wild-type was observed for the H334G mutant in the ... Chemical 31P shifts ofthe PLP phosphate resonance signal of wild-type enzyme in the absence of ligand (d), in the presence of 20 mM arsenate (s), and in the presence of 20 mM arsenate and mM GL (.); ... rate for the wild-type (50 s)1; pH 7.0) andthe catalytic rates ofthe H334G mutant in the absence (0.0015 s)1; pH 6.5) andthe presence (0.0081 s)1; pH 7.0) of imidazole The lines indicate the trend...
... transferred to the Grand Chamber ofthe ECJ.55 When the oral procedure was re-opened, the Grand Chamber asked the parties and all the other Member States to give their views on: [T]he question ofthe extent ... the light ofthe Treaty rules rather than to remove them from the scope ofthe Treaty.79 In the light of these three reasons, he concluded that the Keck criteria were inappropriate and that the ... both for the driver ofthe vehicle and for other vehicles on the road, because the stability ofthe combination and its braking capacity would be affected.”138 The Grand Chamber ofthe ECJ had,...
... the bioferrofluid suspension CM and MRI participated in the design ofthe nanoparticle synthesis and preparation ofthe suspension, in the design ofthe study and to the writing of parts ofthe ... out the nanoparticle treatments to the plants andthe microscopy study, the processing of plant samples, and wrote the first manuscript draft LC carried out the synthesis of nanoparticles andthe ... contributed to the experimental design of nanoparticle synthesis and to the writing of parts ofthe manuscript DR participated in the design ofthe study and helped in experiments of nanoparticle...
... Price and Chinatown outlets These particular retail stores specialize in providing cheap knock-off clothes that capture the look and styling ofthe more famous designer products of Europe andthe ... issue may be the scale of consumption andthe surrender to the globalized mythos of ‘modern living’ throughthe acquisition of goods beyond those considered socially necessary The notion of being ... partners, using the internet and other new technologies, and consuming media in the form of music and films from abroad Lamaody was often referred to as originating from outside of Madagascar; and those...
... fraction ofthe harvested cells were then counted twice using a Coulter counter, and FACS profiled to normalize for the fraction of live transfected cellsThe remainder ofthecells were pelleted, and ... described in the Methods "M" indicates the migration position of standards used for quantitation, andthe amounts of standards loaded are indicated above each lane The identity ofthe transfected ... above and below the linear transfected DNA, with the position of FR andthe SV40 origin indicated The leading strands from the SV40 origin are indicated as long arrows, and Okazaki fragments as the...
... integument ofthe animal, and it seals off the injured area from the remainder ofthe crab’s open circulatory system The animal will often clot off and sacrifice an entire extremity (they have ... the exoskeleton ofthe crab immediately jeopardizes the integrity ofthe internal milieu ofthe organism Not only is there a real threat of loss of internal contents ofthe crab to the external ... consumption of clotting factorsand widespread deposition of fibrin clots throughout the microcirculation [2,19–21] The actions ofthe human coagulation system andthe innate immune system are strikingly...
... down-regulated in the SAMP8 animals and that the amelioration of cognitive deficits of SAMP8 implies the improvement ofthe system [13] These features of SAMP8 provide a useful animal model for the investigation ... removed from the pool The time spent in each ofthe four imaginary quadrants ofthe pool was recorded and analyzed with the SMART® system Quantitative real-time PCR where Tn and Tf represent the time ... Effects of CTS on the expression levels of VEGF and PDGF, angiogenic and neurotrophic factors, in the cerebral cortex of sham- and T2VO-SAMP Since the VEGF/PDGF family has angiogenic and neurotrophic...
... view ofthe relationship between teacher and pupil, that ofthe learned andthe learner, the possessor of knowledge andthe receiver of knowledge, the controller andthe controlled Teaching mathematics ... decided by the pattern of truth value flow in the system The system is Euclidean if the characteristic flow is the transmission of truth from the set of axiox 'downwards' to the rest ofthe system ... will look at the development of theories, the methodology ofthe programme, andthe nature of falsifiers 2.4.1 The Development of Theories Lakatos (1978) compares the Euclidean andthe quasi-empirical...