stem cell therapy for heart failure using cord blood

DEVICE THERAPY FOR HEART FAILURE WHAT’S NEW IN 2008

Ngày tải lên : 10/03/2015, 17:36

... indicated for the treatment of New York Heart Association (NYHA) functional Class III or ambulatory Class IV heart failure symptoms on optimal recommended medical therapy I IIa IIb III IIb III For ... Pathophysiology of heart failure, illustrated by Venn diagram 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 Cardiac Resynchronization Therapy* in Patients With Severe Systolic Heart Failure ... without an ICD is reasonable for the treatment of NYHA functional Class III or ambulatory Class IV heart failure symptoms on optimal recommended medical therapy I IIaIIb III For patients with LVEF...

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Báo cáo hóa học: "Safety evaluation of allogeneic umbilical cord blood mononuclear cell therapy for degenerative conditions" pot

Ngày tải lên : 18/06/2014, 16:20

... batch information record including test results for sterility, mycoplasma and endotoxin Cell growth was regularly monitored and the inspection records updated accordingly Cells were harvested for ... using non-matched, allogeneic cord blood cells for regenerative medicine applications in absence of immune suppression would overcome several substantial hurdles existing today in stem cell therapy ... allogeneic cord blood therapy in absence of immune suppression/myeloablation This study presents for the first time a detailed safety analysis of using non-matched, allogeneic cord blood cells to...

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ENGINEERING THREE DIMENSIONAL CULTURE PLATFORMS FOR HUMAN ADIPOSE DERIVED STEM CELL THERAPY

Ngày tải lên : 09/09/2015, 11:18

... Injectable deliverey systems for stem cell therapy 20 2.4.1 Effect of mechanical cues on stem cells 21 2.4.2 Effect of biomolecular cues on stem cells 22 2.4.3 Hydrogels for stem cell therapy 23 2.4.4 ... fabrication and cell seeding 19 2.4 Injectable delivery systems for stem cell therapy Two kinds of approaches are primarily under consideration for stem cell therapies – (i) injection of stem cells with ... various types of stem cells for such stem cell based therapies, few of which are discussed in the following sections Stem cells are broadly classified into embryonic and adult stem cells based on...

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$báo cáo hóa học:" Non-expanded adipose stromal vascular fraction cell therapy for multiple sclerosis" pptx$

báo cáo hóa học:" Non-expanded adipose stromal vascular fraction cell therapy for multiple sclerosis" pptx

Ngày tải lên : 18/06/2014, 15:20

... Mesenchymal stem cells inhibit the differentiation of dendritic cells through an interleukin-6-dependent mechanism Stem Cells 2007, 25:2025-2032 English K, Barry FP, Mahon BP: Murine mesenchymal stem cells ... obtained before (Panels A and B), and six months after (Panel C) the stem cell treatment of patient MRI Images obtained before (Panels A and B), and six months after (Panel C) the stem cell treatment ... obtained before (Panels A and B), and seven months after (Panel C) the stem cell treatment of patient MRI Images obtained before (Panels A and B), and seven months after (Panel C) the stem cell treatment...

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Báo cáo sinh học: " Risk factors in the development of stem cell therapy" pdf

Ngày tải lên : 18/06/2014, 19:20

... accompanied by cell sorting to minimise the number of pluri/ multipotent stem cells in the cell preparation [86], or to separate tumourigenic stem cells from non-tumourigenic stem cells (by e.g cell sorting ... cultured cells, including stem cells These risk factors are not unique to stem cells and apply to all cell based medicinal products Donor history is of particular importance for stem cell lines ... Chemical and Genetic Approach for the Generation of Induced Pluripotent Stem Cells Cell Stem Cell 2008, 2:525-528 81 Uccelli A, Moretta L, Pistoia V: Mesenchymal stem cells in health and disease...

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o cáo hóa học:" Summit on cell therapy for cancer: The importance of the interaction of multiple disciplines to advance clinical therapy" ppt

Ngày tải lên : 20/06/2014, 04:20

... Summit on Cell Therapy for Cancer The meeting will include lectures on adoptive cellular therapy using tumor infiltrating lymphocytes (TIL), cytotoxic T cells and natural killer (NK) cells, reprogramming ... × 109 cell used for adoptive cytotoxic T cell and NK cell therapy Several groups are currently working to develop and validate methods to expand, TIL, T cells, engineered T cells and NK cell in ... cytotoxic T cells for melanoma therapy [8,9] Immune therapy of cancer has spread well beyond the treatment of melanoma The field of hematopoietic stem cell transplantation (HSCT) is moving from a cell...

