... disease (aGVHD), and was treated with corticosteroids and cyclosporine (CSA) At day +280, an inguinal × cm mass appeared and the presence of malignant cells was revealed upon biopsy At day +300, ... blasts after transplantation and the donor’s cells, supporting full engraftment of the stemcell transplant as well as the donor cell- origin of the AML blasts Figure Bone marrow smear after allo-SCT ... we report a case of a secondary AML developing from donor-derived cells in a breast cancer patient who underwent allogeneic stemcelltransplantation Donor cell leukemia is a rare although well-recognized...
... mg four times daily was added to the antibiotic regimen Apart from voriconazole, no medication associated with microangiopathia was administered On day after transplantation, the patient developed ... times a day, escalated up to 800 mg four times a day on day 13) and 80IU unfractionated heparin/kg/day on day There was no other causal treatment Despite early treatment, multiple organ failure ... V, Khan SP: Use of prophylactic anticoagulation and the risk of hepatic venoocclusive disease in patients undergoing hematopoietic stemcell transplantation: a systematic review and meta-analysis...
... lavage Diagn Microbiol Infect Dis 2005, 52:275-280 Fujimaki K, Mori T, Kida A, Tanaka M, Kawai N, Matsushima T, Kishi K, Fujisawa S, Sakura T, Yokota A, Kanda Y, Taguchi J, Akiyama H, Kanamori ... complication in a patient with relapsed Hodgkin's disease Whereas asymptomatic HHV6 reactivation is frequently reported in patients after allogeneic stemcell transplantation, severe disease is rare ... Marty FM, Schwartz RB: MR imaging of human herpesvirus-6-associated encephalitis in patients with anterograde amnesia after allogeneic hematopoietic stem- celltransplantation AJNR Am J Neuroradiol...
... lavage Diagn Microbiol Infect Dis 2005, 52:275-280 Fujimaki K, Mori T, Kida A, Tanaka M, Kawai N, Matsushima T, Kishi K, Fujisawa S, Sakura T, Yokota A, Kanda Y, Taguchi J, Akiyama H, Kanamori ... complication in a patient with relapsed Hodgkin's disease Whereas asymptomatic HHV6 reactivation is frequently reported in patients after allogeneic stemcell transplantation, severe disease is rare ... Marty FM, Schwartz RB: MR imaging of human herpesvirus-6-associated encephalitis in patients with anterograde amnesia after allogeneic hematopoietic stem- celltransplantation AJNR Am J Neuroradiol...
... synovial mesenchymal stemcelltransplantation in rabbits (a) Celltransplantation on a cartilage defect in a rabbit by the local adherent technique The osteochondral defect was faced upward (upper ... transplantation was performed days after the harvest Under anesthesia, the right knee joint was approached through a medial parapatellar incision, and the patella was dislocated laterally Full-thickness ... increasing the safety and economic feasibility Our study will advance and extend the clinical application of MSC-based cell therapy for cartilage injury Materials and methods Rabbits Skeletally mature...
... lymphoma (8%) Hodgkin disease (4%) Age at ATG treatment, years Mean (minimum, maximum) Statistical analysis The plasma concentrations of biochemical markers are reported as mean ± standard deviation ... Bayer, Leverkusen, Germany) Turbidimetry (Modular SWA) was also used for analyses of alanin amino-transferase (ALT), gammaglutamyl transferase (GGT), and bilirubin to assess liver function and ... France) CRP was measured by turbidimetry (Modular SWA; Roche, Basel, Switzerland) WBC count was analyzed from K3 EDTA (ethylenediaminetetraacetic acid) samples by a blood count analyzer (Advia...
... Myelodysplastic syndrome Relapsed AML Hematological malignancy ALL Malignant and nonmalignant disease Malignant and nonmalignant disease Acute leukemia Pretransplant Disease 904 days years 1361 days ... 2.5-12 Age Range of Patients (years) Hematological malignancy Malignant and nonmalignant disease β Thalassemia major Leukemia or myelodysplastic syndrome Malignant and nonmalignant disease ALL Myelodysplastic ... beta thalassemia major undergoing allogeneic blood and marrow transplantation Bone Marrow Transplantation, 35, 1095-1099 Jagasia, M., Giglia, J., Chinratanalab, W., Dixon, S., Chen, H., Frangoul,...
... consequently a more accurate assessment of transplant-related complications Author details Amanda Vansan Marangon, Ana Maria Sell, Daniela Maira Cardozo and Jeane E L Visentainer Immunogenetics Laboratory, ... CellTransplantation for the Treatment of Multiple Myeloma 195 Bhavana Bhatnagar and Ashraf Z Badros Chapter Proteasome Inhibition and Hematopoietic StemCellTransplantation in Multiple Myeloma ... Amanda Vansan Marangon, Ana Maria Sell, Daniela Maira Cardozo and Jeane E L Visentainer Chapter The Advanced HLA Typing Strategies for Hematopoietic StemCellTransplantation 45 Sun Yuying and...