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Báo cáo y học: "Hematopoietic stem cell transplantation for systemic lupus erythematosus" ppsx

Ngày tải lên : 09/08/2014, 01:23

... severe systemic lupus erythematosus with high-dose chemotherapy and haemopoietic stem- cell transplantation: a phase I study Lancet 2000, 356: 701-707 Traynor A, Burt RK: Haematopoietic stem cell ... with the same dose of cyclophosphamide without hematopoietic stem cell support, and also to hasten stem cell regeneration of the immune system under the umbrella of the ATG effect Based on the same ... stem cell support Competing interests None declared References 10 11 12 13 14 Marmont AM, van Lint MT, Gualandi F, Bacigalupo A: Autologous marrow stem cell transplantation for severe systemic...

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Báo cáo y học: " Cell therapy for autoimmune diseases" ppt

Ngày tải lên : 09/08/2014, 10:20

... acute renal failure by stem cell therapy – paracrine secretion versus transdifferentiation into resident cells: administered mesenchymal stem cells protect against ischemic acute renal failure through ... myeloid suppressor cell recruitment [62], thus accounting in some cases for the poor outcome of tumour vaccination strategies Mesenchymal stem cells Mesenchymal stem cells (MSC) are cells of stromal ... immune system is now a realistic alternative In the present article we review and discuss the current and future prospects for such cell- based therapies Hematopoietic stem cell transplantation for...

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Báo cáo y học: "Stem cell transplantation for rheumatic autoimmune diseases" potx

Ngày tải lên : 09/08/2014, 10:23

... European Group for Blood and Marrow Transplantation, et al.: Autologous stem cell transplantation for systemic lupus erythematosus Lupus 2004, 13:168-176 Saccardi R, Kozak T, Bocelli-Tyndall C, ... persistent donor NK -cell alloreactivity following nonmyeloablative allogeneic stem cell transplantation Blood 2007, 109:5524-5525 65 Tyndall A, Gratwohl A: Blood and marrow stem cell transplants ... peripheral blood stem cell (PBSC) grafts contain more T cells than BM grafts with a preserved CD4/CD8 ratio and a less activated immunophenotype [58] Recovery is significantly faster for CD4 cells,...

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Báo cáo y học: "A mouse embryonic stem cell bank for inducible overexpression of human chromosome 21 genes." ppsx

Ngày tải lên : 09/08/2014, 20:22

... mES cells, this system allows the efficient and long-term overexpression of the transgene in a dose- and time-dependent manner It is therefore suitable for systematic expression of HSA21 cDNAs Cell ... http://genomebiology.com/2010/11/6/R64 Our work has produced the first resource for systematic overexpression of single HSA21 genes in mES cells using an inducible system Our cell bank can be used to understand how much, and ... to assess the percentage of euploid cells Embryonic stem cell differentiation The EB3 cells and the parental line E14 cells [43] were allowed to differentiate using the 'hanging drop' method [44,45]...

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Báo cáo y học: "Allogeneic hematopoietic stem cell transplantation for acute leukemia with Gilbert’s syndrome" pptx

Ngày tải lên : 10/08/2014, 21:23

... Bilirubin level during chemotherapy and allogeneic hematopoietic stem cell transplantation Chronological dates of the treatment courses were indicated (A) the first cycle of chemotherapy of DA regimen ... for conditioning; Phenytoin for prophylaxis of busulfan’s side affect Tacrolimus; methotrexate and mycophenolate mofetil (0.5 g twice a day on days to +28) for GVHD prophylaxis; Caspofungin for ... the Asian-Pacific Society of Hematology; Member of Blood Branch of the Chinese Medical Association; Member of the Chinese hematopoietic stem cell transplant group; Standing Committee member of...

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báo cáo khoa học: "Current status of haploidentical stem cell transplantation for leukemia" pps

Ngày tải lên : 10/08/2014, 22:20

... show that a cord blood with a sufficient cell number and more than out of of A, B and DRB1 loci is also a good alternative source for stem cells However, the low cell dose of cord blood results ... and/or graft failure, which led to high TRM[16] The availability of techniques for positive selection of CD34 cells by using the CliniMACS system has provided enriched CD34+ stem cells with a ... CY/MeCCNU/ATG CSP/MMF/ MTX short 1.8 220 Not done 55% 47% 2-year 19% for SR 31% for HR 12% for SR 39% for HR 2-year 68% for SR 42% for HR Japan, 2006[39] Journal of Hematology & Oncology 2008, 1:27...