... rabbit, cat (named Copycat) and monkey In 2006, reprogrammed murine iPSCs were reported by Takahashi and Yamanaka (Takahashi and Yamanaka, 2006) and in 2007 human iPSCs were reported (Takahashi ... Hematopoietic StemCellTransplantation for Adult Acute Lymphoblastic Leukaemia 267 Pier Paolo Piccaluga, Stefania Paolini, Francesca Bonifazi, Giuseppe Bandini, Giuseppe Visani and Sebastian Giebel Chapter ... contrast, activating KIRs (2DS and 3DS) interact with the DAP12 molecule, which has tyrosine-based activation motifs (ITAMs) that cause a cascade that results in an increase in cytoplasmic granulation...
... implantation and clinical pregnancy rate may have been Micromanipulation asaClinical Tool 301 increased following laser-mediated assisted hatching and a relatively large group of healthy babies ... children) was also diagnosed at 18 months in a ooplasmic Micromanipulation asaClinical Tool 289 transfer infant, a boy from a mixed sex twin Other centers applying ooplasmic transplantation have not ... than 20 babies There are a number of ways to transplant ooplasm, but the one initially used was a minor modification of the standard clinical ICSI technique A small portion of ooplasm was transferred...
... feasibility and transplant-related mortality Autoimmune Disease and Lymphoma Working Parties of the European Group for Blood and Marrow Transplantation, the European League Against Rheumatism and the ... supplemental inspired oxygen for the first time in several years Serologic measures associated with disease such as hypocomplementemia, antidouble-stranded DNA, and antinuclear antibodies normalize ... Baker S, Burt RK: Treatment of severe systemic lupus erythematosus with high-dose chemotherapy and haemopoietic stem- cell transplantation: a phase I study Lancet 2000, 356: 701-707 Traynor A, ...
... et al.: Autologous stemcelltransplantation for systemic lupus erythematosus Lupus 2004, 13:168-176 Saccardi R, Kozak T, Bocelli-Tyndall C, Fassas A, Kazis A, Havrdova E, Carreras E, Saiz A, ... autoantibody-producing plasma cells whereas other plasma cells remained unaffected [64] In lupus-prone mice, a significant decrease of ANAs was observed after allogeneic and, to a lesser extent, after syngeneic ... Czechowicz A, Kraft D, Weissman IL, Bhattacharya D: Efficient transplantation via antibody-based clearance of hematopoietic stemcell niches Science 2007, 318:1296-1299 Ogawa M, Matsuzaki Y, Nishikawa...
... transplantation MR Image of Mice after Intracranial SPIO-labeled hMSC Transplantation Before intracranial transplantation, 100 μL trypan blue (Sigma-Aldrich) was injected through foramen magnum ... Radhakrishnan RC, Bansal A, Dixit A, Rao DK, Das M, Jan M, Gupta PK, et al: Open-labeled study of unilateral autologous bone-marrow-derived mesenchymal stemcelltransplantation in Parkinson’s disease ... hMSCs transplantation proceeded as planned We found that rotarod performance of SCA2 transgenic mice was not significantly improved by serial intracranial hMSCs transplantation, and only a trend...
... served as the negative control DNA extraction Total DNA from distinct cell populations was extracted using the QIAamp DNA Blood Mini Kit (Qiagen, Germany) The quality of DNA was analyzed in 1% agarose ... leukemia patients (median age, 30.6 ± 10.2 years; range, 17-52 years; classified according to the French-American-British (FAB) criteria as 27 cases of acute lymphocytic leukemia (ALL) and 16 cases ... WB, Wang ZY: HLA-matched sibling transplantation with G-CSF mobilized PBSCs and BM decreases GVHD in adult patients with severe aplastic anemia J Hematol Oncol 3:51 Weinberg K, Blazar BR, Wagner...
... transplantation Unrelated cord blood has the advantage of easy procedure and immediate availability Current data show that a cord blood with a sufficient cell number and more than out of of A, ... Hematopoietic celltransplantation 2nd edition Edited by: Thomas ED, Blume KG, Forman SJ Malden, MA: Blackwell Science; 1999:503-512 Anasetti C: Transplantation of hematopoietic stem cells from alternate ... V, Handgretinger R, et al.: T -cell alloreactivity dominates natural killer cell alloreactivity in minimally Tcell-depleted HLA-non-identical pediatric bone marrow transplantation Br J Haematol...
... Kappa staining of BAL ment asa complication of relapsed disease after autologous stemcelltransplantation The presence of circulating plasma cells and hyperammonemia are both known to be indicators ... T, Akioka T, Miyamoto H, Oka S, Hara S, Yamano T, Takasu T, Tsuji M, Hanafusa T: Pulmonary parenchymal infiltrates in a patient with CD20-positive multiple myeloma European Journal of Haematology ... of advanced disease Plasma cell neoplasm should be kept in the differential diagnosis of any pulmonary infiltrate not responding to antibiotics or asa possible cause of skin nodules in a patient...
... synthetase (ASSN), certain tumour types like leukaemia have little ASSN activity and require exogenous asparagine This has led to the use of asparaginase, the enzyme that converts asparagine to aspartate ... diphosphate ; ALD, aldolase ; ALT, alanine aminotransferase; ATP, adenosine triphosphate; CS, citrate synthase; ENO, enolase; FA, fatty acids; FAD, flavin adenine dinucleotide; FASN, fatty acid synthase; ... ALD, aldolase ALT, alanine transaminase AKT, protein kinase B AML, acute myeloid leukemia AMP, adenosine monophosphate AMPK, AMP activated protein kinase ASCT, amino acid transporter ATP, adenosine...