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Báo cáo y học: "Dendritic cell therapy for oncology roundtable conference Sandra Tuyaerts" doc

Ngày tải lên : 11/08/2014, 08:21

... should interact with T cells Jeffrey Weber therefore designed a system to attract T cells to the injection site and induce in this way and “artificial lymph nodal aggregate” for T cell priming To achieve ... immunerelated response pattern (as described for anti-CTLA4 therapy) Therefore, immune-related response criteria (irRC) may be more relevant than RECIST/WHO criteria for the assessment of anti-tumor activity ... responses, and nearly three fourths had T cell proliferative responses Survival was improved for patients who had an antibody response but not for those with a T cell response Although these data are...

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báo cáo khoa học: " Stem cell approaches for diabetes: towards beta cell replacement" potx

Ngày tải lên : 11/08/2014, 12:21

... of beta cells for replacement therapy Successes and challenges for islet transplantation (a) Embryonic or induced pluripotent stem cells The first successful transplantation of islet cells into ... to an adequate supply of beta cells for replacement therapy can be found in Box (b) Adult stem/ progenitor cells (islet neogenesis from duct cells or other precursor cells in the pancreas, or from ... search for other stem/ progenitor cells in the pancreas While much attention has been paid to duct cells as the potential origin of new islets, there has also been a search for other stem cells...

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Báo cáo khoa học: " Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin''''s disease: a case report" doc

Ngày tải lên : 12/08/2014, 04:21

... relapsed and two cycles of DexaBEAM with stem cell harvest were applied We performed high-dose chemotherapy according to the BEAM protocol On day twelve after stem cell reinfusion he developed mental ... respiratory failure and bilateral jugular vein thrombosis Foscarnet – treatment was continued until day 44 Cerebrospinal fluid and peripheral blood were both negative for HHV6b using PCR An oral therapy ... allogeneic stem cell transplantation, severe disease is rare in patients after autologous stem cell transplantation Nevertheless, in patients with severe complications of infections after autologous stem...

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Báo cáo khoa học: " Challenging complications of treatment – human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin''''s disease: a case report" ppsx

Ngày tải lên : 12/08/2014, 04:22

... relapsed and two cycles of DexaBEAM with stem cell harvest were applied We performed high-dose chemotherapy according to the BEAM protocol On day twelve after stem cell reinfusion he developed mental ... respiratory failure and bilateral jugular vein thrombosis Foscarnet – treatment was continued until day 44 Cerebrospinal fluid and peripheral blood were both negative for HHV6b using PCR An oral therapy ... allogeneic stem cell transplantation, severe disease is rare in patients after autologous stem cell transplantation Nevertheless, in patients with severe complications of infections after autologous stem...

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Báo cáo y học: " Cheyne-Stokes respiration in patients hospitalised for heart failure" doc

Ngày tải lên : 12/08/2014, 18:21

... informed consent Heart failure was diagnosed according to European Society of Cardiology guidelines for the diagnosis of heart failure [8] All patients had been stabilised following treatment for ... chronic heart failure Page of (page number not for citation purposes) Respiratory Research 2004, 5:14 admitted to hospital due to decompensated chronic heart failure are treated at the Heart Failure ... respiration Chest 1995, 107:952-958 The Task Force on Heart Failure of the European Society of Cardiology: Guidelines for the diagnosis of heart failure Eur Heart J 1995, 16:741-751 Alam M, Höglund...

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Biomimetic nanofiber stem cell composite for skin graft application

Ngày tải lên : 12/09/2015, 09:10

... full-thickness skin wounds, the epidermal stem cells in hair follicles for epidermal renewal, the basement membrane for cell migration and the blood vessels in dermis for nutrition supply are all destroyed, ... grafts for the capture of bone marrow-derived hematopoietic stem cells Proceedings of Materials and Processes for Medical Devices TM (MPMDTM) Conference and Exposition, 23-25 September 2007, California, ... blended for co-electrospinning to provide the skin grafts with appropriate mechanical stability and biomolecular cell recognition signals for cell- scaffold interactions d) A specific antibody for...

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Báo cáo hóa học: " Modulation of the major histocompatibility complex by neural stem cell-derived neurotrophic factors used for regenerative therapy in a rat model of stroke" ppt

Ngày tải lên : 18/06/2014, 16:20

... neural stem cell transplant A: reddish brown coloration of caspase III immunoreactivity along the ventricular lining of cells of ischemic rat having undergone neural stem cell transplant for four ... determining the copy number was performed using system software All measurements were performed in triplicate in two separate experiments Preparation of NSC for Transplant NSC at passage were ... http://www.translational-medicine.com/content/8/1/77 Page of 10 Figure Tracking of BrdU-labeled neural stem cells at passage six in the ischemic brain of rat having undergone cell therapy for four weeks A: a representative coronal section of...

